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Total 1205 results found since Jan 2013.

Primary Aldosteronism
Am Fam Physician. 2023 Sep;108(3):273-277.ABSTRACTPrimary aldosteronism is the underlying cause of hypertension in primary care settings in approximately 6% of cases, and it is even more common in patients with resistant hypertension. However, it is estimated that only about 2% of patients who have risk factors for primary aldosteronism have been formally tested or diagnosed. The first step in the diagnosis of primary aldosteronism is case detection and involves testing patients who are at risk, including individuals with resistant hypertension, as well as those with well-controlled hypertension and a first-degree relative...
Source: American Family Physician - September 19, 2023 Category: Primary Care Authors: Keith B Quencer J B Rugge Olga Senashova Source Type: research

Up-to-date advance in the relationship between OSA and stroke: a narrative review
CONCLUSION: Both the onset and recurrence of stroke closely correlated with OSA, but the specific mechanisms remain unclear. Further studies should be carried out to explore effective treatments in patients with stroke and OSA.PMID:37632670 | DOI:10.1007/s11325-023-02904-2
Source: Sleep and Breathing - August 26, 2023 Category: Sleep Medicine Authors: Bo Sun Qiyun Ma Jiani Shen Zili Meng Jing Xu Source Type: research

Who needs to be screened for primary aldosteronism?
J Formos Med Assoc. 2023 Aug 24:S0929-6646(23)00335-2. doi: 10.1016/j.jfma.2023.08.021. Online ahead of print.ABSTRACTThe prevalence of patients with primary aldosteronism (PA) is about 5%-15% in hypertensive patients, and it is common cause of secondary hypertension in clinical practice. Two major causes of PA are noted, namely bilateral adrenal hyperplasia and aldosterone-producing adenoma, and the general diagnosis is based on three steps: (1) screening, (2) confirmatory testing, and (3) subtype differentiation (Figure 1). The recommendation for screening patients is at an increased risk of PA, here we focus on which pa...
Source: J Formos Med Assoc - August 26, 2023 Category: General Medicine Authors: Wei-Chieh Huang Feng-Hsuan Liu Hao-Min Cheng Yi-Chun Tsai Yen-Ta Huang Tai-Shuan Lai Yen-Hung Lin Vin-Cent Wu Hsien-Li Kao Charles Jia-Yin Hou Kwan-Dun Wu Szu-Tah Chen Leay Kiaw Er Source Type: research

Up-to-date advance in the relationship between OSA and stroke: a narrative review
ConclusionBoth the onset and recurrence of stroke closely correlated with OSA, but the specific mechanisms remain unclear. Further studies should be carried out to explore effective treatments in patients with stroke and OSA.
Source: Sleep and Breathing - August 26, 2023 Category: Respiratory Medicine Source Type: research

The J-shape Association between Total Bilirubin and Stroke in Older Patients with Obstructive Sleep Apnea Syndrome: A Multicenter Study
ConclusionsBoth lower and higher bilirubin levels may increase the risk of stroke in older persons with OSAS, and there was a J-type dose-response relationship. The risk of stroke was lowest when the TBil level was approximately 11.5µmol/L.
Source: The Journal of Nutrition, Health and Aging - August 26, 2023 Category: Nutrition Source Type: research

Translation of obstructive sleep apnea pathophysiology and phenotypes to personalized treatment: a narrative review
Obstructive Sleep Apnea (OSA) arises due to periodic blockage of the upper airway (UA) during sleep, as negative pressure generated during inspiration overcomes the force exerted by the UA dilator muscles to maintain patency. This imbalance is primarily seen in individuals with a narrowed UA, attributable to factors such as inherent craniofacial anatomy, neck fat accumulation, and rostral fluid shifts in the supine posture. Sleep-induced attenuation of UA dilating muscle responsiveness, respiratory instability, and high loop gain further exacerbate UA obstruction. The widespread comorbidity profile of OSA, encompassing car...
Source: Frontiers in Neurology - August 24, 2023 Category: Neurology Source Type: research

Association Between Obstructive Sleep Apnea and Cardiovascular Events in Acute Coronary Syndrome Patients With or Without Revascularization 　- A Prospective Cohort Study
CONCLUSIONS: For patients with ACS, OSA was independently associated with higher risk of recurrent cardiovascular events among patients without revascularization but not among patients undergoing revascularization. The benefits of suitable OSA treatment for patients without revascularization need further investigation.PMID:37612051 | DOI:10.1253/circj.CJ-23-0164
Source: Circulation Journal - August 23, 2023 Category: Cardiology Authors: Ying Zhang Wen Hao Jingyao Fan Ruifeng Guo Hui Ai Bin Que Xiao Wang Jianzeng Dong Shaoping Nie Source Type: research

The multifaceted aspects of sleep and sleep-wake disorders following stroke
Rev Neurol (Paris). 2023 Aug 21:S0035-3787(23)00991-8. doi: 10.1016/j.neurol.2023.08.004. Online ahead of print.ABSTRACTSleep-wake disorders (SWD) are acknowledged risk factors for both ischemic stroke and poor cardiovascular and functional outcome after stroke. SWD are frequent following stroke, with sleep apnea (SA) being the most frequent SWD affecting more than half of stroke survivors. While sleep disturbances and SWD are frequently reported in the acute phase, they may persist in the chronic phase after an ischemic stroke. Despite the frequency and risk associated with SWD following stroke, screening for SWD remains ...
Source: Revue Neurologique - August 23, 2023 Category: Neurology Authors: S Baillieul C Denis L Barateau C Arquizan O Detante J-L P épin Y Dauvilliers R Tamisier Source Type: research

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