Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
Ontogeny and tissue specific expression profiles of recombination activating genes (RAGs) during development in Nile tilapia, Oreochromisniloticus
Gene Expr Patterns. 2024 Mar 7;52:119358. doi: 10.1016/j.gep.2024.119358. Online ahead of print.ABSTRACTRecombination activating genes (RAGs) mediates the process of rearrangement and somatic recombination (V(D)J) to generate different antibody repertoire. Studies on the expression pattern of adaptive immune genes during ontogenic development are crucial for the formulation of fish immunization strategy. In the present study, Nile tilapia was taken to explore the relative expression profile of RAG genes during their developmental stages. The developmental stages of Nile tilapia, i.e., unfertilized egg, 0, 2, 4, 6, 8, 10, 1...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Ravikumar M Chovatia Arpit Acharya Kiran D Rasal Megha Kadam Bedekar Kezhedath Jeena R Bharathi Rathinam Chandana Dinakaran Gayatri Tripathi Source Type: research
Transcriptional regulation of the alternative sex hormone-binding globulin promoter by KLF4
Gene Expr Patterns. 2024 Mar 7:119357. doi: 10.1016/j.gep.2024.119357. Online ahead of print.ABSTRACTIn most mammals the major site of sex hormone-binding globulin (SHBG) synthesis is the liver wherefrom it is secreted into the bloodstream and is the primary determinant of sex steroid access to target tissues. The minor site of SHBG synthesis is the testis and in lower mammals testicular SHBG has long been known to be synthesized and secreted by Sertoli cells. However, human testicular SHBG is expressed in developing germ cells from an upstream alternative promoter (altP-SHBG). Transcripts arising from this region comprise...
Source: Gene Expression Patterns : GEP - March 9, 2024 Category: Genetics & Stem Cells Authors: Warren M Meyers Source Type: research
