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Condition: Multiple Sclerosis

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Total 1656 results found since Jan 2013.

Patient-identified factors that influence spasticity in people with stroke and multiple sclerosis receiving botulinum toxin injection treatments.
CONCLUSION: Intrinsic and extrinsic triggers can influence the perception of spasticity differently depending on individual factors, severity, location (arm vs. leg), and distribution of spasticity (unilateral vs. bilateral). Clinicians can use the findings to better understand, educate, and treat people with stroke and MS. PMID: 25931667 [PubMed]
Source: Physiotherapy Canada - May 3, 2015 Category: Physiotherapy Authors: Cheung J, Rancourt A, Di Poce S, Levine A, Hoang J, Ismail F, Boulias C, Phadke CP Tags: Physiother Can Source Type: research

Subcutaneous Interferon- β1a Does Not Increase the Risk of Stroke in Patients with Multiple Sclerosis: Analysis of Pooled Clinical Trials and Post-Marketing Surveillance
ConclusionSafety data from both clinical trial and post-marketing settings indicate that treatment with sc IFN- β1a does not increase stroke risk in patients with MS.FundingMerck KGaA, Darmstadt, Germany.
Source: Advances in Therapy - November 1, 2018 Category: Drugs & Pharmacology Source Type: research

Risk of stroke in multiple sclerosis and neuromyelitis optic spectrum disorder: a Nationwide cohort study in South Korea
Conclusions The risk of stroke is increased in patients with MS and NMOSD and seemed comparable between the two conditions. This is the first study that estimates the risk of stroke in patients with MS and NMOSD within the same population.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2022 Category: Neurosurgery Authors: Cho, E. B., Yeo, Y., Jung, J. H., Jeong, S.-M., Han, K.-d., Shin, D. W., Min, J.-H. Tags: Multiple sclerosis Source Type: research

Increased risk of ischaemic stroke among patients with multiple sclerosis
ConclusionsMultiple sclerosis is declared to be associated with an increased risk in developing stroke, which requires closer attention to this group of patients for stroke prevention, especially in the younger population.
Source: European Journal of Neurology - November 29, 2014 Category: Neurology Authors: C.‐H. Tseng, W.‐S. Huang, C.‐L. Lin, Y.‐J. Chang Tags: Original Article Source Type: research

Changing course of Multiple Sclerosis (MS) after stroke: Excessive disease activity in a MS patient after cerebral infarction (P1.122)
CONCLUSIONS: This is a rare case of MS exacerbation after stroke in a patient with long-standing MS. The clear temporal relation with an increase of MS disease activity after stroke suggests possible interactions. One explanation could be an opening of the blood brain barrier after stroke with influx of activated immune cells into the central nervous system and consecutive MS exacerbation.Disclosure: Dr. Poellmann has received personal compensation for activities with Pfizer Inc., Novartis, Biogen Idec, and Merck Serono. Dr. Starck has nothing to disclose. Dr. Kümpfel has received personal compensation for activities ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Poellmann, W., Starck, M., Kuempfel, T., Koehler, J. Tags: MS and CNS Inflammatory Diseases: Symptoms, Specific Symptomatic Treatment, Co-morbidities, and Costs Source Type: research

Reserve, Resilience and Recovery in Stroke: A Meta-Narrative Review (P3.199)
Conclusion: There is an urgent need to individualize outcomes in stroke systematically by implementing well validated concepts from various related fields to improve patient centered decision-making in acute stroke care.Disclosure: Dr. Dangayach has nothing to disclose. Dr. Grewal has nothing to disclose. Dr. Gordon has nothing to disclose. Dr. Mayer has received research support from Non-Invasive Medical Systems, Inc. and General Electric.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Dangayach, N., Grewal, H., Gordon, E., Mayer, S. Tags: Neurocritical Care: Clinical Science Source Type: research

Inherited and Uncommon Causes of Stroke
This article is a practical guide to identifying uncommon causes of stroke and offers guidance for evaluation and management, even when large controlled trials are lacking in these rarer forms of stroke. Recent Findings: Fabry disease causes early-onset stroke, particularly of the vertebrobasilar system; enzyme replacement therapy should be considered in affected patients. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), often misdiagnosed as multiple sclerosis, causes migraines, early-onset lacunar strokes, and dementia. Moyamoya disease can cause either ischemic or he...
Source: CONTINUUM: Lifelong Learning in Neurology - February 1, 2017 Category: Neurology Tags: Review Articles Source Type: research

Characteristics of Code Stroke Cases in a Level 1 Trauma U.S. Military Treatment Facility: Comparison with a Civilian Stroke Center (P3.265)
Conclusions:The proportion of code strokes ultimately diagnosed with AISor TIA in our facility is lower than that reported in a civilian stroke center, and the proportion of functional diagnoses is higher. Further studies are needed to describe the reasons for these differences, which may be unique to military populations.Disclosure: Dr. Koehn has nothing to disclose. Dr. Williams has nothing to disclose. Dr. Chao has nothing to disclose. Dr. Frattalone has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Koehn, T., Williams, J., Chao, W., Frattalone, A. Tags: Cerebrovascular Disease Epidemiology Source Type: research

Multiple Sclerosis and Stroke (P6.169)
Conclusion: There are consistent differences between the rates of ischemic stroke and TIA in patients with MS compared to those without MS, possibly indicating common inflammatory mechanisms.Disclosure: Dr. Sung has nothing to disclose. Dr. Amezcua has received personal compensation for activities with Biogen Idec, Questcor, Novartis and Acorda Therapeutics. Dr. Amezcua has received research support from Novartis and Acorda Therapeutics. Dr. Cen has nothing to disclose. Dr. Krug has nothing to disclose. Dr. Sanossian has received personal compensation for activities with Boehringer-Ingelheim Pharmaceutical Inc.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Sung, E., Amezcua, L., Cen, S., Krug, A., Sanossian, N. Tags: Multiple Sclerosis Symptoms and Comorbidities Source Type: research

The impact of robot-mediated adaptive I-TRAVLE training on impaired upper limb function in chronic stroke and multiple sclerosis.
CONCLUSIONS: Robot-mediated training resulted in improved movement coordination in both groups, as well as clinical improvement in pwMS. Absence of functional improvements in stroke patients may relate to severe upper limb dysfunction at baseline. Implications for Rehabilitation Robot-mediated training improved strength, active range of motion and upper limb capacity in pwMS. Robot-mediated therapy allows for adapted training difficulty. PMID: 28125300 [PubMed - as supplied by publisher]
Source: Disability and Rehabilitation. Assistive Technology. - January 25, 2017 Category: Rehabilitation Authors: Maris A, Coninx K, Seelen H, Truyens V, De Weyer T, Geers R, Lemmens M, Coolen J, Stupar S, Lamers I, Feys P Tags: Disabil Rehabil Assist Technol Source Type: research

UCLA forms collaboration with Yuyu Pharma to develop drug for stroke recovery
UCLA has formed a research collaboration with South Korea-based Yuyu Pharma to develop drugs that could help people recover after a stroke.Yuyu will develop drug candidates and UCLA researchers will conduct preclinical trials that could lead to further development of new compounds.Leading the research for UCLA are Istvan Mody, a distinguished professor of neurology; Varghese John, a professor of neurology and the principal investigator at theDrug Discovery Lab at UCLA; and Dr. S. Thomas Carmichael, chair of the UCLA department of neurology.There is currently no medical therapy that promotes recovery in the brain after it h...
Source: UCLA Newsroom: Health Sciences - March 16, 2021 Category: Universities & Medical Training Source Type: news

Reliability and validity of Six-Spot Step Test (SSST) in stroke survivors
CONCLUSIONS: The SSST was a reliable test and showed a significant correlation with FMA-LE scores, BBS scores, and TUG test times in stroke survivors.CLINICAL REHABILITATION IMPACT: The SSST can be used to assess the advanced balance control of stroke survivors.PMID:34128605 | DOI:10.23736/S1973-9087.21.06799-X
Source: European Journal of Physical and Rehabilitation Medicine - June 15, 2021 Category: Rehabilitation Authors: Tai Wa Liu Shamay S Ng Ka-Yuen Cheung Ming-Yeung Cheung Ryan N Hung Man-Fai Lam Adrian T Wong Cynthia Y Lai Mimi M Tse Source Type: research