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Predicting new-onset post-stroke depression from real-world data using machine learning algorithm
DiscussionMachine learning models can provide as potential predictive tools for PSD and important factors are identified to alert clinicians for early detection of depression in high-risk stroke patients.
Source: Frontiers in Psychiatry - June 19, 2023 Category: Psychiatry Source Type: research

Cognitive dysfunction predicts worse health-related quality of life for older stroke survivors: a nationwide population-based survey in Taiwan.
CONCLUSION: Dementia and MCD strongly predicted worse overall and specific HRQoL dimensions, especially self-care and usual activities for older stroke survivors. PMID: 29266975 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - December 21, 2017 Category: Geriatrics Authors: Kuo LM, Tsai WC, Chiu MJ, Tang LY, Lee HJ, Shyu YL Tags: Aging Ment Health Source Type: research

Quality of Life and Psychological Distress of Caregivers' of Stroke People.
CONCLUSIONS: Caregivers of people with stroke experience mental disorders and burden negatively affecting their quality of life. Therefore, there is a need to implement strategies which should aim to the management of these problems for the welfare of both patients and their caregivers. PMID: 30315561 [PubMed - in process]
Source: Acta Neurologica Taiwanica - October 15, 2018 Category: Neurology Tags: Acta Neurol Taiwan Source Type: research

Patients with periodontitis are at a higher risk of stroke: A Taiwanese cohort study
CONCLUSION: Therefore, this study suggests a high risk of stroke in patients with periodontitis.PMID:36000972 | DOI:10.1097/JCMA.0000000000000797
Source: Atherosclerosis - August 24, 2022 Category: Cardiology Authors: Pei-Wei Hsu Yen-Wen Shen Syamsiah Syam Wen-Miin Liang Trong-Neng Wu Jui-Ting Hsu Lih-Jyh Fuh Source Type: research

Functional outcome prediction of ischemic stroke patients with atrial fibrillation accepting post-acute care training
ConclusionIn the current study, nearly half of the enrolled patients showed favorable functional recovery. The outcome assessments seem to correlate well with NIHSS and Barthel Index scores, rather than mRS. The anxiety/depression and usual activities domains of the EQ-5D results are associated with and have a great impact after the patients undertake the PAC rehabilitative strategy. Moreover, the variables obtained through carotid duplex and plaque index might also play a significant role in determining the patient's functional outcome.
Source: Frontiers in Neurology - September 23, 2022 Category: Neurology Source Type: research

IJERPH, Vol. 19, Pages 162: Increased Anxiety and Depression Symptoms in Post-Acute Care Patients with Stroke during the COVID-19 Pandemic
This study aimed to explore the quality and stability of post-acute care for patients with stroke, including their functional outcomes, mental health and medical care in Taiwan during the COVID-19 pandemic. In this retrospective case–control study—based on propensity score matching—we assessed 11 patients admitted during the pandemic period (in 2021) and 11 patients admitted during the non-pandemic period (in 2020). Functional outcomes, including the scores of the modified Rankin Scale, Barthel Index, EuroQoL-5 Dimension, Lawton–Brody instrumental activities of daily ...
Source: International Journal of Environmental Research and Public Health - December 24, 2021 Category: Environmental Health Authors: Hsiang-Yun Chou Yu-Chun Lo Ya-Wen Tsai Chia-Li Shih Chieh-Ting Yeh Tags: Article Source Type: research

CNS Summit 2017 Abstracts of Poster Presentations
Conclusion: This novel technology discriminates and quantifies subtle differences in behavior and neurological impairments in subjects afflicted with neurological injury/disease. KINARM assessments can be incorporated into multi-center trials (e.g., monitoring stroke motor recovery: NCT02928393). Further studies will determine if KINARM Labs can demonstrate a clinical effect with fewer subjects over a shorter trial period. Disclosures/funding: Dr. Stephen Scott is the inventor of KINARM and CSO of BKIN Technologies.   Multiplexed mass spectrometry assay identifies neurodegeneration biomarkers in CSF Presenter: Chelsky...
Source: Innovations in Clinical Neuroscience - November 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Drug Development General Genetics Medical Issues Neurology Patient Assessment Psychopharmacology Scales Special Issues Supplements Trial Methodology clinical trials CNS Su Source Type: research

Fecal incontinence epidemiology and help seeking among older people in Taiwan
ConclusionSelf‐reported FI is a prevalent condition with various etiologies among older people in Taiwan. Understanding the epidemiology and comorbidity of FI, and investigating the factors associated with help seeking, is beneficial in devising and implementing prevention and management strategies. Neurourol. Urodynam. © 2013 Wiley Periodicals, Inc.
Source: Neurourology and Urodynamics - September 1, 2013 Category: Urology & Nephrology Authors: Shiow‐Shiun Horng, Yiing‐Jenq Chou, Nicole Huang, Yi‐Ting Fang, Pesus Chou Tags: Original Clinical Article Source Type: research

Gender differences in presentation of behavioral and psychological symptoms in Alzheimer's disease in Taiwan.
CONCLUSIONS: The presentation of delusion and disinhibition in BPSD is associated with the female gender and staging of AD. Disinhibition was not necessarily associated with late stage of AD. PMID: 30912669 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - March 25, 2019 Category: Geriatrics Authors: Hsieh SW, Chen CH, Huang LC, Chang YH, Yang YH Tags: Aging Ment Health Source Type: research

C-Reactive Protein and Risk of Parkinson's Disease: A Systematic Review and Meta-Analysis
Conclusions: This meta-analysis revealed that PD is associated with an increase of CRP levels. CRP might be a risk factor for PD or PD leads to an inflammatory response. Introduction Parkinson's disease (PD) is one of the most complex neuro-degenerative disorders next to Alzheimer's disease. It is characterized by bradykinesia, tremor, rigidity, abnormal postural, and gait (1). PD has been recognized by the selective loss of dopaminergic neurons within the substantia nigra pars compacta, whereas the exact etiology remains elusive (2). Previously, multiple inferences have reviewed the environmental a...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately to severely acti...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

IJERPH, Vol. 19, Pages 5118: Association of Postpartum Depression with Maternal Suicide: A Nationwide Population-Based Study
Conclusion: PPD was associated with a significantly higher rate of suicide and a shorter time to suicide after childbirth. Younger age, winter, and subclinical depression and anxiety positively predicted suicide in the study cohort. To prevent maternal suicide, clinicians should be observant of subclinical depression and anxiety symptoms among patients.
Source: International Journal of Environmental Research and Public Health - April 23, 2022 Category: Environmental Health Authors: Yi-Liang Lee Yun Tien Yin-Shiuan Bai Chi-Kang Lin Chang-Sheng Yin Chi-Hsiang Chung Chien-An Sun Shi-Hao Huang Yao-Ching Huang Wu-Chien Chien Chieh-Yi Kang Gwo-Jang Wu Tags: Article Source Type: research

COVID-19 Can Increase Risk of Psychiatric Disorders for Up to Two Years
The increased risk of depression and anxiety that patients experience after developing COVID-19 typically subsides within two months, according to astudy published yesterday inThe Lancet Psychiatry. However, patients may have an elevated risk for developing other psychiatric and neurological conditions, such as psychosis, brain fog, and seizures, for up to two years after their infections.“The results have important implications for patients and health services as it suggests new cases of neurological conditions linked to COVID-19 infection are likely to occur for a considerable time after the pandemic has subsided,” s...
Source: Psychiatr News - August 18, 2022 Category: Psychiatry Tags: adults anxiety brain fog children COVID-19 delta dementia depression older adults omicron psychotic disorder seizures The Lancet Psychiatry Source Type: research