A critical analysis of the non-inferiority design of TALENT trial
Publication date: Available online 14 February 2020Source: Indian Heart JournalAuthor(s): S. Saha, P. Kerkar, N.J. GogtayAbstractIn recent years, regulatory approval of stents has been based on studies that have a non-inferiority design, which has its own inherent complexities. We critically appraise in this paper, the TALENT trial which established the non-inferiority of Indian manufactured Supraflex stent (a third generation, sirolimus-eluting stent with an ultra-thin strut thickness) compared to the Xience stent – (an internationally available,everolimus-eluting stent with a thicker strut) for a device-oriented co...
Source: Indian Heart Journal - February 15, 2020 Category: Cardiology Source Type: research

Epidemiological trends of acute coronary syndrome (ACS) in Shimla district of hilly state of Northern India: 6 years data from the prospective HP ACS registry
Publication date: Available online 5 February 2020Source: Indian Heart JournalAuthor(s): Prakash Chand Negi, Kunal Mahajan, Rajeev Merwaha, Sanjeev Asotra, Rajesh SharmaObjectivesThe epidemiological trends of incidence, treatment practices and outcomes are reported from Shimla district of northern state of India.MethodsThe data of clinical characteristics, treatment practices and outcomes of patients with ACS diagnosed using standard criteria was collected systematically from defined hilly geographical region of northern state of India from Jan.2013 to December 2018 as the part of HP ACS registry. The year-wise trends of i...
Source: Indian Heart Journal - February 6, 2020 Category: Cardiology Source Type: research

Unravelling the utility of modern sulfonylureas from cardiovascular outcome trials and landmark trials: expert opinion from an international panel
ConclusionModern SUs can be considered a cardiosafe option for the management of patients with diabetes mellitus and CV disease; thus CVOTs among individuals with T2DM are not required. (Source: Indian Heart Journal)
Source: Indian Heart Journal - February 5, 2020 Category: Cardiology Source Type: research

Soluble Neprilysin: A Versatile Biomarker for Heart Failure, Cardiovascular Diseases and Diabetic complications-A systematic review
Publication date: Available online 4 February 2020Source: Indian Heart JournalAuthor(s): Kumaresan Ramanathan, Giri PadmanabhanAbstractThe potential role of soluble neprilysin as a biomarker has been poorly documented. Hence, the present systematic review emphasizes to explore soluble neprilysin as an emerging biomarker for heart failure, cardiovascular diseases, diabetic kidney diseases and beyond. A systematic review was performed using an online database search in PubMed, Science Direct, Scopus and Cochrane Library. Articles reporting biomarker’s performance to diagnose various diseases in human participants were ...
Source: Indian Heart Journal - February 5, 2020 Category: Cardiology Source Type: research

“Cardiac changes in Children Hospitalized with Severe Acute Malnutrition: A Prospective Study at Tertiary Care Center of Northern India.”
Publication date: Available online 4 February 2020Source: Indian Heart JournalAuthor(s): jain Dharmendra, Sunil Kumar Rao, Dhilip Kumar, Ashok Kumar, Bhupendra Kumar SihagSevere acute malnutrition (SAM) may affect cardiac structure & function. Cardiac changes in sick SAM children have received little attention in literature. Children aged 6 to 60 months with SAM were cases, and age & sex matched children were controls. Cardiac biomarkers levels were measured by quantitative ELISA method & echocardiography was used to assess cardiac changes in all children. Study included 76 children in each group. SAM children ...
Source: Indian Heart Journal - February 5, 2020 Category: Cardiology Source Type: research

Investigation in Short-term Prognosis of Fragmented QRS Complexes in Patients with Acute Myocardial Infarction in Two Groups Received Invasive and Fibrinolytic Therapy
ConclusionThe final results of this study showed that there was no significant difference between the four study groups and arrhythmia status. Therefore, F-QRS was not introduced as an independent predictor of arrhythmia in acute myocardial infarction patients. (Source: Indian Heart Journal)
Source: Indian Heart Journal - January 22, 2020 Category: Cardiology Source Type: research

Prevalence and RIsk factors for Silent Myocardial ischemia (PRISM): A clinico observational study in patients of type 2 diabetes
ConclusionSilent myocardial ischemia is highly prevalent at about one in four asymptomatic diabetic patients. An increased CIMT can be a surrogate marker of higher coronary risk amongst these asymptomatic diabetics. (Source: Indian Heart Journal)
Source: Indian Heart Journal - January 18, 2020 Category: Cardiology Source Type: research

Necessary Complexities When Standardizing Hypertension Protocols in India
Publication date: Available online 13 January 2020Source: Indian Heart JournalAuthor(s): Aayush Visaria, Tina Dharamdasani (Source: Indian Heart Journal)
Source: Indian Heart Journal - January 15, 2020 Category: Cardiology Source Type: research

Unravelling the Utility of Modern Sulfonylureas From CVOTs and Landmark Trials: Expert Opinion from an International Panel
ConclusionModern SUs can be considered a cardiosafe option for the management of patients with diabetes mellitus and cardiovascular disease; thus CVOTs among individuals with T2DM are not required. (Source: Indian Heart Journal)
Source: Indian Heart Journal - January 13, 2020 Category: Cardiology Source Type: research

Acute myocardial infarction in pregnancy: Current diagnosis and management approaches
Publication date: Available online 17 December 2019Source: Indian Heart JournalAuthor(s): Mohan M. Edupuganti, Vyjayanthi GangaAbstractAcute myocardial infarction during pregnancy is a very uncommon condition; atherosclerotic coronary artery disease is by far the most common cause of an acute coronary syndrome in the general population. The causes of an acute coronary syndrome in the pregnant patient are wide and varied. This has important implications with respect to the diagnosis of the etiology and the subsequent management of the cause of the acute coronary syndrome. There are a number of diagnostic tools for the diagn...
Source: Indian Heart Journal - January 10, 2020 Category: Cardiology Source Type: research

National Heart Failure Registry, India: Design and Methods
ConclusionsIn summary, NFHR will be the first nationally representative HF registry aimed at providing crucial information on prevailing aetiology, distribution and pattern based on socio-demographic characteristics, and rate of progression of HF to worse health status. (Source: Indian Heart Journal)
Source: Indian Heart Journal - January 3, 2020 Category: Cardiology Source Type: research

Clinical and Angiographic profile of very young adults presenting with first Acute Myocardial Infarction: Data from a tertiary care center in Central India
Publication date: Available online 3 January 2020Source: Indian Heart JournalAuthor(s): Pradeep P. Deshmukh, Mohit M. Singh, Mukund A. Deshpande, Atul S. RajputAbstractAcute myocardial infarction (AMI) is afflicting younger individuals more frequently nowadays. The present study was planned to evaluate the clinical and angiographic profile in adults aged less than 30 years presenting with first AMI as data from central India is very scarce. This cross sectional study included 41 patients of STEMI with mean age 27 ± 2.8 years. Risk factors were male gender (95.1%), dyslipidemia (51.2%), tobacco consumption (48.8%), o...
Source: Indian Heart Journal - January 3, 2020 Category: Cardiology Source Type: research

Intermediate term outcome after electrogram guided segmental ostial pulmonary vein isolation using an 8 mm tip catheter for paroxysmal atrial fibrillation
ConclusionConventional RF ablation using PV potential-based mapping and ablation with 8 mm tip catheters is safe for patients with PAF. The intermediate term outcome is satisfactory and cost-effective in our setting with limited resources. (Source: Indian Heart Journal)
Source: Indian Heart Journal - December 28, 2019 Category: Cardiology Source Type: research

Prevalence and RIsk factors for Silent Myocardial ischaemia (PRISM): a clinico observational study in patients of type 2 diabetes
ConclusionSilent myocardial ischaemia is highly prevalent at about one in four asymptomatic diabetic patients. An increased CIMT can be a surrogate marker of higher coronary risk amongst these asymptomatic diabetics. (Source: Indian Heart Journal)
Source: Indian Heart Journal - December 24, 2019 Category: Cardiology Source Type: research

Acute myocardial infarction in pregnancy: Current diagnosis and management approaches.
Publication date: Available online 17 December 2019Source: Indian Heart JournalAuthor(s): Mohan M. Edupuganti, Vyjayanthi GangaAbstractAcute myocardial infarction during pregnancy is a very uncommon condition, atherosclerotic coronary artery disease is by far the most common cause of an acute coronary syndrome in the general population. The causes of an acute coronary syndrome in the pregnant patient are wide and varied. This has important implications with respect to the diagnosis of the etiology and the subsequent management of the cause of the acute coronary syndrome. There are a number of diagnostic tools for the diagn...
Source: Indian Heart Journal - December 18, 2019 Category: Cardiology Source Type: research

Clinical characteristics and outcome in patients with a delayed presentation after ST-elevation myocardial infarction and complicated by cardiogenic shock
ConclusionPatients with a delayed presentation after CS-STEMI were younger and more likely to have single-vessel disease. We found a high in-hospital mortality of 42.9%. Appropriate randomized studies are required to evaluate the optimal treatment strategies in these patients. (Source: Indian Heart Journal)
Source: Indian Heart Journal - December 15, 2019 Category: Cardiology Source Type: research

Coronary artery size in North Indian population – Intravascular ultrasound-based study
Publication date: Available online 5 November 2019Source: Indian Heart JournalAuthor(s): Sreenivas Reddy, Suraj Kumar, Jeet Ram Kashyap, Raghavendra Rao, Vikas Kadiyala, Hithesh Reddy, Naindeep Kaur, Vadivelu Ramalingam, Jaspreet KaurAbstractObjectiveThe coronary artery dimensions have important diagnostic and therapeutic implications in management of coronary artery disease (CAD). There is paucity of data on the coronary artery size in the Indian population as measured by intravascular ultrasound (IVUS).MethodsA total of 303 patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) wi...
Source: Indian Heart Journal - December 10, 2019 Category: Cardiology Source Type: research

Intermediate term outcome after electrogram guided segmental ostialpulmonary vein isolation using an 8 mm tip catheter for paroxysmal atrial fibrillation
ConclusionConventional RFA using PV potential based mapping and ablation with 8 mm tip catheters is safe for patients with PAF. Theintermediate term outcome is satisfactory and cost effective in our setting with limited resources. (Source: Indian Heart Journal)
Source: Indian Heart Journal - December 6, 2019 Category: Cardiology Source Type: research

QT Prolongation in HIV-positive Patients: Review Article
ConclusionBaseline and follow-up EKG in the susceptible population is suggested. (Source: Indian Heart Journal)
Source: Indian Heart Journal - December 3, 2019 Category: Cardiology Source Type: research

Medical referrals in private practice: Need to keep the fine fabric intact
Publication date: Available online 2 December 2019Source: Indian Heart JournalAuthor(s): B.Sadananda Naik (Source: Indian Heart Journal)
Source: Indian Heart Journal - December 2, 2019 Category: Cardiology Source Type: research

Standardizing hypertension management in a primary care setting in India through a protocol based model
Publication date: Available online 26 November 2019Source: Indian Heart JournalAuthor(s): Priyanka Satish, Aditya Khetan, Shyamsundar Raithatha, Punam Bhende, Richard JosephsonAbstractHypertension is a leading cause of death in India. Control rates of hypertension are abysmal, even for people on treatment. There are a number of barriers to adequate control of hypertension in India, including therapeutic inertia and the lack of a systematic, simplified approach. Standardizing hypertension management through an evidence based model that sets thresholds for diagnosis, treatment goals, follow up intervals and choice of drugs c...
Source: Indian Heart Journal - November 27, 2019 Category: Cardiology Source Type: research

Clinical Characteristics and Outcome in Patients with a Delayed Presentation after STEMI and Complicated by Cardiogenic Shock
ConclusionPatients with a delayed presentation following CS-STEMI were younger and more likely to have single-vessel disease. We found a high in-hospital mortality of 42.9%. Appropriate randomized studies are required to evaluate the optimal treatment strategies in these patients. (Source: Indian Heart Journal)
Source: Indian Heart Journal - November 22, 2019 Category: Cardiology Source Type: research

Fragmented QRS complex is an independent predictor of plaque burden in patients at Intermediate Risk of Coronary Artery Disease
Publication date: Available online 21 November 2019Source: Indian Heart JournalAuthor(s): Ragab A. Mahfouz, Mohamad Arab, Mohamed Abdelhamid, Ahmad ElzayatAbstractObjectiveWe aimed to evaluate the relationship between fragmented QRS complex and plaque burden in patients presented with typical chest pain and deemed to have intermediate pretest probability of CAD using coronary tomographic angiography (CCTA).MethodsWe studied electrocardiograms (ECGs) obtained from 172 subjects (47.5±9.5 years, 125 were men) presented with chest pain and had intermediate pretest probability for CAD. The presence and evaluation of CAD ...
Source: Indian Heart Journal - November 22, 2019 Category: Cardiology Source Type: research

Leadless Pacemakers – the path to safer pacing?
This article provides a contemporary critique of design types, evidence base and existing limitations of this nascent technology. (Source: Indian Heart Journal)
Source: Indian Heart Journal - November 21, 2019 Category: Cardiology Source Type: research

To study the usefulness and comparison of myocardial strain imaging by 2D and 3D echocardiography for early detection of cardiotoxicity in patients undergoing cardiotoxic chemotherapy
Publication date: Available online 19 November 2019Source: Indian Heart JournalAuthor(s): Shamshad Alam, Sharad Chandra, Gaurav Chaudhary, Akhil Sharma, Monika Bhandhari, Pravesh Vishwakarma, Akshaya Pradhan, Rishi Sethi, Sudhanshu K. Dwivedi, Varun S. NarainAbstractBackgroundChemotherapy-induced cardiotoxicity constitutes subclinical myocardial dysfunction, arrhythmias, pericarditis, coronary vasospasm, significant symptomatic heart failure. Anthracyclines pose higher risk for long-term cardiac dysfunction, with increased incidences of morbidity and mortality. Hence, early detection of chemotherapy induced cardiac dysfunc...
Source: Indian Heart Journal - November 21, 2019 Category: Cardiology Source Type: research

Assessment of right ventricular systolic function in heart failure with preserved, reduced and mid-range ejection fraction
Publication date: Available online 20 November 2019Source: Indian Heart JournalAuthor(s): Shaimaa MostafaAbstractBackgroundFew studies have evaluated right ventricle systolic function in different categories of heart failure despite its effect on outcomes.Methods and resultssingle-centre, cross-sectional study included 150 patients, 50 patients in each category of HF: group I, preserved; group II, mid-range, group III reduced ejection fraction. Left ventricular systolic function was assessed by 3D echo, and right ventricular systolic function was assessed by fraction area change (FAC), tricuspid annular plane systolic excu...
Source: Indian Heart Journal - November 21, 2019 Category: Cardiology Source Type: research

Coronary Artery size in North Indian population – Intravascular ultrasound based study
Publication date: Available online 5 November 2019Source: Indian Heart JournalAuthor(s): S. Reddy, Suraj Kumar, J.R. Kashyap, K. Raghavendra, K. Vikas, Hithesh Reddy, N. Kaur, R. Velu, J. KaurAbstractObjectiveThe coronary artery dimensions have important diagnostic and therapeutic implications in management of coronary artery disease. There is paucity of data on the coronary artery size in Indians by intravascular ultrasound.MethodsA total of 303 patients with acute coronary syndrome undergoing percutaneous intervention with intravascular ultrasound underwent analysis along with quantitative coronary angiogram (QCA). Of th...
Source: Indian Heart Journal - November 5, 2019 Category: Cardiology Source Type: research

9p21.3 Coronary Artery Disease Risk Locus and Interferon Alpha 21: Association study in an Asian Indian population
ConclusionsIFNA21 may be involved in inflammatory processes in an age dependent manner and in progression of CAD. This IFNA21 mediated mechanism may be more active in females. Several 9p21 SNPs may modulate inflammatory processes mediated by IFNA21, and may therefore contribute to pathophysiology of CAD. (Source: Indian Heart Journal)
Source: Indian Heart Journal - October 27, 2019 Category: Cardiology Source Type: research

Correlation of urinary cotinine with cardiovascular risk factors in pan masala tobacco users
Publication date: Available online 22 October 2019Source: Indian Heart JournalAuthor(s): Shrestha Sanjeeb, Mishra Deebya Raj, Dhakal Niraj, Bhandari Suresh, Khanal Sagar, Lamsal MadhabAbstractBackgroundTobacco consumption is considered as one of the major risk factors for Cardiovascular (CV) morbidity. However, the effect of Paan Masala Tobacco (PMT) (a type of smokeless tobacco) consumption has not been well studied in our context. Our study is aimed to find an association of CV risk factors between PMT users and nonusers and to correlate those parameters with urinary cotinine level, a degradation product of nicotine occu...
Source: Indian Heart Journal - October 24, 2019 Category: Cardiology Source Type: research

Permanent HIS bundle Pacing Feasibility in Routine Clinical Practice: Experience from an Indian Center
Publication date: Available online 18 September 2019Source: Indian Heart JournalAuthor(s): Rakesh Sarkar, Daljeet Kaur, Muthiah Subramanian, Sachin Yalagudri, C. Sridevi, Soumen Devidutta, Debabrata Bera, Calambur NarasimhanAbstractThere is a paucity of experience regarding His bundle pacing (HBP) at laboratories initially attempting the procedure, especially in the Indian scenario. Patient who underwent HBP were selected for pacing therapy or in lieu of cardiac resynchronization therapy (CRT) at a single center. Among 22 patients attempted, 19 patients underwent successful implant, achieving selective HBP in 14 patients. ...
Source: Indian Heart Journal - October 23, 2019 Category: Cardiology Source Type: research

Mitral valve calcium assessment: An independent predictor of balloon valvuloplasty results
Publication date: Available online 22 October 2019Source: Indian Heart JournalAuthor(s): Ricardo A. Sarmiento, Raúl Solernó, Rodrigo Blanco, Federico Giachello, Agustin Hauqui, Martín Oscos, Federico Blanco, Gerardo Gigena, Jorge Lax, Pablo PedroniAbstractObjectivePercutaneous mitral valvuloplasty (PMV) is an effective treatment for patients with mitral valve stenosis. Echocardiographic score (ES) is a useful predictor of outcomes. However, mitral valve calcification (MVC) has been shown to predict immediate results even in patients with otherwise low ES. We sought to evaluate the usefulness of MVC ass...
Source: Indian Heart Journal - October 23, 2019 Category: Cardiology Source Type: research

Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Stroke: An Updated Systematic Review and Meta-Analysis
Publication date: Available online 22 October 2019Source: Indian Heart JournalAuthor(s): Sunny Goel, Shanti Patel, Elina Zakin, Ravi Teja Pasam, Joseph Gotesman, Bilal Ahmad Malik, Sergey Ayzenberg, Robert Frankel, Jacob ShaniAbstractObjectivesTo compare safety and efficacy of Patent Foramen Ovale (PFO) closure compared with medical therapy in patients with cryptogenic stroke (CS)BackgroundThe role of PFO closure in preventing recurrent stroke in patients with prior CS has been controversial.MethodsWe searched PubMed, EMBASE, the Cochrane Central Register of Controlled trials, and the clinical trial registry maintained at ...
Source: Indian Heart Journal - October 23, 2019 Category: Cardiology Source Type: research

Evaluation of intracoronary blood from obstructive vessel in patients of ST-elevation myocardial infarction undergoing PPCI
ConclusionThe evaluation of intracoronary blood provides no additional information regarding the prognosis and short-term (30-day) outcome of the patients when compared with peripheral blood. However, there was a significant intracoronary hyperlactatemia in patients presenting late after symptom onset. SBP was also significantly less in patients with high intracoronary lactate, which signifies that predominant cause of hyperlactatemia was systemic hypoperfusion rather than local increase in lactate levels. (Source: Indian Heart Journal)
Source: Indian Heart Journal - October 18, 2019 Category: Cardiology Source Type: research

Incidence and impact of ischemic and hemorrhagic stroke after left ventricular assist device implantation: A nationwide study
This study aims to analyze the incidence and short-term outcomes associated with stroke (ischemic and hemorrhagic) after implantation of LVAD.MethodsStudy cohorts were identified from the National Inpatient Sample database from January 2009 to September 2015 using the International Classification of Diseases, Ninth Revision codes. The primary outcome was an incidence of stroke, and secondary outcomes were the associated mortality, length of stay, and cost of hospitalization. A multivariate logistic regression analysis was performed to analyze adjusted in-hospital mortality.ResultsUse of LVADs increased significantly from 2...
Source: Indian Heart Journal - October 6, 2019 Category: Cardiology Source Type: research

Atherosclerostic Cardiovascular Disease Risk Score: Are Indians Underestimating the Risk of Cardiovascular Disease?
Publication date: Available online 30 August 2019Source: Indian Heart JournalAuthor(s): Ashish Kumar, Mariam Shariff (Source: Indian Heart Journal)
Source: Indian Heart Journal - October 1, 2019 Category: Cardiology Source Type: research

Sex differences in 30-day readmission rates, etiology, and predictors after transcatheter aortic valve replacement
Publication date: Available online 9 September 2019Source: Indian Heart JournalAuthor(s): Rajkumar Doshi, Mohamed Taha, Mihir Dave, Rupak Desai, Nageshwara GullapalliAbstractBackgroundThe aim of this study is to analyze sex-specific readmission rates, etiology, and predictors of readmission after transcatheter aortic valve replacement (TAVR). Readmissions after TAVR are common, contributing to increased health care utilization and costs. Many factors have been discovered as predictors of readmission; however, sex-specific disparities in readmission rates are limited.MethodsBetween January 2012 and September 2015, adult pat...
Source: Indian Heart Journal - October 1, 2019 Category: Cardiology Source Type: research

Evaluation Of Intra-Coronary Blood From Obstructive Vessel In Patients Of St-Elevation Myocardial Infarction Undergoing Primary Pci
ConclusionThe evaluation of intracoronary blood provides no additional information regarding the prognosis and short-term (30-days) outcome of the patients when compared to peripheral blood. However, there was significant intracoronary hyperlactemia in patients presenting late after symptom onset. SBP was also significantly less in patients with high intracoronary lactate, which signifies that predominant cause of hyperlactemia was systemic hypoperfusion rather than local increase in lactate levels. (Source: Indian Heart Journal)
Source: Indian Heart Journal - September 28, 2019 Category: Cardiology Source Type: research

Orthostatic hypotension is associated with new-onset atrial fibrillation: Systemic review and meta-analysis
Publication date: Available online 14 August 2019Source: Indian Heart JournalAuthor(s): Narut Prasitlumkum, Jakrin Kewcharoen, Natthapon Angsubhakorn, Pakawat Chongsathidkiet, Pattara RattanawongAbstractIntroductionOrthostatic hypotension (OH) is common among elderly patients. Its presence may herald severe underlying comorbidities and be associated with a higher risk of mortality. Interestingly, recent studies suggest that OH is associated with new-onset atrial fibrillation (AF). However, a systematic review and meta-analysis of the literature has not been performed. We assessed the association between AF and OH through a...
Source: Indian Heart Journal - September 26, 2019 Category: Cardiology Source Type: research

Thrombolysis with Reteplase in Acute Pulmonary Embolism
ConclusionsDouble bolus reteplase given with heparin is effective in the treatment of high, intermediate risk pulmonary embolism with minimal risk of bleeding. (Source: Indian Heart Journal)
Source: Indian Heart Journal - September 22, 2019 Category: Cardiology Source Type: research

Duration of in-hospital cardiopulmonary resuscitation and its effect on survival
ConclusionOur study shows that CPR duration is inversely associated with the establishment rates of ROSC. Most of the benefits of CPR can be achieved in the first fifteen minutes, and a further increase in the duration of CPR provides a minimal gain. Still, survival was achievable till 38 mins in some cases, and the ideal duration of resuscitation should remain a bedside decision taking into consideration the whole clinical picture. (Source: Indian Heart Journal)
Source: Indian Heart Journal - September 20, 2019 Category: Cardiology Source Type: research

Prevalence of Hypertension among Indian Adults: Results from the Great India Blood Pressure Survey
ConclusionThere is a high prevalence of hypertension, with almost one in every three Indian-adult affected. (Source: Indian Heart Journal)
Source: Indian Heart Journal - September 19, 2019 Category: Cardiology Source Type: research

Permanent His-bundle pacing feasibility in routine clinical practice: experience from Indian centre
Publication date: Available online 18 September 2019Source: Indian Heart JournalAuthor(s): Rakesh Sarkar, Daljeet Kaur, Muthiah Subramanian, Sachin Yalagudri, C. Sridevi, Soumen Devidutta, Debabrata Bera, Calambur NarasimhanAbstractThere is a paucity of experience regarding His-bundle pacing (HBP) at labs initially attempting the procedure, especially in the Indian scenario. Patient underwent HBP were either selected for pacing therapy or in lieu of CRT at a single center. Among 22 patients attempted, 19 patients underwent successful implant achieving selective HBP in 14. There was a significant improvement of LVEF(49.3&pl...
Source: Indian Heart Journal - September 19, 2019 Category: Cardiology Source Type: research

Incidence and Impact of Ischemic and Hemorrhagic Stroke post Left Ventricular Assist Device Implantation: A Nationwide Study
This study aims to analyze the incidence and short-term outcomes associated with stroke (ischemic and hemorrhagic) after implantation of LVAD.MethodsStudy cohorts were identified from the National Inpatient Sample database from January 2009 to September 2015 using ICD 9 codes. The primary outcome was an incidence of stroke and secondary outcomes were associated mortality, length of stay and cost of hospitalization. Multivariate logistic regression analysis was performed to analyze adjusted in-hospital mortality.ResultsUse of LVAD increased significantly from 2009 to 2014 (2,278 in 2009 to 3,730 in 2014 (Ptrend
Source: Indian Heart Journal - September 14, 2019 Category: Cardiology Source Type: research

A Prospective Study of Contrast Preservation Using Ultra-Low Contrast Delivery Technique Versus Standard Automated Contrast Injector System in Coronary Procedures
Publication date: Available online 10 September 2019Source: Indian Heart JournalAuthor(s): Adam Stys, Maheedhar Gedela, Udit Bhatnagar, Marian Petrasko, Hazem Dawoud, Tadeusz Malinski, Tomasz StysAbstractObjectiveWe aimed to assess the decrease in contrast media volume (CMV) with ultra-low contrast delivery technique (ULCD) developed at our institution versus the usual automated contrast injector system (ACIS) contrast delivery in coronary procedures.MethodsWe analyzed the amount of contrast given in the consecutive 204 patients of the operators who use ULCD technique versus other operators consecutive 200 patients who use...
Source: Indian Heart Journal - September 12, 2019 Category: Cardiology Source Type: research

Prognostic Value of Frontal QRS-T Angle in Predicting Survival After Primary Percutaneous Coronary Revascularization/Coronary Artery Bypass Grafting for ST Elevation Myocardial Infarction
Publication date: Available online 9 September 2019Source: Indian Heart JournalAuthor(s): Abhishek C. Sawant, Aishwarya Bhardwaj, Shantanu Srivatsa, Srilekha Sridhara, Meghana Prakash Hiriyur Prakash, Nidhi Kanwar, Janelle Rodriguez, Gary Tse, Tong Liu, Arnav Kumar, Hiroko Beck, Sanjay S. SrivatsaAbstractBackgroundFrontal QRST Angle (FQRST) has previously been correlated with mortality in patients with stable coronary artery disease, but its role as survival predictor following STEMI remains unknown.MethodsWe evaluated 267 consecutive patients with STEMI undergoing reperfusion or coronary artery bypass grafting. Data asses...
Source: Indian Heart Journal - September 11, 2019 Category: Cardiology Source Type: research

CHA2DS2-VASc Score as a novel predictor for Contrast-Induced Nephropathy after Percutaneous Coronary Intervention in Acute Coronary Syndrome
ConclusionIn patients with ACS undergoing PCI, CHA2DS2-VASc score can be used as a novel, simple and a sensitive diagnostic tool for the prediction of CIN. (Source: Indian Heart Journal)
Source: Indian Heart Journal - September 11, 2019 Category: Cardiology Source Type: research

Incidence and Predictors of Super-response to Cardiac Resynchronization Therapy
ConclusionIn our study, 27.6% of patients were super-responders and dilated cardiomyopathy, absence of a prior history of MI and prior RV apical pacing tended to predict a super-response to CRT. (Source: Indian Heart Journal)
Source: Indian Heart Journal - September 11, 2019 Category: Cardiology Source Type: research

Cardiovascular manifestations of people living with HIV/AIDS: Report from a hot spot in eastern india
Publication date: Available online 9 September 2019Source: Indian Heart JournalAuthor(s): D.R. Trinath Kumar Mishra, D.R. Sura Kishor Mishra, D.R. Subhasish SinghAbstractObjectiveTo study the profile and characteristics of cardiovascular abnormalities among patients living with HIV/AIDS at a tertiary care hospital in India. The association of cardiovascular abnormalities with the CD4 count and disease stages, according to the World Health Organization (WHO) classification, was also analyzed.MethodsA total of 200 patients with HIV/AIDS were compared with 50 healthy controls. All patients underwent blood investigations, ches...
Source: Indian Heart Journal - September 11, 2019 Category: Cardiology Source Type: research

Sex-differences in 30-day Readmission Rates, Etiology And Predictors After Trans-Catheter Aortic Valve Replacement
Publication date: Available online 9 September 2019Source: Indian Heart JournalAuthor(s): Rajkumar Doshi, Mohamed Taha, Mihir Dave, Rupak Desai, Nageshwara GullapalliAbstractBackgroundThe aim of this study is to analyze sex-specific readmission rates, etiology, and predictors of readmission after transcatheter aortic valve replacement (TAVR). Readmissions post-TAVR is common, contributing to increased healthcare utilization and costs. Many factors have been discovered as predictors of readmission, however, sex-specific disparities in readmission ratesis limited.MethodsBetween January 2012 and September 2015, adult patients...
Source: Indian Heart Journal - September 11, 2019 Category: Cardiology Source Type: research

Guidelines for the management of common congenital heart diseases in India: A consensus statement on indications and timing of intervention
Publication date: Available online 12 August 2019Source: Indian Heart JournalAuthor(s): Anita Saxena, Jay Relan, Ravi Agarwal, Neeraj Awasthy, Sushil Azad, Manisha Chakrabarty, Kulbhushan S. Dagar, Velayoudam Devagourou, Baiju S. Dharan, Saurabh K. Gupta, Krishna S. Iyer, M. Jayranganath, Raja Joshi, B.R.J. Kannan, Ashish Katewa, Vikas Kohli, Shyam S. Kothari, K.M. Krishnamoorthy, Snehal Kulkarni, Rohit Manoj KumarAbstractIntroductionA number of guidelines are available for management of congenital heart diseases from infancy to adult life. However, these guidelines are for patients living in high-income countries. Separat...
Source: Indian Heart Journal - August 30, 2019 Category: Cardiology Source Type: research