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Total 415 results found since Jan 2013.
Impact of newborn screening for SCID on the management of congenital athymia
Newborn screening (NBS) programmes for severe combined immunodeficiency (SCID) facilitate early SCID diagnosis and promote early treatment with haematopoietic stem cell transplantation, resulting in improved clinical outcomes. Infants with congenital athymia are also identified through NBS due to severe T-cell lymphopaenia. With the expanding introduction of NBS programmes, referrals of athymic patients for treatment with thymus transplantation have recently increased at Great Ormond Street Hospital (GOSH), London, United Kingdom.
Source: Journal of Allergy and Clinical Immunology - September 5, 2023 Category: Allergy & Immunology Authors: Evey Howley, Zainab Golwala, Matthew Buckland, Federica Barzaghi, Sujal Ghosh, Scott Hackett, Rosie Hague, Fabian Hauck, Ursula Holzer, Adam Klocperk, Minna Koskenvuo, Nufar Marcus, Antonio Marzollo, Malgorzata Pac, Jan Sinclair, Carsten Speckmann, Maarja Source Type: research
UK ' s First Living Donor Uterus Transplant a Success UK ' s First Living Donor Uterus Transplant a Success
After 25 years ' preclinical research, a British surgical team reported the UK ' s first living donor uterus transplant, with both donor and recipient doing well 10 weeks post-operatively.Medscape News UK
Source: Medscape Allergy Headlines - August 23, 2023 Category: Allergy & Immunology Tags: Ob/Gyn & Women ' s Health Source Type: news
GSE231590 Identification of cow milk epitopes to characterize and quantify disease-specific T cells in allergic children
Contributors : Sloan A Lewis ; Aaron Sutherland ; Ferran Soldevilla ; Luise Westernberg ; Minori Aoki ; April Frazier ; Synaida Maiche ; Mich Erlewyn-Lajeunesse ; Hasan Arshad ; Stephanie Leonard ; Susan Laubach ; Jennifer A Dantzer ; Robert A Wood ; Alessandro Sette ; Gregory Seumois ; Pandurangan Vijayanand ; Bjoern PetersSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCow milk (CM) allergy is the most prevalent food allergy in young children in the US and Great Britain. Current diagnostic tests are either unreliable (IgE, skin prick test), or resource-intensive with risks (food cha...
Source: GEO: Gene Expression Omnibus - August 10, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Epinephrine autoinjectors
The debate on who should be prescribed epinephrine and how many autoinjector devices should be carried by individuals with food allergy is ongoing and remains controversial, with some areas of the westernized world recommending at least a 2-pack (United States) and other areas (United Kingdom, Australia) having specific criteria and recommendations for epinephrine prescription, with single devices also available. Taking into account that most patients who are prescribed epinephrine —more often than not—do not carry their devices with them,1 this conversation may be considered moot by some, whereas others will argue tha...
Source: Annals of Allergy, Asthma and Immunology - August 1, 2023 Category: Allergy & Immunology Authors: Aikaterini Anagnostou Tags: Editorial Source Type: research
‘Hypoallergenic’ items sold at Superdrug and Boots fail allergy test
One in three products including shampoos, deodorants and wet wipes found to contain skin allergensMore than a third of personal care products, such as shampoos and body washes, marketed as hypoallergenic at Boots and Superdrug have been found to contain common skin allergens, research shows.As a large proportion of the population have sensitive skin or allergies, products are increasingly using the term “hypoallergenic” to advertise goods. But the British Association of Dermatologists said there needed to be more regulation as some brands were stretching the “terms to their limit” and could not match these claims.Continue reading...
Source: Guardian Unlimited Science - June 26, 2023 Category: Science Authors: Sarah Marsh Tags: Allergies Retail industry Skincare UK news Business Health Boots Medical research Consumer affairs Pharmaceuticals industry Science Money Consumer rights Source Type: news
Penicillin de-labelling in vancouver, British Columbia, Canada: comparison of approaches, outcomes and future directions
Inaccurate penicillin allergy labels lead to inappropriate antibiotic prescriptions and harmful patient consequences. System-wide efforts are needed to remove incorrect penicillin allergy labels, but more heal...
Source: Allergy, Asthma and Clinical Immunology - April 18, 2023 Category: Allergy & Immunology Authors: Sujen Saravanabavan, Amneet Aulakh, Josh Douglas, Chelsea Elwood, Stephanie Erdle, Jennifer Grant, Kristopher T. Kang, Natasha Kwan, Katie Lacaria, Tim T. Y. Lau, Colin Lee, Victor Leung, Yu-Chen Lin, Allison Mah, Anne Nguyen, Vanessa Paquette & hellip; Tags: Research Source Type: research
Investigating the effect of early life antibiotic use on asthma and allergy risk in over 600 000 Canadian children: a protocol for a retrospective cohort study in British Columbia and Manitoba
This study will investigate the relationship between infant antibiotic use and risk of allergic conditions in British Columbian and Manitoban children born over 10 years, adjusting for relevant confounders.
Methods and analysis
Provincial administrative datasets will be linked to perform comparable retrospective cohort analyses, using Population Data BC and the Manitoba Population Research Data Repository. All infants born between 2001 and 2011 in BC and Manitoba will be included (approximately 460 000 and 162 500 infants, respectively), following up to age 7. Multivariable logistic regression will determine the outcome r...
Source: BMJ Open - April 4, 2023 Category: General Medicine Authors: Lishman, H., Nickel, N. C., Sbihi, H., Xie, M., Mamun, A., Zhang, B. Y., Rose, C., Janssen, P., Roberts, A., Azad, M. B., Turvey, S., Patrick, D. M. Tags: Open access, Paediatrics Source Type: research
"Here's your EpiPen, good luck to you". The Healthcare Experiences And Psychological Support Needs Of Adults Living With Food Allergies in The United Kingdom
Food allergy (FA) is commonly associated with psychological distress, but less is known about experiences with psychological support for this patient group. As part of the Global Access to Psychological Services for Food Allergy Study (GAPS), we explored experiences with psychological support and access to psychological services for adults with FA in the United Kingdom.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Mary Jane Marchisotto, Caity Roleston, Helen Brough, Linda Herbert, Christine Jones, Lisa Lombard, Christopher Warren, Jennifer Protudjer, Alexandra Santos, Brian Vickery, Ruchi Gupta, Cassandra Screti, Rebecca Knibb Source Type: research
Comparison of the Accuracy of NOVEOS vs ImmunoCAP in Two UK NEQAS Samples for Specific IgE: Impact of Cross-reactive Carbohydrate Determinants
Up to 30% of the general population develops IgE against cross-reactive carbohydrate determinants (CCDs) found in insect venoms and plants and as a result are at risk of receiving false positive test results from specific IgE (sIgE) immunoassays. ImmunoCAP utilizes a cellulose-based matrix that is known to contain CCD N-glycans that bind to anti-CCD IgE antibodies. This abstract reports on the analysis and resolution of discordant results between NOVEOS and ImmunoCAP in two recent United Kingdom based National External Quality Assessment Service (UK NEQAS) samples.
Source: Journal of Allergy and Clinical Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Elisabeth Laderman, Deanna Kha, Monique Perez, Andrea Cruz-Campos, Brittany Braddock Source Type: research
Safety and savings from penicillin allergy de-labelling in pregnancy: good stewardship, good cents
Studies have shown that 80-95% of pregnant patients who report a penicillin allergy can be safely de-labelled. A pencillin allergy has been associated with poor obstetric outcomes, low rates of appropriate antibiotic prescribing and additional healthcare system costs. In a cohort of patients in British Columbia, Canada, who underwent penicillin de-labelling in pregnancy we present safety data and calculations of the lifetime savings following de-labelling.
Source: American Journal of Obstetrics and Gynecology - January 13, 2023 Category: OBGYN Authors: Atkinson A, Zhang BY, Mak R, Paquette V, Dionne F, Watt M, Erdle S, Van schalkwyk J, Wong T, Poliquin V, Elwood C Source Type: research
Cobalt nanoparticles cause allergic contact dermatitis in humans
CONCLUSIONS: CoNPs potently elicit immune responses in Co-sensitized individuals. Even though patch testing with CoNPs resulted in a lower skin dose than CoCl2, identical immunological profiles were present. Further research is needed to identify the potential harm of CoNPs to human health.PMID:36637098 | DOI:10.1093/bjd/ljac043
Source: The British Journal of Dermatology - January 13, 2023 Category: Dermatology Authors: Klara Midander Paulina Werner Marl éne Isaksson Lukas Wisgrill Carola Lid én Nanna Fyhrquist Anneli Julander Source Type: research
Knowledge mapping of immunotherapy for allergic rhinoconjunctivitis: a bibliometric study (2002-2021)
CONCLUSION: Over the past 20 years, the overall quality of research on immunotherapy for ARC has gradually improved, allowing the introduction of specific and targeted treatment. Currently, the main focus of ARC research is the novel routes of drug delivery and combined treatment with biological agents.PMID:36617823 | DOI:10.15586/aei.v51i1.714
Source: Allergologia et Immunopathologia - January 9, 2023 Category: Allergy & Immunology Authors: Na Chen Kun Zhang Youwei Li Ying Liu Source Type: research
