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Condition: Osteoarthritis

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Total 270 results found since Jan 2013.

Advancements of Prussian blue-based nanoplatforms in biomedical fields: Progress and perspectives
J Control Release. 2022 Oct 7:S0168-3659(22)00677-0. doi: 10.1016/j.jconrel.2022.10.007. Online ahead of print.ABSTRACTPrussian blue (PB) nanoparticles possess excellent physicochemical properties, including imaging features, robust photothermal conversion ability, catalytic activity, surface modifiability, effective drug loading, good stability, biocompatibility and biodegradability. With the advancement of nanotechnology, diverse PB-based nanoplatforms have been developed for biomedical applications. This review systematically summarized recent studies on PB-based nanoplatforms in the treatment of tumor (photothermal the...
Source: Atherosclerosis - October 10, 2022 Category: Cardiology Authors: Yanhui Wang Zonghao Liang Ziyang Liang Wenfeng Lv Min Chen Yi Zhao Source Type: research

Factors Associated With the Development of Tinnitus and With the Degree of Annoyance Caused by Newly Developed Tinnitus
Objectives: Tinnitus is highly prevalent, but only a few risk factors for developing tinnitus are known and little is known about factors associated with the degree of annoyance of new-onset tinnitus. Longitudinal analysis can reveal risk factors associated with the development of tinnitus and might lead to targeted prevention. The aim of this study is twofold. (1) To identify risk factors that are longitudinally associated with the odds of developing tinnitus 5 years later. (2) To identify factors that are cross-sectionally associated with tinnitus annoyance in adults with new-onset tinnitus. Methods: Baseline,...
Source: Ear and Hearing - October 28, 2022 Category: Audiology Tags: Research Article Source Type: research

Menopause and weight gain
Many women approaching the menopause will experience a number of symptoms, including vaginal dryness, hot flushes and a lack of sex drive. However another symptom that may arise as a result of the menopause is weight gain. Most commonly occurring around the hips and abdomen, this menopausal symptom for the majority of women is considered to be the least desirable. Although the exact factors that contribute to weight gain are not entirely understood, it is known that a decline in oestrogen levels, a loss of muscle tissue and lifestyle factors are part of the cause. Though it can be argued that a slight increase in weight i...
Source: The Hysterectomy Association - November 7, 2013 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health hormone replacement therapy oestrogen weight gain Source Type: news

Measuring the burden of comorbidity for ischaemic heart disease and four common non-communicable diseases in Iran, 1990-2017: a modelling study based on global burden of diseases data
Conclusion Of the four comorbidities studied, the highest burden was due to the coexistence of MDD with IHD. Our results highlight the importance of addressing the burden of comorbidities when studying the burden of IHD or any other non-communicable disease.
Source: BMJ Open - November 17, 2022 Category: General Medicine Authors: Mansourian, M., Ghasemi, K., Haghdoost, A., Kopec, J. A., Sarrafzadegan, N., Islam, S. M. S. Tags: Open access, Epidemiology Source Type: research

Determining the safety and effectiveness of Tai Chi: a critical overview of 210 systematic reviews of controlled clinical trials
ConclusionsThe findings suggest Tai Chi has multidimensional effects, including physical, psychological and quality of life benefits for a wide range of conditions, as well as multimorbidity. Clinically important benefits were most consistently reported for Parkinson ’s disease, falls risk, knee osteoarthritis, low back pain, cerebrovascular, and cardiovascular diseases including hypertension. For most conditions, higher-quality SRs with rigorous primary studies are required.Systematic review registrationPROSPERO CRD42021225708.
Source: Systematic Reviews - December 3, 2022 Category: International Medicine & Public Health Source Type: research

Channa striatus in inflammatory conditions: A systematic review
Channa striatus (CS), or snakehead murrel, is an obligate air-breathing freshwater fish. Besides its wound healing properties, CS has also been reported to exhibit anti-inflammatory effects in multiple studies. While there are anti-inflammatory medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), their long-term use is associated with an increased risk of peptic ulcers, acute renal failure, stroke, and myocardial infarction. Thus, it is essential to look at natural methods such as CS extract. While there is an abundant number of investigative studies on the inflammatory properties of CS, the quality of these ...
Source: Frontiers in Pharmacology - December 5, 2022 Category: Drugs & Pharmacology Source Type: research

Burden of disease of chronic pain in Ecuador
CONCLUSIONS: Chronic pain is an important source of burden of disease. It is comparable to other important causes such as headaches, stroke, diabetes and chronic obstructive pulmonary disease, among others. Low back pain, osteoarthritis and other musculoskeletal pain were the biggest contributors given their high prevalence.PMID:36946473 | DOI:10.1080/14737167.2023.2193689
Source: Expert Review of Pharmacoeconomics and Outcomes Research - March 22, 2023 Category: Health Management Authors: Pieralessandro Lasalvia Yaneth Gil-Rojas Diego Rosselli Source Type: research

NIH highlights PET imaging in study of rare bone disease
The U.S. National Institutes of Health (NIH) has highlighted a study featurin...Read more on AuntMinnie.comRelated Reading: NaF-PET shows bone formation in psoriatic arthritis patients PET/MRI provides new insights into knee osteoarthritis NaF-PET reveals aortic wall injuries NaF-PET scans reveal plaque -- and possible risk of stroke Can deep learning monitor lesions on F-18 NaF PET/CT?
Source: AuntMinnie.com Headlines - April 10, 2023 Category: Radiology Source Type: news

Controlling hypothalamic DNA methylation at the Pomc promoter does not regulate weight gain during the development of obesity
by Taylor McFadden, Natasha Gaito, Isabella Carucci, Everett Fletchall, Kayla Farrell, Timothy J. Jarome Obesity is a complex medical condition that is linked to various health complications such as infertility, stroke, and osteoarthritis. Understanding the neurobiology of obesity is crucial for responding to the etiology of this disease. The hypothalamus coordinates many integral activities such as hormone regulation and feed intake and numerous studies have observed altered hypothalamic gene regulation in obesity models. Previously, it was reported that the promoter region of the satiety gene,Pomc, has increased DNA met...
Source: PLoS One - April 10, 2023 Category: Biomedical Science Authors: Taylor McFadden Source Type: research

Metabolic syndrome and osteoarthritis: implications for the management of an increasingly common phenotype
Metabolic syndrome is an accumulation of three or more seemingly benign and relatively common conditions (central obesity, hypertension, raised triglycerides, low HDL-cholesterol, glucose intolerance) that, together, increase the risk of developing serious chronic disease.1 It is estimated that one-quarter of adults worldwide have metabolic syndrome2 — a concerning statistic considering that this population is five times more likely to develop diabetes, and two-to-three times more likely to develop heart disease, stroke, and certain cancers.
Source: Osteoarthritis and Cartilage - June 20, 2023 Category: Rheumatology Authors: Casey L Peiris, Adam G Culvenor Tags: Editorial Source Type: research

Menopause and weight gain
Many women approaching the menopause will experience a number of symptoms, including vaginal dryness, hot flushes and a lack of sex drive. However another symptom that may arise as a result of the menopause is weight gain. Most commonly occurring around the hips and abdomen, this menopausal symptom for the majority of women is considered to be the least desirable. Although the exact factors that contribute to weight gain are not entirely understood, it is known that a decline in oestrogen levels, a loss of muscle tissue and lifestyle factors are part of the cause. Though it can be argued that a slight increase in weight i...
Source: The Hysterectomy Association - November 7, 2013 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health hormone replacement therapy oestrogen weight gain Source Type: news