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Condition: Septic Shock

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Total 242 results found since Jan 2013.

Clinical experience of infective endocarditis complicated by acute cerebrovascular accidents.
CONCLUSION: Early surgical intervention for IE with ischemic stroke may prevent adverse events, particularly in patients with impaired renal function, diabetes, or staphylococcal infection. A delay in operation of > 30 days is recommended after hemorrhagic stroke. PMID: 26610865 [PubMed - as supplied by publisher]
Source: Asian Journal of Surgery - November 20, 2015 Category: Surgery Authors: Hsu CY, Chi NH, Wang SS, Chen YS, Yu HY Tags: Asian J Surg Source Type: research

Pattern of brain injury in the acute setting of human septic shock
Conclusions: Brain MRI in septic shock patients who developed acute brain dysfunction can reveal leukoencephalopathy and ischemic stroke, which is associated with DIC and increased mortality.
Source: Critical Care - September 18, 2013 Category: Intensive Care Authors: Andrea PolitoFrédéric EischwaldAnne-Laure Le MahoAngelo PolitoEric AzabouDjillali AnnaneFabrice ChrétienRobert StevensRobert CarlierTarek Sharshar Source Type: research

Comparing transesophageal Doppler corrected systolic flow time versus central venous pressure as a guide for fluid resuscitation in septic shock
Conclusion Transesophageal aortic Doppler is a simple, non-invasive tool of guiding fluid therapy in patients with severe sepsis and septic shock. FTC change was a better predictor of fluid responsiveness than CVP in septic shock. There was higher significant difference in SV after resuscitation when using FTC as guidance.
Source: Egyptian Journal of Anaesthesia - January 23, 2016 Category: Anesthesiology Source Type: research

Risk of incident atrial fibrillation after a prior critical illness: A retrospective cohort study.
CONCLUSIONS: Our study explored incident AF among patients with critical illness in their medical history. Patients with septicemia/septic shock were at the highest risk of developing new-onset AF among these critically ill patients. PMID: 30243509 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - September 19, 2018 Category: Internal Medicine Authors: Hu WS, Lin CL Tags: Eur J Intern Med Source Type: research

“A contemporary description of staphylococcus aureus prosthetic valve endocarditis. Differences according to the time elapsed from surgery”
Staphylococcus aureus prosthetic valve endocarditis (SAPVE) has a poor prognosis. There are no large series that accurately describe this entity. This is a retrospective observational study on a prospective cohort from 3 Spanish reference hospitals for cardiac surgery, including 78 definitive episodes of left SAPVE between 1996 and 2016. Fifty percent had a Charlson Index score>5; 53% were health care-related. Twenty percent did not present fever. Complications at diagnosis included: severe heart failure (HF, 29%), septic shock (SS, 17.9%), central nervous system abnormalities (19%), septic metastasis (4%). Hemorrhagic s...
Source: Medicine - August 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Nitrone-based Therapeutics for Neurodegenerative Diseases. Their use alone or in Combination with Lanthionines.
Abstract The possibility of free radical reactions occurring in biological processes led to the development and employment of novel methods and techniques focused on determining their existence and importance in normal and pathological conditions. For this reason the use of Nitrones for spin trapping free radicals came into widespread use in the 1970s and 1980s when surprisingly the first evidence of their potent biological properties was first noted. Since then wide-spread exploration and demonstration of the potent biological properties of phenyl-tert-butylnitrone (PBN) and derivatives were shown in preclinical ...
Source: Free Radical Biology and Medicine - February 15, 2013 Category: Biology Authors: Floyd RA, Castro Faria Neto HC, Zimmerman GA, Hensley K, Towner RA Tags: Free Radic Biol Med Source Type: research

Access to Care for Patients With Time-Sensitive Conditions in Pennsylvania
Conclusion: Reliably matching patient needs to ED resources in time-dependent illness is a critical component of a coordinated emergency care system. Population access to critical interventions for the time-dependent diseases discussed here is limited. A population-based planning approach and improved coordination of care could improve access to interventions for patients with time-sensitive conditions.
Source: Annals of Emergency Medicine - December 23, 2013 Category: Emergency Medicine Authors: Rama A. Salhi, J. Matthew Edwards, David F. Gaieski, Roger A. Band, Benjamin S. Abella, Brendan G. Carr Tags: Health Policy Source Type: research

Predicting Fluid Responsiveness in Acute Liver Failure: A Prospective Study.
CONCLUSIONS: PPV based on pulse contour analysis predicted fluid responsiveness in ALF. PMID: 27984249 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - December 13, 2016 Category: Anesthesiology Authors: Audimoolam VK, McPhail MJ, Willars C, Bernal W, Wendon JA, Cecconi M, Auzinger G Tags: Anesth Analg Source Type: research

Pulse-induced contour cardiac output (PiCCO) combined with passive leg raising test predicting fluid resuscitation in adult patients with septic shock
Publication date: Available online 17 July 2017 Source:The Kaohsiung Journal of Medical Sciences Author(s): Si-Dong Zhan To investigate the clinical value of pulse-induced contour cardiac output (PiCCO) monitoring combined with passive leg raising (PLR) test in predicting fluid responsiveness so as to guide fluid resuscitation in adult septic shock patients managed by rehydration test. One hundred and forty five adult septic shock patients, who were informed to receive PLR tests and rehydration tests. Patients were divided into two groups based on the observation of fluid responsiveness in the rehydration test. Parameters...
Source: The Kaohsiung Journal of Medical Sciences - July 18, 2017 Category: Universities & Medical Training Source Type: research

Clinical – microbiological characterization and risk factors of mortality in infective endocarditis from a tertiary care academic hospital in Southern India
CONCLUSIONS This study reiterates the persistent dominance of rheumatic heart disease in the population studied and α − haemolytic Streptococci as the commonest responsible microorganism.
Source: Indian Heart Journal - August 17, 2017 Category: Cardiology Source Type: research

Clinical - microbiological characterization and risk factors of mortality in infective endocarditis from a tertiary care academic hospital in Southern India.
CONCLUSIONS: This study reiterates the persistent dominance of rheumatic heart disease in the population studied and α - hemolytic Streptococci as the commonest responsible microorganism. PMID: 29716704 [PubMed - in process]
Source: Indian Heart J - March 1, 2018 Category: Cardiology Authors: Subbaraju P, Rai S, Morakhia J, Midha G, Kamath A, Saravu K Tags: Indian Heart J Source Type: research

Pulse-induced contour cardiac output (PiCCO) combined with passive leg raising test predicting fluid resuscitation in adult patients with septic shock
Publication date: Available online 17 July 2017Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Si-Dong ZhanAbstractTo investigate the clinical value of pulse-induced contour cardiac output (PiCCO) monitoring combined with passive leg raising (PLR) test in predicting fluid responsiveness so as to guide fluid resuscitation in adult septic shock patients managed by rehydration test. One hundred and forty five adult septic shock patients, who were informed to receive PLR tests and rehydration tests. Patients were divided into two groups based on the observation of fluid responsiveness in the rehydration test. Param...
Source: The Kaohsiung Journal of Medical Sciences - July 5, 2018 Category: Universities & Medical Training Source Type: research

Effect of acute endotoxemia on analog estimates of mean systemic pressure
Abstract: Dynamic estimates of mean systemic pressure based on a Guytonian analog model (Pmsa) appear accurate under baseline conditions but may not remain so during septic shock because blood volume distribution and resistances between arterial and venous beds may change. Thus, we examined the effect of acute endotoxemia on the ability of Pmsa, estimated from steady-state cardiac output, right atrial pressure, and mean arterial pressure, to reflect our previously validated instantaneous venous return measure of mean systemic pressure (Pmsi), derived from beat-to-beat measures of right ventricular stroke volume and right a...
Source: Journal of Critical Care - June 3, 2013 Category: Intensive Care Authors: Jae Myeong Lee, Olufunmilayo Ogundele, Francis Pike, Michael R. Pinsky Tags: Electronic Articles Source Type: research