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Sensitization to nut allergens in children with food allergy and other atopic diseases - just a coexistence?
CONCLUSIONS: The analysis of sensitization patterns may help to identify patients with an increased risk, and gives the opportunity to introduce more effective prophylaxis. However, since even the first exposure to nuts may be sufficient to trigger the anaphylaxis, this risk should be considered as a serious issue at any age.PMID:37545822 | PMC:PMC10399669 | DOI:10.5114/ada.2023.128991
Source: Advances in Dermatology and Allergology - August 7, 2023 Category: Dermatology Authors: Klementyna Łyżwa Magdalena Chojnowska-W ójtowicz Joanna Zieli ńska Wioletta Zag órska Marek Kulus Katarzyna Grzela Source Type: research
Diabetes Mellitus and Bone Mineral Density on Fracture Risk in Allergic Rhinitis and Asthma Patients
Asthma (AS) and allergic rhinitis (AR) are the most common allergic diseases, affecting more than 20% of the population.1, 2 In Taiwan, the prevalence rates of asthma and AR were 11.9% and 26.3%, respectively.3 Almost 50% of patients with allergic disease had AR and AS concomitantly.3 Asthma patients have even greater rate of fracture and osteoporosis.1,4 However, there are inconsistencies and contradictions regarding the possible harmful effects of inhaled corticosteroid treatment, such as decreased bone mineral density (BMD) and enhanced fracture risk in asthma patients, based on some review studies.
Source: Annals of Allergy, Asthma and Immunology - August 7, 2023 Category: Allergy & Immunology Authors: Chun-Sheng Hsu, Yi-Ming Chen, Chiann-Yi Hsu, Ya-Lian Deng, Yu-Wen Chu Tags: Letters Source Type: research
Diabetes mellitus and bone mineral density on fracture risk in patients with allergic rhinitis and asthma
Asthma (AS) and allergic rhinitis (AR) are the most common allergic diseases, affecting more than 20% of the population.1,2 In Taiwan, the prevalence rates of AS and AR were 11.9% and 26.3%, respectively.3 Almost 50% of patients with allergic disease had AR and AS concomitantly.3 Patients with AS have even greater rate of fracture and osteoporosis.1,4 However, there are inconsistencies and contradictions regarding the possible harmful effects of inhaled corticosteroid treatment, such as decreased bone mineral density (BMD) and enhanced fracture risk in patients with AS, based on some review studies.
Source: Annals of Allergy, Asthma and Immunology - August 7, 2023 Category: Allergy & Immunology Authors: Chun-Sheng Hsu, Yi-Ming Chen, Chiann-Yi Hsu, Ya-Lian Deng, Yu-Wen Chu Tags: Letters Source Type: research
Climate Change and Food Allergy
The role of environmental factors including climate change and consequent influences of air pollution on food allergy remains less explored compared with impacts on allergic rhinitis and asthma. In this review, we discuss the epithelial barrier hypothesis as a proposed mechanism of food allergy development that may be relevant in this context. We also discuss existing studies that provide insight into the intricate relationship between food allergy and climate-related environmental factors.
Source: Immunology and Allergy Clinics of North America - August 7, 2023 Category: Allergy & Immunology Authors: Ashley Sang Eun Lee, Nicole Ramsey Source Type: research
Intramuscular corticosteroid injections should be an option under the policy level recommendation in the International Consensus Statement on Allergic Rhinitis
Source: International Forum of Allergy and Rhinology - August 5, 2023 Category: Allergy & Immunology Authors: Sarah K. Wise,
Fuad Baroody Tags: REPLY Source Type: research
TSLP Induces Epithelial-Mesenchymal Transition in Nasal Epithelial Cells From Allergic Rhinitis Patients Through TGF- β1/Smad2/3 Signaling
CONCLUSION: TSLP-induced HNECs to undergo the EMT process via TGF-β1-mediated Smad2/3 activation. TSLP is an activator of the EMT in HNECs and might be a potential target for inhibiting EMT and reducing airway remodeling in AR.PMID:37537875 | DOI:10.1177/19458924231193154
Source: American Journal of Rhinology and Allergy - August 4, 2023 Category: ENT & OMF Authors: Hong Wei Yu Wei Wei Wang Qian Jing Yong Liang Pan Source Type: research
Effect of Neurokinin-1 Receptor Knockdown on the Expression of RANTES in Allergic Rhinitis
Am J Rhinol Allergy. 2023 Jul 31:19458924231191012. doi: 10.1177/19458924231191012. Online ahead of print.ABSTRACTBACKGROUND: Neurokinin-1 receptor (NK-1R) and normal T cell expressed and secreted (RANTES) have been shown to play important roles in allergic rhinitis (AR). However, whether the regulating effect of NK-1R in AR is achieved via RANTES remains unknown.METHODS: In the present study, Sprague-Dawley rats were sensitized and challenged with ovalbumin to make AR models. During the challenge period, the rats were treated intranasally with NK-1R-specific small interfering RNA (siRNA) for NKR group, negative siRNA for ...
Source: American Journal of Rhinology and Allergy - August 1, 2023 Category: ENT & OMF Authors: Hong Wang Jing Wu Ruxin Zhang Source Type: research
