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Specialty: Genetics & Stem Cells
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Total 1523 results found since Jan 2013.
Expression patterns and biological function of BCL2L10 during mouse preimplantation development
Gene Expr Patterns. 2022 Oct 29;46:119285. doi: 10.1016/j.gep.2022.119285. Online ahead of print.ABSTRACTBCL2-like 10 (BCL2L10) is abundantly expressed in mammalian oocytes and plays a crucial role in the completion of oocyte meiosis. However, the expression patterns of BCL2L10 and its biological functions during preimplantation development have not been well characterized. Here, we investigated the spatiotemporal expressions of Bcl2l10 during mouse preimplantation development using RT-qPCR and immunofluorescence and its biological function using siRNA and morpholino injection into pronuclear embryos. Results from RT-qPCR ...
Source: Gene Expression Patterns : GEP - November 7, 2022 Category: Genetics & Stem Cells Authors: Yong Liu Jing Xin Shengnan Zhang Qingmei Li Wenying Wang Ji Chen Xin Ming Xiaoqing Wu Xinyan Cao Wei Cui Hongcheng Wang Wenyong Li Source Type: research
GSE216863 Comparison of gene profiles of human bone marrow stromal stem cell (hBMSCs) transfected by siRNA-Control and siRNA-KIAA1199
Contributor : Li ChenSeries Type : Expression profiling by arrayOrganism : Homo sapienshuman bone marrow stromal stem cells were transfected by siRNA-control (non-target) and siRNA-KIAA1199, after 72 hours, gene profiles were comparedWe used microarrays to detail the global programme of gene expression underlying cellularization and identified distinct classes of up-regulated genes during this process.
Source: GEO: Gene Expression Omnibus - October 31, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
GSE185368 RNA-Seq of rat cardiac fibroblasts depleted for Yap and Wwtr1
Contributors : Micahel A Flinn ; Xiaoxu Zhou ; Pengyuan Liu ; Caitlin C O'MearaSeries Type : Expression profiling by high throughput sequencingOrganism : Rattus norvegicusPrimary neonatal rat cardiac fibroblasts were isolated and subjected to siRNA mediated Yap and/or Wwtr1 knockdown
Source: GEO: Gene Expression Omnibus - October 29, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Rattus norvegicus Source Type: research
GSE216519 Effect of depletion of AIM2 on gene expression in psoriatic NETs-treated primary human keratinocytes
Contributors : Xu Yuan ; Tianyu Cao ; Shuai ShaoSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the function of the NET-AIM2 axis on keratinocyte activation during psoriasis, we established psoriatic NETs-treated primary human keratinocytes in which AIM2 has been knocked down by siRNA
Source: GEO: Gene Expression Omnibus - October 28, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
GSE215344 Characterization of a NEK7-related pyroptosis gene signature against pancreatic cancer and evaluation of its potential in tumor microenvironment remodeling via regulating inflammasome complex
Contributors : Jianhua Qu ; Zilong YanSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the biological function of NEK7 in pyroptosis of pancreatic cancer cells, we manipulate the expression of NEK7 and NEK6 in pancreatic cancer cell lines in which each target gene has been knocked down by siRNA.
Source: GEO: Gene Expression Omnibus - October 14, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
GSE206142 Effect of knockdown of DIO3OS and PTBP1 on gene expression of MCF-7 LTED cells cellseq
Contributors : Xueman Chen ; Man-Li Luo ; Erwei SongSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensTo investigate the function of DIO3OS and PTBP1 in the metabolic regulation, we used LNA and siRNA to silence DIO3OS and PTBP1, respectively, in established MCF-7 LTED cell lines. We then performed gene expression profiling analysis using data obtained from RNA-seq of six different cells.
Source: GEO: Gene Expression Omnibus - October 11, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
GSE201426 RNA sequencing of HeLa cells
In this study TOP3A, TOP1MT or both TOP3A and TOP1MT have been knocked down using siRNAs to determine the effect of the topoisomerases on mitochondrial transcription. RNA was isolated from ctrl siRNA, TOP3A siRNA, TOP1MT siRNA and TOP3A + TOP1MT siRNA transfected cells after 6 days of transfection.
Source: GEO: Gene Expression Omnibus - October 11, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
