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Therapy: Immunotherapy
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Total 6127 results found since Jan 2013.
Insights into mechanisms of immunotherapy circa 1943: "What has been will be again"
Ann Allergy Asthma Immunol. 2023 Aug;131(2):277-278. doi: 10.1016/j.anai.2023.01.035.NO ABSTRACTPMID:37536876 | DOI:10.1016/j.anai.2023.01.035
Source: Annals of Allergy, Asthma and Immunology - August 3, 2023 Category: Allergy & Immunology Authors: Larry Borish Source Type: research
Insights into mechanisms of immunotherapy circa 1943: “What has been will be again”
Commentary on: “The presence of thermostable inhibiting factor in the sera of patients treated for hay fever by injections of pollen extract.” Annals of Allergy. May-June, 1944, pp. 207-229. Ethan Allen Brown, MD, and Captain Eugene M Holden, MD.1
Source: Annals of Allergy, Asthma and Immunology - August 1, 2023 Category: Allergy & Immunology Authors: Larry Borish Tags: Special Perspective Source Type: research
Intra-cervical lymphatic immunotherapy for dust mite-induced allergic rhinoconjunctivitis in children: a 3-year prospective randomized controlled trial
ConclusionICLIT could ameliorate significantly the allergic symptoms in pediatric patients with an advantage in effectiveness and safety, besides an improved life quality including shortened period of treatment, frequency of drug use and pain perception.Clinical trial registrationhttps://www.chictr.org.cn/, identifier ChiCTR1800017130.
Source: Frontiers in Immunology - August 1, 2023 Category: Allergy & Immunology Source Type: research
Advancing Precision Medicine in Asthma: Evolution of Treatment Outcomes
The article discusses the historical evolution of asthma treatment and highlights recent advancements in personalized medicine, specifically the use of biologics in severe asthma therapy and its potential combination with allergen immunotherapy (AIT). One of the major breakthroughs of biologics is their potential effect on airway remodeling, a crucial aspect of asthma chronicity. The article introduces the concept of Disease Modifying Anti Asthmatic Drugs (DMAADs), which aim to modify the course of asthma and possibly modulate or prevent airway remodeling.
Source: Journal of Allergy and Clinical Immunology - July 30, 2023 Category: Allergy & Immunology Authors: G.W. Canonica, G. Varricchi, G. Paoletti, E. Heffler, J.C. Virchow Source Type: research
Evaluation of Molecular-level Changes of Programmed Cell Death Ligand-1 after Radiation Therapy in a BALB/c CT26 Colorectal Mouse Tumor Model
In this study, female BALB/c mice inoculated with CT26 tumor cells were irradiated with 3 different RT regimens using the same BED of 40 gray (Gy). These included ablative RT (1*15 Gy), hypo-fractionated RT (2*10 Gy), and conventional (Hyper-fractionated) RT (10*3 Gy). PD-L1 expression was analyzed with immunohistochemical staining on days 2 and 20 and when the size of tumors had reached 2 cm2 after RT. All treated groups expressed PD-L1, but the group receiving single ablative high-dose RT showed higher expression compared to the other groups. No significant differences in PD-L1 expression were observed at different times...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 27, 2023 Category: Allergy & Immunology Authors: Fateme Khani Chamani Mahdi Shabani Afshin Moradi Maedeh Alinejad Seyed Amir Jalali Source Type: research
A short, safe rush-induction protocol for aeroallergen immunotherapy
Ann Allergy Asthma Immunol. 2023 Jul 24:S1081-1206(23)00521-5. doi: 10.1016/j.anai.2023.07.016. Online ahead of print.NO ABSTRACTPMID:37495014 | DOI:10.1016/j.anai.2023.07.016
Source: Annals of Allergy, Asthma and Immunology - July 26, 2023 Category: Allergy & Immunology Authors: Monica Hajirawala Amber Hardeman Margaret P Huntwork John C Carlson Source Type: research
T cell subsets in allergy and tolerance induction
This article is protected by copyright. All rights reserved.PMID:37489248 | DOI:10.1002/eji.202249983
Source: European Journal of Immunology - July 25, 2023 Category: Allergy & Immunology Authors: Ina Suhrkamp Alexander Scheffold Guido Heine Source Type: research
A short, safe rush-induction protocol for aeroallergen immunotherapy
A four-step rush-induction protocol that ends with 0.05mL of the 1:10v/v concentration is safe for patients initiating aeroallergen immunotherapy (AIT). Rush induction protocols ending with higher doses carry a greater risk of systemic allergic reactions, particularly for those with asthma.
Source: Annals of Allergy, Asthma and Immunology - July 24, 2023 Category: Allergy & Immunology Authors: Monica Hajirawala, Amber Hardeman, Margaret P. Huntwork, John C. Carlson Tags: Letters Source Type: research
