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Total 6645 results found since Jan 2013.

The Olink proteomics profile in nasal secretion of patients with allergic rhinitis
Key points Nasal secretions of allergic rhinitis patients were analyzed by Olink proteomics. Fifteen differentially expressed proteins (DEPs) were identified. The DEPs were significantly correlated with the total nasal symptom scores of patients with allergic rhinitis.
Source: International Forum of Allergy and Rhinology - September 22, 2023 Category: Allergy & Immunology Authors: Haotao Zeng, Jiangqi Liu, Lihua Mo, Minyao Li, Aifa Tang, Xianhai Zeng, Miao Zhao, Pingchang Yang Tags: RESEARCH NOTE Source Type: research

Prenatal dietary exposure to chemicals and allergy or respiratory diseases in children in the EDEN mother-child cohort
CONCLUSION: Prenatal dietary exposure to chemicals was associated with risk of allergic rhinitis or wheezing up to age 8 y. A few chemicals were associated with other allergic and respiratory diseases. Larger prospective studies are needed to confirm these findings.PMID:37734145 | DOI:10.1016/j.envint.2023.108195
Source: Environment International - September 21, 2023 Category: Environmental Health Authors: Manel Ghozal Manik Kadawathagedara Rosalie Delvert Karine Adel-Patient Muriel Tafflet Isabella Annesi-Maesano Am élie Crépet V éronique Sirot Marie Aline Charles Barbara Heude Blandine de Lauzon-Guillain Source Type: research

Management of Mechanical Nasal Obstruction Isolated or Associated to Upper Airway Inflammatory Diseases in Real Life: Use of both Subjective and Objective Criteria
AbstractPurpose of ReviewMechanical nasal obstruction (MNO) is a prevalent condition with a high impact on patient ’s quality-of-life (QoL) and socio-economic burden. The aim of this study was to determine the usefulness of both subjective and objective criteria in the appropriate management of MNO, either alone or associated to upper airway inflammatory diseases such as allergic rhinitis (AR) or chronic rhino sinusitis with nasal polyps (CRSwNP).Recent FindingsA long debate persists about the usefulness of subjective and objective methods for making decisions on the management of patients with nasal obstruction. Establi...
Source: Current Allergy and Asthma Reports - September 19, 2023 Category: Allergy & Immunology Source Type: research

Analysis of common allergens affecting patients with allergic rhinitis
This study aimed to identify the common allergens affecting patients with AR. A total of 52 patients with AR were identified for this study. AR was diagnosed based on the presenting symptoms and measurement of IgE levels and absolute eosinophil counts. Skin prick tests (SPT) were performed to identify the allergen sensitivity of the patients. Patient history, family history, and a detailed account of the symptoms were recorded. Finally, correlation between family history and allergy severity was statistically evaluated. All patients presented symptoms of rhinitis with sinusitis and 61.5% of these were mild or moderate alle...
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Kumari Ranjana Maheshwari M Source Type: research

The Assessment of TLR1 Gene Polymorphism Association with the Risk of Allergic Rhinitis in the Chinese Han Population from Northern China
Source: Journal of Asthma and Allergy - September 18, 2023 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Cancers, Vol. 15, Pages 4619: Repurposing Clemastine to Target Glioblastoma Cell Stemness
hristopher J. Pirozzi Yiping He Brain tumor-initiating cells (BTICs) and tumor cell plasticity promote glioblastoma (GBM) progression. Here, we demonstrate that clemastine, an over-the-counter drug for treating hay fever and allergy symptoms, effectively attenuated the stemness and suppressed the propagation of primary BTIC cultures bearing PDGFRA amplification. These effects on BTICs were accompanied by altered gene expression profiling indicative of their more differentiated states, resonating with the activity of clemastine in promoting the differentiation of normal oligodendrocyte progenitor cells (OPCs) into mat...
Source: Cancers - September 18, 2023 Category: Cancer & Oncology Authors: Michael A. Sun Rui Yang Heng Liu Wenzhe Wang Xiao Song Bo Hu Nathan Reynolds Kristen Roso Lee H. Chen Paula K. Greer Stephen T. Keir Roger E. McLendon Shi-Yuan Cheng Darell D. Bigner David M. Ashley Christopher J. Pirozzi Yiping He Tags: Article Source Type: research

Endoscopic vidian and vidian ‐branch neurectomy for refractory allergic rhinitis: A systematic review
ConclusionEVN and vidian-branch neurectomy (including SVN and PNN) are effective treatments, but the former has a higher risk of complications. Additionally, vidian-branch neurectomy with FESS is beneficial for patients with mixed CRSwNP. SVN is a potential approach for patients with coexisting AR and asthma.
Source: International Forum of Allergy and Rhinology - September 16, 2023 Category: Allergy & Immunology Authors: Xun Niu, Yuzhang Chen, Tao Zhou, Hongjun Xiao Tags: REVIEW ARTICLE Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research

Born to wheeze or learned when we were young: maternal and environmental factors influence atopic risk
Trans Am Clin Climatol Assoc. 2023;133:181-192.ABSTRACTThe prevalence of atopic diseases is increasing globally, particularly in children. Heritable genetics can partially explain risk of disease. Evidence also points to acquired genetic material, in the form of the microbiome, as an important factor in disease pathogenesis. The acquisition of the microbiome dynamically changes in response to differences in lifestyle and environmental factors. Also, in utero, maternal and environmental factors influence atopic risk for allergic rhinitis, eczema, asthma, and food allergy. Combining the analytical power of omics, we focus on...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Patricia W Finn David L Perkins Source Type: research