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Total 1196 results found since Jan 2013.

Sex differences in clinical manifestations of hospitalized patients with eosinophilic granulomatosis with polyangiitis: a retrospective cohort study
CONCLUSION: In this Chinese EGPA cohort, male and female patients showed distinct disease phenotypes. Male patients with EGPA had a higher disease activity at diagnosis and required more aggressive treatment for remission induction.PMID:37263648 | DOI:10.3899/jrheum.2022-1117
Source: J Rheumatol - June 1, 2023 Category: Rheumatology Authors: Suying Liu Linna Han Mengtao Li Xinping Tian Xiaofeng Zeng Yuewu Lu Li Wang Fengchun Zhang Source Type: research

Translation, cross ‐cultural adaptation and validation of the traditional Chinese Food Allergy Quality of Life‐Parental Burden questionnaire into simplified Chinese for use in mainland China
AbstractAimThe study aimed to translate and adapt the traditional Chinese Food Allergy Quality of Life-Parental Burden Questionnaire (TC-FAQL-PB) into simplified Chinese language and determine the validity and reliability of the translated version.DesignA methodologic study design involving instrument translation and psychometric evaluation was used for the present study.MethodsThe simplified Chinese FAQL-PB (SC-FAQL-PB) was developed following Guillemin's guidelines for cross-cultural adaptation. A convenience sample of 230 participants was recruited. The psychometric properties were examined using internal consistency, t...
Source: Nursing Open - May 12, 2023 Category: Nursing Authors: Zeen Li, Tingfan Leung, Lang Tian, Haiyan Liu, Wei He, Siyuan Tang, Qirong Chen, Guiyun Wang Tags: EMPIRICAL RESEARCH QUANTITATIVE Source Type: research

NIH restarts bat virus grant suspended 3 years ago by Trump
Three years after then-President Donald Trump pressured the National Institutes of Health (NIH) to suspend a research grant to a U.S. group studying bat coronaviruses with partners in China, the agency has restarted the award. The new 4-year grant is a stripped-down version of the original grant to the EcoHealth Alliance, a nonprofit research organization in New York City, providing $576,000 per year. That 2014 award included funding for controversial experiments that mixed parts of different bat viruses related to severe acute respiratory syndrome (SARS), the coronavirus that sparked a global outbreak in 2002–04, a...
Source: ScienceNOW - May 8, 2023 Category: Science Source Type: news

Risk Assessment of Allergic Diseases Among Preschool Children in Guangzhou, China: A Cross-Sectional Study
Source: Journal of Asthma and Allergy - May 5, 2023 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Efficacy and safety of atropine in myopic children: A meta-analysis of randomized controlled trials
CONCLUSIONS: Atropine in various concentrations can effectively slow myopia progression in children, and its effect is dose-dependent, while low-dose atropine (0.01% atropine) appears to be safer.PMID:37147148 | DOI:10.1016/j.jfo.2023.01.030
Source: Journal Francais d Ophtalmologie - May 5, 2023 Category: Opthalmology Authors: H Long M H Shi X Li Source Type: research

Arsenic exposure and pruritus: evidence from observational, interventional, and Mendelian randomization studies
CONCLUSION: Arsenic exposure is associated with pruritus, and β-endorphin serves as a biomarker of pruritus. Naloxone relieves pruritus in patients with arseniasis.PMID:37129453 | DOI:10.1111/all.15758
Source: Cancer Control - May 2, 2023 Category: Cancer & Oncology Authors: Xiaoyan Huang Yi Xiao Danrong Jing Yuzhou Huang Songchun Yang Zhijun Huang Guoping Yang Yanying Duan Meian He Juan Su Mingliang Chen Xiang Chen Minxue Shen Source Type: research

The reason and mechanism of propylene glycol alginate sodium sulfate (PSS) mediated allergic side effect
Int J Biol Macromol. 2023 Apr 27:124638. doi: 10.1016/j.ijbiomac.2023.124638. Online ahead of print.ABSTRACTPropylene glycol alginate sodium sulfate (PSS) is a heparinoid polysaccharide drug used in clinic for >30 years in China. But its allergy events happened from time to time and should not be ignored. Here, ammonium salt in PSS (PSS-NH4+), PSS fractions with high Mw (PSS-H-Mw) and low mannuronic acid (M) to guluronic acid (G) ratio (PSS-L-M/G) were found to induce allergic response by the structure-activity and impurity-activity relationships in vitro. Furthermore, we confirmed the reason and elucidated the mechanis...
Source: International Journal of Biological Macromolecules - April 29, 2023 Category: Biochemistry Authors: Yi-Ting Xue Shuang Li Xin-Yang Jiang Meng Xin Hai-Hua Li Guang-Li Yu Xiao-Xi He Chun-Xia Li Source Type: research

Evaluation of Safety, Efficacy, and Compliance of Intralymphatic Immunotherapy for Allergic Rhinoconjunctivitis: A Systematic Review and Meta-Analysis
Conclusion: ILIT was a safe and effective treatment for ARC and could achieve comparable clinical improvement with SCIT with shorter duration and higher compliance. Moreover, ILIT was safer than SCIT.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - April 27, 2023 Category: Allergy & Immunology Source Type: research

Serological analysis of allergic components of house dust mite provides more insight in epidemiological characteristics and clinical symptom development in North China
ConclusionHDM groups 1 and 2 were the major sensitizing allergens, with group 2 being the most important component relevant to respiratory symptoms in North China. The Der p 10 sensitization tends to increase with age. Der p 21 and Der p 23 might be associated with the development of allergic skin disease and asthma, respectively. Multiple allergen sensitizations increased the risk of allergic asthma.
Source: Frontiers in Immunology - April 27, 2023 Category: Allergy & Immunology Source Type: research

Immunomodulatory effects of modified Liu-Wei-Di-Huang-Wan Traditional Chinese medicine on allergic asthmatic mice
Allergic asthma occurs worldwide and is particularly prevalent in westernized countries characterized by chronic airway inflammation resulting in airway hyperresponsiveness. The house dust mites (HDM) including D...
Source: Allergy, Asthma and Clinical Immunology - April 26, 2023 Category: Allergy & Immunology Authors: Jaw-Ji Tsai, Chung-Yang Yen, Chun-Hsien Hsu, Sheng-Jie Yu, Chao-Hsien Chen and En-Chih Liao Tags: Research Source Type: research

Effects of pollen concentration on allergic rhinitis in children: A retrospective study from Beijing, a Chinese megacity
Environ Res. 2023 Apr 18:115903. doi: 10.1016/j.envres.2023.115903. Online ahead of print.ABSTRACTWith global climate change and rapid urbanization, the prevalence of allergic diseases caused by pollen is rising dramatically worldwide with unprecedented complexity and severity, especially for children in mega-cities. However, because of the lack of long time-series pollen concentrations data, the accurate evaluation of the impact of pollen on allergic rhinitis (AR) was scarce in the Chinese metropolis. A generalized additive model was used to assess the effect of pollen concentration on pediatric AR outpatient visits in Be...
Source: Environmental Research - April 18, 2023 Category: Environmental Health Authors: Yuxin Zhao Zhaobin Sun Li Xiang Xingqin An Xiaoling Hou Jing Shang Ling Han Caihua Ye Source Type: research

Allergen Sensitization in Children in Weifang, China: Differences Between Monosensitization and Polysensitization
Source: Journal of Asthma and Allergy - April 14, 2023 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research