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Total 6127 results found since Jan 2013.

Novel therapies for food allergy: The search continues
The multifaceted burden that food allergy places on patients and families has long been recognized by allergists; it encompasses not only epidemiologic and economic elements, but also significant dietary, and psychosocial components, resulting in decreased quality of life. Ongoing efforts to develop active treatments for this chronic disease have led to food oral immunotherapy (OIT), a therapy that has high efficacy, a good safety profile and the potential to raise the allergenic threshold of reactivity, reduce severity of allergic reactions and improve quality of life.
Source: Annals of Allergy, Asthma and Immunology - June 30, 2023 Category: Allergy & Immunology Authors: Aikaterini Anagnostou, Julia Upton, Anna Nowak-Wegrzyn Tags: Editorial Source Type: research

Is there a rationale for supplementing with vitamin D patients under treatment with allergen immunotherapy?
Ann Med. 2023 Dec;55(1):2230864. doi: 10.1080/07853890.2023.2230864.ABSTRACTVitamin D (VD) has been shown to exert immunomodulatory activities, especially in promoting immune tolerance. For these properties VD has been proposed in the therapy of immunological conditions in which the loss of tolerance is the key pathogenetic aspect of the disease, such as allergies. Despite these properties available literature suggests VD is not useful in treating or preventing allergic diseases and whether low serum VD levels favor allergic sensitization and severity is debated. The level of VD is one of the many conditions that can influ...
Source: Annals of Medicine - June 30, 2023 Category: Internal Medicine Authors: Mario Di Gioacchino Claudia Petrarca Loredana Della Valle Rocco Mangifesta Francesca Santilli Source Type: research

Allergy to the cat —from diagnosis to management
ConclusionIn this review, we present current literature and facts that should make everyday life easier for patients, even without giving up the animal. We also review best practices in the management of cat allergy and present new management options and concepts from the development pipeline that our patients are eagerly awaiting.
Source: Allergo Journal International - June 30, 2023 Category: Allergy & Immunology Source Type: research

Increase in the prevalence of follicular regulatory T cells correlates with clinical efficacy of sublingual immunotherapy with house dust mites
CONCLUSIONAn increase in Tfr cells may play an important role in SLIT, and may be a useful indicator for the clinical efficacy of SLIT.This article is protected by copyright. All rights reserved
Source: International Forum of Allergy and Rhinology - June 22, 2023 Category: Allergy & Immunology Authors: Takuya Murao, Hideaki Kouzaki, Hiroyuki Arai, Koji Matsumoto, Keigo Nakamura, Kento Kawakita, Ichiro Tojima, Shino Shimizu, Atsushi Yuta, Takeshi Shimizu Tags: ORIGINAL ARTICLE Source Type: research

Peanut allergy in toddlers
We know that nearly a third of children with peanut allergy will outgrow their response by the age of six and if you introduce peanut protein as early as 4–6 months of age, this will substantially reduce the development of peanut allergy later in childhood. Is there a role for desensitisation and can desensitisation work in children less than 4 years of age? Greenhawt M et al [N Engl J Med 2023; 388:1755–1766 DOI: 10.1056/NEJMoa2212895] enrolled 362 children, aged 1–3 years with peanut allergy in a multicentre, double-blind, randomised, placebo-controlled trial; the phase 3 Epicutaneous Immunotherapy in T...
Source: Archives of Disease in Childhood - June 19, 2023 Category: Pediatrics Tags: Miscellanea Source Type: research

Study of stereotyped, allergen-specific IgE sequences from specific immunotherapy participants yields new insight into mechanisms of allergy suppression
Source: Journal of Allergy and Clinical Immunology - June 19, 2023 Category: Allergy & Immunology Authors: Tracy A. Hwangpo, Harry W. Schroeder Source Type: research

Objective evaluation of sublingual immunotherapy for pediatric allergic rhinitis respond to sq house dust mite
CONCLUSION: The present study showed a decrease in scores not only for subjective assessments but also for objective evaluation methods, the house dust nasal provocation test and the nasal airway resistance.PMID:37316242 | DOI:10.15036/arerugi.72.375
Source: Arerugi - June 14, 2023 Category: Allergy & Immunology Authors: Takanari Kawabe Kayoko Kawashima Mika Okuno Masashi Yamamoto Takahiro Sasaki Yukiko Hanada Shohei Tanaka Junko Kumon Tomohiro Yamaguchi Rumi Ueno Yuki Tsurinaga Youhei Fukazawa Amane Shigekawa Yuri Takaoka Yukinori Yoshida Makoto Kameda Source Type: research

Updates in the diagnosis and practical management of allergic rhinitis
Expert Rev Clin Pharmacol. 2023 Jun 14. doi: 10.1080/17512433.2023.2225770. Online ahead of print.ABSTRACTINTRODUCTION: Allergic rhinitis (AR) is a widespread disease that can be associated with other conditions, including conjunctivitis, rhinosinusitis, asthma, food allergy and atopic dermatitis. Diagnosis is based on history and documentation of sensitization, such as the production of allergen-specific IgE, preferably using molecular diagnostics. Treatments are based on patient education, non-pharmacological and pharmacological remedies, allergen-specific immunotherapy (AIT), and surgery. Symptomatic treatments mainly c...
Source: Expert Review of Clinical Pharmacology - June 14, 2023 Category: Drugs & Pharmacology Authors: Chiara Trincianti Maria Angela Tosca Giorgio Ciprandi Source Type: research

Objective evaluation of sublingual immunotherapy for pediatric allergic rhinitis respond to sq house dust mite
CONCLUSION: The present study showed a decrease in scores not only for subjective assessments but also for objective evaluation methods, the house dust nasal provocation test and the nasal airway resistance.PMID:37316242 | DOI:10.15036/arerugi.72.375
Source: Allergology International - June 14, 2023 Category: Allergy & Immunology Authors: Takanari Kawabe Kayoko Kawashima Mika Okuno Masashi Yamamoto Takahiro Sasaki Yukiko Hanada Shohei Tanaka Junko Kumon Tomohiro Yamaguchi Rumi Ueno Yuki Tsurinaga Youhei Fukazawa Amane Shigekawa Yuri Takaoka Yukinori Yoshida Makoto Kameda Source Type: research

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