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Specialty: Cardiology
Condition: Hemorrhagic Stroke

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Total 1473 results found since Jan 2013.

Statin Use in ICH Linked to Lower Risk for Subsequent Stroke Statin Use in ICH Linked to Lower Risk for Subsequent Stroke
Observational data suggest that use of statins after intracerebral hemorrhage is linked to lower risk for recurrent stroke. Researchers call for a randomized trial of statins in these patients.Medscape Medical News
Source: Medscape Cardiology Headlines - August 30, 2023 Category: Cardiology Tags: Cardiology News Source Type: news

Intracranial haemorrhage in acute myocardial infarction: A rare but dramatic complication
The shift from thrombolysis to primary percutaneous coronary intervention (PCI) and the use of multidrug antithrombotic therapy in the management of acute myocardial infarction (AMI) have led to both a substantial improvement in outcomes and a reduction in bleeding complications [1,2]. In particular, in AMI, the rate of haemorrhagic stroke, the most dreaded haemorrhagic complication, decreased by 50% from 1998 to 2008 [1]. Despite its low incidence, intracranial haemorrhage (ICH) is often devastating, being associated with severe disability and high mortality rates.
Source: International Journal of Cardiology - August 29, 2023 Category: Cardiology Authors: Filippo Trombara, Nicola Cosentino, Giancarlo Marenzi Tags: Editorial Source Type: research

Direct Oral Anticoagulants versus Vitamin K Antagonists in Cirrhotic Patients with Atrial Fibrillation: Update of Systematic Review and Meta-Analysis
ConclusionDOACs are associated with more favorable safety outcomes and may be a feasible option of oral anticoagulant for individuals with atrial fibrillation and cirrhosis. Pending validation by randomized prospective studies, the findings of this study should be interpreted with caution.
Source: American Journal of Cardiovascular Drugs - August 28, 2023 Category: Cardiology Source Type: research

Multimodal investigation reveals the neuroprotective mechanism of Angong Niuhuang pill for intracerebral hemorrhage: Converging bioinformatics, network pharmacology, and experimental validation
CONCLUSION: The results of the study combined with virtual screening and experimental validation showed that ANP has an important contribution in protecting the brain from neuronal damage by regulating the pathways of inflammation and pyroptosis, laying the foundation and innovative ideas for future studies.PMID:37633621 | DOI:10.1016/j.jep.2023.117045
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Jiawei Zhou Tianlin Jiang Jiahua Wang Weilan Wu Xiaochun Duan Huiyun Jiang Zhiyun Jiao Xiaohong Wang Source Type: research

Plasma Trimethylamine- < em > N < /em > -Oxide and Incident Ischemic Stroke: The Cardiovascular Health Study and the Multi-Ethnic Study of Atherosclerosis
Conclusions Plasma TMAO levels are associated with incident ischemic stroke in a diverse population. Registration URL: https://www.clinicaltrials.gov. Unique identifier: NCT00005133.PMID:37581385 | DOI:10.1161/JAHA.122.029230
Source: Atherosclerosis - August 15, 2023 Category: Cardiology Authors: Rozenn N Lemaitre Paul N Jensen Zeneng Wang Amanda M Fretts Colleen M Sitlani Ina Nemet Nona Sotoodehnia Marcia C de Oliveira Otto Weifei Zhu Matt Budoff W T Longstreth Bruce M Psaty David S Siscovick Stanley L Hazen Dariush Mozaffarian Source Type: research

Comparative analysis of stenting for carotid web and atherosclerotic disease
CONCLUSION: Stenting for CaW was found to be technically simpler than CAD and not to confer increased risk of baroreceptor dysregulation. Intimal hyperplasia was uncommon in CaW cases.PMID:37563917 | DOI:10.1177/15910199231188856
Source: Atherosclerosis - August 11, 2023 Category: Cardiology Authors: Ehizele M Osehobo Raul G Nogueira Nilushi Karunamuni Sitara Koneru Achanti David Landzberg Qasem Al Shaer Jonathan A Grossberg Alhamza Al-Bayati Diogo C Haussen Source Type: research

Perioperative Brain Injury in Children with Aortic Arch Anomalies: A Retrospective Study of Risk Factors and Outcomes
This study examines the incidence, risk factors, and outcomes of perioperative brain injury in children undergoing aortic arch repair who had aortic arch anomalies. A total of 145 children with aortic arch anomalies in our center undergoing aortic arch repair between January 2014 and December 2022 were enrolled. There were 129 (89.0%) with coarctation of the aorta (COA) and 16 (9.7%) with interrupted aortic arch (IAA). Risk factor analysis of brain injuries was done using perioperative imaging and included symptoms of hemorrhagic stroke, arterial ischemic stroke, white matter injury, cerebral sinus venous thrombosis, and o...
Source: Pediatric Cardiology - August 10, 2023 Category: Cardiology Source Type: research

Lower-adherence direct oral anticoagulant use is associated with increased risk of thromboembolic events than warfarin
ConclusionsIn this large real-world study, low adherence DOAC was associated with higher risk of TE events as compared to high and low adherence warfarin.
Source: Journal of Interventional Cardiac Electrophysiology - August 9, 2023 Category: Cardiology Source Type: research

Safety and Efficacy of Prasugrel Administration in Emergent Endovascular Treatment for Intracranial Atherosclerotic Disease
CONCLUSION: Prasugrel administration was significantly associated with target vessel patency and good clinical outcome after emergent EVT for ICAD without increasing the symptomatic ICH rate. Prasugrel administration might be safe and effective to avoid reocclusion during and after emergent EVT for ICAD.PMID:37546344 | PMC:PMC10400910 | DOI:10.5797/jnet.oa.2023-0008
Source: Atherosclerosis - August 7, 2023 Category: Cardiology Authors: Katsunori Asai Masaaki Taniguchi Hajime Nakamura Akihiro Tateishi Naoki Irizato Hiroto Okubata Shogo Fukuya Kazuhiro Yoshimura Kazumi Yamamoto Haruhiko Kishima Akatsuki Wakayama Source Type: research

5-year Stroke Rates in Nonvalvular Atrial Fibrillation after Watchman compared to Direct Oral Anticoagulants
CONCLUSION: Even in a high-risk population, the WATCHMAN is comparable to DOAC therapy in the primary prevention of hemorrhagic strokes and may provide benefit in the rates of bleeding events, TIAs, and ischemic strokes.PMID:37541428 | DOI:10.1016/j.jjcc.2023.07.015
Source: Journal of Cardiology - August 4, 2023 Category: Cardiology Authors: Syed I Khalid Shyama Sathianathan Kyle B Thomson Laura Stone McGuire Mona C Soni Ankit I Mehta Source Type: research

Ticagrelor or Clopidogrel as Antiplatelet Agents in Patients with Chronic Kidney Disease and Cardiovascular Disease: A Meta-analysis
ConclusionsWhen compared with clopidogrel, even though ticagrelor was not associated with higher risk of adverse cardiovascular outcomes in these patients with CKD, it was associated with significantly higher BARC bleeding. Therefore, the safety outcomes of ticagrelor still require further evaluation in patients with CKD. Nevertheless, this hypothesis should only be confirmed with more powerful results that could usually only be achieved using large-scale randomized trials.
Source: American Journal of Cardiovascular Drugs - August 2, 2023 Category: Cardiology Source Type: research

Biliverdin reductase B is a plasma biomarker for intraplaque hemorrhage and a predictor of ischemic stroke in symptomatic carotid stenosis
Background and Aims: Intraplaque hemorrhage (IPH) is a hallmark of atherosclerotic plaque instability. Biliverdin reductase B (BLVRB) is enriched in plasma and plaques from patients with symptomatic carotid atherosclerosis and functionally associated with plaque IPH. We explored the biomarker potential of plasma BLVRB through 1) its correlation with IPH in carotid plaques assessed by magnetic resonance imaging (MRI) and with recurrent ischemic stroke; and 2) its use for monitoring pharmacotherapy targeting IPH in a preclinical setting.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: M. Chemaly, D. Marlevi, M.-J. Iglesias, M. Lengquist, M. Kronqvist, D. Bos, D.H.K. Van Dam-Nolen, A. Van Der Kolk, J. Hendrikse, M. Kassem, L. Matic, J. Odeberg, M.R. De Vries, M.E. Kooi, U. Hedin Source Type: research