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Specialty: Research
Condition: Hemorrhagic Stroke

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Total 217 results found since Jan 2013.

Association of ADH1B polymorphism and alcohol consumption with increased risk of intracerebral hemorrhagic stroke
Alcohol consumption is one of the modifiable risk factors for intracerebral hemorrhage, which accounts for approximately 10 –20% of all strokes worldwide. We evaluated the association of stroke with genetic pol...
Source: Journal of Translational Medicine - May 29, 2021 Category: Research Authors: Chun-Hsiang Lin, Oswald Ndi Nfor, Chien-Chang Ho, Shu-Yi Hsu, Disline Manli Tantoh, Yi-Chia Liaw, Mochly-Rosen Daria, Che-Hong Chen and Yung-Po Liaw Tags: Research Source Type: research

Aspiration Thrombectomy in Patients with Large Vessel Occlusion and Mild Stroke: A Single-Center Experience
CONCLUSIONS Immediate aspiration thrombectomy may be a safe and feasible first-line treatment option in patients suffering from mild stroke due to large vessel occlusion in the anterior and posterior circulation.PMID:34016941 | DOI:10.12659/MSM.930014
Source: Medical Science Monitor - May 21, 2021 Category: Research Authors: Jozef Haring Miroslav Mako J án Haršány Georgi Krastev Mat úš Hoferica Andrej Klepanec Source Type: research

The Natural History and Reperfusion Therapy Outcomes of Acute Ischemic Stroke due to Isolated M2 Occlusions
CONCLUSIONS: For acute, isolated M2 occlusions, EVT could dramatically and rapidly improve neurological deficits with high safety and effectiveness. These changes were observed at 24 hours after treatment and were maintained over the long term.PMID:33997031 | PMC:PMC8096556 | DOI:10.1155/2021/6626604
Source: Biomed Res - May 17, 2021 Category: Research Authors: Hongmin Gong Libo Zhao Ge Tang Yu Chen Deyu Yang Shudong Liu Source Type: research

Neurologic Manifestations of COVID-19
Adv Exp Med Biol. 2021;1318:343-353. doi: 10.1007/978-3-030-63761-3_20.ABSTRACTNeurological manifestations of novel coronavirus disease (COVID-19) are reported to occur in as much as 37% of the affected patients. These manifestations range from headache and dizziness to altered mental status and consciousness, anosmia, ageusia, sensory disturbances, and stroke. The mechanisms by which the neurological symptoms arise are not yet determined but may either proceed as an indirect consequence of systemic hyperinflammation or result from the direct invasion of the virus to neural and glial cells. The neural invasion can explain ...
Source: Advances in Experimental Medicine and Biology - May 11, 2021 Category: Research Authors: Farnaz Delavari Farnaz Najmi Varzaneh Nima Rezaei Source Type: research

Advances in the Development of Biomarkers for Poststroke Epilepsy
Biomed Res Int. 2021 Apr 17;2021:5567046. doi: 10.1155/2021/5567046. eCollection 2021.ABSTRACTStroke is the main cause of acquired epilepsy in elderly people. Poststroke epilepsy (PSE) not only affects functional recovery after stroke but also brings considerable social consequences. While some factors such as cortical involvement, hemorrhagic transformation, and stroke severity are associated with increased seizure risk, so far that remains controversial. In recent years, there are an increasing number of studies on potential biomarkers of PSE as tools for diagnosing and predicting epileptic seizures. Biomarkers such as i...
Source: Biomed Res - May 7, 2021 Category: Research Authors: Mengke Liang Liren Zhang Zhi Geng Source Type: research

COVID-19-Associated Acute Brain Dysfunction Related to Sepsis
J Clin Med Res. 2021 Feb;13(2):82-91. doi: 10.14740/jocmr4437. Epub 2021 Feb 25.ABSTRACTIn global term, as of November 30, 2020, over 30 million people has been infected by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and more than 10,000,000 of them died of acute organ failure. Our reviews have shown that coronavirus disease 2019 (COVID-19) patients with pneumonia and acute respiratory distress syndrome (ARDS) have life-threatening acute brain dysfunction (ABD), ranging from altered mental status/delirium to stupor/coma. Altered mental status/delirium was the most common manifestation of ABD cause...
Source: Clin Med Res - March 22, 2021 Category: Research Authors: Dao Ming Tong Ye Ting Zhou Yuan Wei Wang Source Type: research

Mini Craniotomy in the Management of Supratentorial Spontaneous Intracranial Hemorrhage: A Single-Center Outcome of the Minimally Invasive Treatment
Adv Exp Med Biol. 2021 Mar 14. doi: 10.1007/5584_2021_632. Online ahead of print.ABSTRACTHemorrhagic stroke accounts for a significant proportion of mortality and confers a poor quality of life with high dependency among survivors. Surgical evacuation of hematoma has the advantage of rapidly controlling the increased intracranial pressure, halting the ongoing herniation syndrome, and mitigating the secondary cascades of events mediated by the inflammatory and blood degradation products. The advantage is hindered by the concurrent insult to the healthy brain tissue while passing through the normal brain tissue. Therefore, m...
Source: Advances in Experimental Medicine and Biology - March 13, 2021 Category: Research Authors: Binod Bhattarai Aliza Bajracharya Suja Gurung Sweta Giri Sashi Bhusan Sah Sunil Munakomi Source Type: research

Effectiveness and Safety of Non-Vitamin K Antagonist Oral Anticoagulants in Asian Patients with Atrial Fibrillation and Valvular Heart Disease.
CONCLUSIONS: NOACs had a comparable risk of ischemic stroke and bleeding in patients with AF and VHD, and reduced the risk of venous thromboembolism, intracranial hemorrhage, and mortality, compared to warfarin. Therefore, NOAC is an effective and safe alternative to warfarin in these patients. PMID: 33538623 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - February 6, 2021 Category: Research Tags: Curr Med Res Opin Source Type: research

N-Methyl-D-Aspartate Receptor Signaling-Protein Kinases Crosstalk in Cerebral Ischemia.
Authors: Engin A, Engin AB Abstract Although stroke is very often the cause of death worldwide, the burden of ischemic and hemorrhagic stroke varies between regions and over time regarding differences in prognosis, prevalence of risk factors, and treatment strategies. Excitotoxicity, oxidative stress, dysfunction of the blood-brain barrier, neuroinflammation, and lysosomal membrane permeabilization, sequentially lead to the progressive death of neurons. In this process, protein kinases-related checkpoints tightly regulate N-methyl-D-aspartate (NMDA) receptor signaling pathways. One of the major hallmarks of cerebra...
Source: Advances in Experimental Medicine and Biology - February 6, 2021 Category: Research Tags: Adv Exp Med Biol Source Type: research