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Condition: Hay Fever
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Total 6645 results found since Jan 2013.
Effect of Neurokinin-1 Receptor Knockdown on the Expression of RANTES in Allergic Rhinitis
Am J Rhinol Allergy. 2023 Jul 31:19458924231191012. doi: 10.1177/19458924231191012. Online ahead of print.ABSTRACTBACKGROUND: Neurokinin-1 receptor (NK-1R) and normal T cell expressed and secreted (RANTES) have been shown to play important roles in allergic rhinitis (AR). However, whether the regulating effect of NK-1R in AR is achieved via RANTES remains unknown.METHODS: In the present study, Sprague-Dawley rats were sensitized and challenged with ovalbumin to make AR models. During the challenge period, the rats were treated intranasally with NK-1R-specific small interfering RNA (siRNA) for NKR group, negative siRNA for ...
Source: American Journal of Rhinology and Allergy - August 1, 2023 Category: ENT & OMF Authors: Hong Wang Jing Wu Ruxin Zhang Source Type: research
Insights into mechanisms of immunotherapy circa 1943: “What has been will be again”
Commentary on: “The presence of thermostable inhibiting factor in the sera of patients treated for hay fever by injections of pollen extract.” Annals of Allergy. May-June, 1944, pp. 207-229. Ethan Allen Brown, MD, and Captain Eugene M Holden, MD.1
Source: Annals of Allergy, Asthma and Immunology - August 1, 2023 Category: Allergy & Immunology Authors: Larry Borish Tags: Special Perspective Source Type: research
Nasal IL-13 production identifies patients with late-phase allergic responses
Allergic rhinitis is a major health problem that is increasing in global incidence, affecting about 30% of the world population.1
Source: Journal of Allergy and Clinical Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Nicholas J. Campion, Sergio Villazala-Merino, Ryan S. Thwaites, Victoria Stanek, Helen Killick, Eleftheria Pertsinidou, Mohammed Zghaebi, Josef Toth, Renate Fr öschl, Thomas Perkmann, Katharina Gangl, Sven Schneider, Robin Ristl, Ian C. Scott, Emma Suzan Source Type: research
Evidence-based use of antihistamines for treatment of allergic conditions
Ann Allergy Asthma Immunol. 2023 Jul 28:S1081-1206(23)00524-0. doi: 10.1016/j.anai.2023.07.019. Online ahead of print.ABSTRACTAvailable since the 1940s, H1-antihistamines are mainstay treatments for allergic conditions such as allergic rhinitis and urticaria. They function as inverse agonists that bind to the H1 receptor to inhibit histamine-induced inflammation. The older, first-generation drugs are no longer recommended for patient use due to their well documented negative side effect profile. Evidence has been accumulating to support a newer generation of H1-antihistamines in oral and intranasal formulations, including ...
Source: Annals of Allergy, Asthma and Immunology - July 30, 2023 Category: Allergy & Immunology Authors: Sophia Linton Lubnaa Hossenbaccus Anne K Ellis Source Type: research
Effects of the immunoglobulin/histamine complex on panic disorder concurrent with chronic spontaneous urticaria: a case report
ConclusionsThe immunoglobulin/histamine complex was effective in treating CSU and concomitant panic disorder in this patient and could be effective in treating some types of panic disorder. Considering the mechanisms of action of histamine and the immunoglobulin/histamine complex together with the patient ’s clinical progress, histamine seemed to be related to panic disorder in this case. The concept of histamine-mediated syndromes, including allergies and psychiatric disorders, shows that a wider disease identity may be needed. Further studies on the immunopathogenesis of panic disorder and the me chanisms of action of ...
Source: Journal of Medical Case Reports - July 28, 2023 Category: General Medicine Source Type: research
Audiological Profile in Allergic Rhinitis, a Hospital Based Study
This study was concluded that there is correlation between the severity of the hearing loss and d uration of allergic rhinitis.
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - July 27, 2023 Category: ENT & OMF Source Type: research
Environmental Risk Factors, Protective Factors, and Biomarkers for Allergic Rhinitis: A Systematic Umbrella Review of the Evidence
This study is registered in PROSPERO (CRD42022384320).
Source: Clinical Reviews in Allergy and Immunology - July 25, 2023 Category: Allergy & Immunology Source Type: research
Intramuscular corticosteroid injections should be an option under the policy level recommendation in the international consensus statement on allergic rhinitis
Source: International Forum of Allergy and Rhinology - July 22, 2023 Category: Allergy & Immunology Authors: Jacob Alexander Ru,
Ahmed Bayoumy Bayoumy Tags: LETTER TO THE EDITOR Source Type: research
Eosinophilic granulomatosis with polyangiitis presenting as aspirin –exacerbated respiratory disease
Eosinophilic granulomatosis with polyangiitis (EGPA) is a multisystem disorder causing granulomatous inflammation of both small- and medium-sized arteries with hypereosinophilia and eosinophilic systemic tissue infiltration. EGPA can involve the lungs, sinuses, kidneys, heart, nervous system, intestinal tract, or skin.1 Onset is usually between the third and fifth decades of life with the following 3 stages: the prodromal stage with atopic diseases, that is, allergic rhinitis and asthma; the eosinophilic stage where organs become infiltrated with eosinophils and peripheral blood hypereosinophilia; and the final vasculitic ...
Source: Annals of Allergy, Asthma and Immunology - July 22, 2023 Category: Allergy & Immunology Authors: Sabrina D. Herzberg, Alyssa M. Bosso, Neel R. Sangal, John V. Bosso Tags: Letters Source Type: research
Can development of asthma and bronchial hyperreactivity be reduced by subcutaneous immunotherapy in adult patients with allergic rhinitis?
In this study, data was recorded for patients with a mite and/or grasses/cereals pollen allergy who were tested for BHR before planned SCIT, and who had allergic rhinitis, with or without asthma. The SCIT group was selected as those who received SCIT for at least one year. The control group was selected from those who were scheduled to receive SCIT but were waived and still receiving medication. Symptom scores, prick test results, PC20 levels (methacholine challenge that is a provocative concentration causing a 20% fall in FEV1), and the presence of asthma were recorded and compared with data from at least one year after t...
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Fatma Merve Tepetam Cihan Örçen Zeynep Ferhan Özşeker Dildar Duman Sema Sara ç Source Type: research
