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Condition: Thrombosis

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Total 39135 results found since Jan 2013.

Assessing Abdominal Aortic Aneurysm Progression by Using Perivascular Adipose Tissue Attenuation on Computed Tomography Angiography
CONCLUSION: Elevated PVAT attenuation is independently associated with AAA progression, including patients of AAA with ILT, suggesting the potential of PVAT attenuation as a predictive imaging marker for AAA expansion.PMID:37724591 | DOI:10.3348/kjr.2023.0339
Source: Korean J Radiol - September 19, 2023 Category: Radiology Authors: Shuai Zhang Hui Gu Na Chang Sha Li Tianqi Xu Menghan Liu Ximing Wang Source Type: research

Efficacy of TACE Combined with Lenvatinib Plus Sintilimab for Hepatocellular Carcinoma with Tumor Thrombus in the Inferior Vena Cava and/or Right Atrium
CONCLUSION: TACE combination with lenvatinib plus sintilimab is effective in treating HCC with IVC and/or RA TT. The toxicities were manageable, with no unexpected safety signals. The baseline levels of serum PCT might be the predictive biomarkers for the triple combination therapy.PMID:37724186 | PMC:PMC10505388 | DOI:10.2147/JHC.S410967
Source: Cancer Control - September 19, 2023 Category: Cancer & Oncology Authors: Shangkun Ning Xinge Li Xiangyu Ma Jibing Liu Xu Chang Source Type: research

Assessing Abdominal Aortic Aneurysm Progression by Using Perivascular Adipose Tissue Attenuation on Computed Tomography Angiography
CONCLUSION: Elevated PVAT attenuation is independently associated with AAA progression, including patients of AAA with ILT, suggesting the potential of PVAT attenuation as a predictive imaging marker for AAA expansion.PMID:37724591 | DOI:10.3348/kjr.2023.0339
Source: Atherosclerosis - September 19, 2023 Category: Cardiology Authors: Shuai Zhang Hui Gu Na Chang Sha Li Tianqi Xu Menghan Liu Ximing Wang Source Type: research

Coagulation Factor VIII Regulates von Willebrand Factor Homeostasis In Vivo
CONCLUSION: Our results demonstrate the pivotal role of FVIII as a cofactor regulating VWF proteolysis and homeostasis under various (patho) physiological conditions.PMID:37726033 | DOI:10.1016/j.jtha.2023.09.004
Source: Thrombosis and Haemostasis - September 19, 2023 Category: Hematology Authors: Wenjing Cao Aria R Trask Antonia I Bignotti Lindsey A George Bhavya S Doshi Denise E Sabatino Noritaka Yada Liang Zheng Rodney M Camire X Long Zheng Source Type: research

Predicting in-hospital mortality in patients admitted from the emergency department for pulmonary embolism: Incidence and prognostic value of deep vein thrombosis. A retrospective study
CONCLUSIONS: Although further studies are needed to confirm the prognostic role of DVT at PE, involvement of the iliocaval venous axis should considered to be a sign of a higher risk of IHM and may be a key factor in prognostic stratification.PMID:37726801 | DOI:10.1111/crj.13697
Source: Respiratory Care - September 19, 2023 Category: Respiratory Medicine Authors: Teresa Pagano Irma Sofia Fabbri Marcello Benedetto Luca D'Angelo Giorgio Galizia Andrea Portoraro Matteo Guarino Benedetta Perna Angelina Passaro Daniele Cariani Michele Domenico Spampinato Roberto De Giorgio Source Type: research

Assessing Abdominal Aortic Aneurysm Progression by Using Perivascular Adipose Tissue Attenuation on Computed Tomography Angiography
CONCLUSION: Elevated PVAT attenuation is independently associated with AAA progression, including patients of AAA with ILT, suggesting the potential of PVAT attenuation as a predictive imaging marker for AAA expansion.PMID:37724591 | DOI:10.3348/kjr.2023.0339
Source: Korean J Radiol - September 19, 2023 Category: Radiology Authors: Shuai Zhang Hui Gu Na Chang Sha Li Tianqi Xu Menghan Liu Ximing Wang Source Type: research

In-Hospital Venous Thromboembolism and Pulmonary Embolism After Major Urologic Cancer Surgery
CONCLUSIONS: RC, RN, and PN predisposes to a higher VTE and PE rates than RP. Moreover, among RC and RN patients with either VTE or PE, mortality is substantially higher than among their VTE or PE-free counterparts.PMID:37721691 | DOI:10.1245/s10434-023-14246-0
Source: Ann Oncol - September 18, 2023 Category: Cancer & Oncology Authors: Cristina Cano Garcia Stefano Tappero Mattia Luca Piccinelli Francesco Barletta Reha-Baris Incesu Simone Morra Lukas Scheipner Andrea Baudo Zhe Tian Benedikt Hoeh Francesco Chierigo Gabriele Sorce Fred Saad Shahrokh F Shariat Luca Carmignani Sascha Ahyai N Source Type: research

Melatonin as a therapeutic agent for alleviating endothelial dysfunction in cardiovascular diseases: Emphasis on oxidative stress
Biomed Pharmacother. 2023 Sep 16;167:115475. doi: 10.1016/j.biopha.2023.115475. Online ahead of print.ABSTRACTThe vascular endothelium is vital in maintaining cardiovascular health by regulating vascular permeability and tone, preventing thrombosis, and controlling vascular inflammation. However, when oxidative stress triggers endothelial dysfunction, it can lead to chronic cardiovascular diseases (CVDs). This happens due to oxidative stress-induced mitochondrial dysfunction, inflammatory responses, and reduced levels of nitric oxide. These factors cause damage to endothelial cells, leading to the acceleration of CVD progr...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Xiaolu Zhang Yujia Zheng Ziyu Wang Jiali Gan Bin Yu Bin Lu Xijuan Jiang Source Type: research

Breaking down tumor thrombus: Current strategies for medical management
Thromb Res. 2023 Sep 13;230:144-151. doi: 10.1016/j.thromres.2023.09.004. Online ahead of print.ABSTRACTTumor thrombus, the intravascular extension of tumor into adjacent blood vessels, is frequently encountered in patients with renal cell carcinoma and hepatocellular carcinoma, and often involves the abdominal vasculature including the renal vein, portal vein, and the inferior vena cava. While a bland thrombus is composed of platelets and fibrin, in contrast, a tumor thrombus refers to an organized collection of tumor cells. Though oftentimes detected incidentally on imaging, tumor thrombus may have significant clinical i...
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Harsha Tathireddy Douglas Rice Kylee Martens Sudeep Shivakumar Joseph Shatzel Source Type: research

Correction: Anticoagulant Therapy for Cancer-Associated Thrombosis
Ann Intern Med. 2023 Sep 19. doi: 10.7326/L23-0345. Online ahead of print.NO ABSTRACTPMID:37722116 | DOI:10.7326/L23-0345
Source: Annals of Internal Medicine - September 18, 2023 Category: Internal Medicine Source Type: research

Long-term outcomes of prophylaxis with a recombinant factor VIII Fc or recombinant factor IX Fc in patients with hemophilia previously treated on demand
CONCLUSIONS: Findings add to existing evidence and demonstrate the clinical and HRQoL benefits of switching patients from on-demand treatment to rFVIIIFc/rFIXFc prophylaxis.PMID:37720484 | PMC:PMC10502440 | DOI:10.1016/j.rpth.2023.102163
Source: Thrombosis and Haemostasis - September 18, 2023 Category: Hematology Authors: Mar ía-Teresa Álvarez-Román Amy D Shapiro Margaret V Ragni Helena Palmborg Linda Bystrick á Johan Szamosi Sandra Casiano Herv é Chambost Source Type: research

Caplacizumab use for immune thrombotic thrombocytopenic purpura: the Milan thrombotic thrombocytopenic purpura registry
Res Pract Thromb Haemost. 2023 Aug 26;7(6):102185. doi: 10.1016/j.rpth.2023.102185. eCollection 2023 Aug.ABSTRACT•Data on caplacizumab use for thrombotic thrombocytopenic purpura (TTP) in Italy are missing.•Twenty-six Italian patients were treated with caplacizumab for an acute immune TTP episode.•Caplacizumab was effective in treating acute TTP in the Italian real-world clinical setting.•Two major bleeds leading to drug discontinuation were observed.PMID:37720483 | PMC:PMC10502422 | DOI:10.1016/j.rpth.2023.102185
Source: Thrombosis and Haemostasis - September 18, 2023 Category: Hematology Authors: Pasquale Agosti Pasqualina De Leo Marco Capecchi Barbara Ferrari Ilaria Mancini Salvatore Gattillo Silvia Maria Trisolini Erminia Rinaldi Gian Marco Podda Lucia Prezioso Prassede Salutari Luca Facchini Domenica Caramazza Giulia Tolomelli Andrea Artoni Flo Source Type: research

Health-related quality of life is impaired in bleeding disorders of unknown cause: results from the Vienna Bleeding Biobank
CONCLUSION: The impairments in HrQoL in patients with BDUC emphasize the burden of BDUC on mental and physical well-being, encouraging early recognition and better counseling of patients with BDUC.PMID:37720482 | PMC:PMC10502434 | DOI:10.1016/j.rpth.2023.102176
Source: Thrombosis and Haemostasis - September 18, 2023 Category: Hematology Authors: Dino Mehic Stephan Schwarz Ihor Shulym Cihan Ay Ingrid Pabinger Johanna Gebhart Source Type: research

A 20-year multicentre retrospective review of optic nerve sheath fenestration outcomes
CONCLUSION: Our data demonstrates effectiveness in the use of ONSF in papilloedema with visual failure due to IIH or CVST and when other CSF diversion procedures or medical therapies have failed.PMID:37719666 | PMC:PMC10501074 | DOI:10.1177/17562864231197994
Source: Adv Data - September 18, 2023 Category: Epidemiology Authors: Shaddy El-Masri Matthew Wilson Jonathan Goh Paul Sanfilippo Anthony Fok Thomas Hardy Rahul Chakrabarti Anneke Van Der Walt Source Type: research