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End-Stage Renal Disease: Medical Management
Am Fam Physician. 2021 Nov 1;104(5):493-499.ABSTRACTEnd-stage renal disease (ESRD) is diagnosed when kidney function is no longer adequate for long-term survival without kidney transplantation or dialysis. Primary care clinicians should refer people at risk of ESRD to nephrology to optimize disease management. Kidney transplantation typically yields the best patient outcomes, although most patients are treated with dialysis. The decision to initiate dialysis is best made through shared decision-making. Because most patients with ESRD elect to receive hemodialysis, the preservation of peripheral veins is important for those...
Source: American Family Physician - November 16, 2021 Category: Primary Care Authors: Noah Wouk Source Type: research
Technical quality assurance and quality control for medical laboratories: a review and proposal of a new concept to obtain integrated and validated QA/QC plans
Crit Rev Clin Lab Sci. 2022 Jun 25:1-15. doi: 10.1080/10408363.2022.2088685. Online ahead of print.ABSTRACTTechnical quality assurance (QA) and quality control (QA/QC) are important activities within medical laboratories to ensure the adequate quality of obtained test results. QA/QC tools available at medical laboratories include external QC and internal QC, patient-based real-time quality control (PBRTQC) tools such as moving average quality control (MAQC), limit checks, delta checks, and multivariate checks, and finally, analyzer flagging. Recently, for PBRTQC tools, new optimization and validation methods based on error...
Source: Cancer Control - June 27, 2022 Category: Cancer & Oncology Authors: Huub H van Rossum Source Type: research
Impact of Digoxin Use on Guideline-Directed Medical Therapy in Patients With Heart Failure With Reduced Ejection Fraction
CONCLUSIONS: There was no significant difference between the doses of BB, ACEI, ARB, MRA, or ARNI among HFrEF patients on digoxin compared to those that were not. Randomized control trials with a larger sample are needed to establish our findings of digoxin not significantly affecting the ability to up titrate GDMT in HFrEF patients.PMID:36128010 | PMC:PMC9451555 | DOI:10.14740/jocmr4772
Source: Clin Med Res - September 21, 2022 Category: Research Authors: Ahmad Jabri Laith Alhuneafat Zaid Shahrori Hani Hamade Farhan Nasser Abdallah Rayyan Mohammed Mhanna Ahmad Al Abdouh Faris Haddadin Kathir Balakumaran Source Type: research
HIPEC morbidity and implications for post-surgical treatment. A medical oncologist advice
Bull Cancer. 2023 Feb 21:S0007-4551(23)00052-8. doi: 10.1016/j.bulcan.2023.01.011. Online ahead of print.ABSTRACTThe fear that the medical oncologist may have is that HIPEC integrated into a multidisciplinary care pathway will negatively impact the treatments that will follow. This fear is largely related to the side effects, which are themselves dependent on the medication used. Cisplatin, most frequently used for epithelial ovarian cancers, has essentially renal toxicity, which can be avoided by the use of sodium thiosulfate. Oxaliplatin induces more severe toxicities post surgery than mitomycin C in colorectal cancers. ...
Source: Bulletin du Cancer - February 23, 2023 Category: Cancer & Oncology Authors: Laurence Gladieff Source Type: research
