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Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke
Conclusion In summary, SSS extraction significantly ameliorates cerebral energy metabolism via boosting citrate cycle, which mainly embodies the enhancements of blood glucose concentration, glucose and lactate transportation and glucose utilization, as well as the regulations of relative enzymes activities in citrate cycle. These ameliorations ultimately resulted in numerous ATP yield after stroke, which improved neurological function and infarcted volume. Collectively, it suggests that SSS extraction has exerted advantageous effect in the treatment of cerebral ischemia. Ethics Statement All animal operations were accor...
Source: Frontiers in Pharmacology - April 22, 2019 Category: Drugs & Pharmacology Source Type: research

Study Protocol: IMPETUS: Implementing a uniform stroke care pathway in medical colleges of India: IMPETUS Stroke
We present here a protocol to investigate the feasibility and fidelity of implementing a uniform stroke care pathway in medical colleges of India. Methods and Analysis: This is a multicentric, prospective, multiphase, mixed-method, quasi-experimental implementation study intended to examine the changes in a select set of stroke care-related indicators over time within the sites exposed to the same implementation strategy. We shall conduct process evaluation of the implementation process as well as evaluate the effect of the implementation strategy using the interrupted time series design. During implementation phase, educa...
Source: Annals of Indian Academy of Neurology - September 9, 2022 Category: Neurology Authors: Rohit Bhatia Partha Haldar Inder Puri MV Padma Srivastava Sanjeev Bhoi Menka Jha Anupam Dey Suprava Naik Satyabrata Guru Mamta Bhushan Singh VY Vishnu Roopa Rajan Anu Gupta Deepti Vibha Awadh Kishore Pandit Ayush Agarwal Manish Salunkhe Gunjan Singh Deeps Source Type: research

Clinical and Neuroimaging Features of Acute Ischemic Stroke in Cancer Patients
Background: The occurrence of acute ischemic stroke in cancer patients is not unusual. In clinical practice, acute ischemic stroke with cancer usually cannot be diagnosed promptly due to lack of specific markers. But for cancer patients, advanced prevention, accurate diagnosis and proper treatment of acute ischemic stroke are very important. The aim of the present study was to investigate the clinical and neuroimaging features of acute ischemic stroke in patients with cancer. Methods: We conducted a retrospective review of all cancer-associated acute ischemic stroke patients (n = 46) admitted to the Affiliated Hospital of ...
Source: European Neurology - June 14, 2016 Category: Neurology Source Type: research

Study links severe sleep apnea to increased risk of stroke, cancer and death
(American Academy of Sleep Medicine) A new study shows that moderate to severe obstructive sleep apnea is independently associated with an increased risk of stroke, cancer and death.
Source: EurekAlert! - Cancer - April 14, 2014 Category: Cancer & Oncology Source Type: news

Cryptotanshinone Attenuates Oxygen-Glucose Deprivation/ Recovery-Induced Injury in an in vitro Model of Neurovascular Unit
Conclusions Despite the above limitations, we indicate that the protective mechanism of CTs against OGD/R damage might exert via inhibiting neuron apoptosis and attenuating BBB disruption. Furthermore, we also clarified that CTs inhibited neuronal apoptosis possibly by blocking the activation of MAPK signaling pathways, and CTs alleviating BBB disruption may associated with the regulation of TJPs and MMP-9 in our experiment. Accordingly, CTs will represent a novel and potent candidate for the treatment of CIRI in the future. Ethics Statement This study was carried out in accordance with the recommendations of China�...
Source: Frontiers in Neurology - April 17, 2019 Category: Neurology Source Type: research

Study: Drinking Tea May Help You Live Longer, Especially If It ’ s Green
This study strengthens the body of evidence that habitual tea drinking is associated with lower rates of atherosclerotic cardiovascular disease, though it cannot prove that it’s definitely the tea that’s responsible,” Dr. Jenna Macciochi, a lecturer in immunology at the University of Sussex, told the SMC. However, she noted that “a body of evidence in nutrition suggests that whole diet patterns are more informative of diet-disease relationships than any isolated food or nutrient.” Dr. Duane Mellor, a registered dietitian and senior teaching fellow at Aston Medical School, Aston University, sai...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 10, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN Green Tea Source Type: news

7 Myths About Cholesterol, Debunked
You may not recall every lab value from your last physical, but you probably remember one: Your cholesterol level. If it’s higher than ideal, you’re not alone. According to the U.S. Centers for Disease Control and Prevention, between 2015 and 2018, almost 12% of U.S. adults ages 20 and up had high total cholesterol, defined as above 240 mg/dL. The type that physicians mostly worry about is LDL (or “bad”) cholesterol, which is one component of that total. Why do doctors care so much about cholesterol? First, “it predicts risk,” says Dr. Jeffrey Berger, a cardiologist and director of the C...
Source: TIME: Health - June 19, 2023 Category: Consumer Health News Authors: Katherine Hobson Tags: Uncategorized freelance healthscienceclimate heart health Source Type: news

White Doctors In Training Believe Some Disturbing Stuff About Black Patients
When it comes to emergency care, you may have a tough time if you're in pain and not a white man.  Previous research has shown that black and Hispanic patients who reported severe pain in the the ER were 22 percent less likely to receive pain medication than white patients who presented with the same complaints. And women suffer similar disparities: A 2008 study found that women wait an average of 16 minutes longer to receive pain relief for acute abdominal pain in the ER than men do. Now a new study is shedding some light on this phenomenon. "We’ve been looking at racial bias and pain perception to tr...
Source: Science - The Huffington Post - April 8, 2016 Category: Science Source Type: news

7 Foot Problems That Can Be Serious
If you want to know the state of your health, try looking down. “There’s no question it’s extremely important that people pay attention to their feet,” says Terry Philbin, D.O., spokesperson for the American Academy of Orthopedic Surgeons (AAOS) and a foot and ankle specialist at the Orthopedic Foot and Ankle Center in Westerville, Ohio. The condition of your feet can give you clues to a host of medical issues, such as diabetes, arthritis, and even heart disease. Read on to find out what to look for and what it may mean. 1. Pain “There’s no pain that should be ignored,” says Jane ...
Source: Healthy Living - The Huffington Post - November 12, 2016 Category: Consumer Health News Source Type: news

Long-Term Exposure to Transportation Noise in Relation to Development of Obesity —a Cohort Study
Conclusion: Our results link transportation noise exposure to development of obesity and suggest that combined exposure from different sources may be particularly harmful. https://doi.org/10.1289/EHP1910 Received: 17 March 2017 Revised: 5 October 2017 Accepted: 9 October 2017 Published: 20 November 2017 Address correspondence to A. Pyko, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden. Telephone: 46(0) 852487561. Email: Andrei.pyko@ki.se Supplemental Material is available online (https://doi.org/10.1289/EHP1910). The authors declare they have no actual or potential competing fina...
Source: EHP Research - November 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Cerebral infarction and cortical subarachnoid hemorrhage preceded vascular contraction in reversible cerebral vasoconstriction syndrome patient with hidden breast cancer
We report a case of RCVS with hidden breast cancer in which ischemic stroke and cortical subarachnoid hemorrhage were observed earlier than vasoconstriction, and there were positive autoantibodies.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Changhyo Yoon Seunguk Jung Source Type: research

Want To Live Longer? Study Suggests You Should Ditch Soda
This study, as well as other research on the connection between diet and sugary beverages and health risks, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage, obesity or another hidden health issue. “The cause behind these associations isn’t clear,” said Bergquist. “Other potential biological causes could be attributed to experimental evidence linking consumption of artificial sweeteners to sugar cravings, appetite stimulation ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 3, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Soda Source Type: news

Cells to Society: Year of the Nurse / Global Impact
This study establishes baseline sociodemographic and clinical characteristics of hospitalized patients in Nepal who were experiencing heart failure.     Read more   Maternal Health ...
Source: Johns Hopkins University and Health Systems Archive - February 6, 2020 Category: Nursing Source Type: news

Age and Life-Sustaining Treatment Preferences in Parkinson Disease
Conclusions Advancing age in PD may correlate with paradoxically more aggressive goals as it relates to life-sustaining treatment preferences including cardiopulmonary resuscitation. This may reflect a response to heightened concern among older adults with PD about the potential for compromised autonomy in the setting of aging.
Source: Neurology Clinical Practice - June 7, 2021 Category: Neurology Authors: Jackowiak, E., Szpara, A., Kotagal, V. Tags: Parkinson's disease/Parkinsonism, Palliative care Research Source Type: research

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