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Nutrition: Sodium
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Intensity-dependent mass search for improving metabolite database matches in chemical isotope labeling LC-QTOF-MS-based metabolomics
Anal Chim Acta. 2023 Sep 1;1272:341467. doi: 10.1016/j.aca.2023.341467. Epub 2023 Jun 1.ABSTRACTLiquid chromatography mass spectrometry (LC-MS) has been increasingly used for metabolome analysis. One of the critical steps in the LC-MS metabolome analysis workflow is related to metabolite identification. Among the measured parameters, peak mass is commonly used to search against a database for potential metabolite matches. Higher accuracy mass measurement allows the use of a narrower mass tolerance window for mass search. While various types of mass analyzers can routinely measure a peak mass with an error of less than a fe...
Source: Analytica Chimica Acta - June 24, 2023 Category: Chemistry Authors: Yunong Li Hao Li Taibo Luo Guohui Lin Liang Li Source Type: research
Antiepileptic therapy approaches in KCNQ2 related epilepsy: A systematic review.
CONCLUSIONS: Seizures associated with mutations within the voltage gated potassium channel KCNQ2 are well controlled by medical treatment in patients with 'benign' courses and moderately well in patients with the 'EOEE' group. A significant number of patients in the 'benign' group may experience seizure freedom spontaneously. Phenobarbital might be considered in benign courses, while sodium channel blockers seem appropriate for both 'benign' and 'EOEE' patients.
PMID: 30771507 [PubMed - as supplied by publisher]
Source: European Journal of Medical Genetics - February 13, 2019 Category: Genetics & Stem Cells Authors: Kuersten M, Tacke M, Gerstl L, Hoelz H, Stülpnagel CV, Borggraefe I Tags: Eur J Med Genet Source Type: research
Navigating between Scylla and Charybdis: challenges and strategies for implementing guideline ‐directed medical treatment in heart failure with reduced ejection fraction
This article is protected by copyright. All rights reserved.
Source: European Journal of Heart Failure - November 10, 2021 Category: Cardiology Authors: Petar M Seferovi Ć,
Marija Polovina,
Christopher Adlbrecht,
Jan BĚlohlávek,
Ovidiu Chioncel,
Eva Goncalvesová,
Ivan MilinkoviĆ,
Avishay Grupper,
Róbert Halmosi,
Ginta Kamzola,
Konstantinos C Koskinas,
Yuri Lopatin,
Alexander Parkhomenko, Tags: Review Article Source Type: research
Indications for accurate and appropriate use of personal protective equipment for healthcare professionals. A systematic review
CONCLUSION: Combined use of a face shield with a N95 mask proved to be superior to other associations for protecting healthcare workers. Some products are useful for disinfecting PPE, such as 70% ethanol, 0.1% sodium hypochlorite and a mixture of quaternary ammonium and H2O2, and hydrogen peroxide. Ultraviolet light and dry heat at 70 °C can be used to decontaminate N95 masks.REGISTRATION NUMBER: DOI: 10.17605/OSF.IO/4V5FD at the OPENSCIENCE Framework.PMID:34932781 | DOI:10.1590/1516-3180.2021.0128.R1.18052021
Source: Sao Paulo Medical Journal - December 21, 2021 Category: General Medicine Authors: Maria Stella Peccin M árcio Luís Duarte Aline Mizusaki Imoto M ônica Taminato Humberto Saconato Maria Eduarda Puga Eduardo Signorini Bicas Franco Erika Barbosa Camargo Leila Bernarda Donato Gottems Álvaro Nagib Atallah Source Type: research
