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Effects of PCSK9 inhibitors on coronary microcirculation, inflammation and cardiac function in patients with CHD after PCI: a protocol for systematic review and meta-analysis
This study is a systematic review of published literature data and no special ethical approval was required. PROSPERO registration number CRD42022346189.
Source: BMJ Open - September 18, 2023 Category: General Medicine Authors: Ye, X., Wang, S., Liu, X., Wu, Q., Lv, Y., Lv, Q., Li, J., Li, L., Yang, Y. Tags: Open access, Cardiovascular medicine Source Type: research

Effectiveness of Shuxuening injection in coronary heart disease: a systematic review and meta-analysis
Conclusion: SXNI can effectively improve angina symptoms, clinical efficacy, cardiac function, blood lipid indicators, and thrombosis factors of patients with CHD. However, more multi-center and large-sample studies are needed to confirm the conclusions due to the limitations of this study.Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=399606; Identifier: CRD42023433292.
Source: Frontiers in Pharmacology - September 18, 2023 Category: Drugs & Pharmacology Source Type: research

Genetic diversity and molecular evolution of Seoul virus in Hebei province, China
Infect Genet Evol. 2023 Sep 15:105503. doi: 10.1016/j.meegid.2023.105503. Online ahead of print.ABSTRACTSeoul virus (SEOV) is a major pathogen which causes hemorrhagic fever with renal syndrome (HFRS), and is present all over the world. However, there are currently few long-term systematic studies of SEOV's phylogenetic and evolutionary mechanisms in epidemic areas. Thus, in this study, we used RT-PCR combined with NGS to obtain the genomes of six SEOV viruses from 1993, as well as 56 Hebei province-specific tissue samples from 1999 to 2022. Phylogenetic analysis showed that the SEOV samples could be divided into seven gro...
Source: Infection, Genetics and Evolution - September 17, 2023 Category: Genetics & Stem Cells Authors: Yamei Wei Yanan Cai Xu Han Zhanying Han Yanbo Zhang Yonggang Xu Qi Li Source Type: research

Epidemiological characteristics of centenarian deaths in China during 2013-2020: A trend and subnational analysis
CONCLUSIONS: Unlike other countries, centenarian deaths in China are characterized by a higher proportion of home and heart disease deaths, and this death pattern differs across provinces.PMID:37718285 | DOI:10.1097/CM9.0000000000002823
Source: Chinese Medical Journal - September 17, 2023 Category: General Medicine Authors: Fan Mao Weiwei Zhang Peng Yin Lijun Wang Jinling You Jiangmei Liu Yunning Liu Maigeng Zhou Source Type: research

Prognostic and clinical value of circPRKCI expression in diverse human cancers
CONCLUSION: Elevated circPRKCI expression was correlated with worse OS and unfavorable clinical features, suggesting a novel prognostic and predictive role of circPRKCI in diverse human cancers.PMID:37718264 | DOI:10.1097/CM9.0000000000002844
Source: Chinese Medical Journal - September 17, 2023 Category: General Medicine Authors: Zhongyue Liu Xiaolei Ren Zhimin Yang Lin Mei Wenyi Li Chao Tu Zhihong Li Source Type: research

Improved clinical outcomes in advanced hepatocellular carcinoma treated with transarterial chemoembolization plus atezolizumab and bevacizumab: a bicentric retrospective study
CONCLUSIONS: Compared with Atez/Bev treatment, TACE-Atez/Bev showed better OS, PFS, and ORR for Chinese patients with advanced HCC, with an acceptable safety profile.PMID:37718456 | DOI:10.1186/s12885-023-11389-x
Source: Cancer Control - September 17, 2023 Category: Cancer & Oncology Authors: Fei Cao Changsheng Shi Guofu Zhang Jun Luo Jiaping Zheng Weiyuan Hao Source Type: research

Combined Use of Tumor Markers in Gastric Cancer: A Novel Method with Promising Prognostic Accuracy and Practicality
CONCLUSION: The combined use of tumor markers significantly improved the prognostic value compared with using a single tumor marker. The survival prediction model including the combined tumor markers was accurate and effective.PMID:37718336 | DOI:10.1245/s10434-023-14194-9
Source: Ann Oncol - September 17, 2023 Category: Cancer & Oncology Authors: Ruopeng Zhang Xiaojiang Chen Guoming Chen Zhoukai Zhao Yicheng Wei Feiyang Zhang Jun Lin Runcong Nie Yingbo Chen Source Type: research

Quantitative Evidence of the effect of Baduanjin exercise on quality of life and cardiac function in adults with chronic heart failure
CONCLUSION: Evidence from the meta-analysis support the beneficial effects of Baduanjin exercise on the QoL, cardiac function, and VO2max in patients with CHFin China. For optimal QoL improvements, it is recommended to engage in Baduanjin exercise 5-7 times per week for 30-60 min, over a duration of at least 8 weeks. In terms of NT-Pro BNP, Baduanjin exercise sessions of 30-60 min, 2-7 times per week, for a minimum of 8 weeks are recommended.PMID:37717550 | DOI:10.1016/j.ctcp.2023.101775
Source: Complementary Therapies in Clinical Practice - September 17, 2023 Category: Complementary Medicine Authors: Bowei Mei Lulu Yuan Yankai Shu Source Type: research

Product maturation and antibiotic resistance genes enrichment in food waste digestate and Chinese medicinal herbal residues co-composting
This study proposed co-composting of Chinese medicinal herbal residues (CMHRs) and FWD as a means to improve the maturation performance and investigated the evolution of antibiotic resistance genes (ARGs). Results demonstrated that CMHRs addition effectively accelerated the maturity of FWD composting to less than 35 days, remarkably removed its remaining antibiotics by 83.0% and promoted the formation of humification substances. However, both quantitative PCR and 16S rRNA sequencing analysis indicated that a significant enrichment of ARGs and mobile genetic elements including frA1, tetX, blaTEM, InuB-01, aadA2-02 and IntI-...
Source: Bioresource Technology - September 17, 2023 Category: Biotechnology Authors: Mengyu Cai Guihan Dong Yuting Zhou Caiyun Yang Hao Wu Chunyu Guo Haoran Zhang Ying Han Source Type: research

Do clean energy technologies, ecotourism, health policy, and green education help in achieving sustainability in China?
Environ Sci Pollut Res Int. 2023 Sep 18. doi: 10.1007/s11356-023-29680-6. Online ahead of print.ABSTRACTSustainable development has become the foremost requirement for sustainable economic conditions all around the globe, and this aspect demands new literature and regulators' emphasis. Hence, the present research investigates the impact of clean energy technologies, human development, health policies, green education, and ecotourism policy on sustainable development in China from 1991 to 2021. The researchers investigate the association among the variables using dynamic autoregressive distributed lag (DARDL). The outcomes ...
Source: Environmental Science and Pollution Research International - September 17, 2023 Category: Environmental Health Authors: Kuanlei Wang Wenjuan Yu Xiao Song Source Type: research

Urbanization, rural energy-poverty, and carbon emission: unveiling the pollution halo effect in 48 BRI countries
Environ Sci Pollut Res Int. 2023 Sep 18. doi: 10.1007/s11356-023-29861-3. Online ahead of print.ABSTRACTThe Belt and Road Initiative (BRI) is a significant economic development strategy directed by China. Its primary objective is to establish connectivity across a vast region encompassing over 70 countries in Asia, Europe, and Africa. This endeavor significantly impacts worldwide development, economic advancement, and environmental sustainability. Nevertheless, insufficient pertinent evidence exists when exploring the correlation between urbanization, rural energy poverty (Rural_EP), and carbon emissions (CO2_Em) in the BR...
Source: Environmental Science and Pollution Research International - September 17, 2023 Category: Environmental Health Authors: Qi Xu Salim Khan Xiaojuan Zhang Muhammad Usman Source Type: research

Occurrence, tissue distribution, and risk assessment of progestins, androgens, estrogens, and phenols in wild freshwater fish species
Environ Sci Pollut Res Int. 2023 Sep 18. doi: 10.1007/s11356-023-29889-5. Online ahead of print.ABSTRACTThe presence of endocrine-disrupting chemicals (EDCs) in aquatic environments such as water, sediment, and sludge received more and more attention. However, the bioaccumulate properties of EDCs, particularly progestins and androgens, in various tissues of different wild freshwater fish species, as well as their effects on human health, have not been fully studied. The muscle, liver, and gills of three wild fish species obtained from the East Dongting Lake in southern China were examined for the presence of 19 EDCs (4 pro...
Source: Environmental Science and Pollution Research International - September 17, 2023 Category: Environmental Health Authors: Xinyi Zhou Zhaoguang Yang Fangyuan Peng Yang Liu Yi Lu Haipu Li Source Type: research

The combined effects of nitrogen fertilizer and biochar on soil aggregation, N < sub > 2 < /sub > O emission, and yield from a vegetable field in southeastern China
This study aims to evaluate the combined effects of biochar and nitrogen (N) fertilizer on soil aggregation, nitrous oxide (N2O) emission, global warming potential (GWP), vegetable yield, and greenhouse gas intensity (GHGI). The experiments were conducted in a vegetable field with two consecutive vegetable crops in 2019 and 2020 in southeastern China. There were four treatments: control (CK), conventional N fertilizer (U), biochar applied at 15 t ha-1 with N fertilizer (UB1), and biochar applied at 30 t ha-1 with N fertilizer (UB2). The results indicate that while N application significantly increased N2O emission of the v...
Source: Environmental Science and Pollution Research International - September 17, 2023 Category: Environmental Health Authors: Ying Han Jing Ma Xianghua Xu Xinyu Lu Ziyao Wang Liying Sun Source Type: research

Causal effects of appearance-related social exclusion on state body dissatisfaction among young Chinese adults
CONCLUSIONS: Social exclusion experiences linked to physical appearance are a significant causal influence on increases in state BD and positive mood decrements among young Chinese adults.PMID:37717555 | DOI:10.1016/j.actpsy.2023.104032
Source: Acta Psychologica - September 17, 2023 Category: Psychiatry & Psychology Authors: Tong Chao Todd Jackson Source Type: research

Recent engineering advances of EVs for compounds, nucleic acids, and TCM delivery
Eur J Pharm Sci. 2023 Sep 15:106584. doi: 10.1016/j.ejps.2023.106584. Online ahead of print.ABSTRACTExtracellular vesicles (EVs) are phospholipid bilayer nano-vesicles that were originally identified to deliver signals for intercellular communications. Based on the dynamic contents including proteins, nucleic acids and metabolites, EVs have been developed into diagnostic and therapeutic fields including cardiovascular diseases, neurological disorders and infectious diseases. A growing number of investigations revealed that EVs are also powerful carriers of loaded compounds and nucleic acids as enhanced treatments. Herein, ...
Source: European Journal of Pharmaceutical Sciences - September 17, 2023 Category: Drugs & Pharmacology Authors: Yunfeng Di Wei Wang Yong Wang Jingyu Wang Source Type: research