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Condition: Dementia

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Vascular Cognitive Disorders and Depression After First-Ever Stroke: The Fogarty-Mexico Stroke Cohort
Background and Purpose: Stroke is the major cause of vascular behavior and cognitive disorders worldwide. In developing countries, there is a dearth of information regarding the public health magnitude of stroke. The aim of the Fogarty-Mexico cohort was to assess the prevalence of vascular behavioral and cognitive disorders, ranging from mild vascular cognitive impairment (VCI) to vascular dementia (VaD), in a cohort of acute first-ever symptomatic stroke patients in Mexico. Methods: A total of 165 consecutive, first-ever stroke patients admitted to the National Institute of Neurology and Neurosurgery in Mexico City, were ...
Source: Cerebrovascular Diseases - November 20, 2014 Category: Neurology Source Type: research

Stroke Suggests Increased Risk of Dementia.
Conclusions: The findings of this study suggest that stroke confers an increased risk of dementia, especially in the elderly and in patients with hemorrhagic stroke. We advocate the need for close observation and enhanced health education programs to benefit patients with stroke. PMID: 25731623 [PubMed - as supplied by publisher]
Source: Current Alzheimer Research - March 2, 2015 Category: Neurology Authors: Huang CY, Li YC, Wang HK, Sung PS, Wang LC, Sun YT, Pan CH, Tsai KJ Tags: Curr Alzheimer Res Source Type: research

Adverse Influence of Pre-Stroke Dementia on Short-Term Functional Outcomes in Patients with Acute Ischemic Stroke: The Fukuoka Stroke Registry
Background: Dementia and stroke are major causes of disability in the elderly. However, the association between pre-stroke dementia and functional outcome after stoke remains unresolved. We aimed to determine this association in patients with acute ischemic stroke.Methods: Among patients registered in the Fukuoka Stroke Registry from June 2007 to May 2015, 4,237 patients with ischemic stroke within 24 h of onset, who were functionally independent before the onset, were enrolled in this study. Pre-stroke dementia was defined as any type of dementia that was present prior to the index stroke. Primary and secondary study outc...
Source: Cerebrovascular Diseases - December 12, 2016 Category: Neurology Source Type: research

Stroke risk factors, post stroke anxiety and neurocognitive function (s36.003)
Conclusions:As in other contexts, the prevalence of clinically significant anxiety after stroke in this low income population is high. It is frequently co-morbid with depression and associated with cognitive impairment in stroke survivors.Study Supported by:National Institute of Neurological Disorders and Stroke (NINDS-U01 NS079179) and GACD.Disclosure: Dr. Owolabi has nothing to disclose. Dr. Akinyemi has nothing to disclose. Dr. Akinyemi has nothing to disclose. Dr. Gebregziabher has nothing to disclose. Dr. Uvere has nothing to disclose. Dr. Ovbiagele has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Owolabi, M., Akinyemi, R., Akinyemi, J., Gebregziabher, M., Uvere, E., Ovbiagele, B. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Systematic Review and Meta-Analysis of Prevalence in Post-Stroke Neurocognitive Disorders in Hospital-Based Studies.
CONCLUSION: More than half of stroke survivors experience post-stroke NCD, corresponding to mild post-stroke NCD in two-thirds of cases and major post-stroke NCD in one-third of cases. Harmonization of stroke assessment and cognitive score thresholds is urgently needed to allow more accurate estimation of post-stroke NCD prevalence, especially mild post-stroke NCD. PMID: 30504699 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - December 8, 2018 Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research

Association of diabetes with stroke and post-stroke dementia: A population-based cohort study.
DISCUSSION: Diabetes, but not prediabetes, is associated with an increased risk of ischemic stroke and post-stroke dementia. PMID: 32489021 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - June 4, 2020 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Acupuncture May Decrease the Incidence of Post-stroke Dementia: A Taiwan Nationwide Retrospective Cohort Study
Conclusions: The association between stroke and dementia existed in both sexes, more prominent in male. Patients with stroke receiving acupuncture treatments showed decreased risk of dementia. Care must be taken evaluating these results because this study was limited to lack of information regarding lifestyles, stroke severities, and acupuncture methods that were used in treatments.
Source: Frontiers in Neurology - May 21, 2021 Category: Neurology Source Type: research

Sex differences in post-stroke cognitive decline: A population-based longitudinal study of nationally representative data
ConclusionFemales, in contrast to males, experience post-stroke cognitive deficits, particularly during early post-stroke period. Identifying the sex-specific stroke characteristics contributing to differences in post stroke cognitive decline may inform future strategies for reducing the burden of post-stroke cognitive impairment and dementia.
Source: PLoS One - May 6, 2022 Category: Biomedical Science Authors: Abdulaziz T. Bako Source Type: research

Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach
AbstractDue to the reactive medical approach applied to disease management, stroke has reached an epidemic scale worldwide. In 2019, the global stroke prevalence was 101.5 million people, wherefrom 77.2 million (about 76%) suffered from ischemic stroke; 20.7 and 8.4 million suffered from intracerebral and subarachnoid haemorrhage, respectively. Globally in the year 2019 — 3.3, 2.9 and 0.4 million individuals died of ischemic stroke, intracerebral and subarachnoid haemorrhage, respectively. During the last three decades, the absolute number of cases increased substantially. The current prevalence of stroke is 110 million ...
Source: EPMA Journal - November 17, 2022 Category: International Medicine & Public Health Source Type: research

Pyramidal neurons of the prefrontal cortex in post-stroke, vascular and other ageing-related dementias
Dementia associated with cerebrovascular disease is common. It has been reported that ~30% of elderly patients who survive stroke develop delayed dementia (post-stroke dementia), with most cases being diagnosed as vascular dementia. The pathological substrates associated with post-stroke or vascular dementia are poorly understood, particularly those associated with executive dysfunction. Three separate yet interconnecting circuits control executive function within the frontal lobe involving the dorsolateral prefrontal cortex, anterior cingulate cortex and the orbitofrontal cortex. We used stereological methods, along with ...
Source: Brain - August 13, 2014 Category: Neurology Authors: Foster, V., Oakley, A. E., Slade, J. Y., Hall, R., Polvikoski, T. M., Burke, M., Thomas, A. J., Khundakar, A., Allan, L. M., Kalaria, R. N. Tags: Original Articles Source Type: research

Dementia prediction for people with stroke in populations: is mild cognitive impairment a useful concept?
Conclusion: criteria for MCI do not appear to capture risk of dementia in the context of stroke in the population. In stroke cases, subjective and objective cognitive performance predicts dementia and these variables could possibly be incorporated into dementia risk models for stroke cases. Identifying individuals with stroke at greatest risk of dementia has important implications for treatment and intervention.
Source: Age and Ageing - December 4, 2014 Category: Geriatrics Authors: Stephan, B. C. M., Minett, T., Muniz Terrera, G., Matthews, F. E., Brayne, C. Tags: Research Papers Source Type: research

Epidemiology of stroke and transient ischemic attacks: Current knowledge and perspectives.
Authors: Béjot Y, Daubail B, Giroud M Abstract Because of the growing size and aging of the world's population, the global burden of stroke is increasing dramatically. Current epidemiological data indicate that 16.9million people suffer a stroke each year, which represents a global incidence of 258/100,000/year, with marked differences between high- and low-income countries, and an age-adjusted incidence 1.5 times higher in men than in women. Although primary prevention has contributed to a decrease in stroke incidence in high-income countries, the so-called 'epidemiological transition' has led to an increase in i...
Source: Revue Neurologique - January 12, 2016 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Temporal and Racial Trends in Post-Stroke Dementia in the "Stroke Buckle" of the United States (P1.099)
CONCLUSIONS: Over the last decade, incidence of PSD significantly increased in South Carolina. Black stroke patients had higher overall rates of PSD than whites, but this difference was largely driven by a comparatively greater burden of Non-AD dementia. Since Non-AD dementia is predominantly composed of vascular dementia, better vascular risk factor control may help bridge this racial disparity.Disclosure: Dr. Boan has nothing to disclose. Dr. Lackland has nothing to disclose. Dr. Feng has nothing to disclose. Dr. Voeks has nothing to disclose. Dr. Adams has received personal compensation for activities with Reach Call In...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Boan, A., Lackland, D., Feng, W., Voeks, J., Adams, R., Bachman, D., Ovbiagele, B. Tags: Neuroepidemiology: Aging and Dementia, Epilepsy, and Education Source Type: research

Determinants of post‐stroke cognitive impairment: analysis from VISTA
ConclusionsBesides well‐known determinants of PSCI such as age, stroke severity and the presence of vascular risk factors, also leg paralysis is associated with subsequent of PSCI up to 3 years after stroke.
Source: Acta Neurologica Scandinavica - July 14, 2016 Category: Neurology Authors: F. Arba, T. Quinn, G. J. Hankey, D. Inzitari, M. Ali, K. R. Lees, Tags: Original Article Source Type: research

Determinants of post ‐stroke cognitive impairment: analysis from VISTA
ConclusionsBesides well‐known determinants of PSCI such as age, stroke severity and the presence of vascular risk factors, also leg paralysis is associated with subsequent of PSCI up to 3 years after stroke.
Source: Acta Neurologica Scandinavica - July 12, 2016 Category: Neurology Authors: F. Arba, T. Quinn, G. J. Hankey, D. Inzitari, M. Ali, K. R. Lees, Tags: Original Article Source Type: research