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Condition: Thrombosis
Countries: Japan Health

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Total 297 results found since Jan 2013.

Not as Simple as Canker Sores
BY ​NANA P. MATSUMOTO, & DEREK MEEKS, DO​​A 16-year-old boy presented to a rural ED with a swollen jaw, painful blisters in the mouth, and earache for the past day. One week before, he had a fever with chills, sore throat, and dry coughs. He was not taking any medications, and his immunizations were up-to-date. He had a mild learning disorder but no significant past medical or surgical history.​An apthous ulcer, the most common and one of the earliest signs of Behçet's disease.The patient's vital signs were within normal limits, and his physical examination revealed anterior cervical lymphadenopathy, sinus con...
Source: The Case Files - October 11, 2017 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Congenital dysfibrinogenemia in a Japanese family with fibrinogen Naples (BβAla68Thr) manifesting as superior sagittal sinus thrombosis
This report highlights the occurrence of fibrinogen Naples that has caused severe thrombotic complications in a young member of a Japanese family.
Source: Blood Coagulation and Fibrinolysis - October 1, 2017 Category: Hematology Tags: Case Reports Source Type: research

Comparison of the CHADS2, CHA2DS2-VASc and R2CHADS2 Scores in Japanese Patients with Non-valvular Paroxysmal Atrial Fibrillation Not Receiving Anticoagulation Therapy.
Conclusion In Japanese patients with PNVAF, the CHADS2, CHA2DS2-VASc, and R2CHADS2 scores are all useful for the risk stratification of IS/SE cases. PMID: 28943575 [PubMed - as supplied by publisher]
Source: Internal Medicine - September 27, 2017 Category: Internal Medicine Tags: Intern Med Source Type: research

Clinical Characteristics and Long-Term Outcomes of Rotational Atherectomy  - J2T Multicenter Registry.
CONCLUSIONS: This study has provided the largest Japanese dataset for long-term follow-up of RA. Although RA in calcified lesions appears feasible with a high rate of procedural success, a high incidence of MACE was observed. PMID: 28931790 [PubMed - as supplied by publisher]
Source: Circulation Journal - September 21, 2017 Category: Cardiology Authors: Okai I, Dohi T, Okazaki S, Jujo K, Nakashima M, Otsuki H, Tanaka K, Arashi H, Okabe R, Nagura F, Nara Y, Tamura H, Kurata T, Kawashima H, Kyono H, Yamaguchi J, Miyauchi K, Kozuma K, Hagiwara N, Daida H Tags: Circ J Source Type: research

Genetic Variants of RAMP2 and CLR are Associated with Stroke.
CONCLUSIONS: This was the first study to investigate the relationships between ADM receptor genes (RAMP2 and CLR) and stroke in the light of gene-environment interactions in human. PMID: 28904253 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - September 16, 2017 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Utilization of Anticoagulant and Antiplatelet Agents Among Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention  - Retrospective Cohort Study Using a Nationwide Claims Database in Japan.
CONCLUSIONS: Among Japanese AF patients who underwent PCI, prescriptions for antiplatelet agents were more common than those for anticoagulant agents. The majority of study participants were classified as high risk, suggesting a need for a new risk classification that reflects the risk profiles of Japanese patients. PMID: 28883227 [PubMed - as supplied by publisher]
Source: Circulation Journal - September 7, 2017 Category: Cardiology Authors: Ono F, Tanaka S, Nakao YM, Kawakami K Tags: Circ J Source Type: research

E-088 Investigation of safety termination of antiplatelet therapy after lvis stent-assisted cerebral aneurysm coiling
Conclusion Termination of AT at 3 months postoperatively did not result in ischemic events among patients who underwent LSAC. Neointimal formation of Lvis stent may be a criterion for termination of AT without increasing the risk of ischemic event. Disclosures: K. Takayama: None. K. Myouchin: None. T. Wada: None. S. Kurokawa: None. K. Kichikawa: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Takayama, K., Myouchin, K., Wada, T., Kurokawa, S., Kichikawa, K. Tags: Electronic Poster Abstracts Source Type: research

Effects of Smoking on Ischemic Stroke, Intracranial Hemorrhage, and Coronary Artery Events in Japanese Patients With Non-Valvular Atrial Fibrillation.
Authors: Suzuki S, Otsuka T, Sagara K, Semba H, Kano H, Matsuno S, Takai H, Kato Y, Uejima T, Oikawa Y, Nagashima K, Kirigaya H, Yajima J, Kunihara T, Sawada H, Aizawa T, Yamashita T Abstract The effects of smoking on the prognosis of non-valvular atrial fibrillation (NVAF) patients are unclear.The Shinken Database 2004-11 (n = 17,517) includes all new patients visiting the Cardiovascular Institute between June 2004 and March 2012. Among these cases, 2,102 NVAF patients were identified. The effects of smoking on ischemic stroke (IS), intracranial hemorrhage (ICH), and coronary artery events including percutaneous c...
Source: International Heart Journal - July 15, 2017 Category: Cardiology Tags: Int Heart J Source Type: research

Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions
by Yuko Tashima, Fumiaki Banno, Toshiyuki Kita, Yasuyuki Matsuda, Hiroji Yanamoto, Toshiyuki Miyata Plasminogen (Plg) is a precursor of plasmin that degrades fibrin. A race-specific A620T mutation in Plg, also known as Plg-Tochigi, originally identified in a patient with recurrent venous thromboembolism, causes dysplasminogenemia with reduced plasmin activity. The Plg-A620T mutation is present i n 3–4% of individuals in East Asian populations, and as many as 50,000 Japanese are estimated to be homozygous for the mutant 620T allele. In the present study, to understand the changes of thrombotic phenotypes in individuals w...
Source: PLoS One - July 7, 2017 Category: Biomedical Science Authors: Yuko Tashima Source Type: research

Lipid Management in a Japanese Community:Attainment Rate of Target Set by the Japan Atherosclerosis Society Guidelines for the Prevention of Atherosclerotic Cardiovascular Diseases 2012.
CONCLUSIONS: Lipid management is inadequate in community-based settings, particularly, in subjects with CKD and secondary prevention. PMID: 27568728 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - August 30, 2016 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

High-Risk Atherosclerotic Cardiovascular Disease in a Real-World Employed Japanese Population: Prevalence, Cardiovascular Event Rates, and Costs.
CONCLUSIONS: ASCVD is not rare in Japan, even within a relatively young population of employed persons. Further, the total direct first-year cost burden of ASCVD in the employed Japanese population is high. These data may inform future economic assessments of new ASCVD treatments. PMID: 26289083 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - August 22, 2015 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research