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Condition: Hypertension
Procedure: Cardiac Catheterization

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Total 178 results found since Jan 2013.

Right Ventricular Function Is Strongly Correlated With a Right Heart-Pulmonary System Rather Than With Right Ventricular Contractility
Background: RV function is a major determinant of clinical presentation in pulmonary hypertension. However, both of RVEF (MRI) and RVFAC (echocardiography) are highly load-dependent, and do not reflect RV contractility. Purpose: The aim of this study is to investigate the physiological correlates between RVFAC, RV contractility, RV afterload, and RV-PA coupling. Methods: Consecutive patients with PH who underwent RV catheterization and routine echocardiography were enrolled. RV afterload is estimated by arterial elastance (Ea), a ratio of end-systolic pressure to stroke volume.
Source: Journal of Cardiac Failure - September 20, 2017 Category: Cardiology Authors: Yoshihiro Dohi, Yasuki Kihara Source Type: research

Abstract P104: Oxygen Drastically Increases Cardiac Output Without Changing Mean Pulmonary Arterial Pressure in a Patient With Severe, Progressive Pulmonary Hypertension Session Title: Onsite Poster Competition I With Reception
Conclusion: Our patient had no significant change in mPAP facing oxygen-induced decrease in PVR. Instead, there was a marked increase in RV CO explainable only by an increase in RV SV facing decreased RV afterload, as HR decreased with oxygen. These findings are consistent with the patient’s class 1 exercise capacity despite having severe PH, indicating an ability to increase CO with activity and suggesting a positive response to medications and better prognosis. Our case shows the importance of assessing hemodynamic data in the workup and management of PH. We propose using TTE assessment of CO coupled with 100% oxygen a...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Dan Zheng, Thomas Roe Tags: Poster Abstract Presentations Source Type: research

Clinical Significance of Pulmonary Arterial Capacitance Calculated by Echocardiography in Patients With Advanced Heart Failure.
CONCLUSIONS: Decreased PAC as measured by echocardiography, indicating elevated PAWP and RV dysfunction, predicted poorer outcomes in patients with advanced HF. PMID: 28679970 [PubMed - as supplied by publisher]
Source: Circulation Journal - July 4, 2017 Category: Cardiology Authors: Saito Y, Ohtani T, Kioka H, Onishi T, Tsukamoto Y, Nakamoto K, Taniguchi T, Nakatani S, Hirayama A, Sakata Y Tags: Circ J Source Type: research

RVOT-VTI/PASP Is a Novel Noninvasive Parameter of Pulmonary Artery Compliance and Improves After Treatment with Pulmonary Hypertension-Specific Therapy
Pulmonary artery compliance (PAC) is an independent predictor of mortality in patients with pulmonary hypertension (PH). We have previously shown that the ratio of echocardiography derived right ventricular outflow tract velocity time integral (RVOT-VTI; an estimate of stroke volume) to pulmonary artery systolic pressure (PASP) correlates with PAC measured by right heart catheterization. We sought to determine whether PH-specific therapy improves PAC in patients with pulmonary arterial hypertension (PAH).
Source: The Journal of Heart and Lung Transplantation - March 25, 2017 Category: Transplant Surgery Authors: M.S. Tanna, A. Fox, G.S. Troutman, P.T. Bhattacharya, J.N. Menachem, F. Mao, E.Y. Birati, P.R. Forfia, A. Vaidya, J.A. Mazurek Source Type: research

Comorbidities and Complications in Nonagenarians Undergoing Coronary Angiography and Intervention.
Authors: Gayed M, Yadak N, Qamhia W, Daralammouri Y, Ohlow MA Abstract Elderly people represent the fastest growing portion of cardiovascular patients. We aimed to analyze the clinical presentation, risk factors, co-morbidities, complications, and mortality in patients 90 years or more who underwent coronary angiography and intervention.We retrospectively studied 108 (0.25% of 43,385) consecutive patients ≥ 90 years undergoing cardiac catheterization and/or intervention in a tertiary specialist hospital between 2003 and 2014.Most patients (68.5%) were introduced on an emergency basis, especially with acute corona...
Source: International Heart Journal - March 24, 2017 Category: Cardiology Tags: Int Heart J Source Type: research

Recurrent contrast ‐induced encephalopathy following coronary angiography
Contrast‐induced encephalopathy (CIE) is an acute and reversible neurological disturbance associated with the intra‐arterial administration of iodinated contrast medium during cardiac catheterisation. It may manifest with encephalopathy, motor and sensory disturbances; vision disturbances, including cortical blindness, ophthalmoplegia, aphasia; and seizures. Disruption of the blood–brain barrier and direct neuronal toxicity are believed to be implicated in the pathophysiology of the syndrome. Symptoms appear soon after contrast administration and resolve completely within 24–48 h. Risk factors may include hypertens...
Source: Internal Medicine Journal - February 14, 2017 Category: Internal Medicine Authors: Roberto Spina, Neil Simon, Romesh Markus, David W. M. Muller, Krishna Kathir Tags: Brief Communication Source Type: research

Contrast ‐induced encephalopathy following cardiac catheterization
ConclusionsCIE is an important clinical entity to consider in the differential diagnosis of stroke following cardiac catheterization. Given that prognosis is excellent with supportive management only, physicians should be aware of it, and consider it prior to initiating thrombolysis. © 2016 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - November 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Roberto Spina, Neil Simon, Romesh Markus, David WM Muller, Krishna Kathir Tags: Coronary Artery Disease Source Type: research

Response to treatment assessment in patients with PAH by MRI based computational modelling
Conclusion: The non-invasive proposed metrics have the potential to assess the response to PAH therapy, reducing the RHC interventions at follow-up.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Lungu, A., Hose, R., Capener, D., Kiely, D., Wild, J., Swift, A. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

Age is independently associated with pulmonary arterial compliance in health and in patients with pulmonary vascular disease
Discussion: Advancing age is independently associated with pulmonary arterial compliance in health and disease. In contrast to younger patients, pulmonary arterial compliance does not increase in response to PAH therapy in older patients.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Swift, A., Lungu, A., Capener, D., Hammerton, C., Rothman, A., Lawrie, A., Elliot, C., Condliffe, R., Kiely, D., Wild, J. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

MRI derived left atrial volume index predicts treatment response in patients with PAH
Conclusion: This study shows that in patients meeting the haemodynamic criteria for PAH, patients with an elevated LA volume had poor response to PAH therapy. Further work to better characterize this PAH phenotype and recognize the importance of comorbidities in predicting response to therapy is required.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Tubman, E., Sproson, T., Capener, D., Condliffe, R., Elliot, C., Charalampopolous, A., Kiely, D., Jim, W., Swift, A. Tags: 4.3 Pulmonary Circulation and Pulmonary Vascular Diseases Source Type: research

A Zero-Dimensional Model and Protocol for Simulating Patient-Specific Pulmonary Hemodynamics From Limited Clinical Data
The objective of this study was to develop and validate a 0D computational model, along with a numerical implementation protocol, of the RV –PA axis. Model results are qualitatively compared with published clinical data and quantitatively validated against right heart catheterization (RHC) for 115 pediatric PH patients. The RV–PA circuit is represented using a general elastance function for the RV and a three-element Windkessel init ial value problem for the PA. The circuit mathematically sits between two reservoirs of constant pressure, which represent the right and left atriums. We compared Pmax, Pmin, mPAP, cardiac ...
Source: Journal of Biomechanical Engineering - November 3, 2016 Category: Biomedical Engineering Source Type: research

Left ventricular deformation at rest predicts exercise ‐induced elevation in pulmonary artery wedge pressure in patients with unexplained dyspnoea
ConclusionLeft ventricular deformation at rest predicts exercise‐induced rise in PAWP among patients with dyspnoea and a preserved LVEF. A pattern of rest deformation characterized by worse LS and exaggerated CS is most strongly associated with exercise‐induced rise in PAWP.
Source: European Journal of Heart Failure - October 31, 2016 Category: Cardiology Authors: Tor Biering ‐Sørensen, Mário Santos, Jose Rivero, Shane D. McCullough, Erin West, Alexander R. Opotowsky, Aaron B. Waxman, David M. Systrom, Amil M. Shah Tags: Original Article Source Type: research

Factors relating to impaired stroke volume during the 6-minute walk test in patients with systemic sclerosis.
CONCLUSIONS: Impaired stroke volume in patients with systemic sclerosis was observed at rest and during exercise, and the factors relating to the cardiac response seemed to be pulmonary function and the extent of pulmonary hypertension. PMID: 27463117 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - July 28, 2016 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Prognostic value of right ventricular ejection/filling parameters in IPAH using cardiac magnetic resonance: A prospective pilot study
Conclusion CMR‐derived RV TPER and TPER/TCC can reflect RV early systolic function, and may be promising predictors for long‐term prognosis in IPAH patients.
Source: Respirology - July 22, 2016 Category: Respiratory Medicine Authors: Wen Li, Tao Yang, Yan Zhang, Qing Gu, Zhi ‐Hong Liu, Xin‐Hai Ni, Qin Luo, Chang‐Ming Xiong, Jian‐Guo He Tags: Original Article Source Type: research

Risk of stroke in first-ever acute urinary retention: A 10-year population-based study
Conclusion There was significant difference in the risk of stroke between patients with and without AUR. Preventive measures should be taken for patients with AUR, which may be associated with an increased risk of subsequent stroke. Large-scale population-based studies in other countries and regions are recommended.
Source: Urological Science - July 1, 2016 Category: Urology & Nephrology Source Type: research