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Total 126957 results found since Jan 2013.
Development in the Inhibition of Dengue Proteases as Drug Targets
CONCLUSION: Different classes of compounds have been reported against DENV, such as nitrogen-containing heterocycles (i.e., imidazole, pyridine, triazoles quinazolines, quinoline, and indole), oxygen-containing heterocycles (i.e., coumarins), and some are mixed heterocyclic compounds of S, N (thiazole, benzothiazine, and thiazolidinediones), and N, O (i.e., oxadiazole). There have been reports of computationally designed compounds to impede the molecular functions of specific structural and non-structural proteins as potential therapeutic targets. This review summarized the current progress in developing dengue protease in...
Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Muhammad Akram Shehryar Hameed Abbas Hassan Khalid Khan Source Type: research
Establishment and multicenter external validation of a risk prediction model for de novo intracranial aneurysms based on a systematic review and meta-analysis of 19 cohorts
CONCLUSIONS: This prediction model is a convenient and intuitive tool for identifying high-risk patients with de novo IAs. Reasonable use of the model can not only aid in clinical decision-making but also play a positive role in the prevention of aneurysmal subarachnoid hemorrhage to a certain extent.PMID:37724813 | DOI:10.3171/2023.7.JNS23749
Source: Journal of Neurosurgery - September 19, 2023 Category: Neurosurgery Authors: Jiahe Tan Rui Song Jun Su Hongyu Wu Wenqiao Fu Yinrui Ma Zhaohui He Source Type: research
Moral resilience in registered nurses: Cultural adaption and validation study
This study aimed to translate the Rushton Moral Resilience Scale (RMRS) into Chinese and evaluate the psychometric properties of the Chinese version of RMRS (Chi-RMRS).RESEARCH DESIGN: A methodological and descriptive research design.PARTICIPANTS AND RESEARCH CONTEXT: A convenience sample of 411 Chinese professional nurses was recruited through an online survey platform between February and March 2023.ETHICAL CONSIDERATIONS: This study was approved by the Research Ethics Committees of the University and hospitals involved.RESULTS: The RMRS was translated and culturally adapted into a Chinese version. Neither floor nor ceil...
Source: Nursing Ethics - September 19, 2023 Category: Nursing Authors: Xu Tian Qiaoling He Xiaoling Liu Xiuni Gan Mar ía F Jiménez Herrera Source Type: research
Study of microscopic properties and heavy metal solidification mechanism of electrolytic manganese residue-based cementitious materials
This study aimed to prepare cementitious materials containing abundant ettringite crystals by mixing EMR with various proportions of granulated blast furnace slag (GBFS) and alkaline activators (CaO, Ca(OH)2, clinker, NaOH). The resulting cementitious material not only utilized a substantial amount of EMR but also exhibited comparable strength to ordinary Portland cement. The optimal ratios were determined through mechanical testing. Additionally, the leaching toxicity of cementitious materials was assessed using ICP-MS (inductively coupled plasma mass spectrometer) tests. The microscopic properties, hydration, and mechani...
Source: Environmental Science and Pollution Research International - September 19, 2023 Category: Environmental Health Authors: Liang Tang Zhaoyi He Kefan Chen Xiaoli Wang Yixun Xiao Zhou Yu Haixin Xiao Source Type: research
Associations of polychlorinated biphenyl and organochlorine pesticide exposure with hyperuricemia: modification by lifestyle factors
Environ Sci Pollut Res Int. 2023 Sep 20. doi: 10.1007/s11356-023-29938-z. Online ahead of print.ABSTRACTRecent research has reported positive associations of exposure to polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) with hyperuricemia. However, most of these studies have primarily focused on the individual effects of PCB/OCP exposure. We aimed to explore the associations of both individual and combined PCB/OCP exposure with hyperuricemia and examine whether such associations could be modified by lifestyle factors. The cross-sectional study recruited 2032 adults between March and May 2019 in Wuhan, C...
Source: Environmental Science and Pollution Research International - September 19, 2023 Category: Environmental Health Authors: Gaojie Fan Qing Liu Jianing Bi Qing Fang Xiya Qin Mingyang Wu Yongman Lv Surong Mei Youjie Wang Zhengce Wan Lulu Song Source Type: research
Investigation of industry 4.0 technologies mediating effect on the supply chain performance and supply chain management practices
Environ Sci Pollut Res Int. 2023 Sep 19. doi: 10.1007/s11356-023-29550-1. Online ahead of print.ABSTRACTThe aim of the present article purposefully explores how industry 4.0 may alter conventional methods of administration by performance of supply chain. Nowadays, the business activities/processes have been raised and all are directly associated with industrial revolution. Industry 4.0 acts as a go-between for improved supply chain efficiency and more traditional forms of logistics management. Discovering the transformative effects of industry 4.0 on supply chain management by reading on, however, SCM practices, this study...
Source: Environmental Science and Pollution Research International - September 19, 2023 Category: Environmental Health Authors: Yeming Lv Yuxiao Shang Source Type: research
Low-cost urban carbon monitoring network and implications for china: a comprehensive review
Environ Sci Pollut Res Int. 2023 Sep 19. doi: 10.1007/s11356-023-29836-4. Online ahead of print.ABSTRACTThe development and renewal of gas sensor technology have enabled more and more low-cost gas sensors to form a carbon monitoring network to meet the requirements of the city. In the context of China's commitment to achieving the "double carbon" target by 2060, this paper reviews the principles of four standard gas sensors and the application of several low-cost sensors in urban carbon monitoring networks, with the aim of providing a practical reference for the future deployment of carbon monitoring networks in Chinese ci...
Source: Environmental Science and Pollution Research International - September 19, 2023 Category: Environmental Health Authors: Hongzhi Jiang Yang Han Amr S Zalhaf Ping Yang Congling Wang Source Type: research
A dynamic model of coalbed methane emission from boreholes in front of excavation working face: numerical model and its application
This study provides a new outburst prediction method, which involves identifying outburst hazards through the gas gushing out of the borehole. The results are expected to aid the control of underground coal and gas outbursts and ensure the safe production of coal mines.PMID:37726625 | DOI:10.1007/s11356-023-29793-y
Source: Environmental Science and Pollution Research International - September 19, 2023 Category: Environmental Health Authors: Yunlong Zou Weihao Wang Jinyang Fan Peng Liu Zongze Li Deyi Jiang Source Type: research
Digital technology and its application in supply chain management: new evidence from China's economy
Environ Sci Pollut Res Int. 2023 Sep 19. doi: 10.1007/s11356-023-29486-6. Online ahead of print.ABSTRACTThe purpose of this article is to investigate the influence that practices using information technology (IT) have on the development of a competitive advantage across the supply chain. An organization has a competitive advantage when it has qualities that give the required foundations for it to separate itself from other organizations that are also in its industry. Pressure is applied to the corporate environment as a result of competition and ongoing changes, such as the introduction of new products and technical advanc...
Source: Environmental Science and Pollution Research International - September 19, 2023 Category: Environmental Health Authors: Huang Hua Wang Jinliang Wasim Iqbal Yuk Ming Tang Ka Yin Chau Source Type: research
Association between ADAMTS14_rs4747096 gene polymorphism and bone mineral density of Chinese Han population residing in fluorine exposed areas in ShanXi Province, China
This study aimed to investigate the effects of fluorine and ADAMTS14_rs4747096 on bone mineral density (BMD). The survey was explored in a cross-sectional case-control study conducted in Shanxi, China. The BMD was measured by an ultrasonic bone mineral density instrument. The urine fluoride concentration was detected using the fluoride ion electrode. ADAMTS14_rs4747096 polymorphism was examined by multiplex polymerase chain reaction (PCR) and sequencing. The multinomial logistic regressions found that the urine fluoride was a risk factor for osteopenia (OR = 1.379, 95% CI: 1.127-1.687, P = 0.0018), osteoporosis (OR = 1.480...
Source: Environmental Science and Pollution Research International - September 19, 2023 Category: Environmental Health Authors: Ming Qin Yue Gao Meichen Zhang Junhua Wu Yang Liu Yuting Jiang Xiaodi Zhang Xin Wang Yanmei Yang Yanhui Gao Source Type: research
The government-production nexus of energy efficiency in China's construction industry: regional difference and factor analysis
Environ Sci Pollut Res Int. 2023 Sep 19. doi: 10.1007/s11356-023-29470-0. Online ahead of print.ABSTRACTFor decades, the construction industry has contributed significantly to China's economic growth. The heavy energy consumption inevitably leads to the release of large amounts of carbon emissions. Improving energy efficiency has been a crucial solution for mitigating the environmental impacts while boosting its green economy in the construction industry. Measuring the energy efficiency in the construction industry considering the quality of government sector is still limited. Using panel provincial data in China from 2011...
Source: Environmental Science and Pollution Research International - September 19, 2023 Category: Environmental Health Authors: Xin Feng Ruiqi Jin Yung-Ho Chiu Lina Zhang Source Type: research
Evaluation of genetic variants in ferroptosis-related genes and house dust mite-induced allergic rhinitis risk
CONCLUSIONS: These findings suggest that the genetic variants in ferroptosis-related genes ENPP2 and EPAS1 may increase HDM-induced AR risk and serve as potential predictors of HDM-induced AR susceptibility.PMID:37724950 | DOI:10.1016/j.intimp.2023.109707
Source: International Immunopharmacology - September 19, 2023 Category: Allergy & Immunology Authors: Yi-Fan Yang Rui Zheng Xiang Gu Fang Gao Min Chen Mu-Long Du Zheng-Dong Zhang Mei-Ping Lu Lei Cheng Source Type: research
A large survey on COVID-19 vaccination in patients with Parkinson's disease and healthy population
CONCLUSIONS: The COVID-19 vaccination rate was remarkably lower in PD patients than healthy individuals in China. The approved vaccines have shown an acceptable safety profile. Our findings would offer a reference to guide future clinical decision-making of COVID-19 vaccination and improve the immunization management of PD patients.PMID:37726180 | DOI:10.1016/j.vaccine.2023.09.002
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Chao Han Zhen Zhen Zhao Piu Chan Fang Li Chun Ling Chi Xin Zhang Yan Zhao Jing Chen Jing Hong Ma Source Type: research
Alteromonas Aquimaris sp. nov., Isolated from Surface Seawater
Curr Microbiol. 2023 Sep 19;80(11):343. doi: 10.1007/s00284-023-03472-0.ABSTRACTA Gram-negative, aerobic, motile by flagellum, and rod-shaped bacterium, designated ASW11-7T, was isolated from coastal surface seawater sample collected from the Yellow Sea, PR China. Strain ASW11-7T grew optimally at 37℃, 4.0% (w/v) NaCl and pH 7.0. Phylogenetic analysis based on the 16S rRNA gene sequences revealed that strain ASW11-7T belongs to the genus Alteromonas and most closely related to Alteromonas ponticola MYP5T (99.6% similarity), followed by Alteromonas confluentis DSSK2-12T (98.2%), Alteromonas lipolytica JW12T (98.2%), and A...
Source: Current Microbiology - September 19, 2023 Category: Microbiology Authors: Qin Wang Xin-Yuan Hu Li-Ping Sun Hui-Jing Niu Cai-Xia Pei Yi Li Cheng-Qiang Xia Source Type: research
Association of shift work with oxidative stress and alteration of fasting plasma glucose level in Chinese adults
CONCLUSIONS: These findings suggest that shift work is positively associated with blood glucose, and the association is partially mediated by oxidative stress.PMID:37724057 | DOI:10.1002/oby.23845
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Wenzhen Li Xiaobing Feng Haozhe Zhang Yi-Xin Wang Qiang Zeng Chong Liu Victor W Zhong Dongming Wang Source Type: research
