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Specialty: Neurology
Condition: Hemorrhagic Stroke
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Total 7056 results found since Jan 2013.
Neuroanatomical Correlates of Cognitive Impairment following Basal Ganglia-Thalamic Post-Hemorrhagic Stroke: Uncovering Network-Wide Alterations in Hemispheric Gray Matter Asymmetry
In conclusion, PhSCI patients exhibited network-wide cortical GM losses, distal to subcortical hemorrhagic lesions, and hemisphere asymmetry changes. These changes appear to predict rTMS-related cognitive improvements, suggesting that even subcortical focal lesions can lead to alterations in distal cortical neuroanatomical architecture. Our preliminary findings provide new insights into the neuroanatomical basis of PhSCI.PMID:37652090 | DOI:10.1016/j.brainres.2023.148559
Source: Brain Research - August 31, 2023 Category: Neurology Authors: Huan Wang Minhua Yu Jinxia Ren Xiaoli Zhong Dan Xu Lei Gao Haibo Xu Source Type: research
20 kDa isoform of connexin-43 augments spatial reorganization of the brain endothelial junctional complex and lesion leakage in cerebral cavernous malformation type-3
This study highlights generation of potential defects at the CCM3-affected brain endothelial barrier which may underlie prolonged vascular leakiness.PMID:37652184 | DOI:10.1016/j.nbd.2023.106277
Source: Neurobiology of Disease - August 31, 2023 Category: Neurology Authors: Chelsea M Phillips Allison M Johnson Svetlana M Stamatovic Richard F Keep Anuska V Andjelkovic Source Type: research
Factors associated with hemorrhagic transformation after endovascular treatment despite early recanalization
To identify new factors associated with hemorrhagic transformation (HT) despite early recanalization in patients with acute ischemic stroke treated with mechanical thrombectomy.
Source: Journal of the Neurological Sciences - August 30, 2023 Category: Neurology Authors: Antonio Ciacciarelli, Agostino Tessitore, Giulia Fiume, Carmelo Tiberio Curr ò, Alessandra Coglitore, Anna Gardin, Fabrizio Giammello, Francesco Grillo, Mirta Longo, Enrico Mormina, Concetto Fabio Vecchio, Davide Vicari, Rosa Fortunata Musolino, Antonio Source Type: research
Prior Thrombectomy Does Not Affect the Surgical Complication Rate of Decompressive Hemicraniectomy in Patients with Malignant Ischemic Stroke
ConclusionsA prior mechanical recanalization with possibly associated systemic thrombolysis does not affect the early surgical complication rate and the functional outcome after decompressive hemicraniectomy for malignant ischemic stroke. Patient characteristics have not changed significantly since the introduction of mechanical recanalization; therefore, the results from former large randomized controlled trials are still valid in the modern era of stroke care.
Source: Neurocritical Care - August 28, 2023 Category: Neurology Source Type: research
Cortical superficial siderosis is associated with reactive astrogliosis in cerebral amyloid angiopathy
Cortical superficial siderosis (cSS) has recently emerged as one of the most important predictors of symptomatic intracerebral hemorrhage and is a risk factor for post-stroke dementia in cerebral amyloid angio...
Source: Journal of Neuroinflammation - August 27, 2023 Category: Neurology Authors: Corinne A. Auger, Valentina Perosa, Steven M. Greenberg, Susanne J. van Veluw and Mariel G. Kozberg Tags: Research Source Type: research
Endovascular Treatment and Peri-interventional Management of Ruptured Cerebrovascular Lesions During Pregnancy
ConclusionEndovascular treatment of ruptured cerebrovascular malformations during pregnancy is safe and feasible regarding both aspects, the maternal and fetal outcomes. Still, a stronger knowledge base is needed to correctly approach future cases of intracranial hemorrhage in the pregnant population.
Source: Clinical Neuroradiology - August 24, 2023 Category: Neurology Source Type: research
Initial experience with minimally invasive endoscopic evacuation of intracerebral hemorrhage in the setting of radiographic herniation
Spontaneous intracerebral hemorrhage (ICH) can rapidly result in cerebral herniation, leading to poor neurologic outcomes or mortality. To date, neither decompressive hemicraniectomy (DH) nor hematoma evacuation have been conclusively shown to improve outcomes for comatose ICH patients presenting with cerebral herniation, with these patients largely excluded from clinical trials. Here we present the outcomes of a series of patients presenting with ICH and radiographic herniation who underwent emergent minimally invasive (MIS) ICH evacuation.
Source: Journal of Stroke and Cerebrovascular Diseases - August 23, 2023 Category: Neurology Authors: Muhammad Ali, Georgios A. Maragkos, Kurt A. Yaeger, Alexander J. Schupper, Trevor A. Hardigan, Vikram Vasan, Braxton R. Schuldt, Ian C. Odland, Margaret Downes, Jonathan Dullea, Luis C. Ascanio, Zachary S. Troiani, Nicki Mohammadi, Jacques Lara-Reyna, Rob Source Type: research
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Hospital Course, Confounders, and Medications
This article outlines the process of the development of common data elements for hospital course, confounders, and medications to streamline definitions and variables to collect for clinical studies of DoC.
Source: Neurocritical Care - August 23, 2023 Category: Neurology Source Type: research
Amantadine for NeuroenhaNcement in acutE patients Study - a protocol for a prospective pilot proof of concept phase IIb study in intensive and intermediate care unit patients (ANNES)
Persisting coma is a common complication in (neuro)intensive care in neurological disease such as acute ischemic stroke, intracerebral hemorrhage or subarachnoid hemorrhage. Amantadine acts as a nicotinic rece...
Source: BMC Neurology - August 22, 2023 Category: Neurology Authors: Anna Hofmann, Corinna Blum, Constanze Single, Kamal Adeyemi, Patricia Schwarz, Vasileios Siokas, Tim W. Rattay, Helene A. H äberle, Reimer Riessen, Bettina Brendel, Iris Haug, Ruth Bösel, Manola Zago, Peter Martus, Ulf Ziemann, Annerose Mengel & hellip; Tags: Study Protocol Source Type: research
Bypassing Closest Stroke Center for Intracerebral Hemorrhage
Prehospital stroke triage protocols focus on enabling rapid access to 2 proven time-sensitive short-term treatments: intravenous thrombolysis for all eligible patients with disabling acute ischemic stroke and endovascular therapy (EVT) for select patients with acute ischemic stroke from large vessel occlusion (LVO). As EVT is a particularly powerful treatment with an estimated number needed to treat of 2 to 3, prehospital screening tools and protocols have been developed that prioritize identifying potential patients with LVO in the field and preferentially transporting them to EVT-capable centers, even if this means bypas...
Source: JAMA Neurology - August 21, 2023 Category: Neurology Source Type: research
Effect of Bypassing the Closest Stroke Center in Patients with Intracerebral Hemorrhage
This prespecified secondary analysis of a randomized clinical trial conducted in Catalonia, Spain, assesses whether direct transport to an endovascular treatment –capable stroke center vs to the nearest local stroke center benefits patients experiencing intracerebral hemorrhage.
Source: JAMA Neurology - August 21, 2023 Category: Neurology Source Type: research
Caveolin-1 aggravates neurological deficits by activating neuroinflammation following experimental intracerebral hemorrhage in rats
CONCLUSIONS: Our research revealed CAV1 aggravated neurological dysfunction in a rat ICH model. CAV1 knockdown exerted neuroprotective effect by suppressing microglia activation and neuroinflammation after ICH might via the C-Src/CAV1/IKK-β/NF-κB signaling pathway.PMID:37598879 | DOI:10.1016/j.expneurol.2023.114508
Source: Experimental Neurology - August 20, 2023 Category: Neurology Authors: Demao Cao Bing Li Cheng Cao Juyi Zhang Xiang Li Haiying Li Zhengquan Yu Haitao Shen Ming Ye Source Type: research
