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Total 80 results found since Jan 2013.

Use of Nonsteroidal Anti-Inflammatory Drugs and Risk of Chronic Kidney Disease in Subjects With Hypertension: Nationwide Longitudinal Cohort Study Kidney
Limited studies have examined the effects of nonsteroidal anti-inflammatory drug (NSAID) use on the risk of chronic kidney disease (CKD), especially in subjects with hypertension. Using National Health Insurance claims data in Taiwan, we conducted a propensity score–matched cohort study to investigate the relationship between NSAID use and CKD in subjects with hypertension. A total of 31976 subjects were included in this study: subjects not taking any NSAIDs in 2007 (n=10782); subjects taking NSAIDs for 1 to 89 days in 2007 (n=10605); and subjects taking NSAIDs for ≥90 days in 2007 (n=10589). We performed multivar...
Source: Hypertension - August 12, 2015 Category: Cardiology Authors: Hsu, C.-C., Wang, H., Hsu, Y.-H., Chuang, S.-Y., Huang, Y.-W., Chang, Y.-K., Liu, J.-S., Hsiung, C. A., Tsai, H.-J. Tags: Clinical Studies Kidney Source Type: research

Comparative effectiveness of antiarrhythmic drugs for rhythm control of atrial fibrillation.
CONCLUSION: Compared with dronedarone, amiodarone, class 1C agents, and sotalol are more effective for rhythm control, while dofetilide had similar efficacy. These findings have important implications for clinical practice. PMID: 26233885 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - July 29, 2015 Category: Cardiology Authors: Qin D, Leef G, Alam MB, Rattan R, Munir MB, Patel D, Khattak F, Adelstein E, Jain SK, Saba S Tags: J Cardiol Source Type: research

Subsequent mortality after hyperglycemic crisis episode in the non-elderly: a national population-based cohort study
Abstract Hyperglycemic crisis episodes (HCEs)—diabetic ketoacidosis and the hyperosmolar hyperglycemic state—are the most serious acute metabolic complications of diabetes. We aimed to investigate the subsequent mortality after HCE in the non-elderly diabetic which is still unclear. This retrospective national population-based cohort study reviewed, in Taiwan’s National Health Insurance Research Database, data from 23,079 non-elder patients (≤65 years) with new-onset diabetes between 2000 and 2002: 7693 patients with HCE and 15,386 patients without HCE (1:2). Both groups were compared, and follow-up p...
Source: Endocrine - June 27, 2015 Category: Endocrinology Source Type: research

What is the best approach in a patient with a failed aortic bioprosthetic valve: transcatheter aortic valve replacement or redo aortic valve replacement?
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether transcatheter aortic valve-in-valve replacement (viv-TAVR) or redo aortic valve replacement (rAVR) is the best strategy in a patient with a degenerative bioprosthetic aortic valve. Altogether, 162 papers were found using the reported search, of which 12 represented the best evidence to answer the question. The authors, journal, date, country of publication, patient group, study type, outcomes and results of papers are tabulated. The results of the studies provided interesting results. All the studies ...
Source: Interactive CardioVascular and Thoracic Surgery - May 28, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Tourmousoglou, C., Rao, V., Lalos, S., Dougenis, D. Tags: Lung - cancer, Trachea and bronchi, Congestive Heart Failure, Transplantation - heart, Valve disease, Vascular malformations Adult Cardiac Source Type: research

Long-term Mortality Risk After Hyperglycemic Crisis Episodes in Geriatric Patients With Diabetes: A National Population-Based Cohort Study
CONCLUSIONS Patients with diabetes had a higher mortality risk after HCE during the first 6 years of follow-up. Referral for proper education, better access to medical care, effective communication with a health care provider, and control of comorbidities should be done immediately after HCE.
Source: Diabetes Care - April 23, 2015 Category: Endocrinology Authors: Huang, C.-C.; Weng, S.-F.; Tsai, K.-T.; Chen, P.-J.; Lin, H.-J.; Wang, J.-J.; Su, S.-B.; Chou, W.; Guo, H.-R.; Hsu, C.-C. Tags: Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research

Chronic disease prevalence in women and air pollution - A 30-year longitudinal cohort study.
CONCLUSIONS: This study estimated significant elevated prevalent rate ratios per unit increase in PM2.5 in nine of the ten chronic diseases studied. PMID: 25863281 [PubMed - as supplied by publisher]
Source: Environment International - April 6, 2015 Category: Environmental Health Authors: To T, Zhu J, Villeneuve PJ, Simatovic J, Feldman L, Gao C, Williams D, Chen H, Weichenthal S, Wall C, Miller AB Tags: Environ Int Source Type: research

Long-term Mortality Risk After Hyperglycemic Crisis Episodes in Geriatric Patients With Diabetes: A National Population-Based Cohort Study.
CONCLUSIONS: Patients with diabetes had a higher mortality risk after HCE during the first 6 years of follow-up. Referral for proper education, better access to medical care, effective communication with a health care provider, and control of comorbidities should be done immediately after HCE. PMID: 25665811 [PubMed - as supplied by publisher]
Source: Diabetes Care - February 9, 2015 Category: Endocrinology Authors: Huang CC, Weng SF, Tsai KT, Chen PJ, Lin HJ, Wang JJ, Su SB, Chou W, Guo HR, Hsu CC Tags: Diabetes Care Source Type: research

Homocysteine-lowering interventions for preventing cardiovascular events.
CONCLUSIONS: This second update of this Cochrane Review found no evidence to suggest that homocysteine-lowering interventions in the form of supplements of vitamins B6, B9 or B12 given alone or in combination should be used for preventing cardiovascular events. Furthermore, there is no evidence to suggest that homocysteine-lowering interventions are associated with an increased risk of cancer. PMID: 25590290 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - January 15, 2015 Category: Journals (General) Authors: Martí-Carvajal AJ, Solà I, Lathyris D Tags: Cochrane Database Syst Rev Source Type: research

Health care costs for prostate cancer patients receiving androgen deprivation therapy: treatment and adverse events.
CONCLUSIONS: The economic burden of adverse events is relevant to programs and policies from clinic to government, and that burden merits consideration in the risks and benefits of adt. PMID: 24940106 [PubMed]
Source: Current Oncology - November 19, 2014 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate.
Conclusion. ADT in Chinese patients with nonmetastatic prostate cancer with no previously documented cardiovascular disease was associated with subsequent development of cardiovascular events. PMID: 24803931 [PubMed]
Source: Journal of Oncology - November 17, 2014 Category: Cancer & Oncology Tags: J Oncol Source Type: research

The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure
Since the modern era of cancer chemotherapy that began in the mid-1940s, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80% (60). Unfortunately, many long-term survivors of pediatric cancer develop chemotherapy-related health effects; 25% are afflicted with a severe or life-threatening medical condition, with cardiovascular disease being a primary risk (96). Childhood cancer survivors have markedly elevated incidences of stroke, congestive heart failure (CHF), coronary artery disease, and valvular disease (96). Their cardiac mortality is 8.2 times higher tha...
Source: AJP: Heart and Circulatory Physiology - November 15, 2014 Category: Cardiology Authors: Lindsey, M. L., Lange, R. A., Parsons, H., Andrews, T., Aune, G. J. Tags: REVIEW Source Type: research

Fasting Levels of High-Sensitivity Growth Hormone Predict Cardiovascular Morbidity and Mortality The Malmö Diet and Cancer Study
BackgroundBoth pathological excess and deficiency of growth hormone (GH) are associated with cardiovascular mortality.ObjectivesThe goal of this study was to test whether fasting levels of growth hormone measured with a high-sensitivity assay (hs-GH) predict cardiovascular morbidity and mortality at the population level.MethodsWe studied 4,323 participants (age 46 to 68 years; mean age 58 years; 59% women) of the Swedish, population-based Malmö Diet and Cancer study examined in 1991 to 1994. Using multivariate-adjusted Cox proportional hazards models, we related baseline levels of fasting hs-GH to incidence of coronary ar...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - September 29, 2014 Category: Cardiology Source Type: research

The Tell-Tale Heart: Molecular and Cellular Responses to Childhood Anthracycline Exposure.
Abstract Since the modern era of cancer chemotherapy that began in the mid 1940's, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80%. Unfortunately, many long-term survivors of pediatric cancer develop chemotherapy-related health effects; 25% are afflicted with a severe or life-threatening medical condition, with cardiovascular disease being a primary risk. Childhood cancer survivors have markedly elevated incidences of stroke, congestive heart failure (CHF), coronary artery disease (CAD), and valvular disease. Their cardiac mortality is 8.2 times ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 12, 2014 Category: Physiology Authors: Lindsey ML, Lange RA, Parsons H, Andrews T, Aune GJ Tags: Am J Physiol Heart Circ Physiol Source Type: research

Smoking and Atherosclerosis: Mechanisms of Disease and New Therapeutic Approaches.
Abstract It has been clear that at least 1 billion adults worldwide are smokers and at least 700 million children are passive smokers at home. Smoking exerts a detrimental effect to many organ systems and is responsible for illnesses such as lung cancer, pneumonia, chronic obstructive pulmonary disease, cancer of head and neck, cancer of the urinary and gastrointestinal tract, periodontal disease, cataract and arthritis. Additionally, smoking is an important modifiable risk factor for the development of cardiovascular disease such as coronary artery disease, stable angina, acute coronary syndromes, sudden death, s...
Source: Current Medicinal Chemistry - August 26, 2014 Category: Chemistry Authors: Siasos G, Tousoulis D, Michalea S, Oikonomou E, Vavuranakis M, Athanasiou D, Tourikis P, Gouliopoulos N, Miliou A, Mazaris S, Papavassiliou AG, Stefanadis C Tags: Curr Med Chem Source Type: research

Effects of Habitual Coffee Consumption on Cardiometabolic Disease, Cardiovascular Health, and All-cause Mortality: O'Keefe JH, Bhatti SK, Patil HR. J Am Coll Cardiol 2013;62:1043−51.
This study examines existing data regarding coffee consumption and its effect on health and all-cause mortality. Coffee consumption confers a benefit in the reduction of Type II diabetes mellitus (T2DM). There was significant reduction in a dose-dependent relationship of coffee consumption and reduction of T2DM. Caffeinated and noncaffeinated beverages confer the same benefit. The authors conclude that coffee's effect on serum lipids is a dose-dependent increase in serum total cholesterol and a nonsignificant increase in low-density lipoprotein concentrations in only boiled preparations of coffee, but not for filtered coff...
Source: The Journal of Emergency Medicine - April 24, 2014 Category: Emergency Medicine Authors: Java Tunson Tags: Abstracts Source Type: research