Filtered By:
Specialty: Genetics & Stem Cells
This page shows you your search results in order of date. This is page number 5.
Order by Relevance | Date
Total 1523 results found since Jan 2013.
GSE222598 Effect of SF3B4 depletion on gene expression of A549 lung cancer cell
Contributor : Tao LiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the function SF3B4 during the progression of lung cancer, A549 cells with either SF3B4 siRNA or scramble siRNA were used for RNA-seq.
Source: GEO: Gene Expression Omnibus - May 31, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
GSE175671 U2AF1 plays a critical role in global co-transcriptional splicing (Fraction chrRNA-seq)
Contributors : Yajing Hao ; Changwei Shao ; Xiang-Dong FuSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensIn order to measure the impact of U2AF1 on co-transcriptional splicing, we treated HeLa cells with control siRNA or U2AF1 siRNA. To measure co-transcriptional splicing, we fractionated HeLa cells into cytosolic (Cyt), nucleoplasm (NP), and chromatin/particle (Chr) fractions. We purified total RNA from Chr compartment, spiked in with in vitro transcribed EGFP and FireFly luciferase RNA for data normalization, depleted ribosomal RNAs, and constructed two independent libraries for RNA-seq.
Source: GEO: Gene Expression Omnibus - May 27, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Genes, Vol. 14, Pages 1157: High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer
In this study, data from the Cancer Genome Atlas (TCGA), Clinical Proteomic Tumor Analysis Consortium (CPTAC), Human Protein Atlas (HPA), and Genotype-Tissue Expression (GTEx) databases were used to analyze the expression of GMFG in pan-cancer and the correlation between clinical factors. Gene Set Cancer Analysis (GSCA) and Gene Set Enrichment Analysis (GSEA) were also used to analyze the functional differences between the different expression levels and predict the downstream pathways. GMFG expression in breast cancer tissues, and its related biological functions, were further analyzed by immunohistochemistry (IHC), immun...
Source: Genes - May 26, 2023 Category: Genetics & Stem Cells Authors: Yonglin Zhao Xing Wei Jia Li Yan Diao Changyou Shan Weimiao Li Shuqun Zhang Fei Wu Tags: Article Source Type: research
GSE209768 Gene expression in AML12 cells after Uhrf2 knock-down
Contributors : Coenraad F Slabber ; Andrii Kuklin ; Sabine WernerSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusWe identified the ubiquitin ligase Uhrf2 as a key regulator of liver regeneration. To determine the underlying mechanisms of action, we performed siRNA-mediated knockdown of Uhrf2 in AML12 cells and analysed the transcriptome of the Uhrf2-deficient cells.
Source: GEO: Gene Expression Omnibus - May 25, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Exosomes-delivered PD-L1 siRNA and CTLA-4 siRNA protect against growth and tumor immune escape in colorectal cancer
CONCLUSION: Exosomes containing PD-L1 siRNA and CTLA-4 siRNA suppressed CRC progression and enhanced tumor immune responses.PMID:37217085 | DOI:10.1016/j.ygeno.2023.110646
Source: Genomics - May 22, 2023 Category: Genetics & Stem Cells Authors: Jian Li Yuxiang Chen Mingmei Liao Shuyi Yu Binwen Yuan Zeming Jia Lin Zhou Yaping Tang Source Type: research
GSE232483 Effect of SRCAP on gene expression during PRRSV infection of Marc-145 cells.
Contributors : Yihong Xiao ; Guofei DingSeries Type : Expression profiling by high throughput sequencingOrganism : Chlorocebus sabaeusTo investigate the SRCAP regulation of gene transcription during PRRSV infection, we established Marc-145 cell lines in which SRCAP gene has been knocked down by siRNA.We then performed gene expression profiling analysis using data obtained from RNA-seq.
Source: GEO: Gene Expression Omnibus - May 21, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Chlorocebus sabaeus Source Type: research
GSE231942 MLL methyltransferases regulate H3K4 methylation to ensure CENP-A assembly at human centromeres
Contributors : Kausika K Malik ; Deepshika Pulimamidi ; Shweta TyagiSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the function of KMT2A and KMT2F in the regulation of gene transcriptiom,siRNA based knock-down of KMT2A and KMT2F was performed in U2OS cells.
Source: GEO: Gene Expression Omnibus - May 15, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
GSE150260 FTO regulated genes in Hepatocellular Carcinoma
Contributor : Shen YinghaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the global genes regulated by FTO high-throughput mRNA sequencing (RNA-Seq) was performed to compare the expression profile between HepG2 cells transfected with control siRNA or FTO siRNA.
Source: GEO: Gene Expression Omnibus - May 10, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
GSE231670 Targeted suppression of siRNA biogenesis in Arabidopsis pollen
Series Type : Non-coding RNA profiling by high throughput sequencing ; Expression profiling by high throughput sequencing ; Methylation profiling by high throughput sequencingOrganism : Arabidopsis thalianaThis SuperSeries is composed of the SubSeries listed below.
Source: GEO: Gene Expression Omnibus - May 7, 2023 Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by high throughput sequencing Expression profiling by high throughput sequencing Methylation profiling by high throughput sequencing Arabidopsis thaliana Source Type: research
GSE231669 Targeted suppression of siRNA biogenesis in Arabidopsis pollen RNA-seq
Contributor : Filipe BorgesSeries Type : Expression profiling by high throughput sequencingOrganism : Arabidopsis thalianaWe used the RNaseIII-like protein RTL1 to suppress siRNA biogenesis specifically in Arabidopsis pollen, and found distinct siRNA subsets produced in the sperm and vegetative cell lineages via the RNA polymerase IV (Pol IV).
Source: GEO: Gene Expression Omnibus - May 7, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Arabidopsis thaliana Source Type: research
GSE231668 Targeted suppression of siRNA biogenesis in Arabidopsis pollen small RNA-seq
Contributor : Filipe BorgesSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Arabidopsis thalianaWe used the RNaseIII-like protein RTL1 to suppress siRNA biogenesis specifically in Arabidopsis pollen, and found distinct siRNA subsets produced in the sperm and vegetative cell lineages via the RNA polymerase IV (Pol IV).
Source: GEO: Gene Expression Omnibus - May 7, 2023 Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by high throughput sequencing Arabidopsis thaliana Source Type: research
GSE231667 Targeted suppression of siRNA biogenesis in Arabidopsis pollen bisulfite-seq
Contributor : Filipe BorgesSeries Type : Methylation profiling by high throughput sequencingOrganism : Arabidopsis thalianaWe used the RNaseIII-like protein RTL1 to suppress siRNA biogenesis specifically in Arabidopsis pollen, and found distinct siRNA subsets produced in the sperm and vegetative cell lineages via the RNA polymerase IV (Pol IV).
Source: GEO: Gene Expression Omnibus - May 7, 2023 Category: Genetics & Stem Cells Tags: Methylation profiling by high throughput sequencing Arabidopsis thaliana Source Type: research
GSE227774 Differential gene expression profile analysis of parental, Cas9-p15 control, and MELK knockout cells
Contributor : Chandra BartholomeuszSeries Type : Expression profiling by arrayOrganism : Homo sapiensTriple-negative breast cancer (TNBC) has high relapse and metastasis rates and a high proportion of cancer stem-like cells (CSCs), which possess self-renewal and tumor initiation capacity. MELK (maternal embryonic leucine zipper kinase), a protein kinase of the Snf1/AMPK kinase family, is known to promote CSC maintenance and malignant transformation. Our study showed that MELK knockdown using siRNA or MELK inhibition using the MELK inhibitor MELK-In-17 significantly reduced invasiveness, reversed epithelial-to-mesenchymal t...
Source: GEO: Gene Expression Omnibus - May 1, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
