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Condition: Osteoarthritis

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Total 270 results found since Jan 2013.

A systematic review of behavioural techniques used in nutrition and weight loss interventions among adults with mobility‐impairing neurological and musculoskeletal conditions
Summary Obesity is a common comorbidity in adults with mobility‐impairing neurological and musculoskeletal conditions, such as stroke and arthritis. The interaction between mobility impairments and environmental factors often compromises motivation and ability to engage in healthy behaviours. Such difficulties to engage in healthy behaviours can result in energy imbalance, weight gain and a cycle of functional declines; i.e. obesity can exacerbate mobility impairments and symptoms and increase the likelihood of other comorbid conditions, all of which make it more difficult to engage in healthy behaviours. To help disrupt...
Source: Obesity Reviews - September 30, 2014 Category: Eating Disorders and Weight Management Authors: M. A. Plow, S. Moore, M. Elaine Husni, J. P. Kirwan Tags: Obesity Treatment Source Type: research

Outcomes of dual-mobility acetabular cup for instability in primary and revision total hip arthroplasty
Conclusions Even though postoperative hip stability depends on several factors other than design-related ones, our study shows promising early results for reducing the risk of instability in this challenging group of patients undergoing primary and revision hip arthroplasty. Level of evidence IV.
Source: Journal of Orthopaedics and Traumatology - October 21, 2014 Category: Orthopaedics Source Type: research

Experiential or behavioral processes: Which one is prominent in physical activity? Examining the processes of change 1 year after an intervention of therapeutic education among adults with obesity
Obesity is recognized as a growing epidemic with the worldwide body mass index (BMI) increasing by 0.5kg/m2 per decade since 1980 [1]. It is associated with increased total mortality and increased risks of disease or death from diabetes, ischemic heart disease and ischemic stroke, cancers, chronic kidney disease, and osteoarthritis [2]. Beneficial effects of physical activity (PA) on body weight and global health have now been clearly proven and besides diet and behavior therapy, PA is considered as a cornerstone of weight management for overweight/obese adults [3–5].
Source: Patient Education and Counseling - August 13, 2014 Category: Global & Universal Authors: A.J. Romain, V. Attalin, A. Sultan, C. Boegner, C. Gernigon, A. Avignon Tags: Intervention Source Type: research

Natural anti-obesity agents
Publication date: Available online 14 June 2014 Source:Bulletin of Faculty of Pharmacy, Cairo University Author(s): Gamal A. Mohamed , Sabrin R.M. Ibrahim , Ehab S. Elkhayat , Riham Salah El Dine Obesity is a complex disease caused by the interaction of a myriad of genetic, dietary, lifestyle, and environmental factors, which favors a chronic positive energy balance, and leads to increased body fat mass. The incidence of obesity is rising at an alarming rate and is becoming a major public health concern with incalculable social costs. Indeed, obesity facilitates the development of metabolic disorders such as diabetes, hy...
Source: Bulletin of Faculty of Pharmacy, Cairo University - October 13, 2014 Category: Drugs & Pharmacology Source Type: research

Adverse outcomes after total and unicompartmental knee replacement in 101 330 matched patients: a study of data from the National Joint Registry for England and Wales
Publication date: 18–24 October 2014 Source:The Lancet, Volume 384, Issue 9952 Author(s): Alexander D Liddle , Andrew Judge , Hemant Pandit , David W Murray Background Total knee replacement (TKR) or unicompartmental knee replacement (UKR) are options for end-stage osteoarthritis. However, comparisons between the two procedures are confounded by differences in baseline characteristics of patients undergoing either procedure and by insufficient reporting of endpoints other than revision. We aimed to compare adverse outcomes for each procedure in matched patients. Methods With propensity score techniques, we compared ma...
Source: The Lancet - October 17, 2014 Category: Journals (General) Source Type: research

Prevalence and risk factors of dry eye disease in a British female cohort
Conclusions DED is common and increases with age within this cohort of female twins. We confirmed established risk factors for the first time in a British population, and found important risk factors that might relate to an underlying aetiology involving chronic pain predisposition or somatisation.
Source: British Journal of Ophthalmology - November 14, 2014 Category: Opthalmology Authors: Vehof, J., Kozareva, D., Hysi, P. G., Hammond, C. J. Tags: Lens and zonules, Press releases, Neurology Original articles - Clinical science Source Type: research

Risk Factors for Falls in Older Korean Adults: The 2011 Community Health Survey.
In conclusion, age, female sex, marital status, residence location, self-rated health, stress, and several chronic conditions were significantly associated with the risk for falls in the older Korean adults. Our findings suggest that these risk factors should be addressed in public health policies for preventing falls. GRAPHICAL ABSTRACT: PMID: 25408578 [PubMed - as supplied by publisher]
Source: J Korean Med Sci - November 1, 2014 Category: Journals (General) Authors: Choi EJ, Kim SA, Kim NR, Rhee JA, Yun YW, Shin MH Tags: J Korean Med Sci Source Type: research

Prolonged risk of subtrochanteric and diaphyseal femur fractures after discontinuing alendronate treatment: A nationwide nested case-control study in Taiwan
Conclusion Discontinuation of alendronate therapy did not reduce the risk of subtrochanteric femoral fractures until it was discontinued for >5 years. In conclusion, alendronate use significantly increased the risk of subtrochanteric femoral fractures, and the risk may persist for 5 years after discontinuation.
Source: Journal of Clinical Gerontology and Geriatrics - November 27, 2014 Category: Geriatrics Source Type: research

Health care costs attributable to overweight calculated in a standardized way for three European countries
This article presents a tool to calculate health care costs attributable to overweight in a comparable and standardized way. The purpose is to describe the methodological principles of the tool and to put it into use by calculating and comparing the costs attributable to overweight for The Netherlands, Germany and Czech Republic. The tool uses a top-down and prevalence-based approach, consisting of five steps. Step one identifies overweight-related diseases and age- and gender-specific relative risks. Included diseases are ischemic heart disease, stroke, hypertension, type 2 diabetes mellitus, colorectal cancer, postmenopa...
Source: The European Journal of Health Economics - November 28, 2014 Category: Health Management Source Type: research

Drugs used to treat joint and muscle disease
Publication date: Available online 19 February 2015 Source:Anaesthesia & Intensive Care Medicine Author(s): David G. Lambert Joint disease: Arthritis can be simply broken into osteoarthritis and rheumatoid arthritis (RA). Osteoarthritis is treated with symptomatic pain relief and surgery. RA is a chronic autoimmune disease that causes inflammation of joints (leading to their destruction), tissues around joints and other organ systems. Treatment (for pain) of RA in the first instance is with non-steroidal anti-inflammatory drugs, with second-line treatment using disease-modifying antirheumatic drugs (DMARDs). DMAR...
Source: Anaesthesia and intensive care medicine - February 24, 2015 Category: Anesthesiology Source Type: research

People with gout have lower risk of Alzheimer’s disease
Conclusion This population-based study has found that people with gout had a 24% reduced risk of developing Alzheimer’s disease. It was a well-designed study, in that there were large numbers of people in each group and multiple potential confounding factors were taken into account. The validation of the study was also valuable in showing the expected lack of a link between osteoarthritis and Alzheimer’s disease. However, there are some limitations with this type of study, with a major one being that it cannot prove cause and effect. While some potential confounding factors were accounted for in the statistical analysi...
Source: NHS News Feed - March 5, 2015 Category: Consumer Health News Tags: Medical practice Neurology Older people Source Type: news

Disability and not osteoarthritis predicts cardiovascular disease: a prospective population-based cohort study
Conclusions In this large population-based study, participants with OA were not at increased risk of CVD. The close relation between disability and osteoarthritis may explain previous findings. Further studies are required in order to clarify whether OA patients need more intensive treatment of their cardiovascular risk factors.
Source: Annals of the Rheumatic Diseases - March 5, 2015 Category: Rheumatology Authors: Hoeven, T. A., Leening, M. J. G., Bindels, P. J., Castano-Betancourt, M., van Meurs, J. B., Franco, O. H., Kavousi, M., Hofman, A., Ikram, M. A., Witteman, J. C. M., Bierma-Zeinstra, S. M. Tags: Degenerative joint disease, Musculoskeletal syndromes, Osteoarthritis, Epidemiology Clinical and epidemiological research Source Type: research

Hip osteoarthritis and the risk of all‐cause and disease‐specific mortality in older women: Population‐based cohort study
Conclusion RHOA was associated with an increased risk of all‐cause and CVD mortality among older white women followed for 16 years. Dissemination of evidence‐based physical activity and self‐management interventions for hip OA in community and clinical settings can improve physical function and might also contribute to lower mortality. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - March 16, 2015 Category: Rheumatology Authors: Kamil E. Barbour, Li‐Yung Lui, Michael C. Nevitt, Louise B. Murphy, Charles G. Helmick, Kristina A. Theis, Marc C. Hochberg, Nancy E. Lane, Jennifer M. Hootman, Jane A. Cauley, Tags: Full Length Source Type: research

HyDRA: gene prioritization via hybrid distance-score rank aggregation
Summary: Gene prioritization refers to a family of computational techniques for inferring disease genes through a set of training genes and carefully chosen similarity criteria. Test genes are scored based on their average similarity to the training set, and the rankings of genes under various similarity criteria are aggregated via statistical methods. The contributions of our work are threefold: (i) first, based on the realization that there is no unique way to define an optimal aggregate for rankings, we investigate the predictive quality of a number of new aggregation methods and known fusion techniques from machine lea...
Source: Bioinformatics - April 2, 2015 Category: Bioinformatics Authors: Kim, M., Farnoud, F., Milenkovic, O. Tags: SYSTEMS BIOLOGY Source Type: research

Hip Osteoarthritis and the Risk of All‐Cause and Disease‐Specific Mortality in Older Women: A Population‐Based Cohort Study
ConclusionRHOA was associated with an increased risk of all‐cause and CVD mortality among older white women followed up for 16 years. Dissemination of evidence‐based physical activity and self‐management interventions for hip OA in community and clinical settings can improve physical function and might also contribute to lower mortality.
Source: Arthritis and Rheumatism - June 26, 2015 Category: Rheumatology Authors: Kamil E. Barbour, Li‐Yung Lui, Michael C. Nevitt, Louise B. Murphy, Charles G. Helmick, Kristina A. Theis, Marc C. Hochberg, Nancy E. Lane, Jennifer M. Hootman, Jane A. Cauley, Tags: Osteoarthritis Source Type: research