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Therapy: Immunotherapy
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A Skin Patch Shows Promise in Treating Kids ’ Peanut Allergies
WASHINGTON — An experimental skin patch is showing promise to treat toddlers who are highly allergic to peanuts—training their bodies to handle an accidental bite.
Peanut allergy is one of the most common and dangerous food allergies. Parents of allergic tots are constantly on guard against exposures that can turn birthday parties and play dates into emergency room visits.
There is no cure. The only treatment is for children 4 and older who can consume a special peanut powder to protect against a severe reaction.
The patch, named Viaskin, aims to deliver that kind of treatment through the skin instead. In a maj...
Source: TIME: Health - May 11, 2023 Category: Consumer Health News Authors: LAURAN NEERGAARD—AP Tags: Uncategorized Diet & Nutrition healthscienceclimate wire Source Type: news
Skin Patch Could Help Ease Peanut Allergy in Toddlers
THURSDAY, May 11, 2023 -- A " peanut patch " worn on the skin may help protect toddlers who have potentially life-threatening peanut allergies, a new clinical trial shows.
The patch is a form of immunotherapy, which means it exposes peanut-allergic...
Source: Drugs.com - Daily MedNews - May 11, 2023 Category: General Medicine Source Type: news
Immunotherapy Works Well for Young Children With Peanut Allergy
WEDNESDAY, May 10, 2023 -- For children aged 1 to 3 years with peanut allergy, epicutaneous immunotherapy for 12 months is superior for desensitizing children to peanuts, according to a study published in the May 11 issue of the New England Journal...
Source: Drugs.com - Pharma News - May 10, 2023 Category: Pharmaceuticals Source Type: news
Why Allergy Seasons Are Getting Worse
If you’ve been itchy, congested, and sneezy for months, you’re not alone. This year’s spring allergy season started early, broke pollen-count records in some parts of the country, and is still going strong in many areas.
Unfortunately, this year is unlikely to be a fluke. While pollen counts vary from year to year, recent trends suggest allergy seasons are, in general, getting longer and worse, says Dr. Kristine Vanijcharoenkarn, an assistant professor at Emory University School of Medicine who specializes in allergies and immunology. Patients started filling her office early this year, around the beginni...
Source: TIME: Health - May 9, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Environment healthscienceclimate Source Type: news
Eruption of Permanent Teeth As Risk Factor for Allergic Reactions During Oral Immunotherapy
Pediatric Allergy, Immunology, and Pulmonology, Ahead of Print.
Source: Pediatric, Allergy, Immunology, and Pulmonology - May 9, 2023 Category: Respiratory Medicine Authors: Francesca Mori Benedetta Pessina Mattia Giovannini Giulia Liccioli Lucrezia Sarti Erika Paladini Leonardo Tomei Simona Barni Source Type: research
Equine allergic skin diseases: Clinical consensus guidelines of the World Association for Veterinary Dermatology
CONCLUSIONS AND CLINICAL RELEVANCE: Insect bite hypersensitivity (IBH) is the best characterised allergic skin disease. An immunoglobulin (Ig)E response against Culicoides salivary antigens is widely documented. Genetics and environmental factors play important roles. Tests with high sensitivity and specificity are lacking, and diagnosis of IBH is based on clinical signs, seasonality and response to insect control. Eosinophils, interleukin (IL)-5 and IL-31 are explored as therapeutic targets. Presently, the most effective treatment is insect avoidance. Existing evidence does not support allergen-specific immunotherapy (ASI...
Source: Veterinary Dermatology - May 8, 2023 Category: Veterinary Research Authors: R Marsella S White V A Fadok D Wilson R Mueller C Outerbridge W Rosenkrantz Source Type: research
Allergy Immunotherapy: State of the Art
AbstractPurpose of ReviewThis paper is intended to review the current status of allergy immunotherapy (AIT), administered subcutaneously (SCIT) or sublingually (SLIT), for the treatment of allergic respiratory disease.Recent FindingsSystematic reviews and meta-analyses confirm the efficacy of SCIT for allergic rhinitis (AR), allergic asthma (AA), and for Hymenoptera venom sensitivity, while SLIT is clearly effective for AR, but the data is marginal for AA. An exception is the house dust mite SLIT-tablet which has reduced inhaled steroid use and asthma exacerbations and improved asthma control in placebo-controlled trials. ...
Source: Current Treatment Options in Allergy - May 6, 2023 Category: Allergy & Immunology Source Type: research
The need for change: Lessons learned from Food and Drug Administration-approved peanut oral immunotherapy
Ann Allergy Asthma Immunol. 2023 May;130(5):542-543. doi: 10.1016/j.anai.2023.01.031.NO ABSTRACTPMID:37137601 | DOI:10.1016/j.anai.2023.01.031
Source: Annals of Allergy, Asthma and Immunology - May 3, 2023 Category: Allergy & Immunology Authors: S Shahzad Mustafa Douglas P Mack Source Type: research
Cluster immunotherapy: Don't rush to judgment
Ann Allergy Asthma Immunol. 2023 May;130(5):536-537. doi: 10.1016/j.anai.2023.01.022.NO ABSTRACTPMID:37137598 | DOI:10.1016/j.anai.2023.01.022
Source: Annals of Allergy, Asthma and Immunology - May 3, 2023 Category: Allergy & Immunology Authors: Jonathan Matz David B K Golden Source Type: research
The need for change: Lessons learned from Food and Drug Administration-approved peanut oral immunotherapy
Ann Allergy Asthma Immunol. 2023 May;130(5):542-543. doi: 10.1016/j.anai.2023.01.031.NO ABSTRACTPMID:37137601 | DOI:10.1016/j.anai.2023.01.031
Source: Annals of Allergy, Asthma and Immunology - May 3, 2023 Category: Allergy & Immunology Authors: S Shahzad Mustafa Douglas P Mack Source Type: research
Cluster immunotherapy: Don't rush to judgment
Ann Allergy Asthma Immunol. 2023 May;130(5):536-537. doi: 10.1016/j.anai.2023.01.022.NO ABSTRACTPMID:37137598 | DOI:10.1016/j.anai.2023.01.022
Source: Annals of Allergy, Asthma and Immunology - May 3, 2023 Category: Allergy & Immunology Authors: Jonathan Matz David B K Golden Source Type: research
Peanut allergy: risk factors, immune mechanisms, and best practices for oral immunotherapy success
Expert Rev Clin Immunol. 2023 May 5:1-11. doi: 10.1080/1744666X.2023.2209318. Online ahead of print.ABSTRACTINTRODUCTION: Peanut oral immunotherapy (pOIT) is the only FDA-approved treatment for food allergy and its adoption amongst allergist immunologists and their patients is growing. pOIT is the subject of numerous clinical trials, however, the focus is often on treatment efficacy, safety, and tolerability, rather than identifying patients most likely to benefit from pOIT. Here, we review existing data on the clinical and immunological outcomes of pOIT that inform best practices for pOIT candidate selection.AREAS COVERED...
Source: Expert Review of Clinical Immunology - May 2, 2023 Category: Allergy & Immunology Authors: Jyothi Tirumalasetty Suzanne Barshow Laurie Kost Lu Morales Reyna Sharma Carlos Lazarte Kari C Nadeau Source Type: research
