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Assessment of rehabilitation following subarachnoid haemorrhage in China: findings from the Chinese Stroke Center Alliance
Rehabilitation improves functional recovery in subarachnoid hemorrhage (SAH) patients, and assessing patients for rehabilitation is the first step in this process. However, little is known about clinical pract...
Source: BMC Neurology - August 5, 2023 Category: Neurology Authors: Yi-Tong Chen, Mei-Ru Wu, Zi-Xiao Li, Hong-Qiu Gu, Qi Zhou, Dan-Dan Wang, Yong-Jun Wang and Xing-Quan  Zhao Tags: Research Source Type: research

China stroke surveillance report 2021
AbstractSince 2015, stroke has become the leading cause of death and disability in China, posing a significant threat to the health of its citizens as a major chronic non-communicable disease. According to the China Stroke High-risk Population Screening and Intervention Program, an estimated 17.8 million [95% confidence interval (CI) 17.6 –18.0 million] adults in China had experienced a stroke in 2020, with 3.4 million (95% CI 3.3–3.5 million) experiencing their first-ever stroke and another 2.3 million (95% CI 2.2–2.4 million) dying as a result. Additionally, approximately 12.5% (95% CI 12.4–12.5%) of stroke survi...
Source: Military Medical Research - July 19, 2023 Category: International Medicine & Public Health Source Type: research

Stroke burden and attributable risk factors in China, 1990 –2019
ConclusionThis study reinforced the findings of an increased stroke burden in China. Precise stroke prevention strategies are needed to reduce the disease burden of stroke.
Source: Frontiers in Neurology - May 24, 2023 Category: Neurology Source Type: research

Alpha-Asarone Ameliorates Neurological Dysfunction of Subarachnoid Hemorrhagic Rats in Both Acute and Recovery Phases via Regulating the CaMKII-Dependent Pathways
AbstractEarly brain injury (EBI) is the leading cause of poor prognosis for patients suffering from subarachnoid hemorrhage (SAH), particularly learning and memory deficits in the repair phase. A recent report has involved calcium/calmodulin-dependent protein kinase II (CaMKII) in the pathophysiological process underlying SAH-induced EBI. Alpha-asarone (ASA), a major compound isolated from the Chinese medicinal herbAcorus tatarinowii Schott, was proven to reduce secondary brain injury by decreasing CaMKII over-phosphorylation in rats ’ model of intracerebral hemorrhage in our previous report. However, the effect of ASA o...
Source: Translational Stroke Research - February 13, 2023 Category: Neurology Source Type: research

Naoxintong Capsule for Secondary Prevention of Ischemic Stroke: A Multicenter, Randomized, and Placebo-Controlled Trial
ConclusionThe combination of Naoxintong Capsule with standard care reduced the 2-year stroke recurrence rate in patients with ischemic stroke without increasing the risk of severe hemorrhage in high-risk patients. (Trial registration No. NCT02334969)
Source: Chinese Journal of Integrative Medicine - October 17, 2022 Category: Internal Medicine Source Type: research

The evolution of intracranial aneurysm research from 2012 to 2021: Global productivity and publication trends
ConclusionThe contribution made by different countries, institutions, journals, and authors for IA research over the past decade was demonstrated in the paper. The main topics include the choice of EVT or surgical clipping, particularly the application of flow diverter and associated complications, while themes such as the etiopathogenetic features of IA (e.g., inflammation and hemodynamics) deserve more attention.
Source: Frontiers in Neurology - September 28, 2022 Category: Neurology Source Type: research

Evaluating the impact of personalized rehabilitation nursing management in the perioperative nursing of patients with intracranial aneurysm: A protocol for systematic review and meta-analysis
Conclusion: Results of this research will synthesize the current data to determine whether or not tailored rehabilitation nursing treatment may enhance the surgical recovery of patients with IA.
Source: Medicine - July 15, 2022 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Diagnostic accuracy of major stroke types in Chinese adults: A clinical adjudication study involving 40,000 stroke cases
Lancet Reg Health West Pac. 2022 Mar 5;21:100415. doi: 10.1016/j.lanwpc.2022.100415. eCollection 2022 Apr.ABSTRACTBACKGROUND: Widespread use of brain imaging in suspected stroke cases in Chinese adults has prompted the need for clinical adjudication studies of stroke types. We conducted a clinical adjudication study to assess the reporting and diagnostic accuracy of major stroke types.METHODS: The prospective China Kadoorie Biobank recruited >512,000 adults (mean age 52 years, 59% women) from 10 urban and rural areas in China during 2004-2008, and recorded 45,859 first-ever incident stroke cases during an 11-year follow...
Source: Cancer Control - March 14, 2022 Category: Cancer & Oncology Authors: Iain Turnbull Robert Clarke Neil Wright Yu Guo Christina Kartsonaki Pei Pei Alex Hacker Canqing Yu Simon Gilbert Ling Yang Jinyi Zhou Sam Sansome Jun Lv Liming Li Zhengming Chen Yiping Chen Source Type: research

Age –Period–Cohort Analysis of Long Trend of Mortality for Stroke and Subtypes Attributed to High SBP in Chinese Adults
Stroke has been found as the leading cause of death in China, and high systolic blood pressure (SBP) has been indicated as a critical risk factor of stroke mortality. Accordingly, in this article, the aims were to investigate the long-term trends of mortality in terms of stroke and subtypes arising from high SBP stratified by age and gender among Chinese adults. The data of this article originated from the global burden of disease (GBD) study database. The age, period, and cohort effects were examined with the age–period–cohort model (APC). The age-standardized mortality of stroke attributed to high SBP in China has be...
Source: Frontiers in Neurology - March 9, 2022 Category: Neurology Source Type: research

Dysphagia screening and pneumonia after subarachnoid hemorrhage: Findings from the Chinese stroke center alliance
CONCLUSION: More than a quarter of patients with SAH did not have documented DS, while one-fifth developed pneumonia. DS performance was associated with a lower risk of pneumonia. Randomized controlled trials may be needed to determine the effectiveness of DS.PMID:35233938 | DOI:10.1111/cns.13822
Source: CNS Neuroscience and Therapeutics - March 2, 2022 Category: Neuroscience Authors: Mei-Ru Wu Yi-Tong Chen Zi-Xiao Li Hong-Qiu Gu Kai-Xuan Yang Yun-Yun Xiong Yong-Jun Wang Chun-Juan Wang Source Type: research

Trends in Incidence and Mortality of Stroke in China From 1990 to 2019
Conclusion: Although the incidence and mortality rates of stroke in China were decreased from 1990 to 2019, the number of incident cases and deaths nearly doubled. A sharp increase in the incidence rate of ischemic stroke was observed. A higher incidence rate of ischemic stroke in the women was also observed.
Source: Frontiers in Neurology - November 22, 2021 Category: Neurology Source Type: research

Interventions for altering blood pressure in people with acute subarachnoid haemorrhage
CONCLUSIONS: Based on the current evidence, there is a lack of information needed to confirm or reject minimally important intervention effects on patient-important outcomes for both induced hypertension and lowered blood pressure. There is an urgent need for trials assessing the effects of altering blood pressure in people with acute subarachnoid haemorrhage. Such trials should use the SPIRIT statement for their design and the CONSORT statement for their reporting. Moreover, such trials should use methods allowing for blinded altering of blood pressure and report on patient-important outcomes such as mortality, rebleeding...
Source: Cochrane Database of Systematic Reviews - November 17, 2021 Category: General Medicine Authors: Mathias Maagaard William K Karlsson Christian Ovesen Christian Gluud Janus C Jakobsen Source Type: research

Hospital management of major stroke types in Chinese adults: a population-based study of 20 000 hospitalised stroke cases
Conclusions Among IS cases, use of antiplatelet and lipid-lowering medications increased in recent years, but use of TCM still exceeded use of blood pressure-lowering treatment. In contrast, blood pressure-lowering treatment was widely used for ICH, but only half of all ICH cases used blood pressure-lowering treatment.
Source: BMJ Open - November 16, 2021 Category: General Medicine Authors: Qin, H., Turnbull, I., Chen, Y., Wright, N., Liu, L., Pei, P., Tang, W., Xiang, S., Guo, Y., Zhao, X., Clarke, R., Li, L., Wang, Y., Chen, Z., On behalf of The China Kadoorie Biobank Collaborative Group Tags: Open access, Epidemiology Source Type: research

Epidemiology of stroke in the last decade: a systematic review
CONCLUSION: There are few studies that analyse the incidence of CVD and even fewer that analyse its evolution. The overall median remains high, although the figures are heterogeneous across studies. Worldwide the trend is towards its decrease, and there are geographical areas, especially in Asia, with an alarming upward trend.PMID:34676530 | DOI:10.33588/rn.7309.2021138
Source: Revista de Neurologia - October 22, 2021 Category: Neurology Authors: F Purroy N Montal à Source Type: research

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