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Source: European Respiratory Journal

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Total 2423 results found since Jan 2013.

High prevalence of sensitisation to house dust mite in ethnic minority severe asthma patients
Conclusion: sensitisation to HDM is more prevalent in EMG than White severe asthma patients, independently of deprivation index.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Kerks, J., Marsh, J., Bahron, A., Krishna, T., Walters, G., O'Riordan, F., White, L., Sullivan, J., Mansur, A. Tags: 05.03 - Allergy and immunology Source Type: research

Blood eosinophils activation type, besides count, associate with exacerbations in asthma
Conclusions: Besides the count, blood eosinophils surface receptor expression associates with exacerbations in asthma.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Vitiello, L., Mazzuca, C., Finamore, P., Zotti, S., Travaglini, S., Antonelli Incalzi, R., Scarlata, S., Scarlata, S. Tags: 05.03 - Allergy and immunology Source Type: research

Differentiation of severe versus mild/moderate asthma in children, using a new pilot registry
Conclusion: PREMIER can be a useful tool in assessing children with asthma, with the prospect of initiating biological agents.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Statha, E., Xepapadaki, P., Kothra, A., Botskariova, S., Kritikou, M., Goh, C., Price, D., Papadopoulos, N., Mathioudakis, A. Tags: 07.02 - Paediatric asthma and allergy Source Type: research

Paediatric breath VOC analysis using the ReCIVA breath sampler and batch effects
Conclusion: The ReCIVA seems to be an effective and appropriate device for standardised breath sampling in the paediatric population. Batch effect analysis showed the factors included did not have a significant influence on the ReCIVA sample VOC panels.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Bhavra, K., Wilde, M., Richardson, M., Cordell, R., Thomas, P., Zhao, B., Bryant, L., Brightling, C., Ibrahim, W., Salman, D., Siddiqui, S., Monks, P., Gaillard, E. Tags: 07.02 - Paediatric asthma and allergy Source Type: research

Management of Severe Asthma in Pediatric Patients by an Interdisciplinary Team in a Public Hospital Setting.
Conclusion: Implementing this type of interdisciplinary program was associated with a marked improvement in all modifiable variables of asthma in patients with SDCA, leading to better management of UCSA patients.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Teijeiro, A., Vieyra, R., Arteaga, A., Ermoli, M., Bustos, C., Soria, F., Yanez, A. Tags: 07.02 - Paediatric asthma and allergy Source Type: research

A feasibility study of a school-based asthma programme in Malaysia conducted during COVID-19 pandemic
Conclusions: The school-based intervention was feasible, though restricted by the pandemic. Although remote health programmes gained popularity during the pandemic, widespread use could disadvantage children from lower socio-economic backgrounds who had limited access to the electronic devices/ and the internet.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Ramdzan, S. N., Khoo, E. M., Liew{dagger}, S. M., Cunningham, S., Pinnock, H., Khoo, E. M. Tags: 07.02 - Paediatric asthma and allergy Source Type: research

Biomarker-defined clusters by level of Type 2 inflammatory involvement in severe asthma
Conclusions: In line with previous findings, a cluster with females and low biomarkers suggested low T2 involvement. The other 4 clusters varied in biomarker elevations, highlighting the complexity of T2 inflammatory involvement in severe asthma.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Price, D., Burkill, S., Wang, E., E. Wechsler, M., Denton, E., N.Tran, T., Martin, N., Katial, R., Barker, P., Maspero, J., Hew, M., Bruselle, G., C Christoff, G., Sadatsafavi, M., A. Torres-Duque, C., M. Porsbjerg, C., Ulrik, C., Hansen, S., Altraja, A., Tags: 05.01 - Airway pharmacology and treatment Source Type: research

Efficacy and safety of Phlai capsule for allergic rhinitis: a randomized, double-blind, placebo-controlled study
Conclusion: In patients with AR, Phlai capsules can be a potential adjunct treatment to improve symptoms, especially rhinorrhea, IS, and IE. Phlai was safe and well-tolerated.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Hoang, M. P., Seresirikachorn, K., Kerr, S., Kanjanaumporn, J., Aeumjaturapat, S., Chusakul, S., Samuthpongtorn, J., Chitsuthipakorn, W., Kasemsiri, P., Kirtsreesakul, V., Prasittivatechakool, K., Tantilipikorn, P., Poachanukoon, O., Snidvongs, K. Tags: 05.03 - Allergy and immunology Source Type: research

Feasibility of Airwave Oscillometry in Preschool Children with Acute Wheeze in the Emergency Department
Conclusions: AOS measurements are feasible in preschool children with acute wheeze in the ED. Using AOS 7-41Hz resulted in a greater proportion of usable measurements likely because the high respiratory rate in acutely wheezy preschool children interferes with the lower 5Hz frequency.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Alshlowi, M., Devani, P., Alraimi, A., Beardsmore, C., Gaillard, E. Tags: 07.02 - Paediatric asthma and allergy Source Type: research

Comparison of upper and lower airway expression of SARS-COV-2 receptors in mild allergic asthmatics
Conclusion: Overall, ACE2 is more highly expressed in endobronchial tissue versus nasal tissue, suggesting SARS-CoV-2 may more readily infect lower versus upper airways. It is unknown whether the higher expression of ACE2 and ACE2+TMPRSS2 observed in the airways of mild allergic asthmatic donors versus control donors translates to higher susceptibility to infection.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Ranjbar, M., Whetstone, C., Cusack, R., Al-Sajee, D., Alsaji, N., OByrne, P., Sehmi, R., Gauvreau, G. Tags: 05.03 - Allergy and immunology Source Type: research

Association of tuberculosis infection with asthma in a european multinational cohort
Conclusion: Our study showed that TB infection was associated with asthma, in particular non-allergic asthma. Longitudinal analyses are needed to further explore these results.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Gyawali, S., Lopez Cervantes, J. P., Mustafa, T., Svanes, C., Shigdel, R. Tags: 06.01 - Epidemiology Source Type: research

One-year treatment with benralizumab in patients with eosinophilic granulomatosis with polyangiitis
Conclusions: These data support the effectiveness of Benralizumab in patients with EGPA and severe eosinophilic asthma. Benralizumab seems to affect not only peripheral blood eosinophilia but also ANCAs production and OCS requirements, preventing organ damage, improving respiratory function and quality of life.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Scarano, P., Cisternino, C., Lo Muzio, G., Calo, O., Sanna, A., Steffanina, A., De Filippis, F., Leporini, M. T., Palange, P., Graziani, E. Tags: 05.03 - Allergy and immunology Source Type: research

Dupilumab efficacy in children with uncontrolled type 2 asthma with baseline high/medium ICS dose
Conclusion: DPL demonstrated clinical efficacy in both ICS groups, with reductions in AER in both groups, and significant and numeric improvements in ppFEV1 in the med- and high-dose ICS groups, respectively.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Maspero, J. F., Antila, M. A., Jain, N., Deschildre, A., Bacharier, L. B., Altincatal, A., Laws, E., Akinlade, B., Siddiqui, S., Jacob-Nara, J. A., Deniz, Y., Rowe, P. J., Lederer, D. J., Hardin, M. Tags: 07.02 - Paediatric asthma and allergy Source Type: research

Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function
In this study, we aimed to study if prenatal exposure to plastic compounds had effects on long-term respiratory health outcomes from early childhood into adulthood.Maternal serum samples collected from pregnant women participating in the Raine Study were assayed for BPA and a range of phthalate metabolites. The children of these women were followed up at 5,13 and 22 years. At each follow-up the children underwent spirometry. Respiratory questionnaires were used to determine asthma status and phenotypes. Lung function trajectories were plotted from longitudinal spirometry measurements Mixed-effects logistic and linear ...
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Foong, R., Sanna, F., Franklin, P., Hall, G., Sly, P., Thorstensen, E., Doherty, D., Keelan, J., Hart, R. Tags: 07.02 - Paediatric asthma and allergy Source Type: research

How consistent are blood eosinophil counts in a general population?
Conclusion: In the GP and in a HSP the overall proportion of high EOSb is small. Also, the longitudinal consistency of EOSb values is high, which may strengthen the value of a single measurement of EOSb as a biomarker.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Hartl, S., Breyer, M. K., Burghuber, O., Schiffers, C., Puchhammer, P., Ofenheimer, A., Breyer-Kohansal, R. Tags: 05.02 - Monitoring airway disease Source Type: research