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Total 22096 results found since Jan 2013.
Impact of glazing on wear, fracture load, and optical properties of a new fully crystallized lithium disilicate ceramic material
CONCLUSIONS: The glazed fully crystallized LDS was superior to the partially crystallized one with regard to wear resistance but showed more color changes than the polished fully crystallized one. Furthermore, polishing of fully crystallized LDS could still be considered a better option than glazing when aesthetics is a primary prerequisite.PMID:37660448 | DOI:10.1016/j.jmbbm.2023.106102
Source: Journal of the Mechanical Behavior of Biomedical Materials - September 3, 2023 Category: Materials Science Authors: Ahmed Mahmoud Fouda Bogna Stawarczyk Mutlu Özcan Lamia Singer Christoph Bourauel Source Type: research
Safety and efficacy of the epithelial sodium channel blocker idrevloride in people with primary ciliary dyskinesia (CLEAN-PCD): a multinational, phase 2, randomised, double-blind, placebo-controlled crossover trial
Lancet Respir Med. 2023 Aug 31:S2213-2600(23)00226-6. doi: 10.1016/S2213-2600(23)00226-6. Online ahead of print.ABSTRACTBACKGROUND: Mucociliary clearance is dysfunctional in people with primary ciliary dyskinesia, resulting in the accumulation of dehydrated mucus in the airways that is difficult to clear. We undertook a study to assess the benefit on lung function of treatment with a nebulised epithelial sodium channel (ENaC) blocker, idrevloride, with or without hypertonic saline, in people with primary ciliary dyskinesia.METHODS: The CLEAN-PCD trial was a phase 2, randomised, double-blind, placebo-controlled crossover tr...
Source: Respiratory Care - September 3, 2023 Category: Respiratory Medicine Authors: Felix C Ringshausen Adam J Shapiro Kim G Nielsen Henryk Mazurek Massimo Pifferi Karl H Donn Menno M van der Eerden Michael R Loebinger Maimoona A Zariwala Margaret W Leigh Michael R Knowles Thomas W Ferkol CLEAN-PCD investigators and study team Source Type: research
Associations between anthropometric parameters and immune-phenotypical characteristics of circulating Tregs and serum cytokines
CONCLUSIONS: Anthropometric measures are associated with Tregs and serum cytokine concentrations revealing new important interconnections between obesity and the adaptive immune system.PMID:37659013 | DOI:10.1007/s00011-023-01777-1
Source: Cell Research - September 2, 2023 Category: Cytology Authors: Timo Schmitz D Freuer C Meisinger J Linseisen Source Type: research
Global Brassicaceae phylogeny based on filtering of 1,000-gene dataset
Curr Biol. 2023 Aug 28:S0960-9822(23)01069-2. doi: 10.1016/j.cub.2023.08.026. Online ahead of print.ABSTRACTThe mustard family (Brassicaceae) is a scientifically and economically important family, containing the model plant Arabidopsis thaliana and numerous crop species that feed billions worldwide. Despite its relevance, most phylogenetic trees of the family are incompletely sampled and often contain poorly supported branches. Here, we present the most complete Brassicaceae genus-level family phylogenies to date (Brassicaceae Tree of Life or BrassiToL) based on nuclear (1,081 genes, 319 of the 349 genera; 57 of the 58 tri...
Source: Current Biology - September 2, 2023 Category: Biology Authors: Kasper P Hendriks Christiane Kiefer Ihsan A Al-Shehbaz C Donovan Bailey Alex Hooft van Huysduynen Lachezar A Nikolov Lars Nauheimer Alexandre R Zuntini Dmitry A German Andreas Franzke Marcus A Koch Martin A Lysak Óscar Toro-Núñez Bar ış Özüdoğru V Source Type: research
Sensors, Vol. 23, Pages 7623: Utilizing Motion Capture Systems for Instrumenting the OCRA Index: A Study on Risk Classification for Upper Limb Work-Related Activities
a-Bastidas
In the search to enhance ergonomic risk assessments for upper limb work-related activities, this study introduced and validated the efficiency of an inertial motion capture system, paired with a specialized platform that digitalized the OCRA index. Conducted in a semi-controlled environment, the proposed methodology was compared to traditional risk classification techniques using both inertial and optical motion capture systems. The inertial method encompassed 18 units in a Bluetooth Low Energy tree topology network for activity recording, subsequently analyzed for risk using the platform. Principal outcomes...
Source: Sensors - September 2, 2023 Category: Biotechnology Authors: Pablo Aqueveque Guisella Pe ña Manuel Guti érrez Britam G ómez Enrique Germany Gustavo Retamal Paulina Ortega-Bastidas Tags: Article Source Type: research
Rapid point-of-care detection of SARS-CoV-2 infection in exhaled breath using ion mobility spectrometry: a pilot study
ConclusionsDespite identifying several peaks by MCC-IMS with significant differences in peak intensity between PCR-negative and PCR-positive samples, finding a classification system that allows reliable differentiation between the two groups proved to be difficult. However, with some modifications to the setup, breath gas analysis using MCC-IMS may be a useful diagnostic toolbox for SARS-CoV-2 infection.Trial registration: This study was registered at ClinicalTrials.gov on September 21, 2020 (NCT04556318; Study-ID: HC-N-H-2004).
Source: European Journal of Medical Research - September 2, 2023 Category: Research Source Type: research
Oncological outcomes of standard versus prolonged time to surgery after neoadjuvant chemoradiotherapy for oesophageal cancer in the multicentre randomised controlled NeoRes II trial
CONCLUSION: Prolonged time to surgery did not improve histological complete response or other pathological endpoints, while there was a strong trend towards worse survival, suggesting caution in routinely delaying surgery for more than six weeks after nCRT.PMID:37657554 | DOI:10.1016/j.annonc.2023.08.010
Source: Ann Oncol - September 1, 2023 Category: Cancer & Oncology Authors: K Nilsson F Klevebro B Sunde I Rouvelas M Lindblad E Szabo I Halldestam U Smedh B Wallner J Johansson G Johnsen E K Aahlin H-O Johannessen G Alexandersson von D öbeln G O Hjortland N Wang Y Shang D Borg A Quaas I Bartella C Bruns W Schr öder M Nilsson Source Type: research
Electronic Patient-Reported Outcome Monitoring to Improve Quality of Life After Joint Replacement: Secondary Analysis of a Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, the PROM-based monitoring intervention led to a small improvement in HRQOL and fatigue among patients with hip or knee replacement, as well as in depression among patients with hip replacement.TRIAL REGISTRATION: Deutsches Register Klinischer Studien ID: DRKS00019916.PMID:37656459 | DOI:10.1001/jamanetworkopen.2023.31301
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Viktoria Steinbeck Benedikt Langenberger Lukas Sch öner Laura Wittich Wolfgang Klauser Martin Mayer David Kuklinski Justus Vogel Alexander Geissler Christoph Pross Reinhard Busse Source Type: research
Effects of combined exercises on shoulder mobility and strength of the upper extremities in breast cancer rehabilitation: a 3-week randomized controlled trial
CONCLUSION: A combined device-supported strength and mobility training (FIVE®) showed no advantages. Therefore, a variety of exercise methods is possible in exercise therapy of breast cancer patients.CLINICAL TRIAL REGISTRATION NUMBER: Since the University of Education Weingarten does not assign clinical trial registration numbers or ethical approval numbers, none could be assigned for this study.PMID:37656241 | DOI:10.1007/s00520-023-07959-1
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Dominique Michels Stefan K önig Alexandra Heckel Source Type: research
Electronic Patient-Reported Outcome Monitoring to Improve Quality of Life After Joint Replacement: Secondary Analysis of a Randomized Clinical Trial
CONCLUSIONS AND RELEVANCE: In this randomized clinical trial, the PROM-based monitoring intervention led to a small improvement in HRQOL and fatigue among patients with hip or knee replacement, as well as in depression among patients with hip replacement.TRIAL REGISTRATION: Deutsches Register Klinischer Studien ID: DRKS00019916.PMID:37656459 | DOI:10.1001/jamanetworkopen.2023.31301
Source: Cancer Control - September 1, 2023 Category: Cancer & Oncology Authors: Viktoria Steinbeck Benedikt Langenberger Lukas Sch öner Laura Wittich Wolfgang Klauser Martin Mayer David Kuklinski Justus Vogel Alexander Geissler Christoph Pross Reinhard Busse Source Type: research
Therapeutic antibodies in rheumatology
Z Rheumatol. 2023 Sep 1. doi: 10.1007/s00393-023-01409-3. Online ahead of print.ABSTRACTEmil von Behring's serum therapy for diphtheria was the first therapeutic use of antibodies. More than 100 years later, a new era in the treatment of rheumatic diseases began in 1998 with the approval of infliximab, an antibody directed against tumor necrosis factor alpha (TNF alpha). The special feature of antibody therapy is the ability to bind and neutralize antigens in a highly specific manner. In addition, target cells can be eliminated by activation of the immune system. These properties of the immune system are exploited in rheum...
Source: Zeitschrift fur Rheumatologie - September 1, 2023 Category: Rheumatology Authors: Fredrik N Albach Gerd-R üdiger Burmester Johanna Mucke Source Type: research
The Development of Predictive Gender Processing Strategies During Noun Phrase Decoding: An Eye-Tracking Study With German 5- to 10-Year-Old Children
CONCLUSION: Predictive processing of gender cues plays a role in German language comprehension even in children younger than 8 years.PMID:37656484 | DOI:10.1044/2023_JSLHR-23-00100
Source: Journal of speech, language, and hearing research : JSLHR - September 1, 2023 Category: Speech-Language Pathology Authors: Thomas G ünther Annika Kirschenkern Axel Mayer Frederike Steinke J ürgen Cholewa Source Type: research
