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Condition: Hemorrhagic Stroke

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Total 217 results found since Jan 2013.

Radioimaging and Demographic Profiles of Patients with Spontaneous Intracerebral Hemorrhage: A Need for the Pragmatic Referral System
Adv Exp Med Biol. 2021 Nov 14. doi: 10.1007/5584_2021_662. Online ahead of print.ABSTRACTReferring patients with severe medical conditions, like brain stroke, from small or rural hospitals to tertiary care centers is often overexploited leading to a kind of defensive medicine. The issue of a patient referral system remains unaddressed in Nepal. In this article, we investigated the legitimacy of referring patients with spontaneous intracranial hemorrhage (ICH) from country peripheral hospitals to the leading tertiary neurological center in Nepal. We found that 81 out of the 130 ICH patients reviewed in the study were referr...
Source: Advances in Experimental Medicine and Biology - November 13, 2021 Category: Research Authors: Sunil Munakomi Source Type: research

Disorder Genes Regulate the Progression of Ischemic Stroke through the NF- < em > κ < /em > B Signaling Pathway
Biomed Res Int. 2021 Oct 27;2021:2464269. doi: 10.1155/2021/2464269. eCollection 2021.ABSTRACTStroke is an acute cerebrovascular disease, including ischemic and hemorrhagic stroke. Stroke is the second leading cause of death after ischemic heart disease, which accounts for 9% of the global death toll. To explore the molecular mechanisms of the effects of the dysregulated factors, in the GEO database, we obtained transcriptome data from 24 h/72 h of mice with ischemic stroke and 24 h/72 h of normal mice. We then performed differential gene analysis, coexpression analysis, enrichment analysis, and regulator prediction bioinf...
Source: Biomed Res - November 8, 2021 Category: Research Authors: Wei Wei Wenqiang Xin Yufeng Tang Zhonglun Chen Yue Heng Mingjun Pu Bufan Yang Jiacai Zuo Jingfeng Duan Source Type: research

Combination anticoagulant or P2Y12 inhibitor with low-dose aspirin versus low-dose aspirin alone in patients at risk or with documented coronary and/or peripheral artery disease
CONCLUSIONS: Compared to clopidogrel + low dose aspirin, the use of rivaroxaban 2.5 mg twice daily + low dose aspirin reduced the risk of MACE, CV death and stroke including ischemic stroke in patients with or at high risk for chronic CAD and/or PAD. These benefits of rivaroxaban 2.5 mg twice daily + low dose aspirin compared to clopidogrel + low-dose aspirin appear to be achieved without significantly increasing patients' risk of moderate-to-severe including ICH or fatal bleeding.PMID:34641745 | DOI:10.1080/03007995.2021.1991294
Source: Current Medical Research and Opinion - October 13, 2021 Category: Research Authors: Craig I Coleman Akshay A Kharat Brahim Bookhart William L Baker Source Type: research

The burden of undertreatment and non-treatment among patients with non-valvular atrial fibrillation and elevated stroke risk: a systematic review
CONCLUSIONS: Rates of nontreatment and undertreatment among NVAF patients remain high and are associated with preventable cardiovascular events and death. Strategies to increase rates of treatment may improve clinical outcomes.PMID:34632887 | DOI:10.1080/03007995.2021.1982684
Source: Current Medical Research and Opinion - October 11, 2021 Category: Research Authors: Matthew Sussman Geoffrey D Barnes Jennifer D Guo Charles Y Tao John A Gillespie Mauricio Ferri Nicholas Adair Matthew S Cato Ilnaz Shirkhorshidian Manuela Di Fusco Source Type: research

Pyridoxal Isonicotinoyl Hydrazone Improves Neurological Recovery by Attenuating Ferroptosis and Inflammation in Cerebral Hemorrhagic Mice
Biomed Res Int. 2021 Sep 8;2021:9916328. doi: 10.1155/2021/9916328. eCollection 2021.ABSTRACTFerroptosis and inflammation induced by cerebral hemorrhage result in an excessive inflammatory response and irreversible neuronal injury. Alleviating ferroptosis might be an effective way to prevent neuroinflammatory injury and promote neural functional recovery. Pyridoxal isonicotinoyl hydrazine (PIH), a lipophilic iron-chelating agent, has been reported to reduce excess iron-induced cytotoxicity. However, whether PIH could ameliorate the effects of hemorrhagic stroke is not completely understood. In the present study, the preven...
Source: Biomed Res - September 20, 2021 Category: Research Authors: Hengli Zhang Min Wen Jiayu Chen Chaojie Yao Xiao Lin Zhongxiao Lin Junnan Ru Qichuan Zhuge Su Yang Source Type: research

Neurological Presentations of COVID-19: Characteristic Features in a Case Series of Hospitalized Patients from Abu Dhabi, UAE
CONCLUSION: COVID-19 patients who present with neurological involvement have a higher risk of mortality which is aggravated by older age and higher inflammatory markers. The type of neurological pathology does not seem to influence the risk of mortality.PMID:34423037 | PMC:PMC8376468 | DOI:10.1155/2021/5822259
Source: Biomed Res - August 23, 2021 Category: Research Authors: Asma Deeb Palat Chirakkara Kumar Nida Sakrani Ravi Kumar Trehan Vijay Ram Papinenei Source Type: research

Effect of holistic rehabilitation nursing on postoperative neurological function recovery and limb function improvement in patients with intraintracerebral hemorrhage
CONCLUSION: Holistic rehabilitation nursing intervention is more conducive to the recovery of postoperative neurological function and limb function improvement in patients with ICH, and meanwhile, it can alleviate the adverse psychological mood of patients and significantly improve their activities of daily living after operation.PMID:34306490 | PMC:PMC8290736
Source: American Journal of Translational Research - July 26, 2021 Category: Research Authors: Guanlun Zheng Xiaoqin Cai Rong Zhu Lanjuan Yang Tianhu Liu Source Type: research