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Specialty: Cardiology
Condition: Hemorrhagic Stroke

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Total 1473 results found since Jan 2013.

Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system
CONCLUSION: The metabolic profiles of the brains changed after HICH. Soyasaponin I alleviated HICH via inhibiting the RAAS and may serve as an effective drug for the treatment of HICH in the future.PMID:36809885 | DOI:10.1080/10641963.2023.2177667
Source: Clinical and Experimental Hypertension - February 22, 2023 Category: Cardiology Authors: Wei Li Shao-Guang Li Lan Li Li-Jian Yang Zeng-Shi Li Xi Li An-Yuan Ye Yang Xiong Yi Zhang Yuan-Yuan Xiong Source Type: research

Identifying patients at risk: multi ‐centre comparison of HeartMate 3 and HeartWare left ventricular assist devices
ConclusionsHM3 patients have a significantly better survival and a lower incidence of ischaemic strokes and pump thrombosis than HVAD patients. This survival difference persisted after 2  years of implantation. Additional research using post-operative variables is warranted to identify which HVAD patients need an upgrade to HM3 or expedited transplantation.
Source: ESC Heart Failure - February 17, 2023 Category: Cardiology Authors: Lieke Numan, Daniel Zimpfer, Osnat Itzhaki Ben Zadok, Emmeke Aarts, Michiel Morshuis, Sabina P.W. Guenther, Julia Riebandt, Dominik Wiedemann, Faiz Z. Ramjankhan, Anne ‐Marie Oppelaar, Tuvia Ben‐Gal, Binyamin Ben‐Avraham, Folkert W. Asse Tags: Original Article Source Type: research

Comparison of Safety and Efficacy after Emergency Stenting in Patients Exhibiting Intracranial Atherosclerotic Stenosis Associated with Large-vessel Occlusion with and without Intravenous Infusion of Tirofiban
CONCLUSION: The results of our study suggest that the application of tirofiban for rescue stenting after failed mechanical thrombectomy is safe.PMID:36797426 | DOI:10.1007/s00270-023-03372-7
Source: Atherosclerosis - February 16, 2023 Category: Cardiology Authors: Rana Garayzade Ansgar Berlis Stefan Schiele Hauke Schneider Michael Ertl Gernot M üller Christoph J Maurer Source Type: research

Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE
CONCLUSIONS: In patients with atherosclerotic cardiovascular disease, long-term achievement of lower LDL-C levels, down to <20 mg/dL (<0.5 mmol/L), was associated with a lower risk of cardiovascular outcomes with no significant safety concerns.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT01764633.PMID:36779348 | DOI:10.1161/CIRCULATIONAHA.122.063399
Source: Atherosclerosis - February 13, 2023 Category: Cardiology Authors: Prakriti Gaba Michelle L O'Donoghue Jeong-Gun Park Stephen D Wiviott Dan Atar Julia F Kuder KyungAh Im Sabina A Murphy Gaetano M De Ferrari Zbigniew A Gaciong Kalman Toth Ioanna Gouni-Berthold Jose Lopez-Miranda Fran çois Schiele Fran çois Mach Jose H F Source Type: research

Identifying vulnerable plaques: A 3D carotid plaque radiomics model based on HRMRI
CONCLUSIONS: HRMRI-based 3D carotid radiomics models can improve the precision of detecting vulnerable carotid plaques, consequently improving risk classification and clinical decision-making in patients with carotid stenosis.PMID:36779063 | PMC:PMC9908750 | DOI:10.3389/fneur.2023.1050899
Source: Atherosclerosis - February 13, 2023 Category: Cardiology Authors: Xun Zhang Zhaohui Hua Rui Chen Zhouyang Jiao Jintao Shan Chong Li Zhen Li Source Type: research

Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE
CONCLUSIONS: In patients with atherosclerotic cardiovascular disease, long-term achievement of lower LDL-C levels, down to <20 mg/dL (<0.5 mmol/L), was associated with a lower risk of cardiovascular outcomes with no significant safety concerns.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT01764633.PMID:36779348 | DOI:10.1161/CIRCULATIONAHA.122.063399
Source: Circulation - February 13, 2023 Category: Cardiology Authors: Prakriti Gaba Michelle L O'Donoghue Jeong-Gun Park Stephen D Wiviott Dan Atar Julia F Kuder KyungAh Im Sabina A Murphy Gaetano M De Ferrari Zbigniew A Gaciong Kalman Toth Ioanna Gouni-Berthold Jose Lopez-Miranda Fran çois Schiele Fran çois Mach Jose H F Source Type: research

Circulating macrophage colony-stimulating factor levels and stroke: A Mendelian randomization study
CONCLUSIONS: This study provides evidence that genetically predicted higher CSF1 levels was associated with higher risk of any ischemic stroke, LAS, and CES. Whether targeting CSF1 or its receptors can reduce the risk of ischemic stroke needs further study.PMID:36780760 | DOI:10.1016/j.jstrokecerebrovasdis.2023.107050
Source: Atherosclerosis - February 13, 2023 Category: Cardiology Authors: Liping Cao Dandan Liu Ville Karhunen Yi Ren Dan Ye Jie Gao Dipender Gill Mengmeng Wang Source Type: research

Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE
CONCLUSIONS: In patients with atherosclerotic cardiovascular disease, long-term achievement of lower LDL-C levels, down to <20 mg/dL (<0.5 mmol/L), was associated with a lower risk of cardiovascular outcomes with no significant safety concerns.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT01764633.PMID:36779348 | DOI:10.1161/CIRCULATIONAHA.122.063399
Source: Atherosclerosis - February 13, 2023 Category: Cardiology Authors: Prakriti Gaba Michelle L O'Donoghue Jeong-Gun Park Stephen D Wiviott Dan Atar Julia F Kuder KyungAh Im Sabina A Murphy Gaetano M De Ferrari Zbigniew A Gaciong Kalman Toth Ioanna Gouni-Berthold Jose Lopez-Miranda Fran çois Schiele Fran çois Mach Jose H F Source Type: research

Identifying vulnerable plaques: A 3D carotid plaque radiomics model based on HRMRI
CONCLUSIONS: HRMRI-based 3D carotid radiomics models can improve the precision of detecting vulnerable carotid plaques, consequently improving risk classification and clinical decision-making in patients with carotid stenosis.PMID:36779063 | PMC:PMC9908750 | DOI:10.3389/fneur.2023.1050899
Source: Atherosclerosis - February 13, 2023 Category: Cardiology Authors: Xun Zhang Zhaohui Hua Rui Chen Zhouyang Jiao Jintao Shan Chong Li Zhen Li Source Type: research

Endothelial Specific Deletion of Autotaxin Improves Stroke Outcomes
This study suggests that endothelial-specific ATX leads to increased LPA in the brain vasculature following ischemic-reperfusion and ultimately disrupts vascular permeability, resulting in adverse stroke outcomes.PMID:36766854 | DOI:10.3390/cells12030511
Source: Atherosclerosis - February 11, 2023 Category: Cardiology Authors: Susmita Bhattarai Utsab Subedi Shrivats Manikandan Sudha Sharma Papori Sharma Chloe Miller Md Shenuarin Bhuiyan Srivatsan Kidambi Vassilis Aidinis Hong Sun Sumitra Miriyala Manikandan Panchatcharam Source Type: research

Optimal use of antithrombotic agents in ischemic stroke with atrial fibrillation and large artery atherosclerosis
CONCLUSION: This study demonstrated that OAC monotherapy was associated with lower risks of composite outcome and death in patients at 1-year after ischemic stroke due to AF and atherosclerotic stenosis. In addition, the combination of an antiplatelet agent and OAC had a high risk of major bleeding.PMID:36748980 | DOI:10.1177/17474930231158211
Source: Atherosclerosis - February 7, 2023 Category: Cardiology Authors: Tae Jung Kim Ji Sung Lee Jae Sun Yoon Mi Sun Oh Ji-Woo Kim Soo-Hyun Park Keun-Hwa Jung Hye-Yeon Choi Hyun Young Kim Jee-Hyun Kwon Hahn Young Kim Kyung Yoon Eah Sang Won Han Hyung-Geun Oh Yong-Jae Kim Byoung-Soo Shin Chang Hun Kim Chi Kyung Kim Jong-Moo Pa Source Type: research

Effects of different etiologies of anterior circulation tandem lesions on short-term prognosis of acute ischemic stroke
CONCLUSION: The tandem lesions of anterior circulation caused by CAD tend to have a good functional prognosis in 3 months. The proportion of successful recanalization and surgical safety was similar between the two groups.PMID:36725823 | DOI:10.2174/1567202620666230201121411
Source: Atherosclerosis - February 1, 2023 Category: Cardiology Authors: Zhichao Huang Yingying Xu Shoujiang You Zhiliang Guo Jiaping Xu Yongjun Cao Guodong Xiao Chun-Feng Liu Source Type: research