Treating Acute Medical Conditions Outside the Hospital: Streamlining Care During a Pandemic
No abstract available (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: LETTERS TO THE EDITOR Source Type: research

Impact of Tilt-down Positioning Compared With Left Lateral Positioning on Ease of Colonoscope Insertion During Colonoscopy
No abstract available (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: LETTERS TO THE EDITOR Source Type: research

Inhibitors of the Janus Kinases: A New Oral Treatment Option for Ulcerative Colitis
No abstract available (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: LETTERS TO THE EDITOR Source Type: research

Regular Statin Use and Incidence of Postendoscopic Retrograde Cholangiopancreatography Pancreatitis
Conclusions: Regular statin use was not shown to be protective against PEP. A further investigation is warranted before this medication is tested in prospective randomized trials. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Improving Communication in Outpatient Consultations in People With Cirrhosis: The Development of a Question Prompt List (QPL)
Conclusions: A QPL, suitable for use in patients with liver cirrhosis attending hepatology outpatient clinics, has been developed and piloted. The QPL seems to be feasible to use and acceptable to patients and clinicians. Further work is needed to evaluate its effectiveness and to determine optimum delivery in clinical practice. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Accuracy of Noninvasive Fibrosis Scores to Detect Advanced Fibrosis in Patients With Type-2 Diabetes With Biopsy-proven Nonalcoholic Fatty Liver Disease
Conclusions: In this large cohort of adult patients with T2D and NAFLD, commonly used fibrosis scores had reasonable specificity, but poor sensitivity for detecting AF in diabetics. The development of reliable biomarkers for NAFLD/NASH in diabetics is urgently needed. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Poor Graft and Patient Survival After Liver Transplantation in Sarcoidosis
We examined the clinical characteristics and post-LT outcomes of patients with sarcoidosis using the United Network for Organ Sharing database from 1985 to 2016 and compared them to patients (entire cohort as well as age, gender, and year of LT-matched counterparts) with primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC). For the matched design, a conditional logistic regression was used for categorical variables and marginal generalized estimating equation regression models for continuous variables. Survival functions were constructed using the Kaplan-Meier estimator. Results: A total of 206 pat...
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Stop Blaming the Weatherman! A Retrospective Study of Endoscopy Show Rates at a Midwest Urban Safety-Net Hospital
Background: Weather patterns are well-known to affect human health and behavior and are often arbitrarily blamed for high no-show rates (NSRs). The NSR for outpatient gastrointestinal procedures ranges from 4% to 41% depending on the population and procedure performed. Identifying potential causes will allow for the optimization of endoscopy resource utilization. Aim: The aim of this study was to evaluate the effects of a day of the year and weather conditions have on NSRs for outpatient endoscopic procedures at a safety-net hospital in Cleveland, Ohio, United States. Methods: A 12-month, retrospective cohort study...
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Gastrectomy Versus Endoscopic Resection for Patients With Early-stage Gastric Adenocarcinoma: A Population-based Propensity Matching Study
Conclusion: The long-term prognosis appears equivalent t in patients with endoscopic resection and gastrectomy. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Deprescribing Proton Pump Inhibitors in an Academic, Primary Care Clinic: Quality Improvement Project
Goal: The goal of this study was to reduce the percentage of inappropriately prescribed proton pump inhibitors (PPIs) in patients aged 50 and older from 80% (baseline) to 60% within 12 months in an academic, internal medicine clinic. Background: The use of PPIs has increased drastically worldwide. Internal medicine clinic patients had inappropriate use of PPIs for an average of 4 to 5 years. Study: A multidisciplinary quality improvement team used the Plan-Do-Study-Act Model of health care improvement and performed a root cause analysis to identify barriers to inappropriate use of PPIs. The outcome measure was the ...
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Development of a Preliminary Question Prompt List as a Communication Tool for Adults With Gastroesophageal Reflux Disease: A Modified Delphi Study
Conclusions: A preliminary GERD-specific QPL, the first of its kind, was developed by esophageal experts. Modification after more patient consultation and feedback is planned in subsequent versions to create a GERD-QPL for eventual use in clinical gastroenterology. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Understanding Gaps in the Hepatocellular Carcinoma Cascade of Care: Opportunities to Improve Hepatocellular Carcinoma Outcomes
Hepatocellular carcinoma (HCC) is a leading cause of morbidity and mortality. Existing studies have highlighted significant disparities in HCC outcomes, particularly among vulnerable populations, including ethnic minorities, safety-net populations, underinsured patients, and those with low socioeconomic status and high risk behaviors. The majority of these studies have focused on HCC surveillance. Although HCC surveillance is one of the most important first steps in HCC monitoring and management, it is only one step in the complex HCC cascade of care that evolves from surveillance to diagnosis and tumor staging that leads ...
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: CLINICAL REVIEWS Source Type: research

Hepatic Injury in Patients With COVID-19
Conclusions: Liver injury is highly prevalent in patients that present with COVID-19. Since the liver is one of the most affected organs outside of the respiratory system in COVID-19, more intensive surveillance is warranted for severe cases, particularly among those with pre-existing advanced liver disease. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: CLINICAL REVIEWS Source Type: research

Personal Protective Equipment for Endoscopy in Low-Resource Settings During the COVID-19 Pandemic: Guidance From the World Gastroenterology Organisation
Performance of endoscopic procedures is associated with a risk of infection from COVID-19. This risk can be reduced by the use of personal protective equipment (PPE). However, shortage of PPE has emerged as an important issue in managing the pandemic in both traditionally high and low-resource areas. A group of clinicians and researchers from thirteen countries representing low, middle, and high-income areas has developed recommendations for optimal utilization of PPE before, during, and after gastrointestinal endoscopy with particular reference to low-resource situations. We determined that there is limited flexibility wi...
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: WGO GUIDELINE Source Type: research

Comparative Efficacy of Drugs for the Treatment of Chronic Constipation: Quantitative Information for Medication Guidelines
Conclusions: The data provided in this study may be a valuable supplement to the medication guidelines for the treatment of chronic constipation. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: ONLINE ARTICLE: Original Article Source Type: research

World Gastroenterology Organisation (WGO) News and Events
No abstract available (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - October 9, 2020 Category: Gastroenterology Tags: WGO NEWS Source Type: research

HBeAg Negativity Is Associated With More Advanced Liver Fibrosis in Patients With Chronic Hepatitis B: A Propensity Score-Matching Analysis
Background: Serum hepatitis B e antigen (HBeAg) status is associated with the progression of chronic hepatitis B (CHB). The authors aimed to investigate the relationship between HBeAg status and liver pathology in CHB patients. Methods: A total of 683 treatment-naive CHB patients who had undergone liver biopsy were retrospectively enrolled from 2 medical centers. Propensity score-matching (PSM) method was performed to adjust the imbalance of baseline confounders between HBeAg-positive and HBeAg-negative CHB patients. Results: HBeAg-negative CHB patients (n=338) exhibited more advanced liver fibrosis than HBeAg-posi...
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Article Source Type: research

Successful Infliximab Treatment is Associated With Reversal of Clotting Abnormalities in Inflammatory Bowel Disease Patients
Conclusions: Control of inflammation using infliximab most strongly reduced those parameters that are associated with a higher risk of venous thromboembolism. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Adverse Events After Inpatient Colonoscopy in Octogenarians: Results From the National Inpatient Sample (1998-2013)
Conclusions: There seems to be a higher risk of adverse GI-related events after colonoscopy in octogenarians as compared with the general population. Furthermore, occurrence of adverse GI-related events increased the risk of mortality among octogenarians regardless of comorbid status. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Efficacy and Cost-effectiveness Comparison of 10-Day, 14-Day Sequential Versus 14-Day Triple Therapies for Treating Helicobacter pylori Infection in Egyptian Patients
Conclusions: Sequential therapies for 10 or 14 days are more cost-effective than standard TT, with 14-day ST being the most cost-effective. Accordingly, ST might replace TT as a first-line treatment for H. pylori infection in Egyptian patients. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Factors Associated With Hospital Admissions and Readmissions in Patients With Gastroparesis Using the Nationwide Readmission Database
Conclusions: Use of the Nationwide Readmission Database (NRD) allows better understanding of gastroparesis admissions and readmissions. Average hospital stay was 5.4 days with 0.4% mortality rate. Overall 30-day readmission rate was 6.2%. Higher LOS, drug abuse, and marijuana use increased the 30-day readmission rate. Diabetes, hypertension, and older age were associated with lower readmissions. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Sex Differences in the Risk of Barrett’s Esophagus Associated With the Metabolic Effects of Obesity
Conclusion: Hyperinsulinemia, insulin resistance, and the MetS are associated with the risk of BE in males but not females, suggesting these factors may contribute to the higher prevalence of BE in males. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Novel Calculators for Risk Stratification in Hepatocellular Carcinoma: A Concise Review
Among clinicians, the users of medical calculators have expanded in recent years to an unprecedented number. The usefulness of some of these calculators is sometimes debatable, and experienced professionals may at times be right in avoiding their use; however, many may simply be unaware of the very existence of medical calculators applicable to their field of interest. The authors felt that this latter scenario might possibly apply to hepatocellular carcinoma (HCC). Hence, the authors concisely reviewed 10 free online medical calculators proposed in the last 8 years, categorizing them on the basis of the purpose for which ...
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: CLINICAL REVIEWS Source Type: research

Cannabinoids: A Guide for Use in the World of Gastrointestinal Disease
This article hopes to create an overview of current research on cannabinoids and the ECS, detail the potential advantages and pitfalls of their use in GI diseases, and explore possible future developments in this field. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: CLINICAL REVIEWS Source Type: research

Bouveret Syndrome: A Systematic Review of Endoscopic Therapy and a Novel Predictive Tool to Aid in Management
Background and Goals: Bouveret syndrome is characterized by gastroduodenal obstruction caused by an impacted gallstone. Current literature recommends endoscopic therapy as the first line of intervention despite significantly lower success rates compared with surgery. The lack of treatment efficacy studies and the paucity of clinical guidelines contribute to current practices being arbitrary. The aim of this systematic review was to identify factors that predict outcomes of endoscopic therapy. Subsequently, a predictive tool was devised to predict the success of endoscopic therapy and recommendations were proposed to impr...
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: CLINICAL REVIEWS Source Type: research

World Gastroenterology Organisation Global Guidelines: Management of Strongyloidiasis February 2018—Compact Version
Strongyloides stercoralis is a soil-transmitted helminth, but it has a unique life cycle that can be completed in the human host, in a process known as autoinfection. Worldwide, the burden of disease is substantial (300 to 400 million infections). Strongyloidiasis is mainly prevalent in the tropics and subtropics, but there is as yet no global public health strategy for controlling the parasite. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: WGO GUIDELINE Source Type: research

Assessment of Gastric Emptying Times Between Pediatrics and Adults With Cyclic Vomiting Syndrome
Conclusions: (1) GE is predominantly rapid at 2 hours in pediatrics and adults with CVS. (2) Rapid GE seems to increase with age. (3) Current guidelines do not recommend GE in the initial management, however, further studies may play a role to help differentiate CVS from other functional gastric disorders. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: ONLINE ARTICLES: Original Articles Source Type: research

Serum Levels of Insulin-like Growth Factor 1 and Insulin-like Growth Factor–binding Protein 2 as a Novel Biomarker in the Detection of Pancreatic Adenocarcinoma
Background: Insulin-like growth factor 1 (IGF-1) and insulin-like growth factor–binding protein 2 (IGFBP-2) are proteins that belong to the IGF axis, which is involved in glucose and lipid metabolism and may as well promote carcinogenesis. Goals: The aim of this study was to evaluate the serum concentration levels of IGF-1 and IGFBP-2 in patients with newly diagnosed pancreatic adenocarcinoma (PDAC) to verify their possible role in the diagnosis of the disease. Study: The study included 69 patients with PDAC and 20 healthy controls. The concentrations of IGF-1 and IGFBP-2 were estimated by means of ELISA. The...
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: ONLINE ARTICLES: Original Articles Source Type: research

World Gastroenterology Organisation (WGO) News and Events
No abstract available (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - September 10, 2020 Category: Gastroenterology Tags: WGO NEWS Source Type: research

Thromboelastography Better Reflects Hemostatic Abnormalities in Cirrhotics Compared With the International Normalized Ratio
Conclusions: Although cirrhotics had TEG parameters within normal ranges, there was a propensity for decreased clot formation as liver function worsened. Importantly, the INR did not correlate with TEG parameters in cirrhotic patients, and given the precarious hemostatic balance in these patients, a TEG may be a better predictor of bleeding risk. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Statin Use is Protective Against Hepatocellular Carcinoma in Patients With Nonalcoholic Fatty Liver Disease: A Case-control Study
Conclusions: In a cohort of NAFLD-HCC patients, statin use was protective against HCC, while hypertension conferred an increased risk. Visceral adiposity at baseline was not a risk factor, but was higher in male patients before HCC development, declining in the majority by HCC diagnosis. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

IBD in India: Similar Phenotype but Different Demographics Than the West
Conclusions: This is the largest cohort of persons with IBD reported from Asia. Although there are several demographic differences between persons with IBD from India compared with the West, the phenotypes of the disease are not highly different. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Comparison of Disease-related Knowledge of Patients With Inflammatory Bowel Disease Between the West and the East Using an Updated Questionnaire (IBD-KNOW)
Goals: The study aimed to compare the level and characteristics of disease-related knowledge of patients with inflammatory bowel disease (IBD) between the West and the East using an international version of a questionnaire regarding knowledge of inflammatory bowel disease (IBD-KNOW). Background: The authors recently developed a new questionnaire regarding IBD-KNOW, which showed excellent test characteristics in Korea. Study: The IBD-KNOW questionnaire was administered to 100 patients with IBD from tertiary referral hospitals in the United States and Korea. Scores were calculated and compared between US and Korean p...
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Demographics Predict Stage III/IV Colorectal Cancer in Individuals Under Age 50
Conclusions: Among individuals with early-onset CRC, younger age, Asian, black, or Pacific Islander race, and being nonpartnered were predictors of advanced disease at presentation. Colon cancer was more likely to be diagnosed at stage IV than rectal cancer. Patient characteristics associated with advanced CRC may indicate both differences in tumor biology and disparities in health care access. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

An Evidence-based Approach Towards Targeted Patient Education to Improve Bowel Preparation for Colonoscopy
Conclusions: Poor bowel preparation is associated with specific risk factors. Identifying and specifically targeting education at patients with these risk factors appears to facilitate more efficient use of education resources in endoscopy. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Long-Term Efficacy and Safety of Fecal Microbiota Transplantation for Treatment of Recurrent Clostridioides difficile Infection
Conclusions: In this largest and longest study to date on efficacy and safety after FMT for treatment of rCDI, we found that the majority of patients experienced long-term cure. Although a number of new conditions developed post-FMT, there was no clustering of diseases associated with dysbiosis. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Helicobacter pylori Infection and the Development of Advanced Colorectal Neoplasia
Conclusions: In a cohort study, H. pylori infection was associated with an increased risk of AN development. This association was consistent in both the serological and histologic assessment of H. pylori infection. Prospective studies are necessary to determine whether H. pylori eradication can reduce the risk of colorectal neoplasia. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Advances in Imaging of Diffuse Parenchymal Liver Disease
There are>1.5 billion people with chronic liver disease worldwide, causing liver diseases to be a significant global health issue. Diffuse parenchymal liver diseases, including hepatic steatosis, fibrosis, metabolic diseases, and hepatitis cause chronic liver injury and may progress to fibrosis and eventually hepatocellular carcinoma. As early diagnosis and treatment of these diseases impact the progression and outcome, the need for assessment of the liver parenchyma has increased. While the current gold standard for evaluation of the hepatic parenchymal tissue, biopsy has disadvantages and limitations. Consequently, no...
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: CLINICAL REVIEWS Source Type: research

Sorafenib Plus Hepatic Arterial Infusion Chemotherapy in Advanced Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Background and Aim: The clinical utility of sorafenib plus hepatic arterial infusion chemotherapy (SoraHAIC) in advanced hepatocellular carcinoma (HCC) patients remains unclear. We, therefore, conducted the current meta-analysis to systematically evaluate the efficacy and safety of SoraHAIC therapy on major outcomes with advanced HCC patients. Methods: A systematic search of The Cochrane Library, PubMed, and Embase databases was performed. The major outcomes in patients with advanced HCC were divided into SoraHAIC group and sorafenib group, which included overall response rate, overall survival, progressive disease, a...
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: CLINICAL REVIEWS Source Type: research

Nocturnal Gastroesophageal Reflux Disease (GERD) and Sleep: An Important Relationship That Is Commonly Overlooked
Gastroesophageal reflux disease (GERD) is a prevalent, chronic medical condition that affects 13% of the adult population globally at least once a week. Sleep disturbances are frequently encountered in up to 25% of the GERD patients, likely due to nocturnal gastroesophageal reflux (GER). With advance in diagnostic techniques allowing for an improved understanding of involved physiological mechanisms of nocturnal reflux, there is growing evidence of a bidirectional relationship between GERD and sleep disturbances. Furthermore, nocturnal GER is associated with more complicated GERD. Obstructive sleep apnea (OSA) and GERD als...
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: CLINICAL REVIEWS Source Type: research

Serum HBV RNA Dynamic and Drug Withdrawal Predictor Value in Patients With Chronic HBV Infection on Long-term Nucleos(t)ide Analogue (NA) Therapy
Conclusions: In the long-term antiviral process, both serum HBV RNA and DNA levels declined significantly. EOT serum HBV RNA negativity was not an independent drug withdrawal marker, but can complement the HBsAg titer to monitor drug withdrawal in CHB patients on long-term NA therapy. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: ONLINE ARTICLE: Original Article Source Type: research

World Gastroenterology Organisation (WGO) News and Events
No abstract available (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - August 13, 2020 Category: Gastroenterology Tags: WGO NEWS Source Type: research

Longitudinal Change in Simple Scores Identifies Fibrosis Status in People With Nonalcoholic Fatty Liver Disease
No abstract available (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - July 30, 2020 Category: Gastroenterology Tags: LETTER TO THE EDITOR Source Type: research

Balloon-Occluded Retrograde Transvenous Obliteration (BRTO) Versus Transjugular Intrahepatic Portosystemic Shunt (TIPS) for Treatment of Gastric Varices Because of Portal Hypertension: A Systematic Review and Meta-Analysis
Background: Although gastric variceal (GV) bleeding is less common than esophageal variceal bleeding, the severity of GV bleeding is often greater with higher morbidity and mortality rates. Minimally invasive endovascular treatments such as balloon-occluded retrograde transvenous obliteration (BRTO) and transjugular intrahepatic portosystemic shunt (TIPS) have been used for the management of GVs with varying results, and individual and institutional differences exist in the use of BRTO and TIPS. We performed a systematic review and meta-analysis to compare the feasibility, efficacy, and safety of BRTO and TIPS for the tr...
Source: Journal of Clinical Gastroenterology - July 30, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Increased Posttransplant Mortality for Autoimmune Hepatitis Compared With Other Autoimmune Liver Diseases
Conclusion: As prior studies have shown the similar risk of disease recurrence in AIH and PSC, our study indicates at least part of the increased posttransplant mortality in AIH may be due lower retransplantation rate in this population. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - July 30, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

A Patient-Centered Hepatitis B Virus (HBV) Educational Intervention Improves HBV Care Among Underserved Safety-Net Populations
Goals: To evaluate the impact of a prospective patient-centered hepatitis B virus (HBV) educational intervention on improving HBV care. Background: Improving patients’ HBV knowledge has the potential to improve adherence to HBV monitoring and management, particularly among underserved safety-net populations. Methods: Consecutive chronic HBV adults at a single-center safety-net liver clinic were recruited from July 2017 to July 2018 to evaluate the impact of an in-person, language concordant formal HBV educational intervention on improvements in HBV knowledge and HBV management: appropriate HBV clinic follow-u...
Source: Journal of Clinical Gastroenterology - July 30, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Radiologic Nonalcoholic Fatty Liver Disease Increases the Risk of Hepatocellular Carcinoma in Patients With Suppressed Chronic Hepatitis B
This study evaluated the association between NAFLD and the risk of HCC in patients whose hepatitis B virus (HBV) was well controlled. Study: This study included consecutive CHB patients whose serum HBV DNA levels were continuously suppressed (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - July 30, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Clinical Characteristics of Different Primary Constipation Subtypes in a Chinese Population
Conclusion: Patients with FDD suffer more severe constipation symptoms and have a lower QOL than patients in other CC subgroups. FDD and NTC patients’ QOL is mainly linked to constipation symptoms, while that of slow transit constipation is mainly related to mental states such as anxiety and depression. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - July 30, 2020 Category: Gastroenterology Tags: LIVER, PANCREAS & BILIARY TRACT: Original Articles Source Type: research

Effect of a Gluten-free Diet on Quality of Life in Patients With Nonclassical Versus Classical Presentations of Celiac Disease
Conclusions: Despite QOL at diagnosis being higher in those with nonclassical CD versus lower in those with classical CD, both groups had improved QOL and achieved a similar QOL after following a GFD. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - July 30, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research

Interaction Between Ethnicity and Helicobacter pylori Infection in the Occurrence of Reflux Disease
Conclusions: Gastric H. pylori infection, ethnicity, gender, and age all influence the occurrence of Barrett metaplasia, and reflux esophagitis. (Source: Journal of Clinical Gastroenterology)
Source: Journal of Clinical Gastroenterology - July 30, 2020 Category: Gastroenterology Tags: ALIMENTARY TRACT: Original Articles Source Type: research