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Condition: Non-alcoholic Fatty Liver Diseases (NAFLD)

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Total 269 results found since Jan 2013.

Relationship of sitting time and physical activity with non-alcoholic fatty liver disease
Physical activity is well-recognized to reduce the incidence and mortality of various chronic diseases, including cardiovascular disease, diabetes, stroke and several types of cancer [1–3]. More than one half of the average person’s waking day involves sedentary activities associated with prolonged sitting such as watching TV and using the computer [4]. Recently, the deleterious effects of sedentary behavior regardless of additional physical activity have received a great deal of attention [5–8].
Source: Journal of Hepatology - September 14, 2015 Category: Gastroenterology Authors: Seungho Ryu, Yoosoo Chang, Hyun-Suk Jung, Kyung Eun Yun, Min-Jung Kwon, Yuni Choi, Chan-Won Kim, Juhee Cho, Byung-Seong Suh, Yong Kyun Cho, Eun Chul Chung, Hocheol Shin, Yeon Soo Kim Tags: Research Article Source Type: research

Association of whole blood viscosity with non-alcoholic fatty liver disease.
CONCLUSIONS: The findings showed that WBV at low shear stress is increased in NAFLD. Moreover, WBV at low shear stress is independently associated with NAFLD even after adjusting other cardiovascular risk factors. PMID: 26444605 [PubMed - as supplied by publisher]
Source: Clinical Hemorheology and Microcirculation - September 25, 2015 Category: Hematology Authors: Yu XY, Li Y, Liu T, Wang RT Tags: Clin Hemorheol Microcirc Source Type: research

Nonalcoholic Fatty Liver Disease and Mean Platelet Volume: A Systemic Review and Meta-analysis
Background: Nonalcoholic fatty liver disease (NAFLD) is linked to obesity, metabolic syndrome, and cardiovascular disease. Increased mean platelet volume (MPV), a marker of platelet activity, is associated with acute myocardial infarction, stroke, thrombosis, and increased mortality after myocardial infarction. The purpose of this study was to perform a meta-analysis to investigate the relationship between NAFLD and MPV. Methodology: A systematic search of MEDLINE (Ovid), PubMed, and CINAHL databases from 1950 to May 2014, complemented with manual review of references of published articles for studies comparing MPV in pati...
Source: Journal of Clinical Gastroenterology - December 9, 2015 Category: Gastroenterology Tags: LIVER, PANCREAS AND BILIARY TRACT: Original Articles Source Type: research

You Don't Need To Lose A Lot Of Weight To Start Seeing Health Benefits
This study clarifies conventional wisdom among obesity experts, who have traditionally advised patients to lose 5 to 10 percent of their body weight in order to improve blood pressure, cholesterol and blood sugar levels. But as anyone who has ever tried to lose weight can attest, there is a big difference between 5 percent and 10 percent.   "That’s a very vague, wide range," Klein said. "It’s much harder to achieve a 10 percent weight loss than it is to achieve a five percent weight loss." Klein said his study shows that even just a little bit of weight loss is enough to improve health, and that peopl...
Source: Science - The Huffington Post - February 23, 2016 Category: Science Source Type: news

Optimizing Acute Pain Management in the Obese Patient: Treatment and Monitoring Considerations
THE CHALLENGES OF PROVIDING SAFE AND EFFECTIVE pain management for patients with obesity are present throughout the perioperative setting. Obesity is associated with chronic medical comorbidities, such as coronary artery disease, stroke, chronic kidney disease, nonalcoholic fatty liver disease, and type 2 diabetes.1 Other obesity-associated comorbidities include breast, endometrial, ovarian, colorectal, esophageal, kidney, pancreatic, and prostate cancers, chronic back pain, and osteoarthritis.1 The demand for bariatric surgery has risen markedly in recent years with the total number of surgeries performed in the United St...
Source: Journal of PeriAnesthesia Nursing - February 27, 2016 Category: Nursing Authors: Maureen F. Cooney Tags: Pain Care Source Type: research

Visceral Fat Triggers Heart Disease
I tell my patients to avoid drinking soda not just because they make you fat. Each sip of soda affects your health. Soda puts you at risk for health problems like metabolic syndrome. This is a collection of symptoms that can lead to diabetes, heart disease and other chronic diseases, like cancer. Soft drinks are the beverage of choice for millions of Americans. The latest research now reveals that sodas are a major cause of visceral fat — the deadliest kind of fat you can have, inflaming your tissues, rotting your blood vessels and upsetting your body chemistry. In a minute I’m going to tell you about a great healthy ...
Source: Al Sears, MD Natural Remedies - February 29, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Heart Health heart disease metabolic syndrome Visceral Fat Source Type: news

Chitotriosidase: A New Inflammatory Marker in Diabetic Complications
Chitotriosidase (CHIT1) belongs to chitinase family. So far this enzyme has been the best investigated human chitinase regarding its biological activity and association with various disorders. In a healthy population, CHIT1 activity is very low and originates in the circulating polymorphonuclear cells. Conversely, during the development of acute/chronic inflammatory disorders, the enzymatic activity of CHIT1 increases significantly. Recently, CHIT1 has also been involved in the pathogenesis of diabetes mellitus (DM). Mounting evidence from experimental studies revealing the increase of CHIT1 levels in pathological conditio...
Source: Pathobiology - April 26, 2016 Category: Pathology Source Type: research

Added Sugars and Cardiovascular Disease Risk in Children: A Scientific Statement From the American Heart Association.
CONCLUSIONS: Associations between added sugars and increased cardiovascular disease risk factors among US children are present at levels far below current consumption levels. Strong evidence supports the association of added sugars with increased cardiovascular disease risk in children through increased energy intake, increased adiposity, and dyslipidemia. The committee found that it is reasonable to recommend that children consume ≤25 g (100 cal or ≈6 teaspoons) of added sugars per day and to avoid added sugars for children <2 years of age. Although added sugars most likely can be safely consumed in low amounts as ...
Source: Circulation - August 21, 2016 Category: Cardiology Authors: Vos MB, Kaar JL, Welsh JA, Van Horn LV, Feig DI, Anderson CA, Patel MJ, Cruz Munos J, Krebs NF, Xanthakos SA, Johnson RK, American Heart Association Nutrition Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Clinical Cardiology Tags: Circulation Source Type: research

Nonalcoholic Fatty Liver Disease and the Risk of Clinical Cardiovascular Events: A Systematic Review and Meta-Analysis
Conclusion NAFLD patients have a significantly higher risk for clinical CVE compared to those without. These results need to be confirmed in large prospective studies.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 15, 2016 Category: Endocrinology Source Type: research

A machine learning approach to measure and monitor physical activity in children
Publication date: 8 March 2017 Source:Neurocomputing, Volume 228 Author(s): Paul Fergus, Abir J. Hussain, John Hearty, Stuart Fairclough, Lynne Boddy, Kelly Mackintosh, Gareth Stratton, Nicky Ridgers, Dhiya Al-Jumeily, Ahmed J. Aljaaf, Jenet Lunn The growing trend of obesity and overweight worldwide has reached epidemic proportions with one third of the global population now considered obese. This is having a significant medical impact on children and adults who are at risk of developing osteoarthritis, coronary heart disease and stroke, type 2 diabetes, cancers, respiratory problems, and non-alcoholic fatty liver disease...
Source: Neurocomputing - January 16, 2017 Category: Neuroscience Source Type: research

What Are Endoscopic Bariatric Therapies?
The high prevalence of overweight and obesity in the United States negatively affects the health of the population. Obesity increases the risk of various diseases, including diabetes mellitus, hypertension, coronary heart disease, sleep apnea, stroke, gatroesophageal reflux disease, gall bladder disease, certain types of malignancy, and non-alcoholic fatty liver diseases.1,2 Reducing obesity in the United States has become a public health priority.1,2 Current approaches to therapeutic weight loss include dietary approaches, lifestyle intervention, pharmacology, and surgery.
Source: Journal of the American Dietetic Association - January 25, 2017 Category: Nutrition Authors: Wendy Marcason Tags: From the Academy Source Type: research

Pathophysiology of obstructive sleep apnea syndrome and its cardiometabolic consequences.
Abstract Obstructive sleep apnoea syndrome (OSAS) is characterized by recurrent partial or complete pharyngeal collapses during sleep. The pathophysiology of OSAS is complex and multifactorial. Factors influencing upper airway patency include a reduction in upper airway dimensions that can result from both anatomical and functional alterations (obesity, fluid shift or maxillo-facial structural changes), and increased pharyngeal collapsibility owing to reduced neuromuscular compensation and lack of the pharyngeal protective reflex during sleep. Severe OSAS is associated with a high cardiometabolic risk. Obstructive...
Source: Presse Medicale - January 22, 2017 Category: Journals (General) Authors: Destors M, Tamisier R, Galerneau LM, Lévy P, Pepin JL Tags: Presse Med Source Type: research

Adiponectin, lipids and atherosclerosis
Purpose of review: Adiponectin is an adipokine with anti-inflammatory, antioxidant, antiatherogenic, pro-angiogenic, vasoprotective and insulin-sensitizing properties. Several factors may influence adiponectin levels, such as genetic polymorphisms, obesity / body fat distribution, diet and exercise as well as cardiovascular risk factors such as sleep deprivation and smoking as well as medications. Adiponectin has been proposed as a potential prognostic biomarker and a therapeutic target in patients with cardiometabolic diseases. Recent findings: This narrative review discusses the associations of adiponectin with obesity-...
Source: Current Opinion in Lipidology - July 14, 2017 Category: Lipidology Tags: HYPERLIPIDAEMIA AND CARDIOVASCULAR DISEASE: Edited by Paul N. Durrington Source Type: research

Weight Loss in Italy?
One of the women I work with wanted to know about the new diet drug called Belviq. The FDA is always approving a new “miracle” weight-loss pill, only to recall it a few years later. To date, at least 34 diet drugs have been taken off the market. Diet pills cause all kinds of problems — heart attack, stroke and psychiatric disorders. And Belviq isn’t any different. Some of its side effects include suicidal thoughts, a racing heartbeat, hallucinations and more… The European Union banned Belviq. The reason? It causes cancer in animals.  And here’s the real irony… Clinical trials found ...
Source: Al Sears, MD Natural Remedies - October 19, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

Vitamin D, Cardiovascular Disease and Risk Factors.
Authors: Skaaby T, Thuesen BH, Linneberg A Abstract Observational studies have suggested a possible protective role of vitamin D on the cardiovascular system. The available evidence does not support either cardiovascular benefits or harms of vitamin D supplementation. This chapter provides an overview and discussion of the current knowledge of vitamin D effects from a cardiovascular health perspective. It focuses on vitamin D in relation to cardiovascular disease, i.e. ischemic heart disease, and stroke; the traditional cardiovascular risk factors hypertension, abnormal blood lipids, obesity; and the emerging risk ...
Source: Advances in Experimental Medicine and Biology - November 12, 2017 Category: Research Tags: Adv Exp Med Biol Source Type: research