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Condition: Hemorrhagic Stroke

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Total 217 results found since Jan 2013.

Applications for Electrical Impedance Tomography (EIT) and Electrical Properties of the Human Body.
In conclusion, Electrical Impedance Tomography is a promising method for the development of noninvasive diagnostic medicine, since it is able to provide imaging of the interior of the human body in real time without causing harm or putting the human body in risk. PMID: 28971420 [PubMed - in process]
Source: Advances in Experimental Medicine and Biology - October 4, 2017 Category: Research Tags: Adv Exp Med Biol Source Type: research

Outcomes associated with warfarin time in therapeutic range among US veterans with nonvalvular atrial fibrillation.
CONCLUSIONS: The observed quality of warfarin control in VA EMR suggests room for improvement given the association with elevated risk of adverse clinical outcomes. PMID: 28945114 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - September 27, 2017 Category: Research Tags: Curr Med Res Opin Source Type: research

Mystery of Retinal Vein Occlusion: Vasoactivity of the Vein and Possible Involvement of Endothelin-1.
Abstract Retinal vein occlusion (RVO) is a common vascular disease of retina; however, the pathomechanism leading to RVO is not yet clear. In general, increasing age, hypertension, arteriosclerosis, diabetes mellitus, dyslipidemia, cardiovascular disorder, and cerebral stroke are systemic risk factors of RVO. However, RVO often occur in the unilateral eye and sometimes develop in young subjects who have no arteriosclerosis. In addition, RVO show different variations on the degrees of severity; some RVO are resolved without any treatment and others develop vision-threatening complications such as macular edema, com...
Source: Biomed Res - September 15, 2017 Category: Research Authors: Kida T Tags: Biomed Res Int Source Type: research

No Awakening in Supratentorial Intracerebral Hemorrhage Is Potentially Caused by Sepsis-Associated Encephalopathy.
CONCLUSIONS NA in sICH patients with coma is potentially caused by secondary SAE. PMID: 28900072 [PubMed - in process]
Source: Medical Science Monitor - September 15, 2017 Category: Research Tags: Med Sci Monit Source Type: research

Cost-effectiveness analysis of dabigatran versus rivaroxaban for stroke prevention in patients with non-valvular atrial fibrillation using real-world evidence in elderly US Medicare beneficiaries.
CONCLUSIONS: In this study using US Medicare real-world data, dabigatran was found to dominate rivaroxaban. The analyses were limited by the short follow-up period of the real-world data and results may not be generalizable to other patient populations. PMID: 28862479 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - September 3, 2017 Category: Research Tags: Curr Med Res Opin Source Type: research

Effects of Mannitol 20% on Outcomes in Nontraumatic Intracerebral Hemorrhage.
CONCLUSIONS: Mannitol injection was not effective in reducing hemorrhage size, and its use is not recommended, also, further studies in this field have been proposed. PMID: 28706883 [PubMed]
Source: Biomed Res - July 16, 2017 Category: Research Authors: Aminmansour B, Tabesh H, Rezvani M, Poorjafari H Tags: Adv Biomed Res Source Type: research

Current Status and Future Perspective of Stenting for Symptomatic Intracranial Atherosclerotic Disease: A Meta-Analysis.
Abstract The aim of this study was to evaluate the safety and effectiveness of percutaneous transluminal angioplasty and stenting (PTAS) for intracranial atherosclerotic disease (ICAD) by conducting a meta-analysis. Two independent observers searched PubMed, EMBASE, and Cochrane Library for relevant studies up to 31 December 2016. A meta-analysis was conducted using Review Manager 5.3. Three studies involving 581 cases were included. The meta-analysis indicated that any stroke (RR = 3.13; 95% CI: 1.80-5.42), ischemic stroke (RR = 2.15; 95% CI: 1.19-3.89), and intracranial hemorrhage (RR = 14.71; 95% CI: 1.96-110.4...
Source: Biomed Res - July 14, 2017 Category: Research Authors: Li ZH, Zhou ZH, Zhu XJ, Liu W, Chen YW, Chen ZY, Liu ZJ Tags: Biomed Res Int Source Type: research

White Matter Injury and Recovery after Hypertensive Intracerebral Hemorrhage.
Abstract Hypertensive intracerebral hemorrhage (ICH) could very probably trigger white matter injury in patients. Through the continuous study of white matter injury after hypertensive ICH, we achieve a more profound understanding of the pathophysiological mechanism of its occurrence and development. At the same time, we found a series of drugs and treatment methods for the white matter repair. In the current reality, the research paradigm of white matter injury after hypertensive ICH is relatively obsolete or incomplete, and there are still lots of deficiencies in the research. In the face of the profound changes...
Source: Biomed Res - July 7, 2017 Category: Research Authors: Zuo S, Pan P, Li Q, Chen Y, Feng H Tags: Biomed Res Int Source Type: research

Intravenous Thrombolysis in Acute Ischemic Stroke with Active Cancer.
In conclusion, ischemic stroke patients with active cancer, especially those with a cryptogenic mechanism, showed poor clinical outcomes after use of IV t-PA. PMID: 28660209 [PubMed - in process]
Source: Biomed Res - July 1, 2017 Category: Research Authors: Nam KW, Kim CK, Kim TJ, An SJ, Oh K, Ko SB, Yoon BW Tags: Biomed Res Int Source Type: research

Treatment of Cervical Artery Dissection: Antithrombotics, Thrombolysis, and Endovascular Therapy.
Abstract Cervical artery dissection (CAD) is an important cause of stroke for young patients, accounting for 5-22% of strokes in patients <45 years of age, which presents not only a great burden to the stroke victims but also a financial burden to the family and society. Because CAD can lead to different clinical lesions, including neuropathy, acute ischemic stroke, and subarachnoid hemorrhage, and is an arterial dissection with a self-healing tendency, the treatment options depend on the clinical manifestations. The main purpose of the treatment is to control CAD-induced neuronal damage and to restore blood fl...
Source: Biomed Res - June 14, 2017 Category: Research Authors: Peng J, Liu Z, Luo C, Chen L, Hou X, Xiao L, Zhou Z Tags: Biomed Res Int Source Type: research

α7 Nicotinic Acetylcholine Receptor Stimulation Attenuates Neuroinflammation through JAK2-STAT3 Activation in Murine Models of Intracerebral Hemorrhage.
This study aimed to evaluate whether α7 nicotinic acetylcholine receptor (α7nAChR) stimulation ameliorates neuroinflammation after ICH. Male CD-1 mice and Sprague-Dawley were subjected to intracerebral injection of autologous blood or bacterial collagenase. ICH animals received either α7nAChR agonist PHA-543613 alone or combined with α7nAChR antagonist methyllycaconitine (MLA) or Janus kinase 2 (JAK2) antagonist AG490. Neurobehavioral deficits were evaluated at 24 hours, 72 hours, and 10 weeks after ICH induction. Perihematomal expressions of JAK2, signal transducer and activator of transcription 3 (STAT3), tumor necro...
Source: Biomed Res - May 24, 2017 Category: Research Authors: Krafft PR, McBride D, Rolland WB, Lekic T, Flores JJ, Zhang JH Tags: Biomed Res Int Source Type: research

TRPC Channels and Stroke.
Authors: Huang J Abstract TRPC channels play important roles in neuronal death/survival in ischemic stroke, vasospasm in hemorrhagic stroke, thrombin-induced astrocyte pathological changes, and also in the initiation of stroke by affecting blood pressure and atherogenesis. TRPCs' unique channel characters and downstream pathways make them possible new targets for stroke therapy. TRPC proteins have different functions in different cell types. Considering TRPCs' extensive distribution in various tissues and cell types, drugs targeting them could induce more complicated effects. More specific agonists/antagonists and ...
Source: Advances in Experimental Medicine and Biology - May 17, 2017 Category: Research Tags: Adv Exp Med Biol Source Type: research

Effect of Admission Hyperglycemia on 6-Month Functional Outcome in Patients with Spontaneous Cerebellar Hemorrhage.
CONCLUSIONS To the best of our knowledge, this is the first study focusing on the relationship between hyperglycemia and long-term functional outcome after CH. The study combined with previous pertinent reports definitely indicates the poor effect of hyperglycemia on both supra- and infratentorial ICH independent of hemorrhage site. Therefore, further controlled trials are urgently needed to evaluate the benefits of glucose-lowing treatment. PMID: 28273059 [PubMed - in process]
Source: Medical Science Monitor - March 9, 2017 Category: Research Tags: Med Sci Monit Source Type: research

Characteristics of Hemorrhagic Stroke following Spine and Joint Surgeries.
Abstract Hemorrhagic stroke can occur after spine and joint surgeries such as laminectomy, lumbar spinal fusion, tumor resection, and total joint arthroplasty. Although this kind of stroke rarely happens, it may cause severe consequences and high mortality rates. Typical clinical symptoms of hemorrhagic stroke after spine and joint surgeries include headache, vomiting, consciousness disturbance, and mental disorders. It can happen several hours after surgeries. Most bleeding sites are located in cerebellar hemisphere and temporal lobe. A cerebrospinal fluid (CSF) leakage caused by surgeries may be the key to intra...
Source: Biomed Res - February 7, 2017 Category: Research Authors: Yang F, Zhao J, Xu H Tags: Biomed Res Int Source Type: research

Intracerebral and Intravenous Transplantation Represents a Favorable Approach for Application of Human Umbilical Cord Mesenchymal Stromal Cells in Intracerebral Hemorrhage Rats.
CONCLUSIONS Both intracerebral and intravenous administration of UC-MSCs could have a favorable effect on recovery of neurological function in ICH rats, although the fundamental mechanisms may be different between the two groups. Our data suggest that intravenous implantation of UC-MSCs could serve as a favorable approach for cell-based therapy in central nervous system (CNS) diseases according to clinical needs. PMID: 27703134 [PubMed - in process]
Source: Medical Science Monitor - October 7, 2016 Category: Research Tags: Med Sci Monit Source Type: research