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Loss of Chromosome 3q Is a Prognostic Marker in Fusion-Negative Rhabdomyosarcoma
CONCLUSION: The pathogenesis of STS including FN-RMS remains poorly understood, emphasizing the need for new therapeutic advances and adequate risk stratification. Our data demonstrate that loss of chr3q is associated with poor OS in FN-RMS, supporting it as an important tool for risk stratification.PMID:37738543 | DOI:10.1200/PO.23.00037
Source: Ann Oncol - September 22, 2023 Category: Cancer & Oncology Authors: Carina A Dehner Robert C Bell Yang Cao Kevin He John S A Chrisinger Amy E Armstrong Marielle Yohe Jack Shern Angela C Hirbe Source Type: research

A new anthraquinone derivative from the marine fish-derived fungus < em > Alternaria < /em > sp. X112
Nat Prod Res. 2023 Sep 21:1-6. doi: 10.1080/14786419.2023.2258540. Online ahead of print.ABSTRACTA new anthraquinone, altermodinacid A (1), and five known derivatives, pachybasic acid (2), emodic acid (3), emodin (4), phomarin (5), and 1,7-dihydroxy-3-methylanthracene-9,10-dione (6), were discovered from a halotolerant fungus Alternaria sp. X112 isolated from a marine fish Gadus macrocephalus. Their structures were determined by analysing MS and NMR data. The cytotoxic effect, antiagricultural pathogens activity, antibacterial activity and quorum sensing inhibitory potential of new compound 1 were evaluated.PMID:37732591 |...
Source: Natural Product Research - September 21, 2023 Category: Biochemistry Authors: Xiaoyuan Xu Gang Li Rao Fu Hongxiang Lou Xiaoping Peng Source Type: research

Factors Contributing to Accumulation of < sup > 210 < /sup > Po in Freshwater Fishes in Dong Thai Lake, Vietnam and Radiological Hazard Assessment
This study determined by alpha spectrometry the 210Po activity in sixteen selected fish species with different living behaviors (pelagic, demersal), trophic positions (herbivores, carnivores, omnivorous), and masses in Dong Thai Lake, Hanoi, Vietnam. The min, max, and average of the 210Po concentration of sixteen fish species were 0.80 ± 0.44, 12.7 ± 0.20, and 3.54 ± 0.31 Bq kg-1, respectively. Regarding the different living behaviors, trophic positions, and masses, the results showed trending of 210Popelagic > 210Podemersal; 210Poherbivores < 210Pocarnivores < 210Poomnivorous and 210Po<0.2 kg > 210Po0.2-...
Source: Archives of Environmental Contamination and Toxicology - September 21, 2023 Category: Environmental Health Authors: Van-Hao Duong Trung-Tien Chu Thanh-Nam Nguyen Source Type: research

Pathogens and microorganisms in the mangrove oyster Crassostrea gasar cultivated in an estuarine environment in Northeast Brazil
Braz J Biol. 2023 Sep 15;83:e272789. doi: 10.1590/1519-6984.272789. eCollection 2023.ABSTRACTEstuaries are important ecosystems due to the ecological services they provide, acting as nurseries for many species of fish and invertebrates, and are also used as environments for the extraction and cultivation of mollusks. Oysters are animals that filter water to obtain oxygen and nutrients. In this process, they can bioaccumulate microorganisms and chemical substances in their tissues. The growth of mollusk culture in Northeastern Brazil requires the health identification of cultivated oysters through the quantification of the ...
Source: Braz J Biol - September 20, 2023 Category: Biology Authors: D C S Mendes D T A Rodrigues H M Gomes T M Lenz C M Silva I G Antonio Source Type: research

Generation and application of a novel transgenic zebrafish line Tg(GAcyp1a:eGFP/Luc) as an in vivo assay to sensitive and specific monitoring of DLCs in the environment
In conclusion, a sensitively and specifically transgenic zebrafish line was established to convenient and effective to detect DLCs in the environment.PMID:37729807 | DOI:10.1016/j.ecoenv.2023.115471
Source: Ecotoxicology and Environmental Safety - September 20, 2023 Category: Environmental Health Authors: Shaolin Xie Bing Yang Siying Li Liangjun Ge Min Li Qingshi Chen Xian Qing Jixing Zou Source Type: research

Exhaustive exercise alters native and site-specific H < sub > 2 < /sub > O < sub > 2 < /sub > emission in red and white skeletal muscle mitochondria
Free Radic Biol Med. 2023 Sep 18:S0891-5849(23)00642-1. doi: 10.1016/j.freeradbiomed.2023.09.018. Online ahead of print.ABSTRACTMitochondrial reactive oxygen species (ROS) homeostasis is intricately linked to energy conversion reactions and entails regulation of the mechanisms of ROS production and removal. However, there is limited understanding of how energy demand modulates ROS balance. Skeletal muscle experiences a wide range of energy demand depending on the intensity and duration of exercise and therefore is an excellent model to probe the effect of altered energy demand on mitochondrial ROS production. Because in mo...
Source: Free Radical Biology and Medicine - September 20, 2023 Category: Biology Authors: Collins Kamunde Yashodya Wijayakulathilake Chidozie Okoye Nirmala Chinnappareddy Zahra Kalvani Michael van den Heuvel Ravinder Sappal Don Stevens Source Type: research

Discovery of BbX transcription factor in the patagonian blennie: Exploring expression changes following combined bacterial and thermal stress exposure
Dev Comp Immunol. 2023 Sep 18:105056. doi: 10.1016/j.dci.2023.105056. Online ahead of print.ABSTRACTHigh-Mobility Group (HMG) proteins are involved in different processes such as transcription, replication, DNA repair, and immune response. The role of HMG proteins in the immune response of fish has been studied mainly for HMGB1, where its expression can be induced by the stimulation of viral/bacterial PAMPs and can act as a proinflammatory mediator and as a global regulator of transcription in response to temperature. However, for BbX this role remains to be discovered. In this work, we identified the BbX of E. maclovinus ...
Source: Developmental and Comparative Immunology - September 20, 2023 Category: Allergy & Immunology Authors: Danixa Mart ínez Daniela Nualart Carlos Loncoman Juan C Opazo Kattina Zabala Francisco J Morera Gonzalo A Mardones Luis Vargas-Chacoff Source Type: research

Pathogens and microorganisms in the mangrove oyster Crassostrea gasar cultivated in an estuarine environment in Northeast Brazil
Braz J Biol. 2023 Sep 15;83:e272789. doi: 10.1590/1519-6984.272789. eCollection 2023.ABSTRACTEstuaries are important ecosystems due to the ecological services they provide, acting as nurseries for many species of fish and invertebrates, and are also used as environments for the extraction and cultivation of mollusks. Oysters are animals that filter water to obtain oxygen and nutrients. In this process, they can bioaccumulate microorganisms and chemical substances in their tissues. The growth of mollusk culture in Northeastern Brazil requires the health identification of cultivated oysters through the quantification of the ...
Source: Braz J Biol - September 20, 2023 Category: Biology Authors: D C S Mendes D T A Rodrigues H M Gomes T M Lenz C M Silva I G Antonio Source Type: research

Effects of management objectives and rules on marine conservation outcomes
This article is protected by copyright. All rights reserved.PMID:37728514 | DOI:10.1111/cobi.14156
Source: Conservation Biology - September 20, 2023 Category: Biology Authors: Natalie C Ban Emily S Darling Georgina G Gurney Whitney Friedman Stacy D Jupiter W Peni Lestari Irfan Yulianto Sinta Pardede Sukma A R Tarigan Puji Prihatiningsih Sangeeta Mangubhai Waisea Naisilisili Sirilo Dulunaqio Josheena Naggea Ravaka Ranaivoson Ver Source Type: research

Discovery of BbX transcription factor in the patagonian blennie: Exploring expression changes following combined bacterial and thermal stress exposure
Dev Comp Immunol. 2023 Sep 18:105056. doi: 10.1016/j.dci.2023.105056. Online ahead of print.ABSTRACTHigh-Mobility Group (HMG) proteins are involved in different processes such as transcription, replication, DNA repair, and immune response. The role of HMG proteins in the immune response of fish has been studied mainly for HMGB1, where its expression can be induced by the stimulation of viral/bacterial PAMPs and can act as a proinflammatory mediator and as a global regulator of transcription in response to temperature. However, for BbX this role remains to be discovered. In this work, we identified the BbX of E. maclovinus ...
Source: Developmental and Comparative Immunology - September 20, 2023 Category: Allergy & Immunology Authors: Danixa Mart ínez Daniela Nualart Carlos Loncoman Juan C Opazo Kattina Zabala Francisco J Morera Gonzalo A Mardones Luis Vargas-Chacoff Source Type: research

Effects of management objectives and rules on marine conservation outcomes
This article is protected by copyright. All rights reserved.PMID:37728514 | DOI:10.1111/cobi.14156
Source: Conservation Biology - September 20, 2023 Category: Biology Authors: Natalie C Ban Emily S Darling Georgina G Gurney Whitney Friedman Stacy D Jupiter W Peni Lestari Irfan Yulianto Sinta Pardede Sukma A R Tarigan Puji Prihatiningsih Sangeeta Mangubhai Waisea Naisilisili Sirilo Dulunaqio Josheena Naggea Ravaka Ranaivoson Ver Source Type: research

A Parasitological Examination on Aquarium Fish Sold in Petshops in K ırıkkale
CONCLUSION: The importance of the present study is that highest number of parasite species were detected in aquarium fish sold in pet shops in Türkiye. The aquarium owners should pay attention to the cleanliness of the aquarium water in order to reduce the rate of parasitic infection in fish; when new fish are purchased, they should be taken from reliable sources, and the quarantine process should be observed.PMID:37724365 | DOI:10.4274/tpd.galenos.2023.94840
Source: Turkish Society for Parasitology - September 19, 2023 Category: Parasitology Authors: Sami G ökpınar G özde Nur Akkuş Sinem Akdeniz Source Type: research

Apolipoprotein E isoforms differentially affect LCAT-dependent cholesterol esterification
CONCLUSION: The present results suggest that the apoE2 isoform is associated with a higher LCAT-mediated cholesterol esterification. This observation may contribute to the characterization of the peculiar functional properties of apoE2.PMID:37725860 | DOI:10.1016/j.atherosclerosis.2023.117266
Source: Atherosclerosis - September 19, 2023 Category: Cardiology Authors: Cecilia Vitali Chiara Pavanello Marta Turri Sissel Lund-Katz Michael C Phillips Alberico Luigi Catapano Andrea Baragetti Giuseppe Danilo Norata Fabrizio Veglia Laura Calabresi Source Type: research

The importance of omega-3 polyunsaturated fatty acids as high-quality food in freshwater ecosystems with implications of global change
Biol Rev Camb Philos Soc. 2023 Sep 19. doi: 10.1111/brv.13017. Online ahead of print.ABSTRACTTraditionally, trophic ecology research on aquatic ecosystems has focused more on the quantity of dietary energy flow within food webs rather than food quality and its effects on organisms at various trophic levels. Recent studies emphasize that food quality is central to consumer growth and reproduction, and the importance of food quality for aquatic ecosystems has become increasingly well recognized. It is timely to synthesise these findings and identify potential future research directions. We conducted a systematic review of om...
Source: Biological Reviews of the Cambridge Philosophical Society - September 19, 2023 Category: Biology Authors: Keheng Yan Fen Guo Martin J Kainz Feilong Li Wei Gao Stuart E Bunn Yuan Zhang Source Type: research

Impacts of Some Trace Metals in Cyprinus carpio (Linnaeus,  1758) and Tor soro (Valenciennes, 1842) on Human Health
Biol Trace Elem Res. 2023 Sep 19. doi: 10.1007/s12011-023-03852-4. Online ahead of print.ABSTRACTAlthough fish are rich sources of various trace metals in their bodies, when these metals exceed health safety limits, it becomes a global concern. Fish exposed to trace metal pollution in their aquatic ecosystems can lead to bioaccumulation and transfer to consumers. Monitoring trace metal contamination of fish food is crucial because they can reach humans through the aquatic food chain, resulting in health problems. Therefore, a first attempt was made for the analysis of trace metals in two cyprinid fish species, namely Cypri...
Source: Biological Trace Element Research - September 19, 2023 Category: Biology Authors: Nima Nazeer Zubia Masood Mourad Ben Said Tawseef Khan Asim Ullah Wajid Ali Ayman A Swelum Source Type: research