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Infectious Disease: Endemics

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Total 382 results found since Jan 2013.

Basophil allergen threshold sensitivity and component resolved diagnostics improve hazelnut allergy diagnosis
Conclusions & Clinical RelevanceCD‐sens and component resolved diagnostics to hazelnut, used separately or in combination may improve the diagnostic accuracy and safety and reduce over‐diagnosis of hazelnut allergy.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - February 1, 2015 Category: Allergy & Immunology Authors: J Brandström, A Nopp, S.G. O Johansson, G Lilja, A‐C Sundqvist, M. P Borres, C Nilsson Tags: Original Article‐Clinical Allergy Source Type: research

Ara h 2 and Ara 6 are the best predictors of severe peanut allergy: A double‐blind placebo‐controlled study
ConclusionCo‐sensitization to Ara h 2 and Ara h 6 was associated with severe reactions distinguishing severe allergy from mild symptoms. SIgE to Ara h 8 added no diagnostic value. Component‐resolved diagnostics reduce the need for oral challenges in peanut allergy.This article is protected by copyright. All rights reserved.
Source: Allergy - June 11, 2015 Category: Allergy & Immunology Authors: Anna Kaarina Kukkonen, Anna S. Pelkonen, Soili Mäkinen‐Kiljunen, Helena Voutilainen, Mika J. Mäkelä Tags: Original Article Source Type: research

Influence of Parasitic Worm Infections on Allergy Diagnosis in Sub-Saharan Africa
AbstractEpidemiological studies from Sub-Saharan Africa indicate that allergies are on the rise in this region especially in urban compared to rural areas. This increase has been linked to improved hygiene, lifestyle changes, and lower exposure to pathogens in childhood. Reduced exposure to parasitic worm (helminth) infections and allergy outcomes has been the focus of a number of population studies over the years. Paradoxically, there are parallels in the immune responses to helminths and to allergies. Both conditions are associated with elevated levels of immunoglobulin E, high numbers of T helper 2 cells, eosinophils, a...
Source: Current Allergy and Asthma Reports - September 1, 2017 Category: Allergy & Immunology Source Type: research

Global View on Ant Venom Allergy: from Allergenic Components to Clinical Management
This article provides a global view on allergic reactions to the venoms of stinging ants and the contemporary approach to diagnose and manage ant venom allergy.
Source: Clinical Reviews in Allergy and Immunology - June 1, 2021 Category: Allergy & Immunology Source Type: research

Component resolved diagnostics demonstrates that most peanut allergic individuals could potentially introduce tree nuts to their diet
Conclusions and clinical relevancePR‐10‐sensitizations were frequent and strong regardless of peanut allergy status. Component resolved diagnostics can be employed to demonstrate to patients that sensitization to seed storage proteins of tree nuts is uncommon. Several tree nuts could potentially be reintroduced to the diet.This article is protected by copyright. All rights reserved.
Source: Clinical and Experimental Allergy - January 29, 2018 Category: Allergy & Immunology Authors: Riikka Uotila, Anna Kaarina Kukkonen, W.Marty Blom, Ben Remington, Joost Westerhout, Anna Susanna Pelkonen, Mika Juhani M äkelä Tags: Original Article ‐Clinical Allergy Source Type: research

Basophil allergen threshold sensitivity and component‐resolved diagnostics improve hazelnut allergy diagnosis
Conclusions and Clinical RelevanceCD‐sens and component‐resolved diagnostics to hazelnut, used separately or in combination, may improve the diagnostic accuracy and safety and reduce overdiagnosis of hazelnut allergy.
Source: Clinical and Experimental Allergy - August 24, 2015 Category: Allergy & Immunology Authors: J. Brandström, A. Nopp, S. G. O. Johansson, G. Lilja, A.‐C. Sundqvist, M. P. Borres, C. Nilsson Tags: Original Article Source Type: research

Cross‐sensitization profiles of edible nuts in a birch‐endemic area
ConclusionBirch‐sensitized individuals are frequently co‐sensitized to hazelnut, almond, and peanut. Among the birch‐negatives, prevalences of nut sensitizations decrease from early childhood to adolescence. Cashew and pistachio, and pecan and walnut cross‐react the most.This article is protected by copyright. All rights reserved.
Source: Allergy - December 25, 2015 Category: Allergy & Immunology Authors: Riikka Uotila, Anna Kaarina Kukkonen, Anna Pelkonen, Mika J. Mäkelä Tags: Original Article: Experimental Allergy and Immunology Source Type: research

Time for Allergists to Consider the Role of Mouse Allergy in Non-Inner City Children with Asthma
Publication date: Available online 5 April 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Elissa M. Abrams, Stanley J. Szefler, Allan B. BeckerMouse allergen is endemic in the inner cities of the United States, with research predominantly in the Northeastern United States. A recent practice parameter notes the effect of mouse exposure in asthma in inner cities. However, studies are emerging that find a role of mouse allergen in non–inner cities as well. Mouse sensitization is associated with mouse allergen exposure and has been linked with adverse asthma outcomes including increased ast...
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 6, 2019 Category: Allergy & Immunology Source Type: research

From the Pages of Allergy Watch
For this installment of ‘From the Pages of Allergy Watch’ I've selected articles from the July-Aug issue. The first, reviewed by Dr Lee, suggests that pretreatment with H1& H2 antihistamines and montelukast can reduce the risk for reaction to COVID-19 vaccination. The next, reviewed by Dr Hernandez-Trujillo, reports data suggesting that alpha-gal allergy can be a problem even in areas not endemic for the lone star tick. The last article, reviewed by Dr Joshi, presented data suggesting that children with more severe atopic dermatitis are more likely to have learning disabilities.
Source: Annals of Allergy, Asthma and Immunology - September 17, 2021 Category: Allergy & Immunology Authors: Stanley Fineman, Gerald B. Lee, Vivian Hernandez-Trujillo, Shyam Joshi Tags: Special Series Source Type: research

Adherence to imported fire ant subcutaneous immunotherapy.
CONCLUSION: IFA SCIT is a life-saving therapy that is safe and effective. Despite this, only 71% followed the recommendation to start, and at 1 year only 35% remained adherent. Adherence was not statistically related to age, sex, or severity of initial reaction. Logistical constraints and fear were significant impediments. PMID: 23548525 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - March 1, 2013 Category: Allergy & Immunology Authors: Stokes SC, Quinn JM, Sacha JJ, White KM Tags: Ann Allergy Asthma Immunol Source Type: research

Topical mitomycin C as an adjunct to surgical debulking and medical treatment in rhinoscleroma.
CONCLUSION: Topical MMC may reduce granulation tissue and intranasal adhesion formation in patients with rhinoscleroma. Further studies with a larger number of samples and longer follow-up periods are recommended. PMID: 26163236 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - July 1, 2015 Category: ENT & OMF Authors: Awad OG, Hammad MS Tags: Am J Rhinol Allergy Source Type: research

Cutaneous larva migrans.
CONCLUSION: The pruritic serpiginous track is pathognomonic. Oral ivermectin is the treatment of choice. PMID: 28078983 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - January 14, 2017 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

Prediction of peanut allergy in adolescence by early childhood storage protein-specific IgE signatures: The BAMSE population-based birth cohort
One of the most frequent and severe forms of food allergy is caused by peanuts.1 IgE reactivity to peanut storage proteins, in particular to Arachis hypogaea (Ara h) 2, is associated with systemic reactions.2 However, in some regions, the lipid transfer protein Ara h 9 is an important allergen molecule, whereas in birch endemic areas, the pathogenesis-related protein family 10 protein Ara h 8 is a more common cross-reactive component.3
Source: Journal of Allergy and Clinical Immunology - February 10, 2017 Category: Allergy & Immunology Authors: Anna Asarnoj, Carl Hamsten, Christian Lupinek, Erik Mel én, Niklas Andersson, Josep M. Anto, Jean Bousquet, Rudolf Valenta, Marianne van Hage, Magnus Wickman, MeDALL Consortium Tags: Letter to the Editor Source Type: research

Sensitization to PR-10 proteins is indicative of distinctive sensitization patterns in adults with a suspected food allergy
ConclusionsSensitization to PR-10 food proteins could occur without concomitant sensitization to common PR-10 from pollen in a subset of subjects. Less commonly recognized PR-10 proteins appear to be an indication of polysensitization.
Source: Clinical and Translational Allergy - November 23, 2017 Category: Allergy & Immunology Source Type: research

Development and Evaluation of a Novel ELISA for Detection of Antibodies against HTLV-I Using Chimeric Peptides.
Abstract We aimed to develope a peptide-based indirect ELISA to detect antibodies against Human T-lymphotropic virus type I (HTLV-I). Two chimeric peptides (CP-1 and CP-2) were designed using linear immunodominant epitopes of gp-46-I, and gp21-I proteins, according to the sequence from Uniprot database. These peptides were studied initially in the ELISA using infected sera. The most promising peptideCP-1, was used to develop a peptide ELISA for detection of HTLV-I infected sera. The optimal conditions for CP-1ELISA were: the optimum coating buffer was 100mM NaHCO3, pH 9.6; coating peptide concentration was 10 µg/...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 1, 2018 Category: Allergy & Immunology Authors: Mosadeghi P, Heydari-Zarnagh H Tags: Iran J Allergy Asthma Immunol Source Type: research