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Condition: Aortic Stenosis

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Total 1228 results found since Jan 2013.

Aortic Valve Area, Stroke Volume, Left Ventricular Hypertrophy, Remodeling, and Fibrosis in Aortic Stenosis Assessed by Cardiac Magnetic Resonance Imaging: Comparison Between High and Low Gradient and Normal and Low Flow Aortic Stenosis Valvular Heart Disease
Conclusions— CMR confirmed overall accuracy of echocardiographic classification of AS but demonstrated that LG/LF and LG/NF AS have larger AVA, less LV hypertrophy, and similar focal fibrosis compared with HG/LF AS. This challenges the view that LG/LF AS is a more advanced state of AS.
Source: Circulation: Cardiovascular Imaging - November 19, 2013 Category: Radiology Authors: Barone-Rochette, G., Pierard, S., Seldrum, S., de Meester de Ravenstein, C., Melchior, J., Maes, F., Pouleur, A.-C., Vancraeynest, D., Pasquet, A., Vanoverschelde, J.-L., Gerber, B. L. Tags: CT and MRI, Echocardiography Valvular Heart Disease Source Type: research

Right Ventricular Function Is Associated with Left Ventricular Stroke Volume in Patients with Severe Aortic Stenosis and Preserved Ejection Fraction
ConclusionsRight ventricular systolic function assessed by TAPSE and FAC is significantly related to aortic valve flow in patients with severe AS and preserved LVEF.
Source: Echocardiography - December 1, 2015 Category: Cardiology Authors: George T. Charlton, Teresa Slomka, Wen‐Chih Wu, Gaurav Choudhary Tags: Original Investigation Source Type: research

Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Replacement —Effective in Stroke Prevention?
Transcatheter aortic valve replacement (TAVR) has become the mainstay of treatment for severe symptomatic aortic stenosis. Despite advances in device technology and procedural techniques, periprocedural stroke remains a severe complication of TAVR, affecting 2% of patients. The embolization of calcific debris from the degenerated aortic valve and atherosclerotic plaque from the aorta, both of which are manipulated during TAVR, is the likely mechanism of periprocedural stroke. Accordingly, cerebral embolic protection devices (EPDs) have been designed to prevent stroke by sequestering embolic debris during TAVR.
Source: JAMA Internal Medicine - February 24, 2020 Category: Internal Medicine Source Type: research

Association Of Stroke With Pattern Of Aortic Leaflet And Left Ventricular Outflow Tract Calcifications
Introduction: Stroke is a feared complication of transcatheter aortic valve replacement (TAVR) used for treatment of severe aortic stenosis. The risk of stroke has been associated with leaflet calcification burden. We aimed to investigate whether a specific pattern of aortic leaflet and left ventricular outflow tract (LVOT) calcification is associated with stroke risk.
Source: Journal of Cardiovascular Computed Tomography - July 1, 2021 Category: Radiology Authors: D. Brito, M. Shotwell, P. Agrawal, S. Patibandla, M. Kadiyala, Y. Hamirani, R. Daggubati, B. Raybuck, A. Kawsara, I. Zeb Source Type: research

Survival by stroke volume index in patients with low-gradient normal EF severe aortic stenosis
Conclusions Lower SVI is incrementally associated with mortality in LG severe AS with preserved EF. These findings have implications for classification of AS severity, identification of high-risk groups and subsequent management.
Source: Heart - December 12, 2014 Category: Cardiology Authors: Eleid, M. F., Sorajja, P., Michelena, H. I., Malouf, J. F., Scott, C. G., Pellikka, P. A. Tags: Editor's choice, Drugs: cardiovascular system, Echocardiography, Aortic valve disease, Clinical diagnostic tests, Epidemiology Valvular heart disease Source Type: research

Survival by stroke volume index in low-gradient normal EF severe aortic stenosis: insights into myocardial systolic dysfunction
To the Editor, We read with interest the recent article on survival by stroke volume index (SVI) in patients with low-gradient normal EF severe aortic stenosis, which demonstrated lower SVI is incrementally associated with mortality.1 The authors discuss a putative mechanism of low stroke volume (SV) secondary to concentric remodelling which results in reduced LV cavity size. This impedes LV diastolic filling culminating in diminished systolic function despite normal EF. The authors quote evidence of systolic impairment, for example reduced longitudinal strain, in similar cohorts with preserved EF.2 In the current study, t...
Source: Heart - December 12, 2014 Category: Cardiology Authors: Rodrigues, J. C. L., Dastidar, A. G., Rohan, S., MacIver, D. H. Tags: PostScript Source Type: research

Agreement between stroke volume measured by oesophageal Doppler and uncalibrated pulse contour analysis during fluid loads in severe aortic stenosis
Abstract The purpose of this analysis was to study agreement and trending of stroke volume measured by oesophageal Doppler and 3rd generation Vigileo during fluid loads in patients with severe aortic stenosis. Observational study in 32 patients (30 analyzed) scheduled for aortic valve replacement due to severe aortic stenosis. After induction of anesthesia and before start of surgery, hemodynamic registrations for 1 min were obtained before and after a fluid load. Agreement between stroke volume measured by oesophageal Doppler (SVOD) and Vigileo (SVVig) was evaluated in Bland–Altman plot and trending in four-qu...
Source: Journal of Clinical Monitoring and Computing - January 31, 2015 Category: Information Technology Source Type: research

Relationship Between Insulin-like Growth Factor Binding Protein-2 and Left Ventricular Stroke Volume in Patients with Aortic Stenosis
Conclusions In this study, we documented that lower IGFBP-2 levels are independently associated with lower SVi, a powerful predictor of worse outcomes in the mild to moderate AS population. Teaser In aortic stenosis (AS) patients, LV remodeling and function vary extensively from one patient to another. Considering the associations between circulating IGFBP-2 and markers of the metabolic syndrome, the aim of the study was to examine the relationship between circulating IGFBP-2 and left ventricle (LV) pump function as measured by stroke volume index in AS patients with preserved LV ejection fraction.
Source: Canadian Journal of Cardiology - April 30, 2015 Category: Cardiology Source Type: research

Diastolic dysfunction reduces stroke volume during daily's life activities in patients with severe aortic stenosis
Pathophysiologic consequences of left ventricular (LV) hypertrophy and fibrosis, as these occur in aortic stenosis, are elevated filling and left atrial (LA) pressures [1]. Depending on the time duration of pressure overload, LA volume increases proportionally to the degree of left ventricular (LV) diastolic dysfunction [2]. Elevated LA pressure aims to ensure adequate LV filling and, consequently, stroke volume but may return to normal levels during certain daily activities (e.g., cough, defecation, lifting a heavy or even medium load), which produce a preload reduction, possibly compromising LV both filling and stroke volume [1].
Source: International Journal of Cardiology - May 20, 2015 Category: Cardiology Authors: Maria Angela Losi, Raffaele Izzo, Eugenio Stabile, Anna Sannino, Grazia Canciello, Alessandra Giamundo, Francesca Musella, Plinio Cirillo, Mariella Prastaro, Maurizio Galderisi, Bruno Trimarco, Giovanni Esposito Tags: Letter to the Editor Source Type: research

Impact of stroke volume assessment by integrating multi-detector computed tomography and Doppler data on the classification of aortic stenosis
The prevalence of low flow low gradient (LFLG) severe aortic stenosis (AS) may be overrated due to underestimation of stroke volume in two-dimensional (2D) echocardiography. The implications of 3D imaging on stroke volume calculation for AS classification have not been elucidated. Integrating multi-detector computed tomography (MDCT) and Doppler data may improve diagnostic accuracy in patients with LFLG AS.
Source: International Journal of Cardiology - September 1, 2017 Category: Cardiology Authors: Barbara E. St ähli, Thomas Stadler, Erik W. Holy, Thi Dan Linh Nguyen-Kim, Lisa Hoffelner, Ladina Erhart, Slayman Obeid, Markus Niemann, Rolf Jenni, Sandra Hamada, Robert Manka, Thomas F. Lüscher, Francesco Maisano, Fabian Nietlispach, Thomas Frauenfeld Source Type: research

Impact of stroke volume on severe aortic stenosis in patients with normal left ventricular function
ConclusionPatients with LF AS had worse operative and long-term outcomes than those with NF, even though they had preserved LV function.
Source: General Thoracic and Cardiovascular Surgery - July 7, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research

827 Factors Associated With Stroke Post TAVI
Transaortic Valve Implantation (TAVI) has emerged as an alternate treatment option in selected patients with critical aortic stenosis. Periprocedural stroke remains an uncommon but catastrophic complication following TAVI. We evaluated clinical variables and imaging characteristics of patients with stroke following TAVI, compared with matched (CHA2DS2-VASC) controls.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: C. Reid, G. Gwivedi, G. Yong Source Type: research

Discrepancy of Aortic Valve Area Measurements by Doppler vs. Biplane Stroke Volume Measurements and Utility of Combining the Different Areas in Aortic Valve Stenosis  - The Asian Valve Registry.
CONCLUSIONS: Discrepancy in AVAI by Doppler vs. biplane method was significantly more pronounced with increased LV outflow tract flow velocity, shorter height, lower weight, older age and smaller LV cavity dimensions. Combining the AVAIs enabled mutual and incremental value in predicting events. PMID: 33208592 [PubMed - as supplied by publisher]
Source: Circulation Journal - November 19, 2020 Category: Cardiology Authors: Iwataki M, Kim YJ, Park SW, Ling LH, Yu CM, Okura H, Ha JW, Hozumi T, Tanaka H, Izumi C, Yuasa T, Song JK, Otsuji Y, Sohn DW Tags: Circ J Source Type: research

Prevalence of In-hospital Stroke Comparing MitraClip and Transcatheter Aortic Valve Implantation
Transcatheter aortic valve implantation (TAVI) and mitraclip (MC) are increasingly utilized for the treatment of aortic stenosis (AS) and mitral regurgitation (MR), respectively. Perioperative stroke is one of the most serious complications following TAVI given the valve calcification and possible embolization during valve implantation, and thus ongoing trials are assessing the use of embolic protection device following TAVI. On the other hand, no such trials are being conducted on MC as the evidence of stroke following MC is lacking and MC does not share the same etiology with TAVI 1.
Source: The American Journal of Cardiology - January 5, 2021 Category: Cardiology Authors: Anas M. Saad, Keerat Rai Ahuja, Omar M. Abdelfattah, Mohamed M. Gad, Toshiaki Isogai, Manpreet Kaur, Grant W. Reed, James Yun, Amar Krishnaswamy, Samir R. Kapadia Source Type: research

Dysarthria-Facial Paresis and Rostral Pontine Ischemic Stroke
We describe an acute, postoperative dysarthria-facial paresis. While the rare stroke syndrome has been described previously, we present an under-described clinical nuance to its presentation with a particularly clear imaging correlation. A 78-year-old, right-handed man with a past medical history of aortic stenosis presented after a transcatheter aortic valve replacement. Immediately postoperatively, no neurological deficits were noted. That evening, he described his speech as “drunken.” He was later noted to have a right lower facial droop in addition to the speech change. His speech exhibited labial, lingual, and (to...
Source: Case Reports in Neurology - March 10, 2022 Category: Neurology Source Type: research