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Supporting Post-Stroke Language and Cognition with Pharmacotherapy: Tools for Each Phase of Care
AbstractPurpose of ReviewThere is enormous enthusiasm for the possibility of pharmacotherapies to treat language deficits that can arise after stroke. Speech language therapy remains the most frequently utilized and most strongly evidenced treatment, but the numerous barriers to patients receiving the therapy necessary to recover have motivated the creation of a relatively modest, yet highly cited, body of evidence to support the use of pharmacotherapy to treat post-stroke aphasia directly or to augment traditional post-stroke aphasia treatment. In this review, we survey the use of pharmacotherapy to preserve and support l...
Source: Current Neurology and Neuroscience Reports - June 5, 2023 Category: Neuroscience Source Type: research

Research trends of the neuroimaging in aphasia: A bibliometric analysis and visualization analysis from 2004 to 2021
ConclusionThe results of this bibliometric study revealed the following three research hotspots in the neuroimaging of aphasia: clarifying the connotation of the most recognized language processing model, the dual-stream model, exploring the injury mechanism based on the dual-stream model and the recovery mechanism involving the left and right hemispheres of PSA, and determining the diagnostic criteria for PPA variants. A major research trend is to combine new neuroimaging technology, such as PET tracer technology, to realize the visual presentation of disease-specific proteins to improve the pathological diagnostic criter...
Source: Frontiers in Human Neuroscience - July 15, 2022 Category: Neuroscience Source Type: research

Return to Work for People With Aphasia
Right now, about 2.5 million people in the United States are living with aphasia after stroke.1 Aphasia can make it difficult to talk, listen, read, and/or write. Stroke is the most common cause of aphasia, but it can also happen after a traumatic brain injury (eg, blow to the head), a brain tumor, brain infection, or a neurodegenerative disease (eg, Alzheimer's dementia).2 Many people with aphasia are of working age, and this number is going up as more young people in the United States are sustaining stroke.
Source: Archives of Physical Medicine and Rehabilitation - April 5, 2022 Category: Rehabilitation Authors: Natalie Gilmore Tags: INFORMATION/EDUCATION PAGE Source Type: research

Representation in Aphasia Research: An Examination of U.S. Treatment Studies Published Between 2009 and 2019
DISCUSSION: Despite being highlighted as an issue by Ellis (2009), less than 30% of recent aphasia treatment studies reported race or ethnicity, and participants do not appear to be demographically representative compared with estimates of stroke survivors living in the United States. These issues may negatively impact the ecological validity of aphasia treatment research. Aphasia researchers should more consistently report participant race and ethnicity and follow current guidelines for increasing the demographic representation of women and minorities.PMID:35344392 | DOI:10.1044/2022_AJSLP-21-00269
Source: American Journal of Speech-Language Pathology - March 28, 2022 Category: Speech-Language Pathology Authors: Brandon Nguy Yina M Quique Robert Cavanaugh William S Evans Source Type: research

National Institutes of Health Stroke Scale: comparison of the original versus a modified version for Singapore culture
CONCLUSION: There are cultural issues with several dysphasia objects in the original NIHSS as evidenced by high error rates, which were lowered with more culturally suitable alternatives. This study formed a basis to derive a more suitable NIHSS version for English-speaking subjects in Singapore.PMID:34600450 | DOI:10.11622/smedj.2021126
Source: Singapore Medical Journal - October 3, 2021 Category: General Medicine Authors: Shu Han Lim Tai Yan Guek Fung Peng Woon Deirdre Dan Yi Tay Shu Swen Ho Szu Chyi Ng Deidre Anne De Silva Source Type: research

"Personal road map for recovery:" examining the therapeutic use of weblogs by stroke survivors with aphasia.
CONCLUSION: Weblog writing was therapeutic for stroke survivors with aphasia. Authors reported benefits across cognitive, psychological, emotional, and social domains. Health professionals should consider recommending weblog writing, journaling, or other methods of writing for stroke survivors with aphasia. Implications for rehabilitation Creating illness weblog posts can be therapeutically beneficial for stroke survivors with aphasia as a tool that addresses psychological, emotional, and social aspects in their recovery. Blogging appeared to offer a medium for stroke survivors with aphasia to practice writing, to express ...
Source: Disability and Rehabilitation - August 31, 2020 Category: Rehabilitation Authors: Carcello K, McLennon S Tags: Disabil Rehabil Source Type: research

The Cincinnati Prehospital Stroke Scale Compared to Stroke Severity Tools for Large Vessel Occlusion Stroke Prediction.
Conclusions: In this large sample of real-world prehospital patient encounters, the CPSS demonstrated similar predictive performance characteristics compared to the RACE, LAMS, and VAN for detecting LVO stroke. Prior to implementing a specific screening tool, EMS agencies should evaluate ease of use and associated implementation costs. Scored 0-3, the simple, widely-used CPSS may serve as a favorable prehospital screening instrument for LVO detection with a cut-point of 2 or higher maximizing the tradeoff between sensitivity and specificity. PMID: 32017644 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - February 6, 2020 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Benefits of MRI for Patients With Low-risk Transient or Persistent Minor Neurologic Deficits
More than 1 million patients receive a diagnosis of stroke or transient ischemic attack (TIA) in the United States each year. These patients are at increased risk of stroke during the first few weeks after the initial event, with the greatest risk during the first 2 days. Evidence-based secondary preventive measures are available to lower the risk of recurrent ischemic events, but for these measures to be effectively implemented, patients with stroke or TIA must be rapidly and correctly identified. Accurate diagnosis is important because some secondary preventive strategies carry risks of their own and are usually not appr...
Source: JAMA Neurology - September 23, 2019 Category: Neurology Source Type: research

Gender differences in aphasia outcomes: evidence from the AphasiaBank.
CONCLUSIONS & IMPLICATIONS: This study offers evidence of gender differences in aphasia severity, global communication impairment and lower scores on individual subtests used to derive the WAB-R AQ. The limitations of the study with suggestions for future directions are presented. PMID: 31257676 [PubMed - as supplied by publisher]
Source: International Journal of Language and Communication Disorders - June 29, 2019 Category: Speech-Language Pathology Authors: Sharma S, Briley PM, Wright HH, Perry JL, Fang X, Ellis C Tags: Int J Lang Commun Disord Source Type: research

Robot-Assisted Therapy in Upper Extremity Hemiparesis: Overview of an Evidence-Based Approach
Conclusion Robotic therapy has matured and represents an embodiment of a paradigm shift in neurorehabilitation following a stroke: instead of focusing on compensation, it affords focus in ameliorating the impaired limb in line with concepts of neuroplasticity. This technology-based treatment provides intensity, interactivity, flexibility, and adaptiveness to patient's performance and needs. Furthermore, it increases the productivity of rehabilitation care. Of course, efficiency must be discussed within a local perspective. For example, following the cost containment shown in the VA ROBOTICS study (46), the UK Nati...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Neuroimaging and Neurolaw: Drawing the Future of Aging
Vincenzo Tigano1, Giuseppe Lucio Cascini2, Cristina Sanchez-Castañeda3, Patrice Péran4 and Umberto Sabatini5* 1Department of Juridical, Historical, Economic and Social Sciences, University of Magna Graecia, Catanzaro, Italy 2Department of Experimental and Clinical Medicine, University of Magna Graecia, Catanzaro, Italy 3Department of Clinical Psychology and Psychobiology, University of Barcelona, Barcelona, Spain 4ToNIC, Toulouse NeuroImaging Center, Université de Toulouse, Inserm, UPS, Toulouse, France 5Department of Medical and Surgical Sciences, University of Magna Graecia, Catanzaro, ...
Source: Frontiers in Endocrinology - April 7, 2019 Category: Endocrinology Source Type: research

Counselling training for speech-language therapists working with people affected by post-stroke aphasia: a systematic review.
CONCLUSIONS: Research in counselling training for speech-language therapists working in post-stroke aphasia is limited, with a small number of primarily low-quality studies available. Training in generic counselling skills and brief psychological approaches with support from mental health professionals in the stroke workplace enabled speech-language therapists to feel knowledgeable, skilled and confident to address the psychological well-being of people affected by post-stroke aphasia. Evidence about the effectiveness of counselling training on speech-language therapists' confidence and competence in practice and on client...
Source: International Journal of Language and Communication Disorders - February 13, 2019 Category: Speech-Language Pathology Authors: Sekhon JK, Oates J, Kneebone I, Rose M Tags: Int J Lang Commun Disord Source Type: research

Abstract #7: HD-tDCS to contralesional hemisphere to enhance treatment outcomes in persons with stroke-induced aphasia
Background: Chronic aphasia, or language difficulty persisting beyond one year post-stroke, affects over 2.5 million individuals in the United States. Treatment response varies and language abilities are rarely restored. Intact, connected ipsilesional language areas and improved interhemispheric balance following stroke are consistent predictors of recovery. A promising approach to target these brain dynamics is using high-definition transcranial direct current stimulation (HD-tDCS) to deliver focal cathodal current to right frontal areas in the contralesional hemisphere, combined with efficacious behavioral treatment that...
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: J.D. Richardson, S.G.H. Dalton, J.F. Cavanagh, C. Shultz, J. Adams Source Type: research

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