Filtered By:
Cancer: Cancer
Education: Academies

This page shows you your search results in order of date. This is page number 2.

Order by Relevance | Date

Total 57 results found since Jan 2013.

Targeted Cancer Therapies.
Abstract Targeted cancer therapies involve chemotherapeutic agents that attack, directly or indirectly, a specific genetic biomarker found in a given cancer. Targeted oncology includes monoclonal antibodies, small molecule inhibitors, antibody-drug conjugates, and immunotherapy. For example, the monoclonal antibodies trastuzumab and pertuzumab target human epidermal growth factor receptor 2 (HER2) and are used when treating HER2-positive breast cancer. Although targeted oncology has improved survival by years for some incurable cancers such as metastatic breast and lung cancer, as few as 8% of patients with advanc...
Source: American Family Physician - January 30, 2021 Category: Primary Care Authors: Smith CEP, Prasad V Tags: Am Fam Physician Source Type: research

Voltage-dependent structural models of the human Hv1 proton channel from long-timescale molecular dynamics simulations Biophysics and Computational Biology
The voltage-gated Hv1 proton channel is a ubiquitous membrane protein that has roles in a variety of cellular processes, including proton extrusion, pH regulation, production of reactive oxygen species, proliferation of cancer cells, and increased brain damage during ischemic stroke. A crystal structure of an Hv1 construct in a putative...
Source: Proceedings of the National Academy of Sciences - June 15, 2020 Category: Science Authors: Andrew D. Geragotelis, Mona L. Wood, Hendrik Goddeke, Liang Hong, Parker D. Webster, Eric K. Wong, J. Alfredo Freites, Francesco Tombola, Douglas J. Tobias Tags: Biological Sciences Source Type: research

In memoriam: Haines Ely, MD, FAAD
Aside from the news about the canceling of the American Academy of Dermatology Annual Meeting in Denver, there is horrible news that is difficult with every key stroke as I write today …Dr Haines Ely, long-standing pinnacle member of Noah Worcester, Pacific Dermatologic Association, RxDerm, and the American Academy of Dermatology, has passed away after a long battle with prostate cancer. He is survived by his wife, Jenny, and adult daughters, Meredith Bordoni (Michael), Rebecca Ely, and Tess Ely.
Source: Journal of the American Academy of Dermatology - March 12, 2020 Category: Dermatology Authors: Neal Bhatia Tags: In memoriam Source Type: research

Cells to Society: Year of the Nurse / Global Impact
This study establishes baseline sociodemographic and clinical characteristics of hospitalized patients in Nepal who were experiencing heart failure.     Read more   Maternal Health ...
Source: Johns Hopkins University and Health Systems Archive - February 6, 2020 Category: Nursing Source Type: news

Study: Drinking Tea May Help You Live Longer, Especially If It ’ s Green
This study strengthens the body of evidence that habitual tea drinking is associated with lower rates of atherosclerotic cardiovascular disease, though it cannot prove that it’s definitely the tea that’s responsible,” Dr. Jenna Macciochi, a lecturer in immunology at the University of Sussex, told the SMC. However, she noted that “a body of evidence in nutrition suggests that whole diet patterns are more informative of diet-disease relationships than any isolated food or nutrient.” Dr. Duane Mellor, a registered dietitian and senior teaching fellow at Aston Medical School, Aston University, sai...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 10, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN Green Tea Source Type: news

Want To Live Longer? Study Suggests You Should Ditch Soda
This study, as well as other research on the connection between diet and sugary beverages and health risks, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage, obesity or another hidden health issue. “The cause behind these associations isn’t clear,” said Bergquist. “Other potential biological causes could be attributed to experimental evidence linking consumption of artificial sweeteners to sugar cravings, appetite stimulation ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 3, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Soda Source Type: news

Sex Difference of Radiation Response in Occupational and Accidental Exposure
Conclusion and Outlook This review summarizes the data from major human studies on the health risks of radiation exposure and shows that sex can potentially influence the prolonged response to radiation exposure (Figure 1 and Tables 1, 2). These data suggest that long-term radiosensitivity in females is higher than that in males who receive a comparable dose of radiation. Our analysis of the literature agrees with the conclusions of the recent report on the Biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences (NAS), United States (National Research Council, 2006). The B...
Source: Frontiers in Genetics - May 2, 2019 Category: Genetics & Stem Cells Source Type: research

Ability to Suppress TGF- β-Activated Myofibroblast Differentiation Distinguishes the Anti-pulmonary Fibrosis Efficacy of Two Danshen-Containing Chinese Herbal Medicine Prescriptions
Conclusion: This study suggests that a clinically efficacious cardiovascular Chinese herbal medicine (DLP) can be successfully repurposed to treat a lung disease in pulmonary fibrosis guided by TCM theory. Our comparative study between DLP and DHP demonstrated a critical requirement of suppressing both pro-inflammatory and pro-fibrotic pathways for the treatment of pulmonary fibrosis, supporting that a multi-component prescription capable of “removing both phlegm and blood stasis” will better achieve co-protection of heart and lung in PHD. Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic ...
Source: Frontiers in Pharmacology - April 23, 2019 Category: Drugs & Pharmacology Source Type: research

Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke
Conclusion In summary, SSS extraction significantly ameliorates cerebral energy metabolism via boosting citrate cycle, which mainly embodies the enhancements of blood glucose concentration, glucose and lactate transportation and glucose utilization, as well as the regulations of relative enzymes activities in citrate cycle. These ameliorations ultimately resulted in numerous ATP yield after stroke, which improved neurological function and infarcted volume. Collectively, it suggests that SSS extraction has exerted advantageous effect in the treatment of cerebral ischemia. Ethics Statement All animal operations were accor...
Source: Frontiers in Pharmacology - April 22, 2019 Category: Drugs & Pharmacology Source Type: research

Cryptotanshinone Attenuates Oxygen-Glucose Deprivation/ Recovery-Induced Injury in an in vitro Model of Neurovascular Unit
Conclusions Despite the above limitations, we indicate that the protective mechanism of CTs against OGD/R damage might exert via inhibiting neuron apoptosis and attenuating BBB disruption. Furthermore, we also clarified that CTs inhibited neuronal apoptosis possibly by blocking the activation of MAPK signaling pathways, and CTs alleviating BBB disruption may associated with the regulation of TJPs and MMP-9 in our experiment. Accordingly, CTs will represent a novel and potent candidate for the treatment of CIRI in the future. Ethics Statement This study was carried out in accordance with the recommendations of China�...
Source: Frontiers in Neurology - April 17, 2019 Category: Neurology Source Type: research

A Nested Case–Control Study on Plasma Vitamin E and Risk of Cancer: Evidence of Effect Modification by Selenium
ConclusionsThis study suggests that higher levels of plasma vitamin E are associated with reduced risk of gastrointestinal cancer. High vitamin E decreased the risk of total cancer among patients with high selenium levels, but increased the risk of total cancer among those with low selenium levels.
Source: Journal of the Academy of Nutrition and Dietetics - February 1, 2019 Category: Nutrition Source Type: research

The Associations of Fruit and Vegetable Intakes with Burden of Diseases: A Systematic Review of Meta-Analyses
ConclusionsThis systematic review supports existing recommendations for fruit and vegetable intakes. Current comparative risk assessments might significantly underestimate the protective associations of fruit and vegetable intakes.
Source: Journal of the Academy of Nutrition and Dietetics - January 12, 2019 Category: Nutrition Source Type: research

3.49 Identification of and Response to Suicide in a Fellow Outpatient Clinic
Suicide is the second leading cause of death for individuals ages 10 to 24 years. More teenagers and young adults die from suicide than from cancer, heart disease, AIDS, birth defects, stroke, pneumonia, influenza, and chronic lung disease, combined. Each day in our nation, there is an average of more than 3470 suicide attempts by young adults attending high school. The main objectives of our literature review are to highlight the importance of recognizing postdischarge period in patients at risk of suicide, critically analyzing the risk and protective factors to formulate an individualized safety plan during transition, a...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - October 1, 2018 Category: Psychiatry Authors: Muhammad Zeshan, Paul G. Hammerness, Muhammad H. Majeed Source Type: research

Cerebral infarction and cortical subarachnoid hemorrhage preceded vascular contraction in reversible cerebral vasoconstriction syndrome patient with hidden breast cancer
We report a case of RCVS with hidden breast cancer in which ischemic stroke and cortical subarachnoid hemorrhage were observed earlier than vasoconstriction, and there were positive autoantibodies.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Changhyo Yoon Seunguk Jung Source Type: research

New funding to UC Riverside to significantly boost cancer, ALS research
(University of California - Riverside) Maurizio Pellecchia at the University of California, Riverside has received two grants to continue his research aimed at finding therapeutics for cancer, amyotrophic lateral sclerosis (ALS), and other neurodegenerative diseases. The first grant from the US-Egypt Science and Technology Joint Fund of the National Academy of Sciences, Engineering, and Medicine totals $190,000 for two years. The second is a nearly $2.3 million, five-year grant from the National Institute of Neurological Disorders and Stroke.
Source: EurekAlert! - Cancer - June 21, 2018 Category: Cancer & Oncology Source Type: news