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Condition: Multiple Sclerosis

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Total 1656 results found since Jan 2013.

Anomia in left hemisphere stroke, multiple sclerosis and Parkinson's disease - a comparative study
CONCLUSIONS: Anomia features have quantitative and qualitative similarities and differences across neurological conditions.PMID:37296078 | DOI:10.1080/09638288.2023.2219902
Source: Disability and Rehabilitation - June 9, 2023 Category: Rehabilitation Authors: Joana Kristensson Francesca Longoni Per Östberg Signe R ödseth Smith Sabina Åke Charlotta Saldert Source Type: research

Plasma levels of neuron specific enolase quantifies the extent of neuronal injury in murine models of ischemic stroke and multiple sclerosis.
CONCLUSIONS: Plasma NSE is a valid and simple experimental biomarker that allows quantifying the degree of neuronal injury in a non-invasive approach. PMID: 23932916 [PubMed - as supplied by publisher]
Source: Neurobiology of Disease - August 8, 2013 Category: Neurology Authors: Gelderblom M, Daehn T, Schattling B, Ludewig P, Bernreuther C, Arunachalam P, Matschke J, Glatzel M, Gerloff C, Friese MA, Magnus T Tags: Neurobiol Dis Source Type: research

Cognitive reserve in stroke and traumatic brain injury patients
Abstract Cognitive reserve (CR) is defined as the ability to cope with brain damage due to pre-existing cognitive processes or to the development of new compensatory processes. Existing research on CR is mostly based on the study of neurodegenerative disorders, such as Alzheimer’s disease. Recently, however, this construct has also been applied to other neurological conditions, including multiple sclerosis, Parkinson’s disease, epilepsy, stroke, and traumatic brain injury. The present review provides an overview of the studies that have investigated the influence of CR on neuropsychological outcome in stroke ...
Source: Neurological Sciences - September 26, 2014 Category: Neurology Source Type: research

Protective features of peripheral monocytes/macrophages in stroke.
This article is part of a Special Issue entitled: Neuro inflammation: A common denominator for stroke, multiple sclerosis and Alzheimer's disease, guest edited by Helga de Vries and Markus Swaninger. PMID: 26584587 [PubMed - as supplied by publisher]
Source: Biochimica et Biophysica Acta - November 12, 2015 Category: Biochemistry Authors: Gliem M, Schwaninger M, Jander S Tags: Biochim Biophys Acta Source Type: research

Imaging of Neuroinflammation in Alzheimer's Disease, Multiple Sclerosis and Stroke: Recent Developments in Positron Emission Tomography.
This article is part of a Special Issue entitled: Neuro Inflammation edited by Helga E. de Vries and Markus Schwaninger. PMID: 26643549 [PubMed - as supplied by publisher]
Source: Biochimica et Biophysica Acta - November 28, 2015 Category: Biochemistry Authors: Janssen B, Vugts DJ, Funke U, Molenaar GT, Kruijer PS, van Berckel BN, Lammertsma AA, Windhorst AD Tags: Biochim Biophys Acta Source Type: research

PRISM II: Effectiveness of Dextromethorphan 20 mg/Quinidine 10 mg (NUEDEXTA(R)) for Treatment of Pseudobulbar Affect Secondary to Dementia, Stroke, or Traumatic Brain Injury: Combined Results of a Multicenter Open-Label Study (P2.225)
Conclusion: The open-label PRISM II study supports DM/Q effectiveness for PBA irrespective of underlying etiology. Study supported by: Avanir Pharmaceuticals, Inc.Disclosure: Dr. Siffert has nothing to disclose. Dr. Hammond has nothing to disclose. Dr. Alexander has nothing to disclose. Dr. Cutler has received personal compensation for activities with Abbott, AstraZeneca, Bristol-Myers Squibb, Forest, GlaxoSmithKline, Lilly, Merck, Novartis, Ortho-McNeil-Janssen, Otsuka, Pamlab, Pfizer, Shire, and Sunovion. Dr. D'Amico has received personal compensation for activities with Avanir Pharmaceuticals, Inc. Dr. Doody has receive...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Siffert, J., Hammond, F., Alexander, D., Cutler, A., D'Amico, S., Doody, R., Sauve, W., Zorowitz, R., Davis, C., Shin, P., Ledon, F., Yonan, C., Formella, A. Tags: Aging and Dementia: Therapeutics Source Type: research

Effects of Functional Electrical Stimulation on Reducing Falls and Improving Gait Parameters in Multiple Sclerosis and Stroke
Conclusions The use of FES had an impact on gait, specifically reducing the number of falls and improving walking. A specific effect at the ankle joint was observed, increasing foot clearance during the swing phase of gait. This effect was not accompanied with a reduction in the energetic expenditure during walking in subjects with multiple sclerosis and stroke. Level of Evidence To be determined.
Source: PMandR - November 18, 2016 Category: Rehabilitation Source Type: research

Mental health and BIS/BAS dimensions in Parkinson's disease and multiple sclerosis patients and in stroke survivors
Publication date: 1 October 2018 Source:Personality and Individual Differences, Volume 132 Author(s): Włodzimierz Oniszczenko, Joanna Bitner-Szulc, Anna Szylberg, Ewelina Kuczko-Piekarska, Marzena Zaborowska, Sławomir Wawrzyniak Mental health dimensions were compared among 46 Parkinson's disease patients, 46 multiple sclerosis patients and 32 stroke survivors. In addition, the role of the behavioural activation system (BAS) and the behavioural inhibition system (BIS) as mediators between disorders and mental health was investigated. The sample consisted of 124 neurological patients: all Caucasian adults (73 females and ...
Source: Personality and Individual Differences - May 17, 2018 Category: Psychiatry & Psychology Source Type: research

Detection of early infarction signs with machine learning-based diagnosis by means of the Alberta Stroke Program Early CT score (ASPECTS) in the clinical routine
ConclusionFor ASPECTS assessment, the examined software may provide valid data in case of normal brain. It may enhance the work of neuroradiologists in clinical decision making. A final human check for plausibility is needed, particularly in patient groups with pre-existing cerebral changes.
Source: Neuroradiology - July 31, 2018 Category: Radiology Source Type: research

Experiences of people with stroke and multiple sclerosis and caregivers of a community exercise programme involving a healthcare-recreation partnership.
CONCLUSIONS: Group, task-oriented community-based exercise programmes incorporating a healthcare-recreation partnership may yield health benefits for exercise participants and caregivers. Results can guide programme evaluation, the nature and timing of education about such programmes, and efforts to address cost and transportation issues. Implications of rehabilitation Stroke and multiple sclerosis commonly cause balance and mobility limitations that can result in physical inactivity and further deterioration in health. Group, task-oriented community-based exercise programmes in which rehabilitation professionals train and...
Source: Disability and Rehabilitation - January 22, 2019 Category: Rehabilitation Authors: Merali S, Cameron JI, Barclay R, Salbach NM Tags: Disabil Rehabil Source Type: research

Factors affecting the usability of an assistive soft robotic glove after stroke or multiple sclerosis.
Conclusion: The study highlights important aspects for consideration in the further development of new soft hand robotics for sustained use in activities of daily living after a central nervous system lesion. PMID: 31993671 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - January 31, 2020 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Development and Preliminary Validation of a Pneumatic Focal Vibration System to the Mitigation of Post-Stroke Spasticity
This study will not only provide a potential tool to relieve post-stroke spasticity, but also contribute to improving the sensory and motor function of patients with other neurological diseases, e.g. spinal cord injury, multiple sclerosis, Parkinson and dystonia, etc.
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 5, 2021 Category: Neuroscience Source Type: research

The emerging role of FTY720 as a sphingosine 1 ‐phosphate analog for the treatment of ischemic stroke: The cellular and molecular mechanisms
Three important mechanisms for neuroprotective effects of FTY720 have been described. Functional antagonistic, functional agonistic and receptor-independent mechanisms. Here, we review these mechanisms in more details and describe animal model and in clinical trial studies AbstractFinding novel and effective drugs for the treatment of ischemic stroke is warranted because there is not a definitive treatment for this prevalent disease. Due to the relevance between the sphingosine 1-phosphate (S1P) receptor and several neurological diseases including ischemic stroke, it seems that fingolimod (FTY720), as an agonist of S1P rec...
Source: Brain and Behavior - May 10, 2021 Category: Neurology Authors: Maryam Naseh, Jafar Vatanparast, Ali Rafati, Mahnaz Bayat, Masoud Haghani Tags: REVIEW Source Type: research

Eagle Syndrome: A Rare Cause of Stroke in a Young Patient
We report the case of a 26-year-old man who presented to the emergency department because he noticed that his right hand had become clumsy. He first noticed this symptom five days before his presentation, but he noticed that his symptom had improved significantly since it began. He reported that he had episodes of neck pain and pain around the ear. He visited the family physician clinic several times for this complaint and was diagnosed as having a temporomandibular joint disorder. Neurological examination revealed decreased muscle strength in the right upper limb with a power of 4/5 along with a sensory deficit. The coord...
Source: Pain Physician - February 15, 2022 Category: Anesthesiology Authors: Hussain A Alobaidi Ali A Alfaran Hawa H Algazwi Fatimah I Alkhater Hussain M Alshooalah Abdulrahman K Alanzi Ibrahim A Almindil Abdullah K Alqasim Aisha A Faqeeh Amani A Almutairi Ghaida H Alnaqa Najla H Alnaqa Renad M Alasmari Razan M Almashouf Faisal Al Source Type: research