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Condition: Multiple Sclerosis

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Total 1656 results found since Jan 2013.

Neuropsychiatric disorders among Syrian and Iraqi refugees in Jordan: a retrospective cohort study 2012–2013
Conclusions: Neuropsychiatric disorders, including those traditionally considered outside the purview of refugee health, are an important burden to health among Iraqi and Syrian refugees. Possible interventions could include stroke risk factor reduction and targeted medication donations for multiple sclerosis, epilepsy, and schizophrenia.
Source: Conflict and Health - March 29, 2015 Category: Global & Universal Authors: Erica McKenziePaul SpiegelAdam KhalifaFarrah Mateen Source Type: research

Interaction of astrocytes and T cells in physiological and pathological conditions.
This article is part of a Special Issue entitled SI: Cell Interactions In Stroke. PMID: 25813828 [PubMed - as supplied by publisher]
Source: Brain Research - March 23, 2015 Category: Neurology Authors: Xie L, Yang SH Tags: Brain Res Source Type: research

Manifestations of an Uncommon Pontine Insult, Eight-and-a-Half Syndrome (P1.029)
CONCLUSIONS: EHS involves a specific constellation of clinical findings which include OHS and LMN facial palsy, all ipsilateral to the side of the lesion at the level of the pons. On the basis of our review, true EHS is a very rare manifestation. EHS variants, while still unique, are more common.Disclosure: Dr. mannel has nothing to disclose. Dr. Saada has nothing to disclose. Dr. Antonios has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Mannel, R., Saada, F., Antonios, N. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Neuropsychiatric disorders among Syrian and Iraqi refugees in Jordan, 2012-2013: A retrospective, cohort study (P2.324)
CONCLUSIONS:There is a need for long-term planning and financing for neuropsychiatric disorders traditionally considered outside of refugee health. Possible interventions may include stroke risk factor reduction and targeted medication donations for multiple sclerosis, epilepsy, and schizophrenia. Study Supported by: No funding recieved.Disclosure: Dr. McKenzie has nothing to disclose. Dr. Spiegel has nothing to disclose. Dr. Khalifa has nothing to disclose. Dr. Mateen has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: McKenzie, E., Spiegel, P., Khalifa, A., Mateen, F. Tags: Global Neurology Source Type: research

How often is CADASIL diagnosed as multiple sclerosis? (P4.076)
CONCLUSIONS: CADASIL presents in young adults with subcortical ischemic events. Clinically, similar to MS, these are episodes of recurrent acute focal neurologic deficit with partial or complete recovery. MRI shows diffuse asymmetric T2 white matter abnormalities in periventricular and subcortical white matter. With advent of immune modulating therapy, MS has become more amenable to treatment whereas there is no treatment for CADASIL, which may make clinicians more inclined to diagnose MS. Close attention must be paid to history of migraine with aura as well as family history of migraine, stroke and dementia to accurately ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Sathe, S., Nunziato, E. Tags: MS and CNS Inflammatory Diseases: CNS Inflammatory Diseases and Differential Diagnosis Source Type: research

Risks of Epilepsy During Pregnancy
Epilepsy is a common disease that affects 1 in 26 individuals in their lifetime. According to a National Institute of Neurological Disorders and Stroke assessment, with 2 million affected individuals, epilepsy ranks only fourth to migraine, stroke, and Alzheimer disease in the prevalence of neurological disorders. Epilepsy affects more people than autism, amyotrophic lateral sclerosis, cerebral palsy, multiple sclerosis, and Parkinson disease combined. Approximately 0.3% to 0.5% of all pregnancies are among women with epilepsy (WWE). The risks during pregnancy in WWE have been uncertain.
Source: JAMA Neurology - July 6, 2015 Category: Neurology Source Type: research

New therapeutic option for drop foot with the ActiGait peroneal nerve stimulator – A technical note
Publication date: Available online 9 July 2015 Source:World Neurosurgery Author(s): K. Daniel Martin , Witold Polanski , Gabriele Schackert , Stephan B. Sobottka A drop foot occurs in up to 20% of stroke patients and leads to an increased risk of falls. Until recently, only a foot orthosis or surface stimulation were able to improve the gait of these patients. Recent studies have shown that direct peroneal nerve stimulation with an implantable four-channel peroneal nerve stimulator (ActiGait) allows independent electrode adjustment and leads to better functional results and an improved quality of life. The application of...
Source: World Neurosurgery - July 10, 2015 Category: Neurosurgery Source Type: research

E-086 non-ischemic etiologies by ct perfusion
ConclusionThe radiologist should be aware of the imaging findings of etiologies which may mimic an acute ischemic stroke on CT perfusion imaging.DisclosuresM. Chehab: None. J. Wilseck: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Chehab, M., Wilseck, J. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Metaboreflex activity in multiple sclerosis patients
Conclusion It was concluded that MS patients have an impaired capacity to increase stroke volume (SV) in response to low level metaboreflex, even if they could sustain the MBP response by vasoconstriction. This was probably a consequence of their chronic physical de-conditioning.
Source: European Journal of Applied Physiology - October 1, 2015 Category: Physiology Source Type: research

Intrathecal Baclofen Dosing Regimens: A Retrospective Chart Review
ConclusionSignificant differences in dosing were found between diagnoses and trended to differ by ambulatory status at the end of the study, and similar trends could be observed in achieving initial stable dose.
Source: Neuromodulation: Technology at the Neural Interface - October 1, 2015 Category: Biotechnology Authors: Jacob S. Clearfield, Mary Elizabeth S. Nelson, John McGuire, Lisa E. Rein, Sergey Tarima Tags: Clinical Research Source Type: research

Evidence for the Importance of Vitamin D Status in Neurologic Conditions
Opinion statement Vitamin D status has been proposed as relevant to many neurological disorders. Data suggest that vitamin D may be important for the development of the nervous system, and it also plays a role in neuroimmunology and neuroprotection. Lower levels of circulating 25-hydroxyvitamin D have been linked with increased risk of multiple sclerosis (MS) and Alzheimer’s disease (AD). While people with amyotrophic lateral sclerosis (ALS), Parkinson’s disease (PD), and stroke have lower vitamin D levels than those without the diseases, it is unclear if this is because hypovitaminosis D contributes to disea...
Source: Current Treatment Options in Neurology - November 4, 2015 Category: Neurology Source Type: research

"Time is brain" in relapsing remitting multiple sclerosis : Current treatment concepts in immunotherapy.
DISCUSSION: For MS a "time is brain" concept would comprise an early initiation of first line therapy as well as sensitive and structured monitoring of disease activity under therapy in conjunction with a low threshold for timely treatment optimization to achieve sustained freedom from measurable disease activity. This approach may substantially improve the long-term outcome in patients who show insufficient response to platform therapies. The intersectorial collaboration in regional MS care networks involving office-based neurologists and specialized MS centers may facilitate the timely use of highly active therapies with...
Source: Der Nervenarzt - November 12, 2015 Category: Neurology Authors: Linker R, Kallmann BA, Kleinschnitz C, Rieckmann P, Mäurer M, Schwab S Tags: Nervenarzt Source Type: research

Novel Derivatives of Docosahexaenoylethanolamide as Therapeutics for Neuronal Disorders
This technology provides derivatives of Docosahexaenoylethanolamide (synaptamide or DEA) which have increased potency and hydrolysis resistance as compared to DEA (structures of these derivatives are available upon request), as well as methods of using these derivatives to promote neurogenesis, neurite growth, and/or synaptogenesis. Docosahexaenoic acid (DHA), an n-3 polyunsaturated fatty acid that accumulates in the brain during development, has been shown to play a key role in learning and memory development. Studies have also shown that DEA, a metabolite derived from DHA is very potent in accelerating neuronal growth an...
Source: NIH OTT Licensing Opportunities - January 24, 2013 Category: Research Authors: admin Source Type: research

Dual mobility cup for prevention of early total hip arthroplasty dislocation in patients with neurological disorders
Conclusion The dual mobility cup is effective in the prevention of early dislocation in patients with muscle weakness due to neurological disorders. Long-term follow-up is needed for the assessment of late dislocation, as well as the rate of loosening in this group of patients.
Source: European Orthopaedics and Traumatology - November 21, 2015 Category: Orthopaedics Source Type: research

Effects of whole body vibration on muscle spasticity for people with central nervous system disorders: A systematic review.
CONCLUSION: Whole-body vibration may be useful in reducing leg muscle spasticity in cerebral palsy but this needs to be verified by future high quality trials. There is insufficient evidence to support or refute the notion that whole-body vibration can reduce spasticity in stroke, spinocerebellar ataxia or multiple sclerosis. PMID: 26658333 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - December 11, 2015 Category: Rehabilitation Authors: Huang M, Liao LR, Pang MY Tags: Clin Rehabil Source Type: research