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Condition: Dementia

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Total 4555 results found since Jan 2013.

Elderly Non-Demented Patients Have Better Outcome with Reperfusion Therapy Than Demented Patients Following Ischemic Stroke (P7.150)
Conclusion:Non-demented elderly patients perform nearly as well as younger patients with ischemic stroke when treated appropriately with IV/IA TPA. Reperfusion therapy should be considered in treating non-demented elderly patients in contrast to elderly patients with dementia.Disclosure: Dr. Duggal has nothing to disclose. Dr. Myers has nothing to disclose. Dr. Kim has nothing to disclose. Dr. Ahmed has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Duggal, N., Myers, T., Kim, J., Ahmed, I. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research

Elevated platelet‐derived growth factor AB/BB is associated with a lower risk of recurrent vascular events in stroke patients
ConclusionsHigher levels of PDGF‐AB/BB were independently associated with a lower risk of recurrent vascular events in a cohort of convalescent nondisabled stroke patients. Our findings suggest that PDGF‐AB/BB may potentially serve as a prognostic marker for outcomes pos‐ stroke and, if this result is validated in larger samples, a potential therapeutic target.
Source: International Journal of Stroke - August 1, 2014 Category: Neurology Authors: Kaavya Narasimhalu, Lu Ma, Deidre Anne De Silva, Meng‐Cheong Wong, Hui‐Meng Chang, Christopher Chen Tags: Research Source Type: research

White Matter Lesions Are Associated With Hospital Admissions Because of Hip-Fractures and Trauma After Ischemic Stroke Clinical Sciences
Conclusions— Patients with ischemic stroke and moderate-to-severe WMLs are at high risk, who experience serious traumatic injuries and especially hip-fractures requiring hospital treatment.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Sibolt, G., Curtze, S., Melkas, S., Pohjasvaara, T., Kaste, M., Karhunen, P. J., Oksala, N. K. J., Strandberg, T., Erkinjuntti, T. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Midlife Orthostatic Hypotension May Increase Risk of Dementia, Stroke
People with orthostatic hypotension (an excessive drop in blood pressure when standing up that can lead to dizziness and fainting) in midlife may be more likely than those without the condition to develop stroke and dementia later in life, according to astudy inNeurology.“The presence of orthostasis, especially in midlife, might identify individuals in whom more careful monitoring or risk factor management might be warranted,” wrote lead author Andreea Rawlings, Ph.D., of the Johns Hopkins Bloomberg School of Public Health and colleagues.These findings come from an analysis of data from 11,709 participants without a hi...
Source: Psychiatr News - July 30, 2018 Category: Psychiatry Tags: Alzheimer's Alzheimer's risk factors dementia dizziness orthostatic hypotension stroke Source Type: research

Incidence and risk factors of vascular dementia in Thai stroke patients
Stroke is one of the most common causes of disability worldwide. Besides physical disability in stroke survivors, vascular cognitive impairment (VCI) can prevent the patients from living independently. VCI or cognitive impairment from cerebrovascular disease is the second most common cause of dementia.1 VCI can follow ‘clinical’ stroke or occur in patients with no history of stroke. Those without history of clinical stroke should have sufficient cerebrovascular disease lesions detected by neuroimaging to cause cognitive impairment.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2020 Category: Neurology Authors: Pornpatr A. Dharmasaroja, Chanin Limwongse, Thammanard Charernboon Source Type: research

Analyzing Cost-Effectiveness of Allocating Neurointerventionist for Drive and Retrieve System for Patients with Acute Ischemic Stroke
The cost of stroke treatment accounts for approximately 6% of Japan's national medical expenditure,1 and stroke is the second most common condition, after dementia, that results in a requirement for long-term care. Thus, stroke has a significant impact on society.2 Cerebral infarction accounts for 60% or more of stroke cases.3 Systematic provision of highly equitable and efficient treatment for cerebral infarction is an important policy issue, such as the enactment of the Stroke and Cardiovascular Disease Control Act in December 2018 in Japan, as part of an effort to enhance provision of treatment for cerebral infarction.
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2021 Category: Neurology Authors: Yasuhiro Morii, Toshiya Osanai, Kensuke Fujiwara, Takumi Tanikawa, Kiyohiro Houkin, Songzi Gu, Katsuhiko Ogasawara Source Type: research

Alteration in brain functional connectivity in patients with post-stroke cognitive impairment during memory task: A fNIRS study
Post-stroke cognitive impairment (PSCI) refers to a spectrum of cognitive deterioration following stroke, ranging from mild cognitive impairment to dementia. Cortical plastic alterations associated with post-stroke cognitive impairment are not well documented. It is universally acknowledged as a prevalent and severe clinical syndrome that has an adverse influence on the prognosis of stroke patients [1]. Although PSCI is an umbrella term for a variety of pathological conditions, memory, and cognition impairments are the most troubling for stroke survivors and their carers [2].
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2023 Category: Neurology Authors: Ying Kong, Wenna Peng, Jing Li, Chunjiao Zhu, Changjie Zhang, Yongmei Fan Source Type: research

Blood-Brain Barrier Integrity Suffers Days After Ischemic Stroke Leading To Serious Complications
While the effects of acute stroke have been widely studied, brain damage during the subacute phase of stroke has been a neglected area of research. Now, a new study by the University of South Florida reports that within a week of a stroke caused by a blood clot in one side of the brain, the opposite side of the brain shows signs of microvascular injury. Stroke is a leading cause of death and disability in the United States, and increases the risk for dementia...
Source: Health News from Medical News Today - May 22, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Prestroke Dementia is Associated With Poor Outcomes After Reperfusion Therapy Among Elderly Stroke Patients
Conclusions: Among the elderly, prestroke dementia is a powerful independent predictor of in-hospital mortality after acute reperfusion therapy for stroke. Future investigations of thrombolysis outcomes in the elderly are warranted.
Source: Journal of Stroke and Cerebrovascular Diseases - December 19, 2011 Category: Neurology Authors: Katharina M. Busl, Raul G. Nogueira, Albert J. Yoo, Joshua A. Hirsch, Lee H. Schwamm, Natalia S. Rost Tags: Original Articles Source Type: research

Cognitive Dysfunction in Stroke Survivors: A Community-Based Prospective Study from Kolkata, India
The frequency of cognitive dysfunction among community stroke survivors (SS) is not known in India. This prospective study investigated the prevalence of poststroke mild cognitive impairment (psMCI) and poststroke dementia (psDem), the annual progression rate to dementia, and pertinent risk factors in a sample population of SS in Kolkata, India between September 2006 and July 2010. From a community-based stroke registry, 281 SS were assessed at baseline year after excluding attrition due to various causes. Validated cognitive tools were applied by trained field workers under supervision of a neuropsychologist. The assessme...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2012 Category: Neurology Authors: Sujata Das, Neelanjana Paul, Avijit Hazra, Malay Ghosal, Biman Kanti Ray, Tapas Kumar Banerjee, Prabir Burman, Shyamal Kumar Das Tags: Original Articles Source Type: research

Thrombolytic therapy for stroke in patients with preexisting cognitive impairment
Conclusions: Ischemic stroke patients with PSCI should receive rtPA if they are eligible. This conclusion cannot be extended to severe cognitive impairment or severe strokes. Classification of evidence: This study provides Class IV evidence that in patients with PSCI presenting with acute ischemic stroke, IV rtPA improves outcomes.
Source: Neurology - June 9, 2014 Category: Neurology Authors: Murao, K., Leys, D., Jacquin, A., Kitazono, T., Bordet, R., Bejot, Y., Kimura, K., Godefroy, O., Wakisaka, Y., Moulin, S., Ago, T., Sibon, I., Bombois, S., Mas, J.-L., Henon, H., Pasquier, F., Giroud, M., Cordonnier, C., Okada, Y., On behalf of the OPHELI Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, MCI (mild cognitive impairment), Infarction ARTICLE Source Type: research

Montreal Cognitive Assessment 5-Minute Protocol Is a Brief, Valid, Reliable, and Feasible Cognitive Screen for Telephone Administration Clinical Sciences
Conclusions— The MoCA 5-minute protocol is a free, valid, and reliable cognitive screen for stroke and transient ischemic attack. It is brief and highly feasible for telephone administration.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Wong, A., Nyenhuis, D., Black, S. E., Law, L. S. N., Lo, E. S. K., Kwan, P. W. L., Au, L., Chan, A. Y. Y., Wong, L. K. S., Nasreddine, Z., Mok, V. Tags: Behavioral/psychosocial - stroke Clinical Sciences Source Type: research

Impact of Bilingualism on Cognitive Outcome After Stroke Brief Reports
Conclusions— Our results suggest that bilingualism leads to a better cognitive outcome after stroke, possibly by enhancing cognitive reserve.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Alladi, S., Bak, T. H., Mekala, S., Rajan, A., Chaudhuri, J. R., Mioshi, E., Krovvidi, R., Surampudi, B., Duggirala, V., Kaul, S. Tags: Lifestyle, Behavioral/Psychosocial Treatment, Quality and Outcomes, Cognitive Impairment Brief Reports Source Type: research

Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia Clinical Sciences
Conclusions— Adherence to the American Heart Association’s ideal CVH factors and behaviors, particularly in midlife, may protect against cerebrovascular disease and dementia.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Pase, M. P., Beiser, A., Enserro, D., Xanthakis, V., Aparicio, H., Satizabal, C. L., Himali, J. J., Kase, C. S., Vasan, R. S., DeCarli, C., Seshadri, S. Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Cognitive Impairment Clinical Sciences Source Type: research

Design and Rationale for a Cognitive Outcome Substudy in Ischemic Stroke Patients with High Risk of Cerebral Hemorrhage
Cognitive impairment and dementia are common disabilities after stroke and are associated with increased risks of mortality and recurrent stroke. The prevention of dementia and preserving cognitive function are also important in stroke patients, but its strategy is not established yet. This PICASSO-COG (PreventIon of CArdiovascular events in iSchemic Stroke patients with high risk of cerebral hemOrrhage for reducing COGnitive decline) substudy aims to assess the effects of cilostazol and/or probucol on cognitive function.
Source: Journal of Stroke and Cerebrovascular Diseases - May 31, 2016 Category: Neurology Authors: Kyung-Ho Yu, Keun-Sik Hong, Mi-Sun Oh, Juneyoung Lee, Ji Sung Lee, Sun U. Kwon, PICASSO investigators Source Type: research