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Therapy: Immunotherapy
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Total 6127 results found since Jan 2013.
An Overview of Nanotechnological Approaches for the Diagnosis and Treatment of Allergic Illness
Curr Pharm Des. 2023 Aug 28. doi: 10.2174/1381612829666230828104015. Online ahead of print.ABSTRACTAllergies are a major health issue. Allergen avoidance, antihistamines, and corticosteroids do not treat the pathology's causes, therefore long-term therapy is essential. Long-term allergen-specific immunotherapy builds immune tolerance to the allergen. Unfortunately, immunotherapies for all allergens are not available, and adverse reactions during therapy, especially in severely allergic persons, remain a worry. In this regard, cell and bio- or nanomaterial-based allergy treatments are promising. This overview covers the mos...
Source: Current Pharmaceutical Design - August 29, 2023 Category: Drugs & Pharmacology Authors: Bhupendra Sharma Rohitas Deshmukh Source Type: research
The Role of IgA in the Manifestation and Prevention of Allergic Immune Responses
AbstractPurpose of ReviewImmunoglobulin A (IgA) mediates immune exclusion of antigens in the gut. Notably, IgA plays also a role in the prevention of IgE-mediated allergies and induction of immune tolerance. The present review addresses the role of IgA in the manifestation of IgE-mediated allergies, including allergen-specific immunotherapy (AIT), the regulation of IgA production, and the mechanism of IgA in immune cell activation.Recent FindingsThe majority of studies report an association of IgA with the induction of immune tolerance in IgE-mediated allergies. However, reports on the involvement of humoral and mucosal Ig...
Source: Current Allergy and Asthma Reports - August 23, 2023 Category: Allergy & Immunology Source Type: research
Anti-allergen monoclonal antibodies for the treatment of allergies
ConclusionThe development of anti-allergen antibody therapies offers great potential for the treatment of allergies. Of interest, the efficacy of passive immunization approaches will likely extend beyond allergen neutralization as in the presence of the allergen they might contribute to long-lasting disease modification.
Source: Allergo Journal International - August 15, 2023 Category: Allergy & Immunology Source Type: research
Peanut Oral Immunotherapy Effective for Children Under 12 Months
MONDAY, Aug. 14, 2023 -- Peanut oral immunotherapy (OIT) can induce desensitization to peanuts in children younger than 12 months of age, according to research published online July 13 in the Journal of Allergy and Clinical Immunology: In...
Source: Drugs.com - Pharma News - August 14, 2023 Category: Pharmaceuticals Source Type: news
Efficacy of Sublingual Immunotherapy in Allergic Rhinitis Patients with Asthma: A Systematic Review and Meta-Analysis
CONCLUSION: SLIT may be a therapeutic method for improving rhinitis symptoms and asthma symptoms in AR patients with asthma. However, as there was significant heterogeneity in results, more high-quality and well-designed studies are needed in the future to elucidate the efficacy of SLIT.PMID:37559376 | DOI:10.1177/19458924231193528
Source: American Journal of Rhinology and Allergy - August 10, 2023 Category: ENT & OMF Authors: Dijiang Ma Qiling Zheng Jianing Sun Shenjun Tang Wudan He Source Type: research
GSE231590 Identification of cow milk epitopes to characterize and quantify disease-specific T cells in allergic children
Contributors : Sloan A Lewis ; Aaron Sutherland ; Ferran Soldevilla ; Luise Westernberg ; Minori Aoki ; April Frazier ; Synaida Maiche ; Mich Erlewyn-Lajeunesse ; Hasan Arshad ; Stephanie Leonard ; Susan Laubach ; Jennifer A Dantzer ; Robert A Wood ; Alessandro Sette ; Gregory Seumois ; Pandurangan Vijayanand ; Bjoern PetersSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCow milk (CM) allergy is the most prevalent food allergy in young children in the US and Great Britain. Current diagnostic tests are either unreliable (IgE, skin prick test), or resource-intensive with risks (food cha...
Source: GEO: Gene Expression Omnibus - August 10, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Study Confirms That Exposure Therapy in Infancy Can Stop Peanut Allergy
MONDAY, Aug. 7, 2023 -- Early and gradual exposure to peanuts under medical supervision curbed infants ' allergies, according to a new study.
While researchers had seen that peanut oral immunotherapy was well tolerated by toddlers, this research...
Source: Drugs.com - Daily MedNews - August 7, 2023 Category: General Medicine Source Type: news
Insights into mechanisms of immunotherapy circa 1943: "What has been will be again"
Ann Allergy Asthma Immunol. 2023 Aug;131(2):277-278. doi: 10.1016/j.anai.2023.01.035.NO ABSTRACTPMID:37536876 | DOI:10.1016/j.anai.2023.01.035
Source: Annals of Allergy, Asthma and Immunology - August 3, 2023 Category: Allergy & Immunology Authors: Larry Borish Source Type: research
