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Total 287 results found since Jan 2013.

Pulmonary Embolism in Ischemic Stroke: Clinical Presentation, Risk Factors, and Outcome Stroke
Conclusions In this large cohort study, PE occurred in nearly 1% of AIS patients. PE was more common in patients with severe stroke, history of cancer, previous DVT/PE or acute DVT and associated with lower short- and long-term survival, greater disability, and longer length of stay.
Source: JAHA:Journal of the American Heart Association - November 25, 2013 Category: Cardiology Authors: Pongmoragot, J., Rabinstein, A. A., Nilanont, Y., Swartz, R. H., Zhou, L., Saposnik, G., The Investigators of the Registry of the Canadian Stroke Network (RCSN) and University of Toronto Stroke Program for the Stroke Outcomes Research Canada (SORCan [www. Tags: Stroke Source Type: research

Understanding Coordinator Roles in Acute Stroke Care: A National Survey
Globally, stroke is a major contributor to death and disability.1 Evidence-based care in hospital after an acute stroke ensures improved survival and reduced disability, but care quality can vary.2,3 Clinical coordinators have an essential role in improving best-practice in trauma, cancer, diabetes, and heart failure conditions.4-7 Within stroke, coordinator roles are not new; in 1970, a study outlining the ‘Stroke Team’ model was published, which included a physician, nurse-coordinator and physical therapist.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2021 Category: Neurology Authors: Tara Purvis, Sandy Middleton, Anne W. Alexandrov, Monique F. Kilkenny, Skye Coote, Sarah Kuhle, Dominique A. Cadilhac Source Type: research

Is the Intensity or Duration of Treadmill Training Important for Stroke Patients? A Meta-Analysis
Stroke, the third highest cause of death after cancer and cardiac diseases, is a strong cause of adult disability in most countries. Therefore, the aim of the current meta-analysis was to examine the most effective intensity and duration of treadmill training on motor performance in stroke subjects.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2017 Category: Neurology Authors: Sadegh Abbasian, Mahsa Rastegar MM Tags: Review Article Source Type: research

Antithrombotic Therapy Strategy for Cancer-Associated Ischemic Stroke: A Case Series of 26 Patients
The risk of complications from thromboembolism is increased for patients with malignancy. Cancer-associated stroke is also a serious issue with regard to the management of patients with cancer because stroke incidence often causes disabilities that affect daily life and cancer treatment strategy.
Source: Journal of Stroke and Cerebrovascular Diseases - May 17, 2018 Category: Neurology Authors: Hiroyuki Naito, Tomohisa Nezu, Naohisa Hosomi, Shiro Aoki, Hiroki Ueno, Kazuhide Ochi, Hirofumi Maruyama Tags: Case Studies Source Type: research

Effects of l-Carnitine Supplementation, Botulinum Neurotoxin Injection, and Rehabilitation for a Chronic Stroke Patient
Botulinum neurotoxin injection therapy and rehabilitation have been conducted for stroke patients to reduce the spasticity of their affected limbs and improve their walking ability and daily living. Furthermore, their disability was reported to be related to muscle wasting. Supplementation of l-carnitine was reported to improve physical endurance and was used to treat sarcopenia in, for example, patients with cancer. Here, we report a case of chronic stroke with muscle wasting in a patient with improved walking endurance by l-carnitine supplementation, botulinum neurotoxin injection, and rehabilitation.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2018 Category: Neurology Authors: Satoshi Endo, Tadashi Takahashi, Masaya Sato, Yoshinori Noya, Masayoshi Obana Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

A Post-hoc Study of D-Amino Acid Oxidase in Blood as an Indicator of Post-stroke Dementia
In conclusion, our data support that plasma DAO levels were increased in PSD patients and correlated with brain WMH, independent of age, gender, hypertension, and renal function. Plasma DAO levels may therefore aid in PSD diagnosis. Introduction Stroke is a risk factor for both vascular dementia and Alzheimer's disease (1, 2). Functional recovery develops over the course of 26 weeks after a stroke (3), but the survivors are often left with disabilities. In addition to the sequelae of acute neuronal damage, the 1-year post-stroke dementia (PSD) rates after first-ever and recurrent stroke are ~10 and 30...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Conveniently-Grasped Field Assessment Stroke Triage (CG-FAST): A Modified Scale to Detect Large Vessel Occlusion Stroke
Conclusions: CG-FAST scale could be an effective and simple scale for accurate identification of LVOS among AIS patients. Introduction Large vessel occlusion stroke (LVOS) often leads to severe disability and mortality. Although endovascular therapy (EVT) has been proved to be effective for LVOS patients (1–9), especially in anterior circulation, its benefit is highly time-dependent (10, 11). As hospitals with around-the-clock endovascular capability are scarce in many parts of the world and patients admitted directly to a CSC would have better outcomes than those receiving drip and ship treatment (12, 13), t...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Let's Encourage Congress to Improve Stroke Care FAST
She thought she was choking. It was June of her first year as a member of the Ohio House of Representatives. Joyce Beatty had just returned to her office following a luncheon when she felt her throat shut down. She couldn't swallow, couldn't talk. Couldn't cry for help. As she reached for water, her left side went numb. She collapsed. Someone called 911, thinking it was a heart attack. It was a stroke. Specifically, a brain stem stroke. The brain stem is a precarious spot -- a half-inch wide area that controls basic activities like consciousness, blood pressure and breathing. A stroke there could harm any of those functio...
Source: Healthy Living - The Huffington Post - February 15, 2016 Category: Consumer Health News Source Type: news

Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach
AbstractDue to the reactive medical approach applied to disease management, stroke has reached an epidemic scale worldwide. In 2019, the global stroke prevalence was 101.5 million people, wherefrom 77.2 million (about 76%) suffered from ischemic stroke; 20.7 and 8.4 million suffered from intracerebral and subarachnoid haemorrhage, respectively. Globally in the year 2019 — 3.3, 2.9 and 0.4 million individuals died of ischemic stroke, intracerebral and subarachnoid haemorrhage, respectively. During the last three decades, the absolute number of cases increased substantially. The current prevalence of stroke is 110 million ...
Source: EPMA Journal - November 17, 2022 Category: International Medicine & Public Health Source Type: research

The structured ambulatory post-stroke care program for outpatient aftercare in patients with ischaemic stroke in Germany (SANO): an open-label, cluster-randomised controlled trial
This study was registered with the German Clinical Trials Register, DRKS00015322.FINDINGS: Between Jan 1, 2019 and Dec 22, 2020, 36 clusters were assessed for eligibility, of which 30 were randomly assigned to the intervention group (n=15 clusters) or control group (n=15 clusters). No clusters dropped out of the study. 1203 (86%) of 1396 enrolled patients in the intervention group and 1283 (92%) of 1395 enrolled patients in the control group were included in the mITT population. The primary endpoint was confirmed in 64 (5·3%) of 1203 patients in the intervention group and 80 (6·2%) of 1283 patients in the control group (...
Source: Cancer Control - July 17, 2023 Category: Cancer & Oncology Authors: Christopher J Schwarzbach Felizitas Anna Eichner Viktoria R ücker Anna-Lena Hofmann Moritz Keller Heinrich J Audebert Stephan von Bandemer Stefan T Engelter Dieter Geis Klaus Gr öschel Karl Georg Haeusler Gerhard F Hamann Andreas Meisel Dirk Sander Mart Source Type: research

Association between fasting blood glucose levels and stroke events: a large-scale community-based cohort study from China
Conclusions Higher FBG level was independently associated with an increased risk of stroke in Chinese adults, especially significant in women.
Source: BMJ Open - August 18, 2021 Category: General Medicine Authors: Zhang, Y., Gu, S., Wang, C., Liu, D., Zhang, Q., Yang, M., Zhou, Z., Zuo, H. Tags: Open access, Public health Source Type: research

Investigation of Factors That Affect the Quality of Life After a Stroke
Adv Exp Med Biol. 2023;1425:437-442. doi: 10.1007/978-3-031-31986-0_42.ABSTRACTStroke, as a disease, describes a group of disorders characterized by the presence of central nervous system symptoms either as a result of ischemia (ischemic stroke) or bleeding (hemorrhagic stroke). The appearance of a stroke results in a permanent physical or cognitive disability. The stroke incidence is the third cause of death after heart disease and cancer, and is the main cause of long-term disability.The effects of a stroke on a patient's daily life, and hence on his quality of life, are intense and long-lasting. These include memory pro...
Source: Cancer Control - August 15, 2023 Category: Cancer & Oncology Authors: Maria Malliarou Christina Tsionara Anna Patsopoulou Axilleas Bouletis Vasileios Tzenetidis Iokasti Papathanasiou Evangelia Kotrotsiou Mary Gouva Athanasios Nikolentzos Pavlos Sarafis Source Type: research

Roles of integrins and extracellular matrix in stroke.
Abstract Ischemic stroke is a leading cause of death and disability in the United States, but recent advances in treatments (i.e. endovascular thrombectomy and tissue plasminogen activator (t-PA)) that target the stroke-causing blood clot, while improving overall stroke mortality rates, have had much less of an impact on overall stroke morbidity. This may in part be attributed to the lack of therapeutics targeting reperfusion induced injury after the blood clot has been removed, which, if left unchecked, can expand injury from its core into the surrounding at risk tissue (penumbra). This occurs in two phases of in...
Source: Am J Physiol Cell Ph... - November 21, 2018 Category: Cytology Authors: Edwards D, Bix GJ Tags: Am J Physiol Cell Physiol Source Type: research

Predictors of mortality and disability in stroke-associated pneumonia
AbstractWhilst stroke-associated pneumonia (SAP) is common and associated with poor outcomes, less is known about the determinants of these adverse clinical outcomes in SAP. To identify the factors that influence mortality and morbidity in SAP. Data for patients with SAP (n = 854) were extracted from a regional Hospital Stroke Register in Norfolk, UK (2003–2015). SAP was defined as pneumonia occurring within 7 days of admission by the treating clinicians. Mutlivariable regression models were constructed to assess factors influencing survival and the level of di sability at discharge using modified Rankin Scale [mRS]...
Source: Acta Neurologica Belgica - April 28, 2019 Category: Neurology Source Type: research