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Condition: Diabetes
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Total 1499 results found since Jan 2013.
ATF3 Regulates Osteogenic Function by Mediating Osteoblast Ferroptosis in Type 2 Diabetic Osteoporosis
CONCLUSION: Osteoblast ferroptosis under HG conditions is induced by ATF3-mediated inhibition of system Xc- activity, and these events contribute to T2DOP pathogenesis.PMID:36340581 | PMC:PMC9629949 | DOI:10.1155/2022/9872243
Source: Disease Markers - November 7, 2022 Category: Laboratory Medicine Authors: Yantao Zhao Yunxia Du Yijie Gao Zhijie Xu Dexiang Zhao Maowei Yang Source Type: research
Transient receptor potential canonical 6 knockdown ameliorated diabetic kidney disease by inhibiting nuclear factor of activated T cells 2 expression in glomerular mesangial cells
CONCLUSION: These results demonstrate that inhibition of TRPC6/NFAT2 signaling attenuates GMC dysfunction and the development of DKD and suggest that pharmacological targeting of TRPC6/NFAT2 in GMCs may provide beneficial effects for DKD.PMID:36285371 | DOI:10.1080/0886022X.2022.2134796
Source: Renal Failure - October 26, 2022 Category: Urology & Nephrology Authors: Jian Yu Chunchun Li Lisha Ma Bin Zhai Aiping Xu Decui Shao Source Type: research
Swinhoeic acid from < em > Potentilla fragarioides < /em > ameliorates high glucose-induced oxidative stress and accumulation of ECM in mesangial cells via Keap1-dependent activation of Nrf2
CONCLUSION: Swinhoeic acid ameliorates oxidative stress and accumulation of ECM resulting from high glucose in mesangial cells via activating Nrf2 in Keap1-dependent manner.PMID:36259553 | DOI:10.1080/13510002.2022.2134755
Source: Redox Report : communications in free radical research - October 19, 2022 Category: Biochemistry Authors: Huankai Yao Min Kong Dan Du Fengwei Ai Jindong Li Yan Li Source Type: research
